Abstract:
AIM:We have evaluated here the clinical and analytical performance of the Alere™ Heart Check (AHC) test, a rapid point-of-care immunoassay designed for the measurement of BNP from fresh capillary whole blood. PATIENTS & METHODS:One-hundred-and-sixty-three patients with stable chronic heart failure followed at the cardiac rehabilitation were submitted to simultaneous capillary (AHC) and plasma (Abbott architect system) BNP measurements. RESULTS:Both methods showed a good correlation, although the values diverged when BNP was higher than 2000 pg/ml. Despite a relatively poor precision of AHC, however, both methods showed the same performances to assess patients' dyspnea and equivalent sensitivity, specificity, negative and positive predicting values. CONCLUSION:AHC BNP test is a good POC for the management of heart failure despite a relatively poor precision.
journal_name
Biomark Medjournal_title
Biomarkers in medicineauthors
Monfort A,Da Silva K,Vodovar N,Gayat E,Cohen-Solal A,Manivet Pdoi
10.2217/bmm.15.95subject
Has Abstractpub_date
2015-01-01 00:00:00pages
1323-30issue
12eissn
1752-0363issn
1752-0371journal_volume
9pub_type
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