Abstract：
PURPOSE:For the treatment of persistent post-prostatectomy incontinence (PPI), several surgical treatment options including male slings are available. In 2010, the second generation of the retrourethral male sling Advance, AdVanceXP, was introduced. Aim of the study was to examine in a prospective multicentre study the outcome of AdVanceXP in the treatment of PPI. METHODS:Ninety-four patients were treated with AdVanceXP. Patients with nocturnal incontinence, previous incontinence surgery, with coaptive zone <1 cm and irradiated patients were excluded. Measurements included: daily pad usage, 24-h pad weight test, post-operative pain in the visual analogue scale, International Quality of Life questionnaire, International Consultation on Incontinence Questionnaire short form, IEEF5 and Patient Global Impression of Improvement. Adverse events were recorded. All patients with no pads and 0-5 g in the 24-h pad test were defined as cured and those with a reduction in urine loss >50 % as improved. RESULTS:Preoperatively, the median 24-h pad weight test was 274 g and daily pad usage was 3. At 1-year follow-up, 66.3 % of patients could be classified as cured and 25.3 % as improved. After 2 years, 73.1 % could be classified as cured and 19.6 % as improved. Urine loss decreased (p < 0.001), and quality of life improved significantly (p < 0.001). Mean PGI was 1.5 after 1 year and 1.4 after 2 years. Majority of complications were minor. No intraoperative complications and five serious post-operative events occurred (grade IIIB complications). No explantation was necessary. CONCLUSIONS:AdVanceXP, when correctly indicated, shows good effectiveness and low complication rates after up to 2 years.
journal_name
World J Uroljournal_title
World journal of urologyauthors
Bauer RM,Gozzi C,Klehr B,Kretschmer A,Grabbert M,Rehder P,May F,Stief CG,Gebhartl P,Homberg Rdoi
10.1007/s00345-015-1731-0subject
Has Abstractpub_date
2016-07-01 00:00:00pages
1025-30issue
7eissn
0724-4983issn
1433-8726pii
10.1007/s00345-015-1731-0journal_volume
34pub_type
杂志文章,多中心研究abstract：:To understand alterations to the urokinase system that may occur in progressively metastatic prostate cancer cells, we assessed urokinase plasminogen activator receptor (uPAR) expression, in vitro motility towards vitronectin, urokinase plasminogen activator (uPA)-induced growth and growth factor regulation of uPAR ex...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-003-0395-3
更新日期：2004-04-01 00:00:00
abstract：:Growth and morphogenesis of the prostate involves mesenchymal-epithelial interactions. Transforming growth factor-beta 1 (TGF-beta1) is one growth factor that may play a role in these paracrine interactions. We have localized TGF-beta1 by molecular and immunohistochemical analysis in the developing mouse prostate. Acc...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/BF00191212
更新日期：1995-01-01 00:00:00
abstract：BACKGROUND:The anti-androgen withdrawal syndrome (AAWS) can be seen in one-third of patients after discontinuation of first-generation non-steroidal anti-androgen therapy. With the introduction of new agents for anti-androgen therapy as well as alternate mechanisms of action, new therapeutic options before and after do...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-014-1288-3
更新日期：2014-10-01 00:00:00
abstract：PURPOSE:Living donor nephrectomy is a high-stake procedure involving healthy individuals, therefore every effort should be made to define each patient's individualized risk and improve potential donors' information. The aim of this study was to evaluate the interest of the Mayo adhesive probability (MAP) score, an imag...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-020-03513-4
更新日期：2020-11-11 00:00:00
abstract：:Reconstruction of long anterior urethral strictures that cannot be excised and reanastomosed remains controversial. We critically reviewed the literature on free-graft and pedicled skin-flap urethroplasty to determine the optimal method of repair. Overall, free grafts were successful in 84.3% of cases and flaps, in 85...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s003450050048
更新日期：1998-01-01 00:00:00
abstract：OBJECTIVE:Radiation for tumors arising in the pelvis has been utilized for over a 100 years. Adverse effects (AEs) of radiotherapy (RT) continue to accumulate with time and are reported to show decades after treatment. The benefit of RT for pelvic tumors is well described as is their acute AEs. Late AEs are less well d...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-010-0603-x
更新日期：2011-02-01 00:00:00
abstract：PURPOSE:Erectile dysfunction (ED) is an early sign of vascular dysfunction. Studies have reported a correlation between arterial stiffness and cardiovascular events. The objective of this study was to evaluate the association among different criteria for assessing arterial stiffness and cardiovascular risk factors in E...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-009-0486-x
