Abstract:
QUESTION UNDER STUDY:What are the trends in avoidable cancer mortality in Switzerland and neighbouring countries? METHODS:Mortality data and population estimates 1996-2010 were obtained from the Swiss Federal Statistical Office for Switzerland and the World Health Organization Mortality Database (http://www.who.int/healthinfo/mortality_data/en/) for Austria, Germany, France and Italy. Age standardised mortality rates (ASMRs, European standard) per 100 000 person-years were calculated for the population <75 years old by sex for the following groups of cancer deaths: (1) avoidable through primary prevention; (2) avoidable through early detection and treatment; (3) avoidable through improved treatment and medical care; and (4) remaining cancer deaths. To assess time trends in ASMRs, estimated annual percentage changes (EAPCs) with 95% confidence intervals (95% CIs) were calculated. RESULTS:In Switzerland and neighbouring countries cancer mortality in persons <75 years old continuously decreased 1996-2010. Avoidable cancer mortality decreased in all groups of avoidable cancer deaths in both sexes, with one exception. ASMRs for causes avoidable through primary prevention increased in females in all countries (in Switzerland from 16.2 to 20.3 per 100 000 person years, EAPC 2.0 [95% CI 1.4 to 2.6]). Compared with its neighbouring countries, Switzerland showed the lowest rates for all groups of avoidable cancer mortality in males 2008-2010. CONCLUSION:Overall avoidable cancer mortality decreased, indicating achievements in cancer care and related health policies. However, increasing trends in avoidable cancer mortality through primary prevention for females suggest there is a need in Switzerland and its European neighbouring countries to improve primary prevention.
journal_name
Swiss Med Wklyjournal_title
Swiss medical weeklyauthors
Feller A,Mark MT,Steiner A,Clough-Gorr KMdoi
10.4414/smw.2015.14184subject
Has Abstractpub_date
2015-10-02 00:00:00pages
w14184eissn
1424-7860issn
1424-3997pii
smw-14184journal_volume
145pub_type
杂志文章abstract:QUESTIONS UNDER STUDY:Optimal oxygen saturation (SpO2) targets for extremely low gestational age neonates (ELGANs, gestational age [GA] <28 weeks) are unknown. Conflicting results from five recently published multicentre trials, which randomised ELGANs to high (91 to 95%) or low (85 to 89%) SpO2 targets from birth up t...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2015.14197
更新日期:2015-11-02 00:00:00
abstract::With regard to HCV elimination in opioid agonist therapy patients by 2030, case finding and regular screening for new and re-infections remain a challenge, especially for non-cohort patients in a decentralised setting. Documentation of the HCV sero- and RNA status of each opioid agonist therapy patient by the ca...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2020.20317
更新日期:2020-08-06 00:00:00
abstract::After the health catastrophe resulting from the widespread use of asbestos which was once hailed as a new miracle material, the increasing use of carbon nanotubes (CNTs) has spawned major concern due to their similarities in terms of size, shape and poor solubility. Assessment of genotoxicity has shown that CNTs can d...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:10.4414/smw.2012.13698
更新日期:2012-11-05 00:00:00
abstract:QUESTIONS UNDER STUDY / PRINCIPLES:Colonoscopies are complex procedures that depend greatly on the patient's cooperation and on the correct judgment of a tolerable amount of discomfort by the endoscopy team, even in sedated patients. Little is known regarding the accuracy of the patient comfort level assessments made b...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2012.13726
更新日期:2012-11-05 00:00:00
abstract:QUESTION UNDER STUDY:To assess clinical reactions, immune responses and adverse events to undiluted, three- and sixfold diluted Lister strain vaccine stockpiled in Switzerland. METHODS:A prospective, triple-blinded, randomised, parallel group clinical trial was performed. RESULTS:From 2001 to 2007 104 persons with an...
journal_title:Swiss medical weekly
pub_type: 杂志文章,随机对照试验
doi:2008/27/smw-11966
更新日期:2008-07-12 00:00:00
abstract::We report a case series of 11 patients with severe E. faecium infections treated with daptomycin. All strains were resistant to ampicillin (MIC >8 mg/l), but susceptible to vancomycin. Seven out of 11 strains were also highly resistant to gentamicin (MIC >500 mg/l). All patients were treated with multiple broad-spectr...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2012.13603
更新日期:2012-06-26 00:00:00
abstract:BACKGROUND:since 1999 data from pulmonary hypertension (PH) patients from all PH centres in Switzerland were prospectively collected. We analyse the epidemiological aspects of these data. METHODS:PH was defined as a mean pulmonary artery pressure of >25 mm Hg at rest or >30 mm Hg during exercise. Patients with pulmona...
