Human embryonic stem cell-derived mesenchymal cells preserve kidney function and extend lifespan in NZB/W F1 mouse model of lupus nephritis.

abstract：:Traumatic brain injury (TBI) causes brain edema that induces increased intracranial pressure and decreased cerebral perfusion. Decompressive craniectomy has been recommended as a surgical procedure for the management of swollen brain and intracranial hypertension. Proper location and size of a decompressive craniectom...

journal_title：Scientific reports

authors： Lambride C,Christodoulou N,Michail A,Vavourakis V,Stylianopoulos T

更新日期：2020-10-29 00:00:00

abstract：:The ideal strategy for hair cell regeneration is promoting residual supporting cell proliferation followed by induction of hair cell differentiation. In this study, cultured neonatal mouse organs of Corti were treated with neomycin to eliminate hair cells followed by incubation with recombined adenovirus expressing Pa...

journal_title：Scientific reports

authors： Chen Y,Yu H,Zhang Y,Li W,Lu N,Ni W,He Y,Li J,Sun S,Wang Z,Li H

更新日期：2013-10-21 00:00:00

abstract：:Pyriform sinus fistula (PSF) is a rare congenital entity. We hypothesized that clinical features, diagnosis and treatment may differ between newborns and children. 190 patients diagnosed with PSF were divided into two groups: neonatal (n = 15) and childhood (n = 175). The medical records including demographic and clin...

journal_title：Scientific reports

authors： Sheng Q,Lv Z,Xu W,Liu J

更新日期：2019-12-06 00:00:00

abstract：:We present and demonstrate an approach for femtosecond laser processing by using patterned vector optical fields (PVOFs) composed of multiple individual vector optical fields. The PVOFs can be flexibly engineered due to the diversity of individual vector optical fields in spatial arrangement and distribution of states...

journal_title：Scientific reports

authors： Lou K,Qian SX,Ren ZC,Tu C,Li Y,Wang HT

更新日期：2013-01-01 00:00:00

abstract：:FMS-like tyrosine kinase 3 (FLT3) is a key driver of acute myeloid leukemia (AML). Several tyrosine kinase inhibitors (TKIs) targeting FLT3 have been evaluated clinically, but their effects are limited when used in monotherapy due to the emergence of drug-resistance. Thus, a better understanding of drug-resistance pat...

journal_title：Scientific reports

authors： Morales ML,Arenas A,Ortiz-Ruiz A,Leivas A,Rapado I,Rodríguez-García A,Castro N,Zagorac I,Quintela-Fandino M,Gómez-López G,Gallardo M,Ayala R,Linares M,Martínez-López J

更新日期：2019-12-09 00:00:00

abstract：:Developing immunoassay for absolute quantitation of protein biomarkers in Formalin Fixed Paraffin Embedded (FFPE) samples promises improved objectivity, consistency and accuracy in daily clinical practice. The feasibility of Quantitative Dot Blot (QDB) method for this purpose was explored in this study. We were able t...

journal_title：Scientific reports

authors： Yu G,Zhang W,Zhang Y,Lv J,Wu S,Sui X,Zhang J,Tang F

更新日期：2020-07-27 00:00:00

abstract：:Previously, Aznar et al., showed that Daple/CCDC88C enables Wnt receptors to transactivate trimeric G-proteins during non-canonical Wnt signaling via a novel G-protein binding and activating (GBA) motif. By doing so, Daple serves two opposing roles; earlier during oncogenesis it suppresses neoplastic transformation an...

journal_title：Scientific reports

authors： Ear J,Dunkel Y,Mittal Y,Lim BBC,Liu L,Holda MK,Nitsche U,Barbazán J,Goel A,Janssen KP,Aznar N,Ghosh P

更新日期：2019-08-20 00:00:00

abstract：:We demonstrate synthesis of Ni/CuOx/Ni nanowires (NWs) by electrochemical deposition on anodized aluminum oxide (AAO) membranes. AAO with pore diameter of ~70 nm and pore length of ~50 μm was used as the template for synthesis of NWs. After deposition of Au as the seed layer, NWs with a structure of Ni/CuOx/Ni were gr...

journal_title：Scientific reports

authors： Park K,Lee JS

更新日期：2016-03-15 00:00:00

abstract：:Learning rules by which cell shape impacts cell function would enable control of cell physiology and fate in medical applications, particularly, on the interface of cells and material of the implants. We defined the phenotypic response of human bone marrow-derived mesenchymal stem cells (hMSCs) to 2176 randomly genera...

journal_title：Scientific reports

authors： Vasilevich AS,Vermeulen S,Kamphuis M,Roumans N,Eroumé S,Hebels DGAJ,van de Peppel J,Reihs R,Beijer NRM,Carlier A,Carpenter AE,Singh S,de Boer J

更新日期：2020-11-04 00:00:00

abstract：:The temporal dynamics of brain activation during visual and auditory perception of congruent vs. incongruent musical video clips was investigated in 12 musicians from the Milan Conservatory of music and 12 controls. 368 videos of a clarinetist and a violinist playing the same score with their instruments were presente...

