Abstract:
Purpose:Relaxin is a polypeptide hormone produced by the corpus luteum and the decidua in females and by the prostate in males. It has vasodilatory and antifibrotic effects. In the past, it has been reported that injection of relaxin hormone has caused a reduction in the intraocular pressure although its mechanism has not yet been fully understood and the expression of relaxin receptors has not yet been evident in the human eye. Therefore, the purpose of this current study was to examine the presence of relaxin receptors in the human eye anterior segment. Methods:This is an interventional non-randomized study. Patients with primary open-angle glaucoma who underwent trabeculectomy were recruited. During the surgery, a punch biopsy (including the cornea, sclera, trabecular meshwork, and Schlemm's canal) was taken and stained with hematoxylin-eosin, and immunohistochemistry staining for relaxin/insulin-like family peptide receptor 1 (RXFP1). Results:A positive staining was noted for RXFP1 in the inner uveal, corneoscleral, and cribriform meshwork and Schlemm's canal's endothelium. Negative staining for RXFP1 was noted in the cornea and sclera. Conclusion:RXFP1 is present in the anterior segment drainage system of the human eye. Therefore, this receptor may have an active role in regulating the outflow facility and in the reduction of intraocular pressure.
journal_name
Indian J Ophthalmoljournal_title
Indian journal of ophthalmologyauthors
Zloto O,Skaat A,Fabian ID,Rosner M,Ziv H,Leshno A,Melamed Sdoi
10.4103/ijo.IJO_2008_19subject
Has Abstractpub_date
2020-10-01 00:00:00pages
2117-2120issue
10eissn
0301-4738issn
1998-3689pii
IndianJOphthalmol_2020_68_10_2117_295689journal_volume
68pub_type
杂志文章abstract::Optical coherence tomography (OCT) was done in 20 eyes to detect causes of poor visual outcome, at least three months after successful management of endophthalmitis, which obtained clear media and best corrected visual acuity of < 20/40. Only four (20%) eyes had normal foveal contour on OCT. Eleven (55%) eyes showed t...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.31953
更新日期:2007-05-01 00:00:00
abstract:PURPOSE:To report the role of Ultrasound Biomicroscopy (UBM) as a tool in the diagnosis and management of cyclodialysis clefts. METHODS:Six eyes of 6 patients with hypotony and suspected or diagnosed cyclodialysis clefts underwent UBM evaluation. Post-treatment UBM was performed in four eyes to assess the effect of th...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1999-03-01 00:00:00
abstract:Purpose:To validate the smartphone photography as a screening tool for amblyogenic conditions in children. Methods:Children between 5 to 8 years attending eye out patient department (OPD) were photographed (by an optometrist) with a smartphone to capture their pupillary red reflexes followed by clinical examination by...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_2090_18
更新日期:2019-10-01 00:00:00
abstract::Primary localized amyloidosis of lacrimal gland is a rare occurrence. This report describes a female patient with isolated amyloidosis of the lacrimal gland. A 45-year-old Indian woman presented with a swelling over the left lacrimal gland region. Computed tomography showed uniform enlargement of the lacrimal gland. A...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.57160
更新日期:2009-11-01 00:00:00
abstract::Visual field testing is mandatory for many ophthalmic conditions including glaucoma. The current gold standard for visual field testing is automated perimetry. In this article we familiarize the reader with the components of an automated perimetry printout. We describe a systematic approach that leads to a thorough in...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2001-06-01 00:00:00
abstract:BACKGROUND:The successful lowering of the intraocular pressure after glaucoma filtration surgery depends mostly on the nature of the healing response, which is also the single most important modifiable factor. AIMS:To evaluate and compare the effectiveness of two oxidated regenerated cellulose material, Interceed and ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.39114
更新日期:2008-03-01 00:00:00
abstract::A 42-year-old man presenting with complaints of squint for last 20 years. His visual acuity was 20/400 in right eye (RE) and 20/30 in left eye (LE) with glasses. His refraction was RE -16.75/-2.5 D cycl 180 and LE was -14.5/-1.5 D cycl 180. His axial length was 31.23 mm In RE and 29.72 mm in LE. On examination we foun...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.151480
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:The purpose of this study is to evaluate the safety and benefits of immediate sequential bilateral cataract surgery. PATIENTS AND METHODS:Retrospective data analysis of patients who underwent immediate sequential bilateral phacoemulsification with foldable intraocular lens (IOL) implantation under topical anes...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_947_16
更新日期:2017-05-01 00:00:00
abstract:PURPOSE:To evaluate the epidemiological characteristics and outcomes of ocular injuries resulting from the use of firecrackers during the Diwali festival in all age groups. MATERIALS AND METHODS:A single-center, retrospective, hospital-based case series presenting with ocular trauma consequent to fireworks usage in a ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_527_16
更新日期:2017-02-01 00:00:00
abstract::Very few immunological studies in vernal catarrh have been conducted in India and abroad, but none in Himachal Pradesh in spite of its high incidence in the State. In the present study 25 patients of vernal catarrh residing at a height ranging between 1000 to 2500 meters above mean sea level have been evaluated. Their...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1992-07-01 00:00:00
abstract:PURPOSE:To report the prevalence of amblyopia risk factors in children with congenital nasolacrimal duct obstruction. METHODS:A retrospective review of records of children with the diagnosis of congenital nasolacrimal duct obstruction (NLDO), who underwent probing from January 2009 to October 2011, was done. All of th...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.190101
更新日期:2016-07-01 00:00:00
abstract:Purpose:To evaluate the effect of acute submaximal exercise on intraocular pressure (IOP) fluctuations in open-angle glaucoma (OAG) subjects using an ocular telemetry sensor (OTS, Sensimed TriggerFish®). Methods:Twelve OAG subjects aged 45-65 years with no medical limitation for exercise were included in this prospect...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_585_18
