Biomarker use in tailored combat casualty care.

abstract：:Aim: To investigate the role of endothelial PV-1 in patients with untreated celiac disease (CD)-associated liver injury. Materials & methods: PV-1 and PV-1 mRNA were measured in intestinal biopsies from untreated CD patients with elevated or normal alanine transaminase levels, controls, patients with inflammatory bowe...

journal_title：Biomarkers in medicine

authors： De Leo L,Naviglio S,Vatta S,Benelli E,Stera G,Santon D,Ziberna F,Taddio A,Martelossi S,Giudici F,Giuffrida P,Di Sabatino A,Corazza GR,Ventura A,Not T

更新日期：2020-12-01 00:00:00

abstract：:The 44th Congress of the International Society of Oncology and Biomarkers: Rio de Janeiro, Brazil, 7-10 September 2017 The 44th congress followed the previous one of  International Society of Oncology and Biomarkers (ISOBM) that took place in Chicago (USA) in 2016. The title of the 44th Annual congress was: 'Biomarker...

journal_title：Biomarkers in medicine

authors： Kinkorová J

更新日期：2018-02-01 00:00:00

abstract：AIM:This study aimed to identify plasma protein changes in a rat model of ischemic stroke using a proteomic approach. MATERIALS & METHODS:Four male Sprague-Dawley rats (3-6 months old) were subjected to 90 min of left middle cerebral artery occlusion under anesthesia with 1.5% isoflurane in O(2)/air followed by 24-h r...

journal_title：Biomarkers in medicine

authors： Chen R,Vendrell I,Chen CP,Cash D,O'Toole KG,Williams SA,Jones C,Preston JE,Wheeler JX

更新日期：2011-12-01 00:00:00

abstract：:In this work, we review the main available computational methods of identifying biomarkers of complex diseases from high-throughput data. The emerging omics techniques provide powerful alternatives to measure thousands of molecules in cells in parallel manners. The generated genomic, transcriptomic, proteomic, metabol...

journal_title：Biomarkers in medicine

authors： Liu ZP

更新日期：2016-06-01 00:00:00

abstract：AIM:To investigate the clinical significance of detecting several biomarkers collectively in the diagnosis of rheumatoid arthritis (RA). METHODS:128 RA patients, 174 non-RA patients and 80 healthy controls were enrolled. HLA-DR4 and HLA-DR53 were detected by the PCR-SSP method, 14-3-3η protein, anti-CCP and anti-Sa we...

journal_title：Biomarkers in medicine

authors： Tan L,Wang Q,Zeng T,Long T,Guan X,Wu S,Zheng W,Fu H,Meng Y,Wu Y,Tian Y,Yu J,Chen J,Li H,Cao L

更新日期：2018-07-01 00:00:00

abstract：:Combination antiretroviral therapy (cART) has significantly reduced morbidity and mortality of HIV-infected patients, yet their life expectancy remains reduced compared with the general population. Most HIV-infected patients receiving cART have some persistent immune dysfunction characterized by chronic immune activat...

journal_title：Biomarkers in medicine

authors： Lichtfuss GF,Hoy J,Rajasuriar R,Kramski M,Crowe SM,Lewin SR

更新日期：2011-04-01 00:00:00

abstract：AIM:The association between Lipoprotein (a) (Lp [a]) and common carotid intima media thickness (IMT) has been evaluated in 222 menopausal women. MATERIAL & METHODS:Lp (a) and IMT were measured, carotid ultrasound examination (B-Mode imaging) was performed and mean max IMT was calculated. RESULTS:Lp (a) was significan...

journal_title：Biomarkers in medicine

authors： Gentile M,Iannuzzo G,Mattiello A,Marotta G,Iannuzzi A,Panico S,Rubba P

更新日期：2016-01-01 00:00:00

abstract：:Relationships between plasma drug concentrations and clinical outcome have been defined for various chemotherapeutic agents, showing that drug exposure may be a marker of toxicity, mainly hematological and gastrointestinal toxicity, as well as efficacy, expressed as tumor response and survival. Biomarkers provide info...

journal_title：Biomarkers in medicine

authors： Meza-Junco J,Sawyer MB

更新日期：2009-12-01 00:00:00

abstract：:In recent years, immune checkpoint inhibitors have rapidly changed treatment paradigms and have been pivotal for the treatment of advanced NSCLC patients. However, many patients don't respond to immunotherapy, and toxicities are a concern. Mounting evidence suggests that PD-L1 expression and tumor mutational burden ar...

