Harnessing the landscape of microbial culture media to predict new organism-media pairings.

abstract：:The incidence of non-alcoholic fatty liver disease (NAFLD) increases with age. Cellular senescence refers to a state of irreversible cell-cycle arrest combined with the secretion of proinflammatory cytokines and mitochondrial dysfunction. Senescent cells contribute to age-related tissue degeneration. Here we show that...

journal_title：Nature communications

authors： Ogrodnik M,Miwa S,Tchkonia T,Tiniakos D,Wilson CL,Lahat A,Day CP,Burt A,Palmer A,Anstee QM,Grellscheid SN,Hoeijmakers JHJ,Barnhoorn S,Mann DA,Bird TG,Vermeij WP,Kirkland JL,Passos JF,von Zglinicki T,Jurk D

更新日期：2017-06-13 00:00:00

abstract：:Translatome reprogramming is a primary determinant of protein levels during stimuli adaptation. This raises the question: what are the translatome remodelers that reprogram protein output to activate biochemical adaptations. Here, we identify a translational pathway that represses metabolism to safeguard genome integr...

journal_title：Nature communications

authors： Balukoff NC,Ho JJD,Theodoridis PR,Wang M,Bokros M,Llanio LM,Krieger JR,Schatz JH,Lee S

更新日期：2020-11-13 00:00:00

abstract：:Global fish production (capture and aquaculture) has increased quickly, which has altered global flows of phosphorus (P). Here we show that in 2016, [Formula: see text] Tg P yr-1 (mean and interquartile range) was applied in aquaculture to increase fish production; while [Formula: see text] Tg P yr-1 was removed from ...

journal_title：Nature communications

authors： Huang Y,Ciais P,Goll DS,Sardans J,Peñuelas J,Cresto-Aleina F,Zhang H

更新日期：2020-01-17 00:00:00

abstract：:Quantum triangular-lattice antiferromagnets are important prototype systems to investigate numerous phenomena of the geometrical frustration in condensed matter. Apart from highly unusual magnetic properties, they possess a rich phase diagram (ranging from an unfrustrated square lattice to a quantum spin liquid), yet ...

journal_title：Nature communications

authors： Zvyagin SA,Graf D,Sakurai T,Kimura S,Nojiri H,Wosnitza J,Ohta H,Ono T,Tanaka H

更新日期：2019-03-06 00:00:00

abstract：:Amongst the many spectacular properties of hybrid lead halide perovskites, their defect tolerance is regarded as the key enabler for a spectrum of high-performance optoelectronic devices that propel perovskites to prominence. However, the plateauing efficiency enhancement of perovskite devices calls into question the ...

journal_title：Nature communications

authors： Righetto M,Lim SS,Giovanni D,Lim JWM,Zhang Q,Ramesh S,Tay YKE,Sum TC

更新日期：2020-06-01 00:00:00

abstract：:It is vital to design effective nitrogen fixation systems that operate under mild conditions, and to this end we recently reported an example of the catalytic formation of ammonia using a dinitrogen-bridged dimolybdenum complex bearing a pincer ligand, where up to twenty three equivalents of ammonia were produced base...

journal_title：Nature communications

authors： Tanaka H,Arashiba K,Kuriyama S,Sasada A,Nakajima K,Yoshizawa K,Nishibayashi Y

更新日期：2014-04-28 00:00:00

abstract：:Troodontid dinosaurs share a close ancestry with birds and were distributed widely across Laurasia during the Cretaceous. Hundreds of occurrences of troodontid bones, and their highly distinctive teeth, are known from North America, Europe and Asia. Thus far, however, they remain unknown from Gondwanan landmasses. Her...

journal_title：Nature communications

authors： Goswami A,Prasad GV,Verma O,Flynn JJ,Benson RB

更新日期：2013-01-01 00:00:00

abstract：:Biological cellular structures have inspired many scientific disciplines to design synthetic structures that can mimic their functions. Here, we closely emulate biological cellular structures in a rationally designed synthetic multicellular hybrid ion pump, composed of hydrogen-bonded [EMIM+][TFSI-] ion pairs on the s...

journal_title：Nature communications

authors： Amoli V,Kim JS,Jee E,Chung YS,Kim SY,Koo J,Choi H,Kim Y,Kim DH

更新日期：2019-09-05 00:00:00

abstract：:Stability is now a critical factor in the commercialization of organic photovoltaic (OPV) devices. Both extrinsic stability to oxygen and water and intrinsic stability to light and heat in inert conditions must be achieved. Triplet states are known to be problematic in both cases, leading to singlet oxygen production ...

journal_title：Nature communications

authors： Ramirez I,Privitera A,Karuthedath S,Jungbluth A,Benduhn J,Sperlich A,Spoltore D,Vandewal K,Laquai F,Riede M

更新日期：2021-01-20 00:00:00

abstract：:Hydrogen spillover phenomenon is well-documented in hydrogenation catalysis but still highly disputed in hydrogen storage. Until now, the existence of hydrogen spillover through metal-organic frameworks (MOFs) remains a topic of ongoing debate and how far the split hydrogen atoms diffuse in such materials is unknown. ...

