Ezh2 is involved in radial neuronal migration through regulating Reelin expression in cerebral cortex.

abstract：:The clinical application of dihydroartemisinin (DHA) has been hampered due to its poor water-solubility. To overcome this hurdle, we devised a novel polymer-drug conjugate, multiarm polyethylene glycol-dihydroartemisinin (PEG-DHA), made by linking DHA with multiarm polyethylene glycol. Herein, we investigated PEG-DHA ...

journal_title：Scientific reports

authors： Dai L,Wang L,Deng L,Liu J,Lei J,Li D,He J

更新日期：2014-07-29 00:00:00

abstract：:Geometric frustration, in which competing interactions give rise to degenerate ground states, potentially induces various exotic quantum phenomena in magnetic materials. Minimal models comprising triangular units, such as triangular and Kagome lattices, have been investigated for decades to realize novel quantum phase...

journal_title：Scientific reports

authors： Yamaguchi H,Okubo T,Kittaka S,Sakakibara T,Araki K,Iwase K,Amaya N,Ono T,Hosokoshi Y

更新日期：2015-10-15 00:00:00

abstract：:Gut microbiota mediated low-grade inflammation is involved in the onset of type 2 diabetes (T2DM). In this study, we used a high fat sucrose (HFS) diet-induced pre-insulin resistance and a low dose-STZ HFS rat models to study the effect and mechanism of Lactobacillus casei Zhang in protecting against T2DM onset. Hyper...

journal_title：Scientific reports

authors： Zhang Y,Guo X,Guo J,He Q,Li H,Song Y,Zhang H

更新日期：2014-07-18 00:00:00

abstract：:Lower corrected calcium (cCa) levels are associated with a better prognosis among incident dialysis patients. However, cCa frequently overestimates ionized calcium (iCa) levels. The prognostic importance of the true calcium status defined by iCa remains to be revealed. We conducted a retrospective cohort study of inci...

journal_title：Scientific reports

authors： Yamaguchi S,Hamano T,Doi Y,Oka T,Kajimoto S,Kubota K,Yasuda S,Shimada K,Matsumoto A,Hashimoto N,Sakaguchi Y,Matsui I,Isaka Y

更新日期：2020-03-10 00:00:00

abstract：:In the present study rice straw (R, control) was mixed with Cowdung (C), Azolla (A) and cellulolytic fungus Aspergillus terreus (F) in different combinations viz. RC, RA, RF, RCF, RCA, RFA and RCFA and subjected to aerobic composting (Acom) and vermicomposting (Vcom - with Eisenia fetida). It was found that addition o...

journal_title：Scientific reports

authors： Arora M,Kaur A

更新日期：2019-02-04 00:00:00

abstract：:The human brain is lateralised to the right for visuospatial attention, particularly when reorienting attention to unexpected stimuli. However, the developmental characteristics of lateralisation remain unclear. To address this question, we devised a saccade task applicable for both adults and children. To assess the ...

journal_title：Scientific reports

authors： Sanefuji M,Yamashita H,Torio M,Katsuki D,Akamine S,Ishizaki Y,Kishimoto J,Sakai Y,Takada H,Yoshida K,Ohga S

更新日期：2018-05-15 00:00:00

abstract：:Ubiquitous in nature, polyamines (PAs) are a class of low-molecular aliphatic amines critically involved in cell growth, survival and differentiation. The polycation behavior is validated as a successful strategy in delivery systems to enhance oligonucleotide loading and cellular uptake. In this study, the chemical fe...

journal_title：Scientific reports

authors： Della Rosa G,Di Corato R,Carpi S,Polini B,Taurino A,Tedeschi L,Nieri P,Rinaldi R,Aloisi A

更新日期：2020-12-03 00:00:00

abstract：:The biochemical abnormalities and oxidative stress during pathogenesis of hepatic fibrosis could lead to alteration of trace elements. We studied the alteration of major trace elements during the pathogenesis of N-nitrosodimethylamine (NDMA)-induced hepatic fibrosis in rats. The biochemical and pathological indices of...

journal_title：Scientific reports

authors： George J,Tsutsumi M,Tsuchishima M

更新日期：2019-01-24 00:00:00

abstract：:Animals that experience situations likely to induce negative emotions show changes in judgment associated with pessimism. Few studies have focused on whether animals express stable differences in pessimism and whether these differences are related to personality traits. The first aim of this study was to explore if da...

journal_title：Scientific reports

authors： Lecorps B,Weary DM,von Keyserlingk MAG

更新日期：2018-01-23 00:00:00

abstract：:The way teeth grow is recorded in dental enamel as incremental marks. Detailed analysis of tooth growth is known to provide valuable insights into the growth and the pace of life of vertebrates. Here, we study the growth pattern of the first lower molar in several extant and extinct species of Equus and explore its re...