journal_title：Biomarkers in medicine

authors： C Guven D,Sahin TK,Dizdar O,Kilickap S

更新日期：2020-10-01 00:00:00

abstract：AIM:Several lines of evidence exist which suggest that changes in the expression of circulating cytokines are linked to the development or reoccurrence of multiple sclerosis (MS). This study aimed to evaluate the serum levels of relevant cytokines after therapy with IFN-β formulations in MS patients. MATERIALS & METHO...

journal_title：Biomarkers in medicine

authors： Arababadi MK,Mosavi R,Khorramdelazad H,Yaghini N,Zarandi ER,Araste M,Pourali R,Nekhei Z,Kennedy D

更新日期：2010-10-01 00:00:00

abstract：:The application of genomic medicine to the treatment of nicotine dependence holds great promise for revitalizing the steady decline in smoking rates witnessed in the USA over the past several decades. This paper examines the current knowledge base concerning the use of biomarkers to guide the selection of nicotine dep...

journal_title：Biomarkers in medicine

authors： Schnoll RA,Leone FT

更新日期：2011-12-01 00:00:00

abstract：:The uPA system mainly comprises the urokinase-type plasminogen activator uPA, the cell-surface receptor uPA receptor and the inhibitor PAI-1. Its clinical and prognostic impact especially in breast cancer is well investigated. In this short report, we summarize the published data describing expression of uPA, PAI-1 an...

journal_title：Biomarkers in medicine

authors： Taubert H,Magdolen V,Kotzsch M

更新日期：2013-06-01 00:00:00

abstract：:The uncertainty of whether/how to treat asymptomatic patients with isolated severe aortic stenosis and normal left ventricular ejection fraction is one of the most topical in cardiovascular medicine. Recently, the AVATAR trial: first ever randomized trial in the setting of aortic stenosis has been started in an attemp...

journal_title：Biomarkers in medicine

authors： Banovic MD

更新日期：2017-04-01 00:00:00

abstract：:Cardiac troponin is the standard biomarker for the diagnosis of acute myocardial infarction (AMI) and risk stratification for short-term adverse cardiac events (death, AMI or need for revascularization). Unfortunately, the concentration of troponin in blood is normal in AMI patients who present early after the onset o...

journal_title：Biomarkers in medicine

authors： Wu AH

更新日期：2007-06-01 00:00:00

abstract：:The current review article aims to provide an up-to-date summary of previous studies in humans that have reported the association between circulating endostatin levels and different cardiovascular phenotypes. We also aim to provide suggestions for future directions of future research evaluating endostatin as a clinica...

journal_title：Biomarkers in medicine

authors： Ruge T,Carlsson AC,Larsson A,Ärnlöv J

更新日期：2017-10-01 00:00:00

abstract：:Aim: Noninvasive assessments of C-reactive protein (CRP) in stress contexts have seldom been compared. This study evaluated CRP response to acute social stress as measured in saliva and dried blood spot (DBS). Materials & methods: African-Americans (N = 118; mean age = 32 years) participated in a laboratory-based soci...

journal_title：Biomarkers in medicine

authors： Goetz SM,Lucas T

更新日期：2020-04-01 00:00:00

abstract：:Acute kidney injury is a common and significant complication among pediatric patients with congenital heart disease, occurring most commonly after cardiopulmonary bypass. Current laboratory methods of diagnosis are not timely enough to guide management decisions, thus spurring interest in discovering new biomarkers of...

journal_title：Biomarkers in medicine

authors： Kwiatkowski DM,Goldstein SL,Krawczeski CD

更新日期：2012-06-01 00:00:00

abstract：:Letter in regards to: Akboga MK, Balci KG, Maden O et al. Usefulness of monocyte to HDL-cholesterol ratio to predict high SYNTAX score in patients with stable coronary artery disease. Biomark. Med. 10(4), 375-383 (2016). ...

journal_title：Biomarkers in medicine

authors： Soylemez S

更新日期：2017-08-01 00:00:00

abstract：:Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy and is the fifth leading cause of cancer deaths in women. Developing adjuvant therapy to circumvent drug resistance represents an important aspect of current initiatives to improve survival in women with advanced EOC. A regulatory molecule that ...

journal_title：Biomarkers in medicine

authors： Nagaraj AB,Joseph P,DiFeo A

更新日期：2015-01-01 00:00:00

abstract：AIM:To evaluate the relationship between mean platelet volume (MPV) and red cell distribution width (RDW), and disease activity in rheumatoid arthritis (RA). PATIENTS & METHODS:Hundred RA and 100 controls were included. RESULTS:MPV and RDW were higher in RA (p < 0.0001). The cut-off levels of RDW and MPV were 14.8 an...

