Abstract：
Purpose:To evaluate the long-term safety and efficacy of the intravitreal dexamethasone implant in the treatment of diabetic macular edema (DME) as initial therapy. Methods:A hospital-based prospective, non-comparative case study of recently detected DME patients was conducted between July 2016 and December 2017, in which30 eyes of 30 patients were studied. Presenting vision, age, gender, duration of diabetes, general and ocular examination, intraocular pressure, indirect ophthalmoscopy, fundus fluorescein angiography, optical coherence tomography (OCT), and blood sugar levels were noted. Patients with increased central macular thickness (CMT) received an intravitreal dexamethasone implant as initial therapy. All were followed up at 1 week, 1 month, 3 months, 6 months, and 1 year, and the findings were recorded and analyzed using SPSS software. Results:30 eyes of 30 patients were studied which included 22 males and 8 females. The mean age of presentation was 58.7 ± 4.45 years. The mean decrease in CMT following intravitreal dexamethasone was 269.27 ± 112.002, 253.5 ± 108.294, and 286.73 ± 143.395 μm at the end of 3, 6, and 12 months, respectively, and the mean improvement in visual acuity (VA) was 2.27 ± 1.70 lines at 3 months, 2.27 ± 1.83 lines at 6 months, and 1.17 ± 2.00 lines at 12 months. Out of 30 cases, 4 had persistent DME and 6 had recurrence of DME at completion of 1 year of follow-up. Conclusion:Intravitreal dexamethasone as initial therapy in the treatment of DME is both safe and efficacious in the reduction of CMT and improvement of vision and can be considered as primary therapy for DME.
journal_name
Indian J Ophthalmoljournal_title
Indian journal of ophthalmologyauthors
Mahapatra SK,Kumari Sdoi
10.4103/ijo.IJO_620_19subject
Has Abstractpub_date
2020-03-01 00:00:00pages
490-493issue
3eissn
0301-4738issn
1998-3689pii
IndianJOphthalmol_2020_68_3_490_278368journal_volume
68pub_type
杂志文章abstract：:Dengue fever, a mosquito-borne disease commonly found in the tropics, is one of the most prevalent forms of Flavivirus infection in humans. Symptomatically, it is characterized by fever, arthralgia, headache, and rash. Ophthalmic manifestations can involve both the anterior and posterior segment. Panophthalmitis is ra...
journal_title：Indian journal of ophthalmology
pub_type：
doi：10.4103/ijo.IJO_113_18
更新日期：2018-07-01 00:00:00
abstract：:A 10-year-old girl presented to us with inferonasally displaced, non-axial proptosis of oculus dexter (OD), with ipsilateral, painless massive cervical lymphadenopathy of ten weeks duration. After a detailed hematological work-up and imaging, the histological evidence obtained on cervical lymph node biopsy established...
journal_title：Indian journal of ophthalmology
pub_type：
doi：10.4103/ijo.IJO_1596_18
更新日期：2019-07-01 00:00:00
abstract：:We report a case of 18-year-old male who has undergone phacoemulsification with implantation of toric IOL (AcrySof IQ SN6AT9) after fixation of lens capsule with Cionni's capsular tension ring (CTR) for subluxated traumatic cataract with high astigmatism after deep anterior lamellar keratoplasty (DALK). He underwent r...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.138294
更新日期：2014-07-01 00:00:00
abstract：:We report an unusual case of angle closure glaucoma in a 78-year-old highly myopic female patient. The patient did not show any preoperative signs of subluxation of lens. However, the capsular bag was noted to be unstable during surgery. The patient was managed with phacoemulsification of lens using a novel method of ...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.27953
更新日期：2006-12-01 00:00:00
abstract：:A 60-year-old man presented with sudden-onset proptosis of the left eye and intermittent diplopia of 2 months duration. Ophthalmic examination revealed bilateral eyelid retraction, left eye proptosis and a firm, non-tender mass (2 cm × 1.5 cm) in left supero-medial orbit with restricted extraocular movements. Contrast...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_1699_18
更新日期：2019-08-01 00:00:00
abstract：Purpose:To compare different macular thickness parameters and peripapillary retinal nerve fiber layer (RNFL) thickness between recently diagnosed cases of multiple sclerosis (MS) without optic neuropathy (ON) and healthy individuals. Methods:This cross-sectional study was performed between June 2014 and June 2015. All...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_1378_18
更新日期：2019-05-01 00:00:00
abstract：:Advancements in physics, computers, and imaging science in the last century have seen neuro-imaging evolving from a plain X-ray to computed tomography, magnetic resonance imaging scans, noninvasive angiography, and special sequences such as fat suppression, fluid attenuation recovery and diffusion-weighted imaging. A ...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.77015
更新日期：2011-03-01 00:00:00
abstract：:Tumours arising in the sweat glands of the eyelids are rare. A case of Eccrine Acrospiroma, otherwise, called clear cell hidradenoma, a benign sweat gland tumour of the lid in a female aged 70 years is being reported because of its rarity. ...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1990-10-01 00:00:00
abstract：:We report the clinical details and imaging findings for a case of nondecussating retinal-fugal fiber syndrome or isolated achiasma in a 4-year-old female child. Findings included the isolated absence of optic chiasm with unremarkable rest of the optic pathway and midline structures in a child presenting clinically wit...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.171970
更新日期：2015-11-01 00:00:00
abstract：: ...