journal_title：Scientific reports

authors： Nacarino-Meneses C,Jordana X,Orlandi-Oliveras G,Köhler M

更新日期：2017-11-21 00:00:00

abstract：:Utilization of computational approach in the study of social behaviour of animals is increasing and we attempted such an approach in our study of tree-dwelling bats. These bats live in highly dynamic fission-fusion societies that share multiple roosts in a common home range. The key behavioural component associated wi...

journal_title：Scientific reports

authors： Zelenka J,Kasanický T,Budinská I,Kaňuch P

更新日期：2020-10-08 00:00:00

abstract：:Much uncertainty exists about the history of the Greenland Ice Sheet (GIS), particularly as to the frequency of extreme shelf edge glaciations. Because the last glaciation removed most of the record of earlier GIS extent on land and shelf exploration of the older GIS glacial record requires the use of deeper marine ar...

journal_title：Scientific reports

authors： Nielsen T,Kuijpers A

更新日期：2013-01-01 00:00:00

abstract：:Efficient isolation and genetic analysis of circulating tumor cells (CTCs) from cancer patients' blood is a critical step for clinical applications using CTCs. Here, we report a novel CTC-isolation method and subsequent genetic analysis. CTCs from the blood were complexed with magnetic beads coated with antibodies aga...

journal_title：Scientific reports

authors： Yoo CE,Park JM,Moon HS,Joung JG,Son DS,Jeon HJ,Kim YJ,Han KY,Sun JM,Park K,Park D,Park WY

更新日期：2016-11-28 00:00:00

abstract：:To investigate the safety and efficiency of using robotic staplers for intracorporeal gastroduodenostomy in reduced-port robotic gastrectomy for gastric adenocarcinoma. We retrospectively reviewed patients who underwent totally robotic and laparoscopic gastrectomy with intracorporeal gastroduodenostomy. Gastroduodenos...

journal_title：Scientific reports

authors： Kim JS,Batajoo H,Son T,Choi S,Seo WJ,Cho M,Kim YM,Lee JH,Kim HI,Hyung WJ

更新日期：2020-09-07 00:00:00

abstract：:Heavy metals are environmental pollutants affect the integrity and distribution of living organisms in the ecosystem and also humans across the food chain. The study targeted the removal of copper (Cu2+) from aqueous solutions, depending on the biosorption process. The bacterial candidate was identified using 16S rRNA...

journal_title：Scientific reports

authors： Ghoniem AA,El-Naggar NE,Saber WIA,El-Hersh MS,El-Khateeb AY

更新日期：2020-06-11 00:00:00

abstract：:Gene targeting in embryonic stem cells (ESCs) has become the principal technology for generating knockout models. Although numerous studies have predicted that the disruption of p53 leads to increased developmental anomalies and malignancies, most p53 knockout mice develop normally. Therefore, the role of p53 in anima...

journal_title：Scientific reports

authors： Kawamata M,Ochiya T

更新日期：2012-01-01 00:00:00

abstract：:In this paper we report a low complexity compression method that is suitable for compact optical scanning holography (OSH) systems with different optical settings. Our proposed method can be divided into 2 major parts. First, an automatic decision maker is applied to select the rows of holographic pixels to be scanned...

journal_title：Scientific reports

authors： Tsang PW,Poon TC,Liu JP,Kim T,Kim YS

更新日期：2016-10-06 00:00:00

abstract：:Developing rationally controlled bottom-up device fabrication processes is essential for the achievement of high performance optimal devices. We report a controlled, seedless and site-selective hydrothermal technique to fabricate high-performance nanostructured ZnO UV-detectors directly on-chip. We demonstrate that by...

journal_title：Scientific reports

authors： Alenezi MR,Henley SJ,Silva SR

更新日期：2015-02-17 00:00:00

abstract：:Leaf functional traits have attracted the attention of ecologists for several decades, but few studies have systematically assessed leaf morphological traits (termed "economic traits"), stomatal (termed "hydraulic"), and anatomical traits of entire forest communities, thus it is unclear whether their relationships are...

journal_title：Scientific reports

authors： Liu C,Li Y,Xu L,Chen Z,He N

更新日期：2019-04-09 00:00:00

abstract：:Ultrasound-enhanced drug delivery has shown great promise in providing targeted burst release of drug at the site of the disease. Yet current solid ultrasound-responsive particles are non-degradable with limited potential for drug-loading. Here, we report on an ultrasound-responsive multi-cavity poly(lactic-co-glycoli...

journal_title：Scientific reports

authors： Su X,Thomas RG,Bharatula LD,Kwan JJ

更新日期：2019-07-03 00:00:00

abstract：:Hearing loss becomes increasingly common with age and affects quality of life. Recently, scientists have published articles about the relationship between metabolic disease and hearing loss. Metabolic disease was previously found to be highly related to an increase in alkaline phosphatase. Thus, there may be an indire...

