Abstract:
BACKGROUND:The successful lowering of the intraocular pressure after glaucoma filtration surgery depends mostly on the nature of the healing response, which is also the single most important modifiable factor. AIMS:To evaluate and compare the effectiveness of two oxidated regenerated cellulose material, Interceed and Surgicel on wound healing reaction after glaucoma filtration surgery. SETTING AND DESIGN:University hospital, prospective study. MATERIALS AND METHODS:Full thickness filtration surgery was carried out on three groups of rabbits. Interceed and Surgicel was applied in Groups 1 and 2 respectively. The third group was the controls. Intraocular pressure, anterior chamber depth and bleb appearance were checked on the first, third, seventh and 14 th days. The rabbits were sacrificed on the 14 th day and the trabeculectomy area with overlying conjunctiva was excised, fixed, stained and evaluated histopathologically. STATISTICS:The values obtained from the clinical and histopathologic evaluation were statistically analyzed using non-parametric tests (Mann Whitney-U and Kruskall Wallis tests) in SPSS for Windows v-10. P values under 0.05 for statistical significance in comparisons were considered significant. RESULTS:The groups were similar with respect to intraocular pressure, anterior chamber depth, bleb appearance and number of the fibroblasts and neutrophils on the seventh and 14 th days. Mean number of the eosinophils and vessels was significantly less in Groups 1 and 2 ( P = 0.014, P = 0.20 respectively). Macrophages in Group 2 were significantly less than Group 1 ( P = 0.047). CONCLUSION:Both these agents seem to suppress vascularization. Since they have no significant effect on fibroblast proliferation, it is controversial to talk about wound healing modulation.
journal_name
Indian J Ophthalmoljournal_title
Indian journal of ophthalmologyauthors
Akyol N,Akpolat Ndoi
10.4103/0301-4738.39114subject
Has Abstractpub_date
2008-03-01 00:00:00pages
109-14issue
2eissn
0301-4738issn
1998-3689journal_volume
56pub_type
杂志文章abstract::We report ankyloblepharon filiforme adnatum (AFA) along with associated skin lesions in a 7-day-old child from South India. It could be a variant of the well described ankyloblepharon-ectodermal defects-cleft lip and palate syndrome also called Hay-Wells syndrome wherein AFA, skin lesions, and clefting are characteris...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.181741
更新日期:2016-03-01 00:00:00
abstract::Many of the causes of childhood blindness are avoidable, being either preventable or treatable. Retinopathy of prematurity (ROP) remains one of the most preventable causes of childhood blindness worldwide. Currently, India is facing the third epidemic of ROP. In India, the health system involving the mother and child ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.4103/ijo.IJO_700_18
更新日期:2019-06-01 00:00:00
abstract::Ocular dirofilariasis mostly presents as a subconjunctival or eyelid lesion. Intraocular dirofilarial infestation is rare. We report a case of a young woman who was accidentally detected to have a live motile worm in the anterior segment in one eye and a cystic lesion on the optic disc in the other eye. To our knowled...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.116252
更新日期:2014-03-01 00:00:00
abstract:Purpose:The purpose of this prospective experimental study was to evaluate the safety/toxicity of α4β1 integrin blockade in rabbit retina using its monoclonal antibody (Natalizumab). Methods:Twelve New Zealand albino rabbits were divided into three groups (n = 4). Unilateral intravitreal injections of three different ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_425_18
更新日期:2018-10-01 00:00:00
abstract:PURPOSE:To image trabeculectomy blebs using anterior segment optical coherence tomography (AS-OCT), and to correlate the bleb morphologic features at one month postoperatively with bleb function at six months. MATERIALS AND METHODS:This prospective, observational study included 56 eyes undergoing trabeculectomy with M...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.136227
更新日期:2014-06-01 00:00:00
abstract::A retrospective review of 154 trabeculectomies with releasable sutures was performed to assess the effect of suture release on intraocular pressure (IOP) at various postoperative periods. Release of the suture was necessary in 38% of cases. The immediate reduction in IOP was significant (p < 0.01) when the suture was ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1997-03-01 00:00:00
abstract:PURPOSE:To compare modified needle drainage (MND) with conventional drainage (CD) of subretinal fluid (SRF) as described by Schepens in surgery for primary rhegmatogenous retinal detachment. METHODS:Prospective randomised clinical trial of 80 patients undergoing scleral buckling with subretinal fluid drainage for prim...