journal_title：Indian journal of ophthalmology
pub_type： 评论,信件
doi：10.4103/ijo.IJO_1415_18
更新日期：2018-11-01 00:00:00
abstract：:This study was conducted to determine awareness and practices relating to diabetic retinopathy among non-medical persons in a south Indian population. In this population-based cross-sectional study, trained social workers conducted face-to-face interviews using a semi-structured questionnaire with 200 randomly selecte...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：2004-09-01 00:00:00
abstract：Purpose:Trachoma is the leading infectious cause of blindness in the world. It is caused by conjunctival infection with the bacterium Chlamydia trachomatis. The objective of this study was to determine the prevalence and risk factors of active trachoma among primary school children in Amhara region, Ethiopia. Methods:...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_143_19
更新日期：2020-05-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
doi：
更新日期：1996-06-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_157_17
更新日期：2017-11-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.16178
更新日期：2005-06-01 00:00:00
abstract：Purpose:To evaluate the feasibility and safety of heads-up three-dimensional (3D) vision system for phacoemulsification and intraocular lens (IOL) implantation surgery. Methods:In this prospective, randomized controlled study, 20 eyes with age-related cataract received phacoemulsification and IOL implantation and were...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.4103/ijo.IJO_1012_18
更新日期：2019-03-01 00:00:00
abstract：PURPOSE:To correlate fixation stability and retinal sensitivity measured by liquid crystal display (LCD) microperimetry to visual acuity in eyes with macular pathology. DESIGN:Retrospective chart review METHODS:The cohort included 26 eyes of 26 patients, divided into two groups according to visual acuity (Group 1 eye...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：2004-12-01 00:00:00
abstract：:Transepithelial photorefractive keratectomy (tPRK) promotes faster re-epithelialization which in turn can reduce the risk of infectious keratitis in the postoperative period. We present a case of a 22-year-old man with infectious keratitis in his left eye 8 days after an uneventful bilateral tPRK. A 2 mm × 5 mm anteri...
journal_title：Indian journal of ophthalmology
pub_type：
doi：10.4103/ijo.IJO_1730_20
更新日期：2020-12-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.43383
更新日期：2008-11-01 00:00:00
abstract：Purpose:To compare the outcomes of two techniques, for preparation of microkeratome-assisted ultrathin grafts for Descemet's stripping automated endothelial keratoplasty (DSAEK). Methods:The study involved 20 eyes of 20 patients with pseudophakic bullous keratopathy, randomized into two groups. Group 1 eyes underwent ...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.4103/ijo.IJO_1660_18
更新日期：2019-08-01 00:00:00
abstract：Purpose:To analyze and report outcomes of microincision vitrectomy surgery (MIVS) for Stage 4 and 5 retinopathy of prematurity (ROP). Methods:Medical records of 202 eyes of 129 premature children undergoing MIVS for Stage 4/Stage 5 ROP between January 2012 and April 2015 were evaluated. The primary outcome measure was...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_1030_17
更新日期：2019-06-01 00:00:00
abstract：PURPOSE:To ascertain if the polymerization reaction also contributes additionally to the antibacterial effects of two commonly used cyanoacrylate tissue adhesives. MATERIALS AND METHODS:Fresh liquid ethyl-cyanoacrylate (EC) and N-butyl-cyanoacrylate (BC) adhesives were applied onto 6-mm sterile filter paper discs. In ...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.55065
更新日期：2009-09-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_819_17
更新日期：2018-03-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：2000-03-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type：
doi：10.4103/ijo.IJO_2281_19
更新日期：2020-08-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type：
doi：10.4103/ijo.IJO_196_17
更新日期：2018-02-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.169795
更新日期：2015-08-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_1399_20
更新日期：2020-12-01 00:00:00
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journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1990-10-01 00:00:00
abstract：:Defects in renewal and repair of ocular surface as a result of limbal stem cell deficiency are now known to cause varying ocular surface morbidity including persistent photophobia, repeated and persistent surface breakdown and overt conjunctivalisation of the cornea. Ocular conditions with abnormalities of ocular surf...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
doi：
更新日期：2000-06-01 00:00:00
