Abstract：
:Recent stroke studies have shown that the ipsi-lesional thalamus longitudinally and significantly decreases after stroke in the acute and subacute stages. However, additional considerations in the chronic stages of stroke require exploration including time since stroke, gender, intracortical volume, aging, and lesion volume to better characterize thalamic differences after cortical infarct. This cross-sectional retrospective study quantified the ipsilesional and contralesional thalamus volume from 69 chronic stroke subjects' anatomical MRI data (age 35-92) and related the thalamus volume to time since stroke, gender, intracortical volume, age, and lesion volume. The ipsi-lesional thalamus volume was significantly smaller than the contra-lesional thalamus volume (t(68) = 13.89, p < 0.0001). In the ipsilesional thalamus, significant effect for intracortical volume (t(68) = 2.76, p = 0.008), age (t(68) = 2.47, p = 0.02), lesion volume (t(68) = - 3.54, p = 0.0008), and age*time since stroke (t(68) = 2.46, p = 0.02) were identified. In the contralesional thalamus, significant effect for intracortical volume (t(68) = 3.2, p = 0.002) and age (t = - 3.17, p = 0.002) were identified. Clinical factors age and intracortical volume influence both ipsi- and contralesional thalamus volume and lesion volume influences the ipsilesional thalamus. Due to the cross-sectional nature of this study, additional research is warranted to understand differences in the neural circuitry and subsequent influence on volumetrics after stroke.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Krishnamurthy LC,Champion GN,McGregor KM,Krishnamurthy V,Turabi A,Roberts SR,Nocera JR,Borich MR,Rodriguez AD,Belagaje SR,Harrington RM,Harris-Love ML,Harnish SM,Drucker JH,Benjamin M,Meadows ML,Seeds L,Zlatar ZZ,Sudhdoi
10.1038/s41598-020-76382-xsubject
Has Abstractpub_date
2020-11-24 00:00:00pages
20488issue
1issn
2045-2322pii
10.1038/s41598-020-76382-xjournal_volume
10pub_type
杂志文章abstract：:Bats of the Rhinolophidae and Hipposideridae families, and Pteronotus parnellii, compensate for Doppler shifts generated by their own flight movement. They adjust their call frequency such that the frequency of echoes coming from ahead fall in a specialized frequency range of the hearing system, the auditory fovea, to...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-22880-y
更新日期：2018-03-15 00:00:00
abstract：:Programmed cell death 5 (PDCD5) is believed to play a crucial role in p53 activation; however, the underlying mechanism of how PDCD5 function is regulated during apoptosis remains obscure. Here, we report that the serine/threonine phosphatase PPEF-1 interacts with and dephosphorylates PDCD5 at Ser-119, which leads to ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep39222
更新日期：2017-01-04 00:00:00
abstract：:Plasmonics is a rapidly emerging platform for quantum state engineering with the potential for building ultra-compact and hybrid optoelectronic devices. Recent experiments have shown that despite the presence of decoherence and loss, photon statistics and entanglement can be preserved in single plasmonic systems. This...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep18313
更新日期：2015-12-16 00:00:00
abstract：:To report the efficacy and safety of large diameter scleral lenses and determine their suitability in Asian subjects with intractable ocular surface diseases. This prospective study enrolled intractable ocular surface diseases subjects with uncorrected visual acuity > counting finger but ≥ 0.3 logMAR and best-correcte...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-021-82010-z
更新日期：2021-01-27 00:00:00
abstract：:In recent years it has been shown that the therapeutic benefits of human mesenchymal stem/stromal cells (hMSCs) in the Central Nervous System (CNS) are mainly attributed to their secretome. The implementation of computer-controlled suspension bioreactors has shown to be a viable route for the expansion of these cells ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep27791
更新日期：2016-06-15 00:00:00
abstract：:Au nanoparticles (AuNPs), which easily aggregate in organic thin film, are observed to well-disperse in chicken albumen thin films. The incorporated AuNPs is distributed uniformly inside the thin film and is as dense as 650 (particles/μm(3)). In addition, enhanced ultraviolet (UV) fluorescence centered at 350 nm is ob...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep01505
更新日期：2013-01-01 00:00:00
abstract：:End stage renal disease (ESRD) patients depend on hemodialysis (HD) as a life-sustaining treatment, but HD membrane properties play a critical role in blood activation during HD and can lead to severe patient outcomes. This study reports on a series of investigations on the common clinical HD membranes available in Ca...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-71755-8