journal_title:Indian journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2004-09-01 00:00:00
abstract::Corneoscleral cysts are a rare entity. We report a case of spontaneous corneoscleral hematic cyst, which was treated by cyst excision and lamellar corneal patch graft. No recurrence of cyst was noticed during the 6 years of followup. ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.25834
更新日期:2006-06-01 00:00:00
abstract::Thirty-five coagulase negative Staphylococcus (CoNS) cultured from corneal ulcer were speciated and antibiotic sensitivity tested. S epidermidis was the commonest isolate and it was sensitive to ampicillin and vancomycin. ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.15288
更新日期:2005-03-01 00:00:00
abstract::Silicone oil adherence to silicone IOLs after silicone oil removal is a known complication in pseudophakic patients. Droplet removal is difficult and may require IOL exchange. We describe two cases in which silicone oil droplets were observed early in the postoperative period in PMMA pseudophakic eyes and disappeared ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2003-06-01 00:00:00
abstract::Toric intraocular lenses (IOLs) are the procedure of choice to correct corneal astigmatism of 1 D or more in cases undergoing cataract surgery. Comprehensive literature search was performed in MEDLINE using "toric intraocular lenses," "astigmatism," and "cataract surgery" as keywords. The outcomes after toric IOL impl...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.4103/ijo.IJO_810_17
更新日期:2017-12-01 00:00:00
abstract:Purpose:To evaluate the effect of cyanidin-3-glucoside (C3G) in oxygen-induced retinopathy (OIR) mouse model. Methods:In this experimental study, 10 C57BL / 6J type mice exposed to room air comprised two control groups (n = 5 each; a negative control and a group receiving intravitreal sterile dimethyl sulfoxide [IVS D...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_166_18
更新日期:2019-06-01 00:00:00
abstract::Thirty-three eyes of 33 patients were prospectively evaluated to study the short term efficacy, safety, and overall surgical outcome of initial trabeculectomy for primary glaucomas with adjunctive intraoperative or postoperative 5-Fluorouracil (5-FU) use. Twelve eyes serving as controls underwent trabeculectomy withou...
journal_title:Indian journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1997-09-01 00:00:00
abstract::Calcinosis cutis is a rare metabolic disorder characterized by cutaneous and subcutaneous deposition of insoluble calcium salts. Ocular adnexal involvement is uncommon but mostly seen in males and in the upper eyelid. Solitary lesions are more common than multiple. The treatment of choice is excision biopsy. Histopath...
journal_title:Indian journal of ophthalmology
pub_type:
doi:10.4103/ijo.IJO_1185_17
更新日期:2018-05-01 00:00:00
abstract::To describe a smartphone-based telemedicine tool for monitoring of corneal ulcer size during the corona pandemic, a simple "U"-shaped tool was constructed using three Schirmer's strips that were provided to the patients with small to medium-sized corneal ulcers. The patient and the attendant were trained to use this s...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_1560_20
更新日期:2020-10-01 00:00:00
abstract::We describe a case of neurotrophic keratitis in association with dihydroxypyrimidine dehydrogenase (DHPD) deficiency. Ocular manifestations in patients with DHPD are rare and neurotrophic keratitis has never been reported before. A six-year-old boy who was a known case of DHPD deficiency and born of a consanguineous m...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.41422
更新日期:2008-07-01 00:00:00
abstract::The undisputed long term solution to prevent nutritional blindness lies in changing the dietary habits of a given population through nutritional education, nutritional supplementation, and nutritional rehabilitation. Before such strategies can be successfully implemented, it becomes necessary to study the existing die...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1992-10-01 00:00:00
abstract::A 10-year-old girl presented to us with inferonasally displaced, non-axial proptosis of oculus dexter (OD), with ipsilateral, painless massive cervical lymphadenopathy of ten weeks duration. After a detailed hematological work-up and imaging, the histological evidence obtained on cervical lymph node biopsy established...