更新日期：2010-10-01 00:00:00
abstract：PURPOSE:Oxidative stress is believed to be one of the important etiologies in carcinogenesis that has not been systemically investigated in urothelial carcinoma (UC). Through data mining from a published transcriptomic database of UC of urinary bladders (UBUCs) (GSE31684), glutathione peroxidase 2 (GPX2) was identified...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-015-1522-7
更新日期：2015-11-01 00:00:00
abstract：PURPOSE:To investigate the impact of gender differences on treatment success, intraoperative and postoperative complications in patients undergoing ureteroscopy (URS). MATERIALS AND METHODS:A prospectively maintained database of 927 consecutively performed ureteroscopies on solitary ureteral stones in four different c...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-014-1435-x
更新日期：2015-09-01 00:00:00
abstract：:Animal models are at the centre of laboratory bladder cancer (BC) research and at the same time, the bridge to the clinic. A new and very promising therapeutical approach is to silence abnormally up-regulated genes in cancer, through small interfering RNA (siRNA) molecules. Therapeutic use and success of siRNAs will l...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-009-0374-4
更新日期：2009-06-01 00:00:00
abstract：PURPOSE:To evaluate the present human-based evidence that diet is related to the risk and outcome of prostate cancer. METHODS:Review of major case-control and cohort studies, and experimental trials evaluating the effect of diet or dietary constituents on the risk of prostate cancer. RESULTS:Although non-experimental...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-011-0810-0
更新日期：2012-04-01 00:00:00
abstract：PURPOSE:To report our experience with pelvic reconstructive surgery with transobturator mesh implants in elderly women. MATERIALS AND METHODS:A total of 32 women aged >75 years with pelvic organ prolapse receiving anterior and/or posterior repair using transobturator mesh implants were included. Concomitant mid-urethr...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-012-0863-8
更新日期：2013-06-01 00:00:00
abstract：OBJECTIVES:To characterize testosterone profile changes over time in a cohort of prostate cancer (PCa) patients managed with active surveillance (AS) and to assess its correlation with the initial disease characteristics and further progression. METHODS:We conducted retrospective chart review of PCa patients managed w...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2270-2
更新日期：2018-08-01 00:00:00
abstract：:The cost of urethral catheterisation injury (UCI) is significant, but the true incidence of patient care error is difficult to establish in the absence of specific hospital codes recording difficult urethral catheterisation (DUC) and UCI. For many years urologists are familiar passing a non-traumatic hydrophilic guide...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2499-9
更新日期：2019-04-01 00:00:00
abstract：PURPOSE:To investigate the effects of onabotulinum toxin type A (Onabot/A) intravesical injections on urinary and sexual function in a group of patients affected by multiple sclerosis (MS). METHODS:We enrolled 31 MS female patients with symptoms of overactive bladder and detrusor overactivity. All patients underwent u...
journal_title：World journal of urology
pub_type： 临床试验,杂志文章
doi：10.1007/s00345-015-1578-4
更新日期：2015-12-01 00:00:00
abstract：PURPOSE:To review the United States National Cancer Database (NCDB) from 2004 to 2015 and analyze survival outcomes of invasive non-urachal adenocarcinoma based on treatment modality. METHODS:The NCDB 2004-2015 bladder dataset was queried for adenocarcinoma histology, excluding urachal variant, and limited to patients...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2411-7
更新日期：2019-03-01 00:00:00
abstract：PURPOSE:To characterize the clinical and pathologic staging of patients with urothelial carcinoma (UC) in bladder diverticula (BD) after undergoing radical cystectomy (RC) and determine the impact of UCBD on recurrence and survival. METHODS:We reviewed our institutional database of patients who underwent RC for UC (19...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-014-1472-5
更新日期：2015-10-01 00:00:00
abstract：:Peyronie's disease (PD, induratio penis plastica) is uncommon. Its etiology is unknown and the incidence is stated to be 1%, although more recent data suggest that it is higher. The symptoms are penile deviation and painful erection in association with penile plaques. The diagnosis is performed by palpation of the pen...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-004-0424-x
更新日期：2004-11-01 00:00:00
abstract：PURPOSE:We investigated hemodynamics in patients receiving delta-Aminolevulinic acid (delta-ALA) to visualize tumor margins prior to radical retro pubic prostatectomy. PATIENTS:Twenty patients undergoing elective open radical retro pubic prostatectomy (RRP). METHODS:Cohort observational study. Ten patients receiving ...