更新日期：2020-09-09 00:00:00
abstract：:Single-walled carbon nanotubes (SWCNTs) have been modified with ester groups using typical organic radical chemistry. Consequently, traps for mobile excitons have been created, which enhanced the optical properties of the material. The proposed methodology combines the benefits of mainstream approaches to create lumin...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76716-9
更新日期：2020-11-16 00:00:00
abstract：:The connection between structure and stability of ecological networks has been widely studied in the last fifty years. A challenge that scientists continue to face is that in-depth mathematical model analysis is often difficult, unless the considered systems are specifically constrained. This makes it challenging to g...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-50373-z
更新日期：2019-10-01 00:00:00
abstract：:The advent of flexible optoelectronic devices has accelerated the development of semiconducting polymeric materials. We seek to replace conventional expensive semiconducting photodetector materials with our cost-effective composite system. We demonstrate in this work the successful fabrication of a photoconductive com...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep16761
更新日期：2015-11-16 00:00:00
abstract：:A binary metallic superoscillatory lens assisted with annular subwavelength slits is proposed, which generates a longitudinally-polarized super-resolution focal point. The annular slits are designed to selectively transmit radially-polarized light. Simulations using the finite element method show a 0.24 λ focal spot w...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-56810-3
更新日期：2020-01-28 00:00:00
abstract：:Non-invasive investigation of physiological changes and metabolic events associated with brain activity in mice constitutes a major challenge. Conventionally, fMRI assesses neuronal activity by evaluating activity-evoked local changes in blood oxygenation levels (BOLD). In isoflurane-anaethetized mice, however, we fou...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-46477-1
更新日期：2019-07-22 00:00:00
abstract：:The misuse of pharmaceutical opioids is a major public health issue. In Australia, codeine was re-scheduled on 1 February 2018 to restrict access; it is now only available on prescription. The aim of this study was to measure the change in dental opioid prescriptions, one year before and after the codeine re-schedulin...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-65390-6
更新日期：2020-05-21 00:00:00
abstract：:Effective promotion of air filtration applications proposed for fibers requires their real nanoscale diameter, optimized pore structure, and high service strength; however, creating such filter medium has proved to be a tremendous challenge. This study first establishes a strategy to design and fabricate novel poly(m-...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep40550
更新日期：2017-01-11 00:00:00
abstract：:Compact silicon integrated lasers are of significant interest for various applications. We present a detailed investigation for realizing sub-mm long on-chip laser structures operating at λ = 1.533 µm on the silicon-on-insulator photonic platform by combining a multi-segment silicon waveguide structure and a recently ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-67722-y
更新日期：2020-07-02 00:00:00
abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-018-29057-7
更新日期：2018-07-20 00:00:00
abstract：:Probing the oligomeric state of abundant molecules, such as membrane proteins in intact cells, is essential, but has not been straightforward. We address this challenge with a simple counting strategy that is capable of reporting the oligomeric state of dense, membrane-bound protein complexes. It is based on single-mo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep14072
更新日期：2015-09-11 00:00:00
abstract：:In this paper, we propose an angle- and polarization-insensitive metamaterial absorber. We design a metamaterial unit cell that is based on a split ring cross resonator (SRCR). We observe that the absorption frequency and absorption ratio are insensitive to incident angles when a via array surrounds the SRR. We demons...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep39686
更新日期：2016-12-21 00:00:00
abstract：:Immune-evasion and immune checkpoints are promising new therapeutic targets for several cancer entities. In ovarian cancer, the clinical role of programmed cell death receptor ligand 1 (PD-L1) expression as mechanism to escape immune recognition has not been clarified yet. We analyzed PD-L1 expression of primary ovari...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep42929
