Abstract:
:Evidence from familial and genetic association studies have reported that DNA sequence variants play an important role, together with non-genetic factors, in the aetiology of both exercise-associated and occupational-associated acute and chronic musculoskeletal soft tissue injuries. The associated variants, which have been identified to date, may contribute to the interindividual variation in the structure and, by implication, mechanical properties of the collagen fibril and surrounding matrix within musculoskeletal soft tissues, as well as their response to mechanical loading and other stimuli. Future work should focus on the establishment of multidisciplinary international consortia for the identification of biologically relevant variants involved in modulating injury risk. These consortia will improve the limitations of the published hypothesis-driven genetic association studies, since they will allow resources to be pooled in recruiting large well-characterised cohorts required for whole-genome screening. Finally, clinicians and coaches need to be aware that many direct-to-consumer companies are currently marketing genetic tests directly to athletes without it being requested by an appropriately qualified healthcare professional, and without interpretation alongside other clinical indicators or lifestyle factors. These specific genetic tests are premature and are not necessarily required to evaluate susceptibility to musculoskeletal soft tissue injury. Current practice should rather consider susceptibility through known risk factors such as a positive family history of a specific injury, a history of other tendon and/or ligament injuries and participation in activities associated with the specific musculoskeletal injuries. Potential susceptible athletes may then be individually managed to reduce their risk profile.
journal_name
Br J Sports Medjournal_title
British journal of sports medicineauthors
Collins M,September AV,Posthumus Mdoi
10.1136/bjsports-2015-095180subject
Has Abstractpub_date
2015-12-01 00:00:00pages
1497-503issue
23eissn
0306-3674issn
1473-0480pii
bjsports-2015-095180journal_volume
49pub_type
杂志文章,评审abstract::Data for the age of menarche have been collected on 98 female volleyball players and 75 basketball players. The players belonged to four different levels of competition: international, national, intervarsity and district. Menarche is significantly delayed in players as compared with the controls. There is a continuous...
journal_title:British journal of sports medicine
pub_type: 杂志文章
doi:10.1136/bjsm.23.4.237
更新日期:1989-12-01 00:00:00
abstract::The most commonly reported injury site in rowers is the lower back. Research in recent years has focused on epidemiology and biomechanical analyses to try and understand mechanisms that contribute to this injury's onset. Injury surveillance mainly comprises retrospective questionnaires and reviews of medical records w...
journal_title:British journal of sports medicine
pub_type: 杂志文章,评审
doi:10.1136/bjsports-2014-093968
更新日期:2014-11-01 00:00:00
abstract::There is little information on the nutritional habits of female football players at any level of the game. There is also a shortage of information on the nutrition and hydration strategies that players should adopt. In general, differences in nutritional needs between males and females are smaller than differences bet...
journal_title:British journal of sports medicine
pub_type: 杂志文章,评审
doi:10.1136/bjsm.2007.036475
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND:The accurate measurement of physical activity is crucial to understanding the relationship between physical activity and disease prevention and treatment. OBJECTIVE:The primary purpose of this study was to investigate the validity and reliability of the activPAL physical activity monitor in measuring step n...
journal_title:British journal of sports medicine
pub_type: 杂志文章
doi:10.1136/bjsm.2006.027276
更新日期:2006-09-01 00:00:00
abstract::Editorial Note As discussed in a recent editorial, the British Journal of Sports Medicine (BJSM) rescinds the Expression of Concern [1] for a recent network meta-analysis (NMA) [2] that was issued solely on the basis of comments by Professor Maher and colleagues [3]. The original authors (Dr Belavy and colleagues) hav...
journal_title:British journal of sports medicine
pub_type: 杂志文章
doi:10.1136/bjsports-2019-100886eoc1
更新日期:2020-09-03 00:00:00
abstract:OBJECTIVE:Several stressors such as cold water immersion, hyperoxic exposure and decompression-induced circulating bubbles can alter arterial circulation after a dive. The aim of this study was to investigate the arterial modifications induced by a specific diving training including repeated hyperbaric exposures and ph...