journal_title：Nature communications

authors： Zhan G,Zeng HC

更新日期：2018-09-17 00:00:00

abstract：:Chemical clocks are often used as exciting classroom experiments, where an induction time is followed by rapidly changing colours that expose oscillating concentration patterns. This type of reaction belongs to a class of nonlinear chemical kinetics also linked to chaos, wave propagation and Turing patterns. Despite i...

journal_title：Nature communications

authors： Goesten MG,de Lange MF,Olivos-Suarez AI,Bavykina AV,Serra-Crespo P,Krywka C,Bickelhaupt FM,Kapteijn F,Gascon J

更新日期：2016-06-10 00:00:00

abstract：:The original version of this Article contained an error in the last sentence of the first paragraph of the Introduction and incorrectly read 'A proper electron beam control is one of the main challenges towards the Graal of developing a compact alternative of X-ray free-electron lasers by coupling LWFA gigaelectron-vo...

journal_title：Nature communications

authors： André T,Andriyash IA,Loulergue A,Labat M,Roussel E,Ghaith A,Khojoyan M,Thaury C,Valléau M,Briquez F,Marteau F,Tavakoli K,N'Gotta P,Dietrich Y,Lambert G,Malka V,Benabderrahmane C,Vétéran J,Chapuis L,El Ajjouri T,Se

更新日期：2018-05-02 00:00:00

abstract：:Genome replication is highly regulated in time and space, but the rules governing the remodeling of these programs during evolution remain largely unknown. We generated genome-wide replication timing profiles for ten Lachancea yeasts, covering a continuous evolutionary range from closely related to more divergent spec...

journal_title：Nature communications

authors： Agier N,Delmas S,Zhang Q,Fleiss A,Jaszczyszyn Y,van Dijk E,Thermes C,Weigt M,Cosentino-Lagomarsino M,Fischer G

更新日期：2018-06-06 00:00:00

abstract：:Although it has become increasingly clear that cancers display extensive cellular heterogeneity, the spatial growth dynamics of genetically distinct clones within developing solid tumours remain poorly understood. Here we leverage mosaic analysis with double markers (MADM) to trace subclonal populations retaining or l...

journal_title：Nature communications

authors： Muzumdar MD,Dorans KJ,Chung KM,Robbins R,Tammela T,Gocheva V,Li CM,Jacks T

更新日期：2016-09-02 00:00:00

abstract：:To cope with the global bacterial multidrug resistance, scientific communities have devoted significant efforts to develop novel antibiotics, particularly those with new modes of actions. Teixobactin, recently isolated from uncultured bacteria, is considered as a promising first-in-class drug candidate for clinical de...

journal_title：Nature communications

authors： Jin K,Sam IH,Po KHL,Lin D,Ghazvini Zadeh EH,Chen S,Yuan Y,Li X

更新日期：2016-08-03 00:00:00

abstract：:To date, the vast preponderance of somatic variants observed in the cancer genome have been rare variants, and it is common in practice to encounter in a new tumor variants that have not been observed previously. Here we focus on probability estimation for encountering such hitherto unseen variants. We draw upon stati...

journal_title：Nature communications

authors： Chakraborty S,Arora A,Begg CB,Shen R

更新日期：2019-12-03 00:00:00

abstract：:The extraction and combustion of fossil natural gas, consisting primarily of methane, generates vast amounts of greenhouse gases that contribute to climate change. However, as a result of recent research efforts, "solar methane" can now be produced through the photocatalytic conversion of carbon dioxide and water to m...

journal_title：Nature communications

authors： Ulmer U,Dingle T,Duchesne PN,Morris RH,Tavasoli A,Wood T,Ozin GA

更新日期：2019-07-18 00:00:00

abstract：:Pattern recognition underpins innate immunity; the accurate identification of danger, including infection, injury, or tumor, is key to an appropriately targeted immune response. Pathogen detection is increasingly well defined mechanistically, but the discrimination of endogenous inflammatory triggers remains unclear. ...

journal_title：Nature communications

authors： Zuliani-Alvarez L,Marzeda AM,Deligne C,Schwenzer A,McCann FE,Marsden BD,Piccinini AM,Midwood KS

更新日期：2017-11-17 00:00:00

abstract：:Non-line-of-sight (NLOS) imaging recovers objects using diffusely reflected indirect light using transient illumination devices in combination with a computational inverse method. While capture systems capable of collecting light from the entire NLOS relay surface can be much more light efficient than single pixel poi...

journal_title：Nature communications

authors： Liu X,Bauer S,Velten A

更新日期：2020-04-02 00:00:00

abstract：:Transition metal reagents and catalysts are generally effective to cleave all three bonds (one σ and two π) in a triple bond despite its high bonding energy. Recently, chemistry of single-bond cleavage by using main-group element compounds is rapidly being developed in the absence of transition metals. However, the cl...

