Abstract：
AIM:To study the indications, risk factors, postoperative course, and long-term survival of corneal transplants done for optical purposes. DESIGN:Retrospective case series. MATERIALS AND METHODS:Data were obtained by reviewing the records of 181 patients operated at our institute (H.V. Desai Eye Hospital) between October 2005 and October 2007 for optical penetrating keratoplasty. Patients with less than one year of follow up, pediatric cases, therapeutic, tectonic, and lamellar keratoplasties were excluded. Kaplan Meier survival analysis was used to calculate median survival time of grafts and to see correlation between nine variables viz. age, gender, corneal vascularization, previous failed grafts, previous Herpes Simplex keratitis, post-perforation corneal scars, donor tissue quality, graft size, type of surgery and follow-up. These variables were also used for univariate and multivariate analysis using Cox Proportional Hazard Regression Modeling. RESULTS:Median survival of the cohort was 27 months (95% confidence interval: 20.47-33.52). One- and two-year survival rates were 65% and 52.5%, respectively. Median survival was significantly lower in poor prognosis cases (14 months) than good prognosis cases (27 months, P = 0.0405). Graft survival was lower in vascularized corneas (18.55 months, P = 0.030) and in post-perforation corneal scars (17.96 months, P = 0.09, borderline significance). Multivariate analysis showed that the same factors were predictive of graft failure. CONCLUSION:Long-term survival of grafts at our center is different from centers in western world. More high-risk cases, paucity of excellent quality donor corneas, and differences in patient profile could be the contributory factors.
journal_name
Indian J Ophthalmoljournal_title
Indian journal of ophthalmologyauthors
Joshi SA,Jagdale SS,More PD,Deshpande Mdoi
10.4103/0301-4738.91337subject
Has Abstractpub_date
2012-01-01 00:00:00pages
15-21issue
1eissn
0301-4738issn
1998-3689pii
IndianJOphthalmol_2012_60_1_15_91337journal_volume
60pub_type
杂志文章abstract：:A prospective randomized clinical trial was carried out to compare the intercapsular or the endocapsular technique of IOL insertion and conventional posterior chamber IOL insertion after can opener capsulotomy. Age and sex matched groups of 76 patients each underwent surgery by the two techniques. The corneal and the ...
journal_title：Indian journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1991-04-01 00:00:00
abstract：Purpose:The purpose of the study is to report the outcomes of simultaneous cataract extraction (CE) and a new nonvalved glaucoma drainage device (GDD), Aurolab Aqueous Drainage Implant (AADI), in eyes with cataract and refractory glaucoma. Methods:This was a non-comparative, interventional, retrospective study. Consec...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_195_18
更新日期：2018-09-01 00:00:00
abstract：PURPOSE:Resections and plications tighten recti although the latter are less traumatic, potentially reversible, quicker, and vascularity preserving. To compare inflammation, scarring, and alignment in horizontal strabismus, operated uniocularly by either resections or plications (with recessions): recession and resecti...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.4103/ijo.IJO_968_16
更新日期：2017-09-01 00:00:00
abstract：:IOL power prediction was performed by streak retinoscopy on the operating table after taking the previous refractive status of the patient into consideration. In 180 eyes posterior chamber lenses were implanted after determining the power of the IOL by retinoscopy on the table and selecting a suitable lens. The method...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：Purpose:To comparatively analyze the structural and functional tests used in the diagnosis and follow-up of glaucoma. Methods:Eighty eyes of 40 patients with primary open angle glaucoma (POAG) and 46 eyes of 23 healthy individuals were included in the study. Transient pattern electroretinography (PERG), steady-state P...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_921_19
更新日期：2020-05-01 00:00:00
abstract：:In this report we describe nongranulomatous uveitis followed by bilateral retinal vasculitis and much later by the loss of accommodation as initial presentations of demyelinating disease in a 42-year-old female with no other neurologic manifestations. The absence of demyelinating plaques in the initial magneric resona...