journal_title:Swiss medical weekly
pub_type: 杂志文章,多中心研究
doi:2008/25/smw-11915
更新日期:2008-06-28 00:00:00
abstract:BACKGROUND:Renal replacement therapy for paediatric end-stage renal disease (ESRD) has developed steadily since its introduction five decades ago. Continuous and long-term analysis of patient outcomes is essential for quality control. METHODS:The Swiss Paediatric Renal Registry, founded in 1970, includes patients diag...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2020.20300
更新日期:2020-07-27 00:00:00
abstract:PRINCIPLES:Since the recommendation that infants sleep in the supine position, there has been an increase in cases of posterior positional plagiocephaly. Even though this condition is a purely cosmetic problem, if it is severe it may affect the child psychologically. Positioning may help in mild or moderate cases, but ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2007/25/smw-11702
更新日期:2007-06-30 00:00:00
abstract::Apart from the degree of stenosis, plaque morphology has emerged in recent years as an important contributory factor in stroke risk. Ultrasound studies have shown that hypo- or anechogenic plaques carry a higher risk of cerebrovascular events than echogenic ones. Similarly, heterogeneous plaques presenting a complex p...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2005/43/smw-11038
更新日期:2005-10-29 00:00:00
abstract:BACKGROUND:Preventive treatment may avoid future cases of tuberculosis among asylum seekers. The effectiveness of preventive treatment depends in large part on treatment completion. METHODS:In a prospective cohort study, asylum seekers of two of the Swiss Canton Vaud migration centres were screened with the Interferon...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2013.13860
更新日期:2013-09-06 00:00:00
abstract:QUESTIONS UNDER STUDY:Lung cancer belongs to the most common cancers in Switzerland. We examined trends in lung cancer incidence, with focus on sex, histology and laterality, in the Canton of Zurich since 1980. MATERIAL AND METHODS:Registry data consisting of 16 798 lung cancer cases from 1980 to 2010 were analysed. C...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2016.14327
更新日期:2016-07-11 00:00:00
abstract:QUESTIONS UNDER STUDY:The unexpected death of a preterm infant is an extremely painful situation for parents. Despite a number of quantitative studies, little is known about parents' inner experience. The aim of this study was to gather more in-depth information about what preoccupies parents in this situation of suffe...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2007/27/smw-11868
更新日期:2007-07-14 00:00:00
abstract::The current situation of the biomedical sciences is critically discussed. It can be summarized as follows: 1. We have to acknowledge the presence of a serious credibility problem, which might undermine the foundations of medical science. ("Sliding on a slippery slope") 2. Multiple forces going beyond simple conflicts ...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:10.4414/smw.2015.14120
更新日期:2015-03-13 00:00:00
abstract:PRINCIPLES:Apolipoprotein E (ApoE), an important glycoprotein in the transport, uptake and redistribution of cholesterol, is necessary in nerve tissue repair. The APOE gene (APOE) is involved in neurodegenerative diseases, the best-known association being that between the APOE ε4 allele and Alzheimer's disease. Multipl...
journal_title:Swiss medical weekly
pub_type: 杂志文章,多中心研究
doi:10.4414/smw.2010.13119
更新日期:2010-11-26 00:00:00
abstract::Our senses are the main information channels through which we perceive and interact with the world. Consequently, the physical and social functioning of patients suffering from severe sensory disabilities is limited on several levels. This has motivated the development of a novel therapeutic alternative: “artifi...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:10.4414/smw.2019.20061
更新日期:2019-06-02 00:00:00
abstract::Mantle cell lymphoma (MCL) is a relatively rare lymphoma entity accounting for an estimated 3%-6% of all non-Hodgkin's lymphoma cases. Characterised by both the incurability of indolent lymphomas and the rapid growth of aggressive lymphomas, MCL has a median overall survival of only 4-5 years. Although the disease oft...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:10.4414/smw.2013.13868
更新日期:2013-11-13 00:00:00
abstract:INTRODUCTION:It has been proposed that reactive oxygen species play a role in renal fibrosis. 8-OHdG, a metabolite of oxidative damage to leukocyte DNA, has been identified as a marker of oxidative stress in patients with chronic renal failure. MATERIALS AND METHODS:Seventy-four patients following nephrectomy were ret...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2011.13268
更新日期:2011-10-12 00:00:00
abstract:AIM:The levels of teamwork and clinician burnout in healthcare differ depending on demographic and unit characteristics. However, the impact of these characteristics varies between clinical settings. In addition, the impact of objectively measured workload in such settings is largely unknown. The aim of this study was ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2019.20033
更新日期:2019-03-24 00:00:00
abstract:OBJECTIVES:Several studies have reported prolonged QTc intervals in patients under methadone maintenance treatment, including development of torsade-de-pointes arrhythmia and death. It is still not clear why some patients develop critical QTc extensions while others do not. METHODS:ECG findings in a convenience sample...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2013.13852
更新日期:2013-09-06 00:00:00
abstract:QUESTIONS UNDER STUDY:Suicidal behaviour is a major source of burden of disease. While most studies focus on cost associated with completed suicides, data on costs of, non-lethