Urinary biomarkers of bladder cancer: an update and future perspectives.

abstract：:Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy and is the fifth leading cause of cancer deaths in women. Developing adjuvant therapy to circumvent drug resistance represents an important aspect of current initiatives to improve survival in women with advanced EOC. A regulatory molecule that ...

journal_title：Biomarkers in medicine

authors： Nagaraj AB,Joseph P,DiFeo A

更新日期：2015-01-01 00:00:00

abstract：:Letter in regards to: Akboga MK, Balci KG, Maden O et al. Usefulness of monocyte to HDL-cholesterol ratio to predict high SYNTAX score in patients with stable coronary artery disease. Biomark. Med. 10(4), 375-383 (2016). ...

journal_title：Biomarkers in medicine

authors： Soylemez S

更新日期：2017-08-01 00:00:00

abstract：AIM:Childhood cancer remains one of the main cause of death in the pediatric population. Amino acids (AAs) level alterations in plasma are considered to play a role in carcinogenesis and further course of the disease. METHODS:Seventy-seven children with cancer, including 47 with hematological and 30 with solid tumors ...

journal_title：Biomarkers in medicine

authors： Synakiewicz A,Sawicka-Zukowska M,Adrianowska N,Galezowska G,Ratajczyk J,Owczarzak A,Konieczna L,Stachowicz-Stencel T

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Circulating tumor cells (CTCs) and tumor-specific alterations in cell-free plasma DNA can both be used as markers of prognosis in breast cancer. To date, there have been no studies that have compared these as markers for subclinical metastases in the follow-up of early breast cancer. In this study, we measur...

journal_title：Biomarkers in medicine

authors： Shaw JA,Brown J,Coombes RC,Jacob J,Payne R,Lee B,Page K,Hava N,Stebbing J

更新日期：2011-02-01 00:00:00

abstract：:Heart failure remains an important clinical and public health problem with significant mortality, morbidity and economic consequences. The identification of natriuretic peptides and the large number of investigations that followed have led to a better understanding of the neurohormonal pathophysiology of heart failure...

journal_title：Biomarkers in medicine

authors： Miller WL,Targonski PV,Jaffe AS

更新日期：2007-12-01 00:00:00

abstract：:Background: Troponin levels may be elevated in COVID-19 infection. The aim of this study was to the explore relation between troponin levels and COVID-19 severity. Materials & methods/Results: One hundred and forty consecutive patients with COVID-19 pneumonia were included. Diagnosis of COVID-19 pneumonia was based on...

journal_title：Biomarkers in medicine

authors： Ileri C,Dogan Z,Ozben B,Karaoglu C,Gunay N,Tigen K,Basat S,Uyan C

更新日期：2021-01-27 00:00:00

abstract：:The current review article aims to provide an up-to-date summary of previous studies in humans that have reported the association between circulating endostatin levels and different cardiovascular phenotypes. We also aim to provide suggestions for future directions of future research evaluating endostatin as a clinica...

journal_title：Biomarkers in medicine

authors： Ruge T,Carlsson AC,Larsson A,Ärnlöv J

更新日期：2017-10-01 00:00:00

abstract：:Aim: To determine whether TLR9 polymorphisms are associated with tumor recurrence after liver transplantation for hepatocellular carcinoma (HCC). Patients & methods: All patients who underwent liver transplantation, and had viable HCC in the explanted liver were included. TLR9-1237C/T and -1486C/T polymorphisms were a...

journal_title：Biomarkers in medicine

authors： de la Fuente S,Citores MJ,Lucena JL,Muñoz P,Cuervas-Mons V

更新日期：2019-08-01 00:00:00

abstract：AIM:The conflicting relationships of serum omentin with inflammation markers and cardiometabolic disorders were investigated. Results & methods: Unselected 864 population-based middle-aged adults were cross-sectionally studied by sex-specific omentin tertiles. Men in the lowest omentin tertile (T1) had lower systolic b...

journal_title：Biomarkers in medicine

authors： Onat A,Ademoglu E,Karadeniz Y,Can G,Uzun AO,Simsek B,Kaya A

更新日期：2018-02-01 00:00:00

abstract：:Systemic sclerosis is an autoimmune inflammatory disorder of unknown etiologycharacterized b y pronounced fibroproliferative alterations in the microvasculature, and frequent cellular and humoral immunity abnormalities, culminating in a severe and often progressive fibrotic process. Numerous biomarkers reflecting the ...