journal_title：Nature communications

authors： Asakawa H,Lee KH,Lin Z,Yamashita M

更新日期：2014-06-26 00:00:00

abstract：:The mammary gland undergoes cycles of growth and regeneration throughout reproductive life, a process that requires mammary stem cells (MaSCs). Whilst recent genetic fate-mapping studies using lineage-specific promoters have provided valuable insights into the mammary epithelial hierarchy, the true differentiation pot...

journal_title：Nature communications

authors： Davis FM,Lloyd-Lewis B,Harris OB,Kozar S,Winton DJ,Muresan L,Watson CJ

更新日期：2016-10-25 00:00:00

abstract：:The Non-Proliferation Treaty and other non-proliferation agreements are in place worldwide to ensure that nuclear material and facilities are used only for peaceful purposes. Antineutrino detectors, sensitive to reactor power and fuel changes, can complement the tools already at the disposal of international agencies ...

journal_title：Nature communications

authors： Stewart C,Abou-Jaoude A,Erickson A

更新日期：2019-08-06 00:00:00

abstract：:Dysfunction of CD8+ T cells can lead to the development of chronic viral infection. Identifying mechanisms responsible for such T cell dysfunction is therefore of great importance to understand how to prevent persistent viral infection. Here we show using lymphocytic choriomeningitis virus (LCMV) infection that carcin...

journal_title：Nature communications

authors： Khairnar V,Duhan V,Patil AM,Zhou F,Bhat H,Thoens C,Sharma P,Adomati T,Friendrich SK,Bezgovsek J,Dreesen JD,Wennemuth G,Westendorf AM,Zelinskyy G,Dittmer U,Hardt C,Timm J,Göthert JR,Lang PA,Singer BB,Lang KS

更新日期：2018-07-02 00:00:00

abstract：:The number of human genomes being genotyped or sequenced increases exponentially and efficient haplotype estimation methods able to handle this amount of data are now required. Here we present a method, SHAPEIT4, which substantially improves upon other methods to process large genotype and high coverage sequencing dat...

journal_title：Nature communications

authors： Delaneau O,Zagury JF,Robinson MR,Marchini JL,Dermitzakis ET

更新日期：2019-11-28 00:00:00

abstract：:Sensitive detection of protein interactions and post-translational modifications of native proteins is a challenge for research and diagnostic purposes. A method for this, which could be used in point-of-care devices and high-throughput screening, should be reliable, cost effective and robust. To achieve this, here we...

journal_title：Nature communications

authors： Koos B,Cane G,Grannas K,Löf L,Arngården L,Heldin J,Clausson CM,Klaesson A,Hirvonen MK,de Oliveira FM,Talibov VO,Pham NT,Auer M,Danielson UH,Haybaeck J,Kamali-Moghaddam M,Söderberg O

更新日期：2015-06-12 00:00:00

abstract：:Cardiac voltage-gated sodium channels (Nav1.5) play an essential role in regulating cardiac electric activity by initiating and propagating action potentials in the heart. Altered Nav1.5 function is associated with multiple cardiac diseases including long-QT3 and Brugada syndrome. Here, we show that Nav1.5 is subject ...

journal_title：Nature communications

authors： Pei Z,Xiao Y,Meng J,Hudmon A,Cummins TR

更新日期：2016-06-23 00:00:00

abstract：:Acoustic sensors play an important role in many areas, such as homeland security, navigation, communication, health care and industry. However, the fundamental pressure detection limit hinders the performance of current acoustic sensing technologies. Here, through analytical, numerical and experimental studies, we sho...

journal_title：Nature communications

authors： Chen Y,Liu H,Reilly M,Bae H,Yu M

更新日期：2014-10-15 00:00:00

abstract：:Ions are ubiquitous biological regulators playing a key role for vital processes in animals and plants. The combined detection of ion concentration and real-time monitoring of small variations with respect to the resting conditions is a multiscale functionality providing important information on health states. This mu...

journal_title：Nature communications

authors： Romele P,Gkoupidenis P,Koutsouras DA,Lieberth K,Kovács-Vajna ZM,Blom PWM,Torricelli F

更新日期：2020-07-27 00:00:00

abstract：:The future of coastal wetlands and their ecological value depend on their capacity to adapt to the interacting effects of human impacts and sea-level rise. Even though extensive wetland loss due to submergence is a possible scenario, its magnitude is highly uncertain due to limited understanding of hydrodynamic and bi...

journal_title：Nature communications

authors： Rodríguez JF,Saco PM,Sandi S,Saintilan N,Riccardi G

更新日期：2017-07-13 00:00:00

abstract：:The sigma-2 receptor, whose gene remains to be cloned, has been validated as a biomarker for tumour cell proliferation. Here we report the use of a novel photoaffinity probe, WC-21, to identify the sigma-2 receptor-binding site. WC-21, a sigma-2 ligand containing both a photoactive azide moiety and a fluorescein isoth...

journal_title：Nature communications

authors： Xu J,Zeng C,Chu W,Pan F,Rothfuss JM,Zhang F,Tu Z,Zhou D,Zeng D,Vangveravong S,Johnston F,Spitzer D,Chang KC,Hotchkiss RS,Hawkins WG,Wheeler KT,Mach RH

更新日期：2011-07-05 00:00:00