journal_title：Scientific reports

authors： Proverbio AM,Calbi M,Manfredi M,Zani A

更新日期：2014-07-29 00:00:00

abstract：:Impurities in superconductors and their induced bound states are important both for engineering novel states such as Majorana zero-energy modes and for probing bulk properties of the superconducting state. The high-temperature cuprates offer a clear advantage in a much larger superconducting order parameter, but the n...

journal_title：Scientific reports

authors： Mashkoori M,Björnson K,Black-Schaffer AM

更新日期：2017-03-10 00:00:00

abstract：:Due to the substantial limitation of study population, Spindle cell sarcoma (SCS) was unexplored comprehensively. In this study, we investigated the clinical characteristics and disease specific prognostic factors of SCS. 3299 SCS cases were identified and extracted from Surveillance, Epidemiology, and End Results (SE...

journal_title：Scientific reports

authors： Feng L,Wang M,Yibulayin F,Zhang H,Yang YL,Ren F,Wushou A

更新日期：2018-03-22 00:00:00

abstract：:The sedimentary record, and associated micropalaeontological proxies, is one tool that has been employed to quantify a region's tropical cyclone history. Doing so has largely relied on the identification of allochthonous deposits (sediments and microfossils), sourced from deeper water and entrained by tropical cyclone...

journal_title：Scientific reports

authors： Strotz LC,Mamo BL,Dominey-Howes D

更新日期：2016-04-29 00:00:00

abstract：:Highly Tm(3+) doped optical fibers are urgently desirable for 2.0 μm compact single-frequency fiber laser and high-repetition-rate mode-locked fiber laser. Here, we systematically investigated the optical parameters, energy transfer processes and thermal properties of Tm(3+) doped barium gallo-germanate (BGG) glasses....

journal_title：Scientific reports

authors： Wen X,Tang G,Yang Q,Chen X,Qian Q,Zhang Q,Yang Z

更新日期：2016-02-01 00:00:00

abstract：:The nutritional alarmones ppGpp and pppGpp (collectively: (p)ppGpp) are nucleotide-based second messengers enabling bacteria to respond to environmental and stress conditions. Several bacterial species contain two highly homologous (p)ppGpp synthetases named RelP (SAS2, YwaC) and RelQ (SAS1, YjbM). It is established t...

journal_title：Scientific reports

authors： Steinchen W,Vogt MS,Altegoer F,Giammarinaro PI,Horvatek P,Wolz C,Bange G

更新日期：2018-02-01 00:00:00

abstract：:Despite the relevance of complex root microbial communities for plant health, growth and productivity, the molecular basis of these plant-microbe interactions is not well understood. Verrucomicrobia are cosmopolitans in the rhizosphere, nevertheless their adaptations and functions are enigmatic since the proportion of...

journal_title：Scientific reports

authors： Bünger W,Jiang X,Müller J,Hurek T,Reinhold-Hurek B

更新日期：2020-05-26 00:00:00

abstract：:Immunoglobulin A is the dominant antibody isotype found in mucosal secretions and enforces host-microbiota symbiosis in mice, yet selective IgA-deficiency (sIgAd) in humans is often described as asymptomatic. Here, we determined the effects of IgA deficiency on human gut microbiota composition and evaluated the possib...

journal_title：Scientific reports

authors： Catanzaro JR,Strauss JD,Bielecka A,Porto AF,Lobo FM,Urban A,Schofield WB,Palm NW

更新日期：2019-09-19 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Zhou Y,Sun W,Chen J,Tan H,Xiao Y,Li Q,Ji Q,Gao S,Chen L,Chen S,Zhang L,Chen W

更新日期：2020-04-24 00:00:00

abstract：:There is strong in vitro cell survival evidence that the relative biological effectiveness (RBE) of protons is variable, with dependence on factors such as linear energy transfer (LET) and dose. This is coupled with the growing in vivo evidence, from post-treatment image change analysis, of a variable RBE. Despite thi...

journal_title：Scientific reports

authors： Smith EAK,Henthorn NT,Warmenhoven JW,Ingram SP,Aitkenhead AH,Richardson JC,Sitch P,Chadwick AL,Underwood TSA,Merchant MJ,Burnet NG,Kirkby NF,Kirkby KJ,Mackay RI

更新日期：2019-12-27 00:00:00

abstract：:Although the growth of graphene by chemical vapor deposition is a production technique that guarantees high crystallinity and superior electronic properties on large areas, it is still a challenge for manufacturers to efficiently scale up the production to the industrial scale. In this context, issues related to the p...

journal_title：Scientific reports

authors： Lisi N,Dikonimos T,Buonocore F,Pittori M,Mazzaro R,Rizzoli R,Marras S,Capasso A