journal_title：Scientific reports

authors： Lim ZW,Chen WL

更新日期：2020-03-04 00:00:00

abstract：:Maintaining energy balance over a wide range of temperatures is critical for an active pelagic fish species such as the mahi-mahi (Coryphaena hippurus), which can experience rapid changes in temperature during vertical migrations. Due to the profound effect of temperature on mitochondrial function, this study was desi...

journal_title：Scientific reports

authors： Lau GY,Cox GK,Stieglitz JD,Benetti DD,Grosell M

更新日期：2020-09-10 00:00:00

abstract：:Iron oxide nanoparticles have attracted a great deal of research interest and have been widely used in bioscience and clinical research including as contrast agents for magnetic resonance imaging, hyperthermia and magnetic field assisted radionuclide therapy. It is therefore important to develop methods, which can pro...

journal_title：Scientific reports

authors： Erofeev A,Gorelkin P,Garanina A,Alova A,Efremova M,Vorobyeva N,Edwards C,Korchev Y,Majouga A

更新日期：2018-05-10 00:00:00

abstract：:Methamphetamine (Meth) is one of the most frequently abused drugs worldwide. Recent studies have indicated that antibodies with high affinity for Meth reduce its pharmacological effects. The purpose of this study was to develop a technique for virus-based passive immunization against Meth effects. We generated a recom...

journal_title：Scientific reports

authors： Chen YH,Wu KJ,Wu KL,Wu KL,Tsai HM,Chen ML,Chen YW,Hsieh W,Lin CM,Wang Y

更新日期：2017-04-07 00:00:00

abstract：:Plasmonics is a rapidly emerging platform for quantum state engineering with the potential for building ultra-compact and hybrid optoelectronic devices. Recent experiments have shown that despite the presence of decoherence and loss, photon statistics and entanglement can be preserved in single plasmonic systems. This...

journal_title：Scientific reports

authors： Asano M,Bechu M,Tame M,Kaya Özdemir Ş,Ikuta R,Güney DÖ,Yamamoto T,Yang L,Wegener M,Imoto N

更新日期：2015-12-16 00:00:00

abstract：:Golden snub-nosed monkey (Rhinopithecus roxellana) is one of the most endangered primate species found in China, exhibiting multilevel society consisting of several one-male-females together with their offspring units (OMU), and all-male units (AMU). Female dispersal patterns of the species within herd have been well ...

journal_title：Scientific reports

authors： Huang ZP,Bian K,Liu Y,Pan RL,Qi XG,Li BG

更新日期：2017-05-11 00:00:00

abstract：:Lung cancer represents a major cause of cancer-related death worldwide. Although various tactics and anti-tumor drugs have been used to improve curative effects, five-year survival rate of lung cancer patients remains poor. In this study, we investigated the action and underlying mechanisms of our recently optimized C...

journal_title：Scientific reports

authors： Zheng T,Que Z,Jiao L,Kang Y,Gong Y,Yao J,Ma C,Bi L,Dong Q,Zhao X,Xu L

更新日期：2017-07-10 00:00:00

abstract：:Selective filtration of gas, water, and liquid or gaseous oil is essential to prevent possible environmental pollution and machine/facility malfunction in oil-based industries. Novel materials and structures able to selectively and efficiently filter liquid and vapor in various types of solutions are therefore in cont...

journal_title：Scientific reports

authors： Bong J,Lim T,Seo K,Kwon CA,Park JH,Kwak SK,Ju S

更新日期：2015-09-23 00:00:00

abstract：:Pectins, the major components of cell walls in plants, are synthesized and secreted to cell walls as highly methyl-esterified polymers and then demethyl-esterified by pectin methylesterases (PMEs). The PMEs are spatially regulated by pectin methylesterase inhibitors (PMEIs). In this study, 43 and 49 putative PME and P...

journal_title：Scientific reports

authors： Zhang P,Wang H,Qin X,Chen K,Zhao J,Zhao Y,Yue B

更新日期：2019-12-27 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDAC) patients have poor prognosis and poor response to treatment. This is largely due to PDAC being associated with a dense and active stroma and tumor fibrosis (desmoplasia). Desmoplasia is characterized by excessive degradation and formation of the extracellular matrix (ECM) genera...

journal_title：Scientific reports

authors： Willumsen N,Ali SM,Leitzel K,Drabick JJ,Yee N,Polimera HV,Nagabhairu V,Krecko L,Ali A,Maddukuri A,Moku P,Ali A,Poulose J,Menon H,Pancholy N,Costa L,Karsdal MA,Lipton A

更新日期：2019-12-24 00:00:00