journal_title：World journal of urology
pub_type： 临床试验,杂志文章
doi：10.1007/s00345-011-0788-7
更新日期：2013-04-01 00:00:00
abstract：PURPOSE:Current systemic treatment of targeted therapies, namely the vascular endothelial growth factor-antibody (VEGF-AB), VEGF receptor tyrosine kinase inhibitor (TKI) and mammalian target of rapamycin (mTOR) inhibitors, have improved progression-free survival and replaced non-specific immunotherapy with cytokines in...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-016-1868-5
更新日期：2017-02-01 00:00:00
abstract：PURPOSE:Clinical outcomes prognostic markers are awaited in clear-cell renal carcinoma (ccRCC) to improve patient-tailored management and to assess six different markers' influence on clinical outcomes from ccRCC specimen and their incremental value combined with TNM staging. MATERIALS AND METHODS:This is a retrospect...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-016-1854-y
更新日期：2017-01-01 00:00:00
abstract：:We are fortunate that our ability to diagnose the specific adrenal entities that mandate a surgical approach is extremely accurate. The combination of analytical methodology to measure the appropriate adrenocortical and medullary hormone production and the radiology techniques for localization are superb. The manageme...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s003450050103
更新日期：1999-02-01 00:00:00
abstract：OBJECTIVES:To understand how prioritization of treatment attributes and treatment choice varies by patient characteristics, we sought to specifically determine how demographic variables affect patient treatment preference. PATIENTS AND METHODS:Male patients with urethral stricture disease participated in a choice-base...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-017-2066-9
更新日期：2017-11-01 00:00:00
abstract：OBJECTIVES:To evaluate the diagnostic value of 12 core biopsy versus sextant biopsy at different prostatic-specific antigen densities (PSAD). METHODS:We retrospectively analyzed the records of 1,463 patients who underwent transrectal ultrasound-guided prostate biopsies at our institution. 995 patients underwent 12 cor...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-008-0264-1
更新日期：2008-08-01 00:00:00
abstract：PURPOSE:We sought the association of preoperative serum total testosterone (tT), hypogonadism, 17β estradiol (E2), and sex hormone-binding globulin (SHBG) with early biochemical recurrence (BCR) after radical prostatectomy (RP). METHODS:Sex steroids were assessed the day before surgery (7-11 a.m.) in a cohort of 605 p...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-012-0856-7
更新日期：2013-04-01 00:00:00
abstract：OBJECTIVES:Androgen receptor (AR) action in benign and malignant tissue is potentiated by a number of co-regulatory proteins that may interact with one or more receptor domains. With improvement of research methodologies, it became possible to detect a number of co-activators whose expression is increased in prostate c...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-011-0797-6
更新日期：2012-06-01 00:00:00
abstract：PURPOSE:To review the etiology and pathogenesis of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). METHODS:A literature review for the years 1985-2012 was performed using the MEDLINE database of the United States National Library of Medicine. RESULTS:The evidence for ongoing infection in men with CP/CPPS ...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-013-1061-z
更新日期：2013-08-01 00:00:00
abstract：PURPOSE:To compare long-term functional outcomes after robotic vs. retropubic RP for patients with localized prostate cancer in routine care. METHODS:"HAROW" was a large German noninterventional health services research study that prospectively evaluated the treatment of patients with localized prostate cancer (≤ T2c)...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-02956-8
更新日期：2020-07-01 00:00:00
abstract：INTRODUCTION:Concomitant anti-incontinence surgery at the time of prolapse repair has been a long-debated topic. Still today, there remains no clear answer to this question, although in recent years the literature has become more robust with the addition of more randomized controlled trials. The lifetime risk for women...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-015-1591-7
更新日期：2015-09-01 00:00:00
abstract：:The most important phosphates involved in urinary stone disease are carbonate apatite, brushite, and struvite. Overall, phosphate stones account for 12-20% of all stones, with a downward trend for struvite and an increase in carbonate apatite being observed in the last decade. The physicochemical basis for the formati...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s003450050152
更新日期：1999-10-01 00:00:00
