Abstract：
PURPOSE:This study was aimed at reporting the outcomes of trabeculectomy in primary juvenile open angle glaucoma (JOAG). DESIGN:This study was a retrospective noncomparative case series. MATERIALS AND METHODS:We included 60 eyes of 41 JOAG patients who underwent primary trabeculectomy without mitomycin-C (MMC) between 1995 and 2007. The primary outcome was success, defined as complete, if intraocular pressure (IOP) was >5 and ≤ 21 mmHg without medications or qualified if IOP was >5 and ≤ 21 mmHg with or without antiglaucoma medications. Secondary outcome measures were mean and percentage IOP reduction, complications, and risk factors for the failure of trabeculectomy. RESULTS:The mean (± standard deviation) age at presentation was 24.1 ± 6.8 years (range, 12-35). Mean follow-up was 67 ± 41 months (range, 12-156). At 1 year, the probability of complete success was 92% (n = 56, 95% CI: 81-96%), at 3 years it was 89% (n = 47, 95% CI: 78-95%), and at the end of 5 years, it was 80% (n = 34, 95% CI: 65-89%). The probability of qualified success was 100% (n = 60) at 1 year, 98% (n = 51, 95% CI: 87-100%) at 3 years, and 96% (n = 36, 95% CI: 84-99%) at the end of 5 years. The mean IOP reduced from 35 ± 10 to 13 ± 2.5 mmHg (P < 0.001) after trabeculectomy. There was no serious postoperative complication. Young age was the only significant risk factor associated with the failure (odds ratio = 0.89, P = 0.03). CONCLUSION:Primary trabeculectomy without MMC has good success rates in JOAG.
journal_name
Indian J Ophthalmoljournal_title
Indian journal of ophthalmologyauthors
Pathania D,Senthil S,Rao HL,Mandal AK,Garudadari CSdoi
10.4103/0301-4738.101074subject
Has Abstractpub_date
2014-02-01 00:00:00pages
224-8issue
2eissn
0301-4738issn
1998-3689journal_volume
62pub_type
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