更新日期:2019-01-01 00:00:00
abstract:AIMS:To report the technique and outcomes of sutureless manual cataract extraction via a subconjunctival limbus oblique incision for mature cataracts. MATERIALS AND METHODS:This retrospective study comprised of 112 eyes of 83 patients with mature cataract who all had manual cataract extraction via a subconjunctival li...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.121135
更新日期:2014-03-01 00:00:00
abstract::One hundred and seventy adult patients and one hundred and forty-eight children with systemic malignancies were examined for ocular and/or orbital metastases. Thirty-six patients (11.3%) had intraocular and/or orbital metastasis. Twenty-nine of the 36 patients (80.5%) had orbital metastasis, five patients (13.9%) had ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::Chronic infection of the cornea by Herpes simplex virus (HSV) continues to be an important cause of unilateral blindness. Despite considerable progress in the understanding of the virus at cellular and molecular levels, the prospect of prevention still appears to be long way off. The development of non-toxic topical a...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1999-09-01 00:00:00
abstract::We evaluated the effectiveness of diode laser trans-scleral cyclophotocoagulation (TSCPC) on intraocular pressure (IOP) in nine patients having raised IOP following use of silicone oil (SO) for retinal detachment (RD) surgery in a retrospective observational case series. Diode laser TSCPC was applied at a power settin...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.73730
更新日期:2011-01-01 00:00:00
abstract:: ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_940_18
更新日期:2019-01-01 00:00:00
abstract::An unidentified nematode in the retina of an otherwise healthy young lady causing inflammation and exudation is reported. The worm was destroyed by Xenon photocoagulation, There was complete recovery and remarkable improvement in visual acuity. ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1990-10-01 00:00:00
abstract:AIM:To compare the surgical outcome of adjustable with the conventional recession in patients with horizontal comitant strabismus. PATIENTS AND METHODS:A prospective comparative nonrandomized interventional pilot study was performed on patients with horizontal comitant strabismus. Fifty-four patients (27 in each group...
journal_title:Indian journal of ophthalmology
pub_type: 临床试验,杂志文章
doi:10.4103/0301-4738.167117
更新日期:2015-07-01 00:00:00
abstract::Osseous choristoma of the choroid, also called choroidal osteoma, is a very rare and unusual form of intraocular ossification. We report a case of choroidal osteoma in a young healthy male that to the best of our knowledge is the first report from India. ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
abstract::Choroidal nodules in neurofibromatosis type-1 are common and are best imaged with near-infrared reflectance (NIR) imaging. The authors describe swept-source optical coherence tomography angiography (SSOCTA) of choroidal nodules. These nodules are seen as hyperflow areas on SSOCTA and correlate well to bright patches o...
journal_title:Indian journal of ophthalmology
pub_type:
doi:10.4103/ijo.IJO_1095_17
更新日期:2018-04-01 00:00:00
abstract::We describe a vertical lid split orbitotomy approach to perform optic nerve sheath fenestration which was done in a patient with idiopathic intracranial hypertension. A vertical lid split incision was used to enter the superomedial orbit and approach the optic nerve sheath. This approach resulted in a successful nerve...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.53057
更新日期:2009-07-01 00:00:00
abstract:Purpose:To evaluate the feasibility and safety of heads-up three-dimensional (3D) vision system for phacoemulsification and intraocular lens (IOL) implantation surgery. Methods:In this prospective, randomized controlled study, 20 eyes with age-related cataract received phacoemulsification and IOL implantation and were...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.4103/ijo.IJO_1012_18
更新日期:2019-03-01 00:00:00
abstract::Jampolsky's approach to the diagnosis of strabismus is simple. Certain tests are to be performed in sequence to determine 1) the presence of fusion in the habitual head position under normal viewing conditions and in the primary position at near and distance; 2) the presence and characteristics of fusion vergences and...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1996-06-01 00:00:00
abstract:: ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_773_18
更新日期:2019-02-01 00:00:00
abstract:Purpose:External dacryocystorhinostomy (DCR) surgeries are cost-effective with excellent success rates. The present study was designed to compare the safety and efficacy of conventional external DCR versus external DCR using Pawar silicone implant in chronic dacryocystitis. Methods:This is a prospective, comparative, ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_1889_18
更新日期:2019-07-01 00:00:00
abstract:: ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_469_18
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:Microsporidial stromal keratitis poses several diagnostic challenges. Patients may present with corneal ulceration, marked stromal thinning, or even as a quite corneal scar. The presentation of microsporidial stromal keratitis commonly mimics viral keratitis. Microbiology scrapings are usually helpful; howev...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_761_15
更新日期:2017-04-01 00:00:00
abstract::We report a case series of patients who developed post-laser-assisted in situ keratomileusis (LASIK) ectasia or had a progression of keractesia during pregnancy. We reviewed the medical records of 12 patients (20 eyes) who had reported deterioration of vision during their pregnancy and were diagnosed with keractesia. ...
journal_title:Indian journal of ophthalmology
pub_type:
doi:10.4103/ijo.IJO_1508_20
更新日期:2020-12-01 00:00:00
abstract:Purpose:The effectiveness of Accredited Social Health Activists (ASHAs) with and without monetary incentive in uptake of diabetic retinopathy (DR) screening at community health center (CHC) was compared in South Gujarat, India. Methods:In this non-randomized controlled trial, ASHAs were incentivized to refer people wi...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_2118_19
更新日期:2020-02-01 00:00:00