当前位置： SCI文献检索 > INDIAN JOURNAL OF OPHTHALMOLOGY期刊下所有文献 > Retinopathy of prematurity in Asian Indian babies weighing greater than 1250 grams at birth: ten year data from a tertiary care center in a developing country.

Retinopathy of prematurity in Asian Indian babies weighing greater than 1250 grams at birth: ten year data from a tertiary care center in a developing country.

Abstract：

BACKGROUND:Retinopathy of prematurity (ROP) is an important cause of childhood blindness in developing countries. AIM:To report the spectrum of ROP and associated risk factors in babies weighing > 1250 g at birth in a developing country. SETTING AND DESIGN:Institutional, retrospective, non-randomized, observational clinical case series. MATERIALS AND METHODS:Retrospective analysis (10 years) of 275 eyes (138 babies) with ROP. STATISTICAL ANALYSIS:Qualitative data with the Chi-square test. Quantitative data using the unpaired t test or the ANOVA and further tested using multivariate logistic regression. RESULTS:The mean birth weight was 1533.9 g (range 1251 to 2750 g) and the mean period of gestation was 30.9 weeks (range 26 to 35). One hundred and twenty-four of 275 eyes (45.1%) had threshold or worse ROP. Risk factors for threshold or worse disease were, 'outborn babies' ( P P = 0.007) and exchange transfusion ( P = 0.003). The sensitivity of the American and British screening guidelines to pick up threshold or worse ROP in our study group was 82.4% and 77.4% respectively. CONCLUSIONS:Severe ROP is often encountered in babies weighing greater than 1250 g at birth in developing countries. Western screening guidelines may require modifications before application in developing countries.

journal_name

Indian J Ophthalmol

journal_title

Indian journal of ophthalmology

authors

Vinekar A,Dogra MR,Sangtam T,Narang A,Gupta A

doi

10.4103/0301-4738.33817

subject

Has Abstract

pub_date

2007-09-01 00:00:00

pages

331-6

issue

5

eissn

0301-4738

issn

1998-3689

journal_volume

55

pub_type

杂志文章

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