更新日期：2017-03-07 00:00:00
abstract：:Natural variability in pH in the diffusive boundary layer (DBL), the discrete layer of seawater between bulk seawater and the outer surface of organisms, could be an important factor determining the response of corals and coralline algae to ocean acidification (OA). Here, two corals with different morphologies and one...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-49044-w
更新日期：2019-09-06 00:00:00
abstract：:We study the dynamics of an ultrafast single photon pulse in a one-dimensional waveguide two-point coupled with a Jaynes-Cummings system. We find that for any single photon input the transmissivity depends periodically on the separation between the two coupling points. For a pulse containing many plane wave components...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep33867
更新日期：2016-09-22 00:00:00
abstract：:Lipid droplet (LD)-associated hydrolase (LDAH) is a newly identified LD protein abundantly expressed in tissues that predominantly store triacylglycerol (TAG). However, how LDAH regulates TAG metabolism remains unknown. We found that upon oleic acid loading LDAH translocalizes from the ER to newly formed LDs, and indu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-02963-y
更新日期：2017-06-02 00:00:00
abstract：:Transient ischemia produces postischemic tingling sensation. Ischemia also produces nerve conduction block that may modulate spinal neural circuits. In the present study, reduced mechanical thresholds for hindpaw-withdrawal reflex were found in mice after transient hindpaw ischemia, which was produced by a high pressu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep11191
更新日期：2015-07-13 00:00:00
abstract：:Microbiome analysis using metagenomic sequencing has revealed a vast microbial diversity associated with plants. Identifying the molecular functions associated with microbiome-plant interaction is a significant challenge concerning the development of microbiome-derived technologies applied to agriculture. An alternati...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep29543
更新日期：2016-07-12 00:00:00
abstract：:This work focuses on the optimization of heterogeneous Fenton-like removal of organic pollutant (dye) from water using newly developed fibrous catalysts based on a full factorial experimental design. This study aims to approximate the feasibility of heterogeneous Fenton-like removal process and optionally make predict...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-72401-z
更新日期：2020-09-30 00:00:00
abstract：:The ongoing evolution of microbial pathogens represents a significant issue in diagnostic PCR/qPCR. Many assays are burdened with false negativity due to mispriming and/or probe-binding failures. Therefore, PCR/qPCR assays used in the laboratory should be periodically re-assessed in silico on public sequences to evalu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-37869-w
更新日期：2019-02-07 00:00:00
abstract：:An important safety concern on cell-based gene therapy is that few methods have been available to control the proliferation and functioning of therapeutic protein-expressing cells after transplantation. We previously reported that the proliferation and functioning of the cells transfected with herpes simplex virus thy...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-55269-6
更新日期：2019-12-11 00:00:00
abstract：:Juvenile hormone (JH) plays crucial roles in many aspects of the insect life. All the JH actions are initiated by transport of JH in the hemolymph as a complex with JH-binding protein (JHBP) to target tissues. Here, we report structural mechanism of JH delivery by JHBP based upon the crystal and solution structures of...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep00133
更新日期：2011-01-01 00:00:00
abstract：:Group A Streptococcus (GAS) secretes deoxyribonucleases and evades neutrophil extracellular killing by degrading neutrophil extracellular traps (NETs). However, limited information is currently available on the interaction between GAS and NETs in the pathogenicity of GAS pharyngitis. In this study, we modified a mouse...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-60306-w
更新日期：2020-02-24 00:00:00
abstract：:Individuals who are well integrated into society have greater access to resources and tend to live longer. Why some individuals are socially isolated and others are not is therefore puzzling from an evolutionary perspective. Answering this question requires establishing the mix of intrinsic and contextual factors that...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-18104-4
更新日期：2017-12-19 00:00:00
