Abstract:
Purpose:Radial keratoneuritis (RK) is a common feature of Acanthamoeba keratitis (AK). In vivo confocal microscopy (IVCM) is noninvasive and provides real-time images for the diagnosis of corneal diseases by allowing the visualization of corneal structures and morphologies of living organisms at the cellular level. Images of AK with RK obtained using commercial white light IVCM devices have not been frequently evaluated. In the present study, a white light IVCM device was used to evaluate the corneal findings and describe spatial changes in the corneal nerves at different depths in cases of early-stage AK with RK. Methods:In this retrospective, observational study, white light IVCM images focused on RK were evaluated for Acanthamoeba cysts/trophozoites, corneal deposits, and altered corneal nerves, with special emphasis on three-dimensional spatial changes in the corneal nerves at different depths. Results:Seventeen eyes of 17 patients exhibiting early-stage AK with RK were included in the study. Acanthamoeba cysts/trophozoites were observed in the corneal epithelium of 13 eyes and stroma of 7 eyes. Alterations in the corneal nerve morphology and density were observed from the basal epithelial layer to the stromal layer in 12 eyes. Acanthamoeba trophozoites were attached to the corneal stromal nerves in five eyes. Conclusion:These findings suggest that white light IVCM can identify consistent corneal findings, particularly spatial changes in the corneal nerves, in cases of early-stage AK with RK.
journal_name
Indian J Ophthalmoljournal_title
Indian journal of ophthalmologyauthors
Hung KC,Lu CJ,Liu HY,Hou YC,Wang IJ,Hu FR,Chen WLdoi
10.4103/ijo.IJO_1313_19subject
Has Abstractpub_date
2020-06-01 00:00:00pages
1061-1066issue
6eissn
0301-4738issn
1998-3689pii
IndianJOphthalmol_2020_68_6_1061_284771journal_volume
68pub_type
杂志文章abstract:Purpose:To analyze applications for blindness certificates to find causes of visual impairment (VI), handicap, and blindness in a tertiary hospital of Bihar. Methods:Applications for blindness certificates were analyzed over a two-year period. The main cause of blindness, visual handicap, and VI in these applications ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
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doi:
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
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更新日期:2001-06-01 00:00:00
abstract:: ...
journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
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journal_title:Indian journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_2008_19
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_56_19
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.30714
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,多中心研究
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journal_title:Indian journal of ophthalmology
pub_type:
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
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journal_title:Indian journal of ophthalmology
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