journal_title：Biomarkers in medicine

authors： Tecer D,Sezgin M,Kanık A,İncel NA,Çimen ÖB,Biçer A,Şahin G

更新日期：2016-09-01 00:00:00

abstract：AIM:This meta-analysis was designed to analyze and evaluate the prognostic role of preoperative or pretreatment platelet-to-lymphocyte ratio (PLR) in patients with colorectal cancer (CRC). METHOD:We searched PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, Chinese Biomedical L...

journal_title：Biomarkers in medicine

authors： Min GT,Wang YH,Yao N,Zhao JM,Wang J,Wang HP,Chen W,Deng SJ,Li YM

更新日期：2017-01-01 00:00:00

abstract：AIM:Investigate the correlation between paraoxonase 2 (PON2) Ser311Cys polymorphism as well as the peroxisome proliferator-activated receptor gamma (PPARG) His477His polymorphism and the susceptibility to development of coronary heart diseases (CHD) through a meta-analysis. METHODS:Odds ratio and the corresponding 95%...

journal_title：Biomarkers in medicine

authors： González-Castro TB,Tovilla-Zárate CA,Juárez-Rojop IE,Hernández-Díaz Y,López-Narváez ML,Rodríguez-Pérez C,González-Hernández YK,Ramos-Méndez MÁ

更新日期：2018-03-01 00:00:00

abstract：:Background: We aimed to assess the predictive value of the absolute and relative intact parathormone (iPTH) decline levels as reliable markers of postoperative hypocalcemia. Materials & methods: iPTH levels were measured 4 h after surgery and the following morning after surgery (postoperative day 1). iPTH, absolute iP...

journal_title：Biomarkers in medicine

authors： Rajan S,Ravindhran B,George B,Bantwal G,Vageesh Ayyar,Mohan LN

更新日期：2020-08-01 00:00:00

abstract：AIM:Predicting a poor treatment outcome would offer significant benefits for patient care and for new drug development. Materials, methods & results: Urine samples from tuberculosis-positive patients with a successful and unsuccessful treatment outcome were collected at baseline and analyzed. The identified metabolites...

journal_title：Biomarkers in medicine

authors： Luies L,Reenen MV,Ronacher K,Walzl G,Loots DT

更新日期：2017-12-01 00:00:00

abstract：:With the regulatory approvals in Europe and the USA of trastuzumab-based anti-HER2 targeted therapy for upper gastrointestinal cancers in 2010, HER2 testing has now become universal for newly diagnosed cases of both breast cancer and adenocarcinomas of esophagus, stomach and gastroesophageal origin. In the 12 years or...

journal_title：Biomarkers in medicine

authors： Ross JS

更新日期：2011-06-01 00:00:00

abstract：:Increasing evidence has highlighted the roles of oxidative stress and inflammation in the promotion of atherosclerotic cardiovascular disease. Recent pathological studies have elucidated specific mediators that appear to link these pathways to the progression and rupture of atherosclerotic plaque in the artery wall. T...

journal_title：Biomarkers in medicine

authors： Uno K,Nicholls SJ

更新日期：2010-06-01 00:00:00

abstract：:Background: This study aimed to identify glioblastoma prognosis-associated genes with potential diagnosis or prognosis values using integrated bioinformatics analysis. Results: In total, 1831 differentially expressed genes (DEGs) between the glioblastoma and control samples were identified and were clustered into seve...

journal_title：Biomarkers in medicine

authors： Wang D,Liu J,Chen Q,Yang R,Jiang Q

更新日期：2020-11-01 00:00:00

abstract：:This article focuses on biochemical markers that may be used in the diagnostics of Parkinson's disease and associated disorders, and to identify early cases and stratify patients into subgroups. We present an updated account of some currently available candidate fluid biomarkers, and discuss their diagnostic performan...

journal_title：Biomarkers in medicine

authors： Nyhlén J,Constantinescu R,Zetterberg H

更新日期：2010-10-01 00:00:00

abstract：:Aim: We aimed to explore the biomarkers for disease progression or the risk of nonsurvivors. Materials & methods: This study included 134 hospitalized patients with confirmed COVID-19 infection. The outcome of moderate versus severe versus critically ill patients and survivors versus nonsurvivors were compared. Result...

journal_title：Biomarkers in medicine

authors： Li J,Li M,Zheng S,Li M,Zhang M,Sun M,Li X,Deng A,Cai Y,Zhang H

更新日期：2020-07-01 00:00:00

abstract：:Preeclampsia remains a significant cause of maternal morbidity and mortality worldwide. Prediction, diagnosis and management continue to be challenging but advances in the understanding of the pathophysiological processes underlying the disease has enabled identification of multiple biomarkers, some of which aid predi...

journal_title：Biomarkers in medicine

authors： Griffin M,Shennan AH

更新日期：2014-01-01 00:00:00