journal_title：Indian journal of ophthalmology
pub_type：
doi：10.4103/ijo.IJO_2017_19
更新日期：2020-09-01 00:00:00
abstract：:110 cases of keratomycosis were treated with itraconazole administered either orally or topically or by both routes. Excellent or moderate response was obtained in 69 percent of the patients. Ulcers due to Aspergillus and dematiaceous fungi and non-sevee ulcers responded better than did severe ulcers and ulcers due to...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：BACKGROUND:Platelets are an elective site for oxidative stress owing to their high content of polyunsaturated fatty acid. Increased lipid peroxidation and elevated platelet thiobarbituric acid-reacting substances (TBARS) signal oxidative stress. This possibly leads to retinal neovascularization in Eales' disease. METH...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：2000-12-01 00:00:00
abstract：:Xeroderma pigmentosum (XP) is an autosomal recessive disease with ophthalmic, dermatologic, and neurologic manifestations. Ophthalmological changes are described in up to 100% of XP patients. We report a young XP patient that presented with bilateral conjunctival masses. She was treated by surgical excision with suppl...
journal_title：Indian journal of ophthalmology
pub_type：
doi：10.4103/ijo.IJO_1106_18
更新日期：2019-07-01 00:00:00
abstract：:We report a case of intraconal grease gun injury along with traumatic optic neuropathy in a 20-year-old male. He presented with dimness of vision and proptosis of the left eye (LE) following an accidental injury at work place. The computer tomography of orbit revealed hypodense grease orbit. Cream colored grease was c...
journal_title：Indian journal of ophthalmology
pub_type：
doi：10.4103/ijo.IJO_2281_19
更新日期：2020-08-01 00:00:00
abstract：:Endoilluminator-assisted scleral buckling combines the advantages of scleral buckling for its external approach and pars plana vitrectomy for its better visual visualization in the management of retinal detachment (RD). It has recently been proven to be safe and efficacious in simple cases. This report discusses succe...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.195603
更新日期：2016-11-01 00:00:00
abstract：Purpose:To use the extent of retinal immaturity at the first visit to predict progression to any stage and treatment-requiring retinopathy of prematurity (ROP). Methods:Retrospective, multicenter, nonrandomized, observational, clinical, validation study. In all, 601 Asian Indian preterm infants born < 2000 g and/or < ...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.4103/ijo.IJO_469_19
更新日期：2019-06-01 00:00:00
abstract：:In the presence of proliferations anteriorly, adequate excision of the vitreous base is essential. To enable a good vitreous base excision, removal of lens often becomes necessary as it may be damaged while attempting to remove peripheral vitreous. To avoid damage or the need to remove the crystalline lens we have use...
journal_title：Indian journal of ophthalmology
pub_type： 临床试验,杂志文章
doi：
更新日期：1998-06-01 00:00:00
abstract：:Several decades ago, penetrating keratoplasty was a challenge to corneal surgeons. Constant effort by the corneal surgeon to improve the outcomes as well as utilization of the available resources has led to a revolutionary change in the field of keratoplasty. All these efforts have led to the evolution of techniques t...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.4103/ijo.IJO_582_17
更新日期：2017-08-01 00:00:00
abstract：:Chronic infection of the cornea by Herpes simplex virus (HSV) continues to be an important cause of unilateral blindness. Despite considerable progress in the understanding of the virus at cellular and molecular levels, the prospect of prevention still appears to be long way off. The development of non-toxic topical a...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
doi：
更新日期：1999-09-01 00:00:00
abstract：:For the purpose of this symposium, the term "keratitis" implies suppurative nonviral and viral keratitis. Corneal ulcers have been described in ancient literature. But even today, despite the availability of a wide range of newer antimicrobials and new diagnostic techniques, infective keratitis continues to pose a dia...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.40358
更新日期：2008-05-01 00:00:00
abstract：OBJECTIVE:The objective was to study the incidence and risk factors for an early rise in intraocular pressure (IOP) following pars plana vitrectomy (PPV) for proliferative diabetic retinopathy (PDR) and to correlate its impact on visual outcome. MATERIALS AND METHODS:This was a longitudinal prospective study. IOP and ...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.73724
更新日期：2011-01-01 00:00:00
abstract：:"There are many classifications of xerophthalmia in existence. In the present study all these classification have been exhaustively reviewed. Many objections to previous classifications have been raised following experiences with these classifications for over six years. Based on these objections a self explanatory, e...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1991-07-01 00:00:00