journal_title:Indian journal of ophthalmology
pub_type:
doi:10.4103/ijo.IJO_1596_18
更新日期:2019-07-01 00:00:00
abstract::In this report we describe nongranulomatous uveitis followed by bilateral retinal vasculitis and much later by the loss of accommodation as initial presentations of demyelinating disease in a 42-year-old female with no other neurologic manifestations. The absence of demyelinating plaques in the initial magneric resona...
journal_title:Indian journal of ophthalmology
pub_type:
doi:10.4103/ijo.IJO_2017_19
更新日期:2020-09-01 00:00:00
abstract::A 30-year-old insomniac, an off-label user of quetiapine, presented with blurring of central vision, eventually diagnosed as central serous chorioretinopathy. A potential association was suspected based on the drug's actions on the autonomic nervous system. He showed improvement on drug withdrawal; then he unwittingly...
journal_title:Indian journal of ophthalmology
pub_type:
doi:10.4103/ijo.IJO_929_18
更新日期:2019-02-01 00:00:00
abstract::We report a case of ocular tuberculosis (TB) which initially presented with disc edema and was mistaken for optic neuritis. With no definite pathology being identified, the patient was treated on the lines of optic neuritis with intravenous (IV) steroid with beneficial effect. Ocular TB was suspected when he presented...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.154405
更新日期:2015-02-01 00:00:00
abstract:PURPOSE:The effect of hypothyroidism on the choroidal thickness (CT) was investigated in patients with subclinical hypothyroidism and overt hypothyroidism, and biochemically and clinically euthyroid patients receiving levothyroxine treatment. The patients were compared with healthy subjects. MATERIALS AND METHODS:One ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.156976
更新日期:2015-03-01 00:00:00
abstract:: ...
journal_title:Indian journal of ophthalmology
pub_type: 评论,信件
doi:10.4103/ijo.IJO_1124_18
更新日期:2019-01-01 00:00:00
abstract::One hundred and seventy adult patients and one hundred and forty-eight children with systemic malignancies were examined for ocular and/or orbital metastases. Thirty-six patients (11.3%) had intraocular and/or orbital metastasis. Twenty-nine of the 36 patients (80.5%) had orbital metastasis, five patients (13.9%) had ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract:: ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_469_18
更新日期:2018-11-01 00:00:00
abstract:Purpose:To evaluate the long-term outcomes of cataract surgery in children with uveitis. Methods:Retrospective, noncomparative review of medical records of children (≤16 years) with uveitic cataract who had undergone cataract surgery between January 2001 and December 2014 at a tertiary care center was done. The main o...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_846_18
更新日期:2019-04-01 00:00:00
abstract::IOL power prediction was performed by streak retinoscopy on the operating table after taking the previous refractive status of the patient into consideration. In 180 eyes posterior chamber lenses were implanted after determining the power of the IOL by retinoscopy on the table and selecting a suitable lens. The method...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::Globe luxation is a rare clinical event. Most of the cases are usually traumatic, although spontaneous globe luxation has also been reported. The majority of the posttraumatic cases are usually associated with the injury or fracture of the bony orbit. We report here a case of globe luxation that occurred per se withou...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.169795
更新日期:2015-08-01 00:00:00
abstract::An observational case report of electrophysiological abnormalities in a patient with anisomyopic amblyopia as a result of unilateral extensive myelinated retinal nerve fibers (MNFs) is illustrated. The electrophysiological readings revealed an abnormal pattern electroretinogram (PERG) but normal full-field electroreti...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.98724
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:The aim of this study was to assess the surgical outcomes of combined femtosecond laser-assisted cataract surgery (FLACS) with 25-gauge vitrectomy surgery. MATERIALS AND METHODS:A retrospective analysis of 45 patients who underwent combined FLACS with 25-gauge vitrectomy surgery. RESULTS:A total number of ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.191501
更新日期:2016-08-01 00:00:00