Advances in pharmacological strategies for the prevention of cataract development.

Abstract:

:Cataractous-opacification of the lens is one of the leading causes of blindness in India. The situation can be managed by surgical removal of the cataractous lens. Various pharmacological strategies have been proposed for the prevention and treatment of cataract. Information on possible benefits of putative anticataract agents comes from a variety of approaches, ranging from laboratory experiments, both in vitro and in vivo , to epidemiological studies in patients. This review deals with the various mechanisms, and possible pharmacological interventions for the prevention of cataract. The article also reviews research on potential anticataractous agents, including aldose reductase inhibitors, glutathione boosters, antiglycating agents, vitamins and various drugs from indigenous sources.

journal_name

Indian J Ophthalmol

authors

Gupta SK,Selvan VK,Agrawal SS,Saxena R

doi

10.4103/0301-4738.49390

subject

Has Abstract

pub_date

2009-05-01 00:00:00

pages

175-83

issue

3

eissn

0301-4738

issn

1998-3689

pii

IndianJOphthalmol_2009_57_3_175_49390

journal_volume

57

pub_type

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