journal_title：Biomarkers in medicine

authors： Castro SV,Jimenez SA

更新日期：2010-02-01 00:00:00

abstract：:Epilepsy and seizures are very common in the early years of life and are often associated with significant morbidity and mortality. Identification of biomarkers for the early detection of epileptogenicity, epileptogenesis, comorbidities, disease progression and treatment implementation will be very important in implem...

journal_title：Biomarkers in medicine

authors： Galanopoulou AS,Moshé SL

更新日期：2011-10-01 00:00:00

abstract：:In general, a biomarker has multiple uses such as a diagnostic tool and a method to monitor therapy. The quality of a biomarker depends on how big the difference is between, for example, patients and healthy controls, but also on the capacity of the method used to measure it (the uncertainty in the method should be mu...

journal_title：Biomarkers in medicine

authors： Andreasson U,Vanmechelen E,Shaw LM,Zetterberg H,Vanderstichele H

更新日期：2012-08-01 00:00:00

abstract：:Modern war wounds are complex and primarily involve extremities. They require multiple operative interventions to achieve wound closure and begin rehabilitation. Current assessment of the suitability of surgical wound closure is based upon subjective methods coupled with a semiquantitative determination of the wound b...

journal_title：Biomarkers in medicine

authors： Brown TS,Safford S,Caramanica J,Elster EA

更新日期：2010-06-01 00:00:00

abstract：AIM:Predicting a poor treatment outcome would offer significant benefits for patient care and for new drug development. Materials, methods & results: Urine samples from tuberculosis-positive patients with a successful and unsuccessful treatment outcome were collected at baseline and analyzed. The identified metabolites...

journal_title：Biomarkers in medicine

authors： Luies L,Reenen MV,Ronacher K,Walzl G,Loots DT

更新日期：2017-12-01 00:00:00

abstract：:Patients with metastatic colorectal cancer have a very poor prognosis. Incorporation of targeted molecular therapies, such as the anti-EGFR receptor monoclonal antibodies cetuximab and panitumumab, into treatment regimens has improved outcomes for patients with wild-type RAS tumors. Yet, response rates remain low and ...

journal_title：Biomarkers in medicine

authors： Caiazza F,Elliott L,Fennelly D,Sheahan K,Doherty GA,Ryan EJ

更新日期：2015-01-01 00:00:00

abstract：:Acute kidney injury is a common and significant complication among pediatric patients with congenital heart disease, occurring most commonly after cardiopulmonary bypass. Current laboratory methods of diagnosis are not timely enough to guide management decisions, thus spurring interest in discovering new biomarkers of...

journal_title：Biomarkers in medicine

authors： Kwiatkowski DM,Goldstein SL,Krawczeski CD

更新日期：2012-06-01 00:00:00

abstract：:Aim: We aimed to explore the biomarkers for disease progression or the risk of nonsurvivors. Materials & methods: This study included 134 hospitalized patients with confirmed COVID-19 infection. The outcome of moderate versus severe versus critically ill patients and survivors versus nonsurvivors were compared. Result...

journal_title：Biomarkers in medicine

authors： Li J,Li M,Zheng S,Li M,Zhang M,Sun M,Li X,Deng A,Cai Y,Zhang H

更新日期：2020-07-01 00:00:00

abstract：:With increasing knowledge of the regulatory mechanisms of G-protein-coupled receptor signaling in heart physiology, many studies have focused on the role of this system in cardiovascular disease. In recent years, scientists have moved their attention from the receptors to their regulatory proteins: the G-protein-coupl...

journal_title：Biomarkers in medicine

authors： Campanile A,Iaccarino G

更新日期：2009-10-01 00:00:00

abstract：:Aim: Noninvasive assessments of C-reactive protein (CRP) in stress contexts have seldom been compared. This study evaluated CRP response to acute social stress as measured in saliva and dried blood spot (DBS). Materials & methods: African-Americans (N = 118; mean age = 32 years) participated in a laboratory-based soci...

journal_title：Biomarkers in medicine

authors： Goetz SM,Lucas T

更新日期：2020-04-01 00:00:00

abstract：:Background: The Tp-e/QT (peak to end of T-wave duration/QT interval) ratio is a promising marker of myocardial repolarization and ventricular arrhythmogenesis. Its elevation is associated with sudden cardiac death in different clinical conditions. This study was designed to assess the possible association between incr...

journal_title：Biomarkers in medicine

authors： Fang J,Su H,Song A,Tong Y,Huang Z,Ding F,Liu Y

更新日期：2020-12-01 00:00:00

abstract：:Interferons (IFNs) comprise type I, II and III families with multiple subtypes. Via transcription of IFN-stimulated genes (ISGs), IFNs can exert multiple biological effects on the cell. In infectious and chronic inflammatory diseases, the IFNs and their ISG sets can be potentially utilized as biomarkers of disease out...

