Abstract:
AIM:The aim of this article was to investigate the performance and predictive value of urinary liver-type FABP (uL-FABP) and urinary NGAL (uNGAL) for renal function and prognosis in obstructive nephropathy (ON). PATIENTS & METHODS:A total of 108 ON patients and urine samples were collected. An ELISA was used to determine the uL-FABP and uNGAL levels. A total of 90 patients completed the 1-year follow-up and were used to evaluate the predictive value of uL-FABP and uNGAL for the renal prognosis in ON. RESULTS:During the 1-year renal function follow-up, the uL-FABP level was significantly correlated with poor prognosis. When the preoperative uL-FABP and uNGAL or 72-h postoperative uL-FABP and uNGAL levels were combined, the areas under the curve for renal prognosis were 0.968 and 0.952, respectively. CONCLUSION:uL-FABP was helpful for the prediction of renal prognosis in ON. The combination of uL-FABP and uNGAL increased the accuracy of prediction.
journal_name
Biomark Medjournal_title
Biomarkers in medicineauthors
Xie Y,Xu W,Wang Q,Shao X,Ni Z,Mou Sdoi
10.2217/bmm.13.136subject
Has Abstractpub_date
2014-01-01 00:00:00pages
543-56issue
4eissn
1752-0363issn
1752-0371journal_volume
8pub_type
杂志文章abstract::The current review article aims to provide an up-to-date summary of previous studies in humans that have reported the association between circulating endostatin levels and different cardiovascular phenotypes. We also aim to provide suggestions for future directions of future research evaluating endostatin as a clinica...
journal_title:Biomarkers in medicine
pub_type: 杂志文章,评审
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更新日期:2017-10-01 00:00:00
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journal_title:Biomarkers in medicine
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journal_title:Biomarkers in medicine
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journal_title:Biomarkers in medicine
pub_type: 杂志文章,评审
doi:10.2217/bmm.09.71
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abstract::Clinical proteomics has great promise, but many hurdles. Proteomic approaches may prove to be the answer to decades of frustrating searches for markers that are specific and selective for breast cancer. In order to achieve this goal, the challenge arises that breast cancer is a heterogeneous disease and individual var...
journal_title:Biomarkers in medicine
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journal_title:Biomarkers in medicine
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更新日期:2013-06-01 00:00:00
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journal_title:Biomarkers in medicine
pub_type: 杂志文章
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journal_title:Biomarkers in medicine
pub_type: 杂志文章
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journal_title:Biomarkers in medicine
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journal_title:Biomarkers in medicine
pub_type: 杂志文章
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abstract:AIM:LncRNAs may act as promising biomarkers in esophageal cancer (EC). Here, we illustrate the LncRNA profile and their clinical relevance in EC. PATIENTS & METHODS:In this study, we utilized the Cancer Genome Atlas RNA-sequencing and clinical data from 186 patients and 13 normal samples. Various statistical and gene ...
journal_title:Biomarkers in medicine
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abstract::Cardiovascular disease refers to different diseases involving the heart and/or the arteries and/or the veins. Cardiovascular disease, overall considered, is a notable source of morbidity and mortality worldwide. Therefore, several research studies are dedicated to explore, by means of biomarkers, the possiblity to cal...
journal_title:Biomarkers in medicine
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journal_title:Biomarkers in medicine
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journal_title:Biomarkers in medicine
pub_type: 杂志文章
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更新日期:2017-08-01 00:00:00
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journal_title:Biomarkers in medicine
pub_type: 杂志文章,评审
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更新日期:2012-12-01 00:00:00
abstract::Autophagy is a catabolic process associated with intracellular self-digestion of damaged organelles or redundant proteins enabling maintenance of cell homeostasis. It is accepted that impaired autophagy is closely linked to cancer development and has been extensively studied in a variety of malignancies including colo...
journal_title:Biomarkers in medicine
pub_type: 杂志文章,评审
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journal_title:Biomarkers in medicine
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journal_title:Biomarkers in medicine
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journal_title:Biomarkers in medicine
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更新日期:2010-02-01 00:00:00
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journal_title:Biomarkers in medicine
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journal_title:Biomarkers in medicine
pub_type: 杂志文章
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更新日期:2017-03-01 00:00:00
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journal_title:Biomarkers in medicine
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abstract::Combination antiretroviral therapy (cART) has significantly reduced morbidity and mortality of HIV-infected patients, yet their life expectancy remains reduced compared with the general population. Most HIV-infected patients receiving cART have some persistent immune dysfunction characterized by chronic immune activat...
journal_title:Biomarkers in medicine
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更新日期:2011-04-01 00:00:00
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journal_title:Biomarkers in medicine
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更新日期:2011-02-01 00:00:00
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journal_title:Biomarkers in medicine
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journal_title:Biomarkers in medicine
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journal_title:Biomarkers in medicine
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