Abstract：
Purpose:To analyse topographic and tomographic changes in fellow eyes of unilateral keratoconus patients by comparing them with normal eyes. Methods:This five-year retrospective observational comparative case study included 15 advanced keratoconus eyes of unilateral keratoconus (KCN group), 15 normal fellow eyes of unilateral keratoconus (Fellow eye group) and 34 eyes of normal refractive surgery candidates (Normal group). Topographic and tomographic data, data from enhanced elevation maps, and keratoconus indices were measured in all study eyes using Pentacam. Receiver operating characteristic (ROC) curves were used to evaluate the area under the curve (AUC), sensitivity and specificity of each parameter and identify cut-off points in discriminating between the fellow and normal eyes. Results:Corneal thickness at the apex (CTA, P = 0.001) and at the thinnest point (CTT, P < 0.001), corneal volume (CV, P = 0.007), Belin/Ambrosio Enhanced Ectasia Display (BAD) - thinnest point (Dt, P = 0.002) and thinnest point displacement (Da, P = 0.002) were significantly lower in the fellow group compared to eyes of normal subjects. On ROC curve analysis, the most efficient distinguishing indices between the fellow group and normal controls were BAD - overall D value (AUC = 0.859), Dt (AUC =0.827), Da (AUC = 0.789) followed by pachymetric progression index maximum (AUC = 0.741). Conclusion:BAD-D value and pachymetric progression index could be useful in detecting the earliest form of subclinical keratoconus. However, every single parameter alone is not enough to detect early changes; a combination of different data is required to distinguish subclinical keratoconus.
journal_name
Indian J Ophthalmoljournal_title
Indian journal of ophthalmologyauthors
Thulasidas M,Teotia Pdoi
10.4103/ijo.IJO_2129_19subject
Has Abstractpub_date
2020-11-01 00:00:00pages
2415-2420issue
11eissn
0301-4738issn
1998-3689pii
IndianJOphthalmol_2020_68_11_2415_299045journal_volume
68pub_type
杂志文章abstract：:Surgery in the management of uveitis can be divided based on indication: either for therapeutic or can be for diagnostic purposes or to manage complications. The commonest indications include: Visual rehabilitation: surgery for removal of cataract, band keratopathy, corneal scars, pupillary membranes, removal of dense...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
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journal_title：Indian journal of ophthalmology
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abstract：: ...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_773_18
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:The thesis is an integral part of postgraduate medical education in India. Publication of the results of the thesis in an indexed journal is desirable; it validates the research and makes results available to researchers worldwide. AIMS:To determine publication rates in indexed journals, of works derived fr...
journal_title：Indian journal of ophthalmology
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abstract：:The cost of technology is high in ophthalmology but given the increasingly competitive environment and the social demand, there is a pressure to progressively lower the costs to the consumer. To keep costs down there is a tendency to do as many surgeries as possible in an assembly line fashion both in hospitals as wel...
journal_title：Indian journal of ophthalmology
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journal_title：Indian journal of ophthalmology
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doi：10.4103/0301-4738.154405
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
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更新日期：1991-10-01 00:00:00
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journal_title：Indian journal of ophthalmology
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journal_title：Indian journal of ophthalmology
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type：
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更新日期：2018-11-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
doi：
更新日期：1990-07-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.73691
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
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更新日期：2017-11-01 00:00:00
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pub_type： 杂志文章
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：2002-03-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
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pub_type： 杂志文章,随机对照试验
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
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journal_title：Indian journal of ophthalmology
pub_type： 评论,信件
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：: ...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_940_18
更新日期：2019-01-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
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journal_title：Indian journal of ophthalmology
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更新日期：2019-03-01 00:00:00