更新日期：2017-08-30 00:00:00

abstract：:For infants with acute progressive hydrocephalus, invasive drainage of cerebrospinal fluid (CSF) is performed until a ventriculo-peritoneal shunt can be inserted. Surrogate markers of intracranial pressure (ICP) may help optimise the timing of invasive procedures. To assess whether RI with/without fontanel compression...

journal_title：Scientific reports

authors： Yoshizuka T,Kinoshita M,Iwata S,Tsuda K,Kato T,Saikusa M,Shindou R,Hara N,Harada E,Takashima S,Takeshige N,Saitoh S,Yamashita Y,Iwata O

更新日期：2018-08-07 00:00:00

abstract：:Overexposure to intense noise can destroy the synapses between auditory nerve fibers and their hair cell targets without destroying the hair cells themselves. In adult mice, this synaptopathy is immediate and largely irreversible, whereas, in guinea pigs, counts of immunostained synaptic puncta can recover with increa...

journal_title：Scientific reports

authors： Hickman TT,Hashimoto K,Liberman LD,Liberman MC

更新日期：2020-11-17 00:00:00

abstract：:The Great Amazon Reef (GARS) is an extensive mesophotic reef ecosystem between Brazil and the Caribbean. Despite being considered as one of the most important mesophotic reef ecosystems of the South Atlantic, recent criticism on the existence of a living reef in the Amazon River mouth was raised by some scientists and...

journal_title：Scientific reports

authors： de Mahiques MM,Siegle E,Francini-Filho RB,Thompson FL,de Rezende CE,Gomes JD,Asp NE

更新日期：2019-09-23 00:00:00

abstract：:Vaccine trials and cohort studies in Plasmodium falciparum endemic areas indicate that naturally-acquired and vaccine-induced antibodies to merozoite surface protein 2 (MSP2) are associated with resistance to malaria. These data indicate that PfMSP2 has significant potential as a component of a multi-antigen malaria v...

journal_title：Scientific reports

authors： Eacret JS,Gonzales DM,Franks RG,Burns JM Jr

更新日期：2019-06-21 00:00:00

abstract：:Memory performance results from plasticity, the ability to change with experience. We show that benefit from practice over a few trials, learning slope, is predictive of long-term recall and hippocampal volume across a broad age range and a long period of time, relates to memory training benefit, and is heritable. Fir...

journal_title：Scientific reports

authors： Walhovd KB,Bråthen ACS,Panizzon MS,Mowinckel AM,Sørensen Ø,de Lange AG,Krogsrud SK,Håberg A,Franz CE,Kremen WS,Fjell AM

更新日期：2020-12-03 00:00:00

abstract：:The purpose of this study was to compare the performance of arrival-time-insensitive (ATI) and arrival-time-sensitive (ATS) computed tomography perfusion (CTP) algorithms in Philips IntelliSpace Portal (v9, ISP) and to investigate optimal thresholds for ATI regarding the prediction of final infarct volume (FIV). Retro...

journal_title：Scientific reports

authors： Pennig L,Thiele F,Goertz L,Laukamp KR,Perkuhn M,Kabbasch C,Schlamann M,Fink GR,Borggrefe J

更新日期：2020-06-09 00:00:00

abstract：:In external radiotherapy (RT), the use of flattening filter-free (FFF) radiation beams obtained by removing the flattening filter (FF) in standard linear accelerators is rapidly increasing, and the benefits of clinical use are the issue of research. Advanced treatment techniques have increased the interest in the oper...

journal_title：Scientific reports

authors： Arslan A,Sengul B

更新日期：2020-06-02 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the most common liver cancer, with a very poor prognosis. There is an urgent need for an effective therapy for HCC. Ginsenoside Rh2 (GRh2) has been shown to significantly inhibit growth of some types of cancer, whereas its effects on HCC have not been examined. Here, we treated human ...

journal_title：Scientific reports

authors： Yang Z,Zhao T,Liu H,Zhang L

更新日期：2016-01-19 00:00:00

abstract：:In this work, disordered-IrMn3/insulating-Y3Fe5O12 exchange-biased bilayers are studied. The behavior of the net magnetic moment ΔmAFM in the antiferromagnet is directly probed by anomalous and planar Hall effects, and anisotropic magnetoresistance. The ΔmAFM is proved to come from the interfacial uncompensated magnet...

journal_title：Scientific reports

authors： Zhou X,Ma L,Shi Z,Fan WJ,Evans RF,Zheng JG,Chantrell RW,Mangin S,Zhang HW,Zhou SM

更新日期：2015-03-17 00:00:00

abstract：:Manganese has long been employed as a T1-shortening agent in magnetic resonance imaging (MRI) applications, but these techniques are limited by the biotoxicity of bulk-manganese. Positron emission tomography (PET) offers superior contrast sensitivity compared with MRI, and recent preclinical PET studies employing 52gM...

journal_title：Scientific reports

authors： Graves SA,Hernandez R,Valdovinos HF,Ellison PA,Engle JW,Barnhart TE,Cai W,Nickles RJ

更新日期：2017-06-08 00:00:00