Abstract：
BACKGROUND:Staphylococcus epidermidis, a commensal of the conjunctival sac has been incriminated as the commonest etiological agent of bacterial keratitis. However, the pathogenic potential of this commensal organism is not clearly known. AIM:To determine any phenotypic, molecular markers of S. epidermidis pathogenicity in bacterial keratitis. MATERIALS AND METHODS:A total of 382 corneal ulcer isolates of S. epidermidis and 87 S. epidermidis isolates from healthy eyes (controls) were studied. Speciation, biotyping and antibiotic sensitivity testing were performed by conventional methods. Tube slime and adherence tests were carried out by recommended techniques. Plasmid analysis was conducted by a standard protocol. STATISTICAL ANALYSIS:Chi-square test was employed for calculations. RESULTS:Out of 382 corneal ulcer isolates (Pathogens) 284 (74.3%) belonged to biotypes I and II. Slime was detected in 164 (42.9%) of 382 pathogens vs. 21 (24.1%) of 87 controls (P<0.001). Sixty-five (39.6%) of 164 slime positive isolates were multidrug-resistant as compared to only 49 (22.4%) of 218 slime negative isolates (P<0.001). A significantly higher number i.e, 73.1% (120/164) of slime-producers possessed a 21 Kb plasmid in contrast to only 53.2% (116/218) of nonslime-producers (P<0.001). Presence of this plasmid had a statistical correlation of low significance with multidrug resistance (P=0.04). One hundred and seventy-two (45.0%) of 382 pathogens and 24 (27.6%) of the 87 controls were adherent to artificial surfaces (P=0.003) and the majority of the adherent organisms (99/172, 57.6%) were slime producers (P<0.001). CONCLUSIONS:Slime was associated with multidrug resistance in corneal ulcer isolates of S. epidermidis. The 21 Kb plasmid could determine virulence as it was responsible for slime production and adherence.
journal_name
Indian J Ophthalmoljournal_title
Indian journal of ophthalmologyauthors
Nayak N,Satpathy G,Vajpayee RB,Mrudula Sdoi
10.4103/0301-4738.29488subject
Has Abstractpub_date
2007-01-01 00:00:00pages
9-13issue
1eissn
0301-4738issn
1998-3689journal_volume
55pub_type
杂志文章abstract：Purpose:Refractory or recurrent vitreous seeds account for a large proportion of failure of eye salvage in retinoblastoma. The purpose of this study is to evaluate the efficacy of periocular topotecan (POT) in the management of vitreous seeds in retinoblastoma. Methods:Retrospective, interventional study of patients w...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_737_18
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abstract：: ...
journal_title：Indian journal of ophthalmology
pub_type： 评论
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abstract：:One hundred and seventy adult patients and one hundred and forty-eight children with systemic malignancies were examined for ocular and/or orbital metastases. Thirty-six patients (11.3%) had intraocular and/or orbital metastasis. Twenty-nine of the 36 patients (80.5%) had orbital metastasis, five patients (13.9%) had ...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
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更新日期：1989-04-01 00:00:00
abstract：Purpose:To evaluate the frequency and the association of Thrombospondin 1 (THBS1) gene single nucleotide polymorphisms (SNPs) in Asian Indian patients with optical full thickness corneal grafting surgery. Methods:Prospective case-control analysis of optical penetrating keratoplasty patients with and without immune rej...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_552_19
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.60090
更新日期：2010-03-01 00:00:00
abstract：: ...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_941_18
更新日期：2019-01-01 00:00:00
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journal_title：Indian journal of ophthalmology
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doi：10.4103/ijo.IJO_736_18
更新日期：2019-01-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_295_18
更新日期：2018-08-01 00:00:00
abstract：:Silicone oil adherence to silicone IOLs after silicone oil removal is a known complication in pseudophakic patients. Droplet removal is difficult and may require IOL exchange. We describe two cases in which silicone oil droplets were observed early in the postoperative period in PMMA pseudophakic eyes and disappeared ...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：2003-06-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_473_17
更新日期：2017-11-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.121083
更新日期：2013-10-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.179715
更新日期：2016-02-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_445_18
更新日期：2019-01-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.25834
更新日期：2006-06-01 00:00:00
abstract：:Two three-piece hydrophobic acrylic intraocular lenses (IOLs) were explanted from two patients at 7 and 9 years, respectively, after implantation, because of poor fundus visualisation and/or a clinically significant decrease in visual acuity related to their opacified IOLs. In addition to light microscopy, scanning el...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.136262
更新日期：2014-06-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.195603
更新日期：2016-11-01 00:00:00
abstract：:We describe a surgical technique for the correction of isolated congenital lenticular coloboma associated with high corneal astigmatism. Transscleral fixation of the capsular bag with a single eyelet Cionni capsular tension ring was followed by in-the-bag implantation of a toric intraocular lens (IOL). This lead to co...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_1026_17
更新日期：2018-04-01 00:00:00
abstract：:Defects in renewal and repair of ocular surface as a result of limbal stem cell deficiency are now known to cause varying ocular surface morbidity including persistent photophobia, repeated and persistent surface breakdown and overt conjunctivalisation of the cornea. Ocular conditions with abnormalities of ocular surf...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
doi：
更新日期：2000-06-01 00:00:00
abstract：:Magnetic resonance imaging (MRI) and computerized tomography (CT) have added a new dimension in the diagnosis and management of ocular and orbital diseases. Although CT is more widely used, MRI is the modality of choice in select conditions and can be complimentary to CT in certain situations. The diagnostic yield is ...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.4103/0301-4738.98711
更新日期：2012-07-01 00:00:00
abstract：:The prevalence of youth-onset diabetes, both type 1 diabetes (T1D) and young-onset type 2 diabetes (YT2D) are gradually increasing in India. Early and repetitive screening for diabetic retinopathy (DR) is essential to provide timely management, and thereby prevent visual impairment due to the silent sight-threatening ...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_1851_19
更新日期：2020-02-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_472_18
更新日期：2018-11-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.4103/ijo.IJO_2036_19
更新日期：2019-12-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.171505
更新日期：2015-10-01 00:00:00
abstract：:We evaluated the effectiveness of diode laser trans-scleral cyclophotocoagulation (TSCPC) on intraocular pressure (IOP) in nine patients having raised IOP following use of silicone oil (SO) for retinal detachment (RD) surgery in a retrospective observational case series. Diode laser TSCPC was applied at a power settin...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.73730
更新日期：2011-01-01 00:00:00
abstract：:Pneumatic retinopexy (PR) is an alternative to scleral buckling for the surgical repair of selected retinal detachments. A gas bubble is injected into the vitreous cavity, and the patient is positioned so that the bubble closes the retinal break (s), allowing absorption of the subretinal fluid. Cryotherapy or laser ph...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
doi：
更新日期：1996-09-01 00:00:00
abstract：:This report describes a case of unilateral spontaneous vitreous haemorrhage associated with congenital retinal arterial loops. ...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1999-09-01 00:00:00
abstract：Purpose:Perioperative inadvertent hypothermia (PIH) is the decrease in core temperature below 36°C. We aimed to assess whether PIH develops in patients operated under local anesthesia (ULA) for vitreoretinal surgery in the operating room and investigate active warming efficacy. Methods:Seventy-two patients were divide...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_227_20
更新日期：2021-02-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type：
doi：10.4103/ijo.IJO_429_17
更新日期：2018-01-01 00:00:00
