Treatment options for atypical optic neuritis.

Abstract:

CONTEXT:Optic neuritis (ON) is defined as inflammation of the optic nerve and can have various etiologies. The most common presentation in the US is demyelinating, or "typical" ON, usually associated with multiple sclerosis. This is in contrast to "atypical" causes of ON, which differ in their clinical presentation, management, and prognosis. These atypical cases are characterized by lack of eye pain, exudates, and hemorrhages on exam, very severe, bilateral or progressive visual loss, or with failure to recover vision. AIMS:The aim was to describe the clinical presentations of atypical ON and their treatments. SETTINGS AND DESIGN:Review article. MATERIALS AND METHODS:Literature review. RESULTS:Types of atypical ON identified include neuromyelitis optica, autoimmune optic neuropathy, chronic relapsing inflammatory optic neuropathy, idiopathic recurrent neuroretinitis, and optic neuropathy associated with systemic diseases. Atypical ON usually requires corticosteroid treatment and often will require aggressive immunosuppression. CONCLUSIONS:Unlike demyelinating ON, atypical ON requires treatment to preserve vision.

journal_name

Indian J Ophthalmol

authors

Malik A,Ahmed M,Golnik K

doi

10.4103/0301-4738.145986

subject

Has Abstract

pub_date

2014-10-01 00:00:00

pages

982-4

issue

10

eissn

0301-4738

issn

1998-3689

pii

IndianJOphthalmol_2014_62_10_982_145986

journal_volume

62

pub_type

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