journal_title：Biomarkers in medicine

authors： Berry CM,Hertzog PJ,Mangan NE

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Autism spectrum disorder (ASD) represents a wide range of neurodevelopmental disorders characterized by impairments in social interaction, language, communication and range of interests. Autism is usually diagnosed in children 3-5 years of age using behavioral characteristics; thus, diagnosis shortly after b...

journal_title：Biomarkers in medicine

authors： Mizejewski GJ,Lindau-Shepard B,Pass KA

更新日期：2013-04-01 00:00:00

abstract：:Biomarker discovery is essential to the advancement of our knowledge about diseases and to the development of new strategies for treatment and therapy. Among the newest technologies in this rapidly growing field is a process termed Cell SELEX by which a panel of aptamers can be generated to specifically target disease...

journal_title：Biomarkers in medicine

authors： Kim Y,Liu C,Tan W

更新日期：2009-04-01 00:00:00

abstract：:The prevalence of metabolic disorders (MDs), especially diabetes, is rapidly increasing worldwide, leading to an increasing risk of cardiovascular and other socially relevant complications. To boost MD biomarker discovery, advanced proteomics can harmonize metabolomics. Indeed, the rapid development of mass spectromet...

journal_title：Biomarkers in medicine

authors： Di Girolamo F,Del Chierico F,Caenaro G,Lante I,Muraca M,Putignani L

更新日期：2012-12-01 00:00:00

abstract：AIM:Ankylosing spondylitis (AS) is a chronic systemic inflammatory rheumatic disorder that primarily affects the axial skeleton. To date there is no satisfactory biomarker for diagnosis or prognosis of AS. This study is focused on detection of potential biomarkers for the diagnosis of AS using surface-enhanced laser de...

journal_title：Biomarkers in medicine

authors： Bons JA,van der Heijde D,Bouwman FG,Mariman EC,van Dieijen-Visser MP,Landewé R,van der Linden S,Wodzig WK

更新日期：2008-02-01 00:00:00

abstract：AIM:Several lines of evidence exist which suggest that changes in the expression of circulating cytokines are linked to the development or reoccurrence of multiple sclerosis (MS). This study aimed to evaluate the serum levels of relevant cytokines after therapy with IFN-β formulations in MS patients. MATERIALS & METHO...

journal_title：Biomarkers in medicine

authors： Arababadi MK,Mosavi R,Khorramdelazad H,Yaghini N,Zarandi ER,Araste M,Pourali R,Nekhei Z,Kennedy D

更新日期：2010-10-01 00:00:00

abstract：AIM:The aim of the present study was to investigate the association of circulating miRNAs with white-coat hypertension (WCH) and further analyze whether miRNAs could be as potential biomarkers for WCH. METHOD:Quantitative reverse transcriptase PCR (qRT-PCR) was used to evaluate the expression of selected miRNAs. The a...

journal_title：Biomarkers in medicine

authors： Huang YQ,Huang C,Chen JY,Li J,Feng YQ

更新日期：2016-12-01 00:00:00

abstract：:Relationships between plasma drug concentrations and clinical outcome have been defined for various chemotherapeutic agents, showing that drug exposure may be a marker of toxicity, mainly hematological and gastrointestinal toxicity, as well as efficacy, expressed as tumor response and survival. Biomarkers provide info...

journal_title：Biomarkers in medicine

authors： Meza-Junco J,Sawyer MB

更新日期：2009-12-01 00:00:00

abstract：:Currently, decision-making for breast cancer treatment in the clinical setting is mainly based on clinical data, histomorphological features of the tumor tissue and a few cancer biomarkers such as steroid hormone receptor status (estrogen and progesterone receptors) and oncoprotein HER2 status. Although various therap...

journal_title：Biomarkers in medicine

authors： Napieralski R,Brünner N,Mengele K,Schmitt M

更新日期：2010-08-01 00:00:00

abstract：:Malignant pleural mesothelioma (MPM) is a highly aggressive and invasive tumor, whose incidence is expected to peak, in many countries, at the end of the present decade, 20-40 years after the peak of asbestos use (asbestos being the most important etiological factor). MPM has a poor prognosis, in part, owing to a diff...

journal_title：Biomarkers in medicine

authors： Cristaudo A,Bonotti A,Simonini S,Bruno R,Foddis R

更新日期：2011-04-01 00:00:00