journal_title:British journal of sports medicine
pub_type: 杂志文章
doi:10.1136/bjsm.2007.043364
更新日期:2009-07-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 临床试验,杂志文章
doi:10.1136/bjsm.30.3.243
更新日期:1996-09-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of varying interdental bite platform thickness of the scuba mouthpiece on airway efficiency. METHODS:10 male divers had their mean peak flow measured for free breathing, maximum flow with diving mouthpiece, teeth in occlusion, and for five experimental mouthpieces with different thi...
journal_title:British journal of sports medicine
pub_type: 杂志文章
doi:10.1136/bjsm.30.2.145
更新日期:1996-06-01 00:00:00
abstract:AIM:To investigate the effect of task familiarisation on the spontaneous pattern of energy expenditure during a series of 2000 m cycling time trials (TTs). METHOD:Nine trained males completed three 2000 m TTs on a Velotron cycling ergometer. To examine pacing strategy, the data were assigned to 250 m "bins," with the ...
journal_title:British journal of sports medicine
pub_type: 杂志文章
doi:10.1136/bjsm.2008.056416
更新日期:2009-10-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章
doi:10.1136/bjsm.2005.019026
更新日期:2006-01-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章,评审
doi:10.1136/bjsports-2011-090190
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVES:To study the long term effect of tibial shaft fractures treated by immobilisation in a long leg cast on the calf muscle bulk. METHODS:Computed tomography scans were performed at fixed points on the lower legs of 23 non-professional athletes who sustained closed tibial fractures 16 years previously. Length o...
journal_title:British journal of sports medicine
pub_type: 杂志文章
doi:10.1136/bjsm.2005.020743
更新日期:2006-06-01 00:00:00
abstract:AIM:To compare surgical and conservative treatment for high-risk stress fractures of the anterior tibial cortex, navicular and proximal fifth metatarsal. METHODS:Systematic searches of CENTRAL, MEDLINE, EMBASE, CINAHL, SPORTDiscus and PEDro were performed to identify relevant prospective and retrospective studies. Two...
journal_title:British journal of sports medicine
pub_type: 杂志文章,评审
doi:10.1136/bjsports-2013-093246
更新日期:2015-03-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章
doi:10.1136/bjsm.2003.004838
更新日期:2004-12-01 00:00:00
abstract::Jet lag is often cited as a cause of poor sporting performance. We report on the case of a rugby league player who flew 20,000 km and 12 time zones, then repeated the feat a few days later, prior to playing with distinction in an important final match in an international series. ...
journal_title:British journal of sports medicine
pub_type: 杂志文章
doi:10.1136/bjsm.2006.034066
更新日期:2007-06-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章
doi:10.1136/bjsm.2007.037804
更新日期:2007-08-01 00:00:00
abstract:AIM:To describe the epidemiology of National Collegiate Athletic Association (NCAA) men's and women's soccer injuries during the 2009/2010-2014/2015 academic years. METHODS:This descriptive epidemiology study used NCAA Injury Surveillance Program (NCAA-ISP) data during the 2009/2010-2014/2015 academic years, from 44 m...
journal_title:British journal of sports medicine
pub_type: 杂志文章
doi:10.1136/bjsports-2015-095718
更新日期:2017-07-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章
doi:10.1136/bjsm.17.1.16
更新日期:1983-03-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章
doi:10.1136/bjsports-2016-096236
更新日期:2018-10-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章
doi:10.1136/bjsm.2004.012732
更新日期:2005-04-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章
doi:10.1136/bjsm.2007.044818
更新日期:2009-05-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章,评审
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更新日期:2015-05-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章
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更新日期:2003-04-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 临床试验,杂志文章
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更新日期:2007-08-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章,评审
doi:10.1136/bjsm.2009.064139
更新日期:2010-04-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章,meta分析,评审
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更新日期:2018-04-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章,评审
doi:10.1136/bjsports-2012-092078
更新日期:2014-04-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章
doi:10.1136/bjsm.2009.070128
更新日期:2010-07-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章
doi:10.1136/bjsm.2010.081836
更新日期:2012-05-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章,评审
doi:10.1136/bjsm.2008.054874
更新日期:2009-09-01 00:00:00