Abstract:
BACKGROUND:Nonmydriatic digital imaging (NMDI) is ideal for screening diabetic retinopathy (DR), but its use in Indian eyes has not been evaluated. AIM:The aim was to evaluate the sensitivity and specificity of NMDI as a screening tool in detecting DR in Indian eyes. DESIGN:A prospective, nonrandomized, noncomparative, noninterventional study. MATERIALS AND METHODS:A total of 500 diabetic patients visiting the endocrinology clinic (September 2008-June 2010) underwent NMDI (Zeiss Procam), followed by routine dilated fundus photography (FP; Zeiss Visupac 450+) of 345° retinal fields (1) optic disc and macula, (2) superotemporal, and (3) nasal to optic disc. Two-masked retina specialists graded the images for quality and severity of DR, and compared between NMDI and dilated FP. STATISTICAL ANALYSIS:SPSS Windows 17 for version. RESULTS:Mean age was 52.97 ± 13.46 years (306 males: 194 females). The rate of ungradable images was 30.6% and 31% by the two observers. By observer 1, the sensitivity and specificity of detecting any DR was 58.8% and 69.1%, respectively, (κ = 0.608) and sight-threatening DR (STDR) was 63.1% and 68.9%, respectively, (κ = 0.641). By observer 2, the sensitivity and specificity was 57.3% and 68.3%, respectively, for any DR (κ = 0.593) and 62.8% and 68.3%, respectively, for STDR (κ = 0.637). The level of agreement between two observers was high (κ = 0.96). CONCLUSION:A high rate of poor quality photographs and low sensitivity limited the use of NMDI as a perfect screening system, particularly in dark iris population with diabetes as seen in Indian eyes.
journal_name
Indian J Ophthalmoljournal_title
Indian journal of ophthalmologyauthors
Gupta V,Bansal R,Gupta A,Bhansali Adoi
10.4103/0301-4738.141039subject
Has Abstractpub_date
2014-08-01 00:00:00pages
851-6issue
8eissn
0301-4738issn
1998-3689pii
IndianJOphthalmol_2014_62_8_851_141039journal_volume
62pub_type
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