Neuroprotection in glaucoma.

Abstract:

:Glaucoma is a neurodegenerative disease characterized by loss of retinal ganglion cells and their axons. Recent evidence suggests that intraocular pressure (IOP) is only one of the many risk factors for this disease. Current treatment options for this disease have been limited to the reduction of IOP; however, it is clear now that the disease progression continues in many patients despite effective lowering of IOP. In the search for newer modalities in treating this disease, much data have emerged from experimental research the world over, suggesting various pathological processes involved in this disease and newer possible strategies to treat it. This review article looks into the current understanding of the pathophysiology of glaucoma, the importance of neuroprotection, the various possible pharmacological approaches for neuroprotection and evidence of current available medications.

journal_name

Indian J Ophthalmol

authors

Vasudevan SK,Gupta V,Crowston JG

doi

10.4103/0301-4738.73700

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

S102-13

eissn

0301-4738

issn

1998-3689

pii

IndianJOphthalmol_2011_59_7_102_73700

journal_volume

59 Suppl

pub_type

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