abstract：:Iris cyst excision involves complex surgical maneuvers and may have a variable visual outcome depending upon preexisting and postoperative complications. Hereby, we report a case series of 10 eyes from which posttraumatic iris cysts were excised and proven histopathologically. Histopathology records were reviewed. Dat...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.43383
更新日期：2008-11-01 00:00:00
abstract：:Simultaneous corneal cross-linking (CXL) has been proposed as an adjunct therapy to corneal refractive procedures to prevent future ectasia, especially when performed in borderline corneas. This review analyses the currently available literature (minimum follow-up 6 months) on corneal refractive surgery and simultaneo...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.4103/ijo.IJO_1709_20
更新日期：2020-12-01 00:00:00
abstract：BACKGROUND:Recent reports indicated that the slope of the foveal depression influences the macular pigment (MP) spatial profile. MP has been shown to confer possible protection against age-related macular degeneration (ARMD) because of its antioxidant properties. AIMS:To study the configuration of foveal slope and the f...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.119437
更新日期：2013-09-01 00:00:00
abstract：:Anterior segment infiltration in acute myeloid leukemia (AML) presenting as hypopyon uveitis is very rare. We report this case as an uncommon presentation in a patient on remission after bone marrow transplant for AML. In addition to the hypopyon, the patient presented with "red eye" caused by ocular surface disease d...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.83621
更新日期：2011-09-01 00:00:00
abstract：:Wet age-related macular degeneration and diabetic retinopathy are pathological consequences of vascular endothelial growth factor (VEGF) release as a reaction to deficiency of oxygen and nutrients in the macular cells. Conventional treatment modalities have been constrained by limited success. Convincing evidence exis...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.4103/0301-4738.36478
更新日期：2007-11-01 00:00:00
abstract：PURPOSE:To correlate fixation stability and retinal sensitivity measured by liquid crystal display (LCD) microperimetry to visual acuity in eyes with macular pathology. DESIGN:Retrospective chart review METHODS:The cohort included 26 eyes of 26 patients, divided into two groups according to visual acuity (Group 1 eye...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：2004-12-01 00:00:00
abstract：:Neurofibromatosis (NF) with sphenoid wing dysplasia is a rare clinical entity. Herewith, we present a case of NF with sphenoid wing dysplasia which presented with pulsatile progressive proptosis. Other ocular symptoms or visual disturbances were absent. Diagnosis of the condition was not easy and the management was a ...
journal_title：Indian journal of ophthalmology
pub_type：
doi：10.4103/ijo.IJO_429_17
更新日期：2018-01-01 00:00:00
abstract：PURPOSE:This study aims to investigate the levels of aqueous vascular endothelial growth factor (VEGF) in diabetic patient groups in comparison to normal subjects, and to correlate elevated VEGF with the severity of diabetic retinopathy (DR). MATERIALS AND METHODS:Aqueous samples were obtained from 78 eyes of 74 patie...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.67042
更新日期：2010-09-01 00:00:00
abstract：AIM:We sought to identify differences in the following measures of the ocular response analyser (ORA) between primary open angle glaucoma (POAG) and exfoliative glaucoma (EXG) patients: Corneal hysteresis (CH), corneal resistance factor (CRF), corneal-compensated intraocular pressure (IOPcc) and Goldmann-correlated int...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/0301-4738.138180
更新日期：2014-07-01 00:00:00
abstract：:Transepithelial photorefractive keratectomy (tPRK) promotes faster re-epithelialization which in turn can reduce the risk of infectious keratitis in the postoperative period. We present a case of a 22-year-old man with infectious keratitis in his left eye 8 days after an uneventful bilateral tPRK. A 2 mm × 5 mm anteri...
journal_title：Indian journal of ophthalmology
pub_type：
doi：10.4103/ijo.IJO_1730_20
更新日期：2020-12-01 00:00:00
abstract：:A young lady presented with very high vault and fixed dilated pupil along with optic capture of the implantable collamer lens (ICL). After thorough evaluation and ruling out the ICL sizing error, the optic capture was relieved and the ICL was rotated into vertical position. Single-pass four throw pupilloplasty was per...
journal_title：Indian journal of ophthalmology
pub_type：
doi：10.4103/ijo.IJO_3030_20
更新日期：2020-12-01 00:00:00
abstract：:In this case report, we demonstrate the use of optical coherence tomography angiography (OCTA) as a tool to evaluate intrinsic vasculature in a case of juxtapapillary melanoma which underwent ruthinium.106 plaque brachytherapy. In this case, OCTA could demonstrate a decrease in caliber and density of the intrinsic vas...
journal_title：Indian journal of ophthalmology
pub_type： 杂志文章
doi：10.4103/ijo.IJO_1928_18
更新日期：2019-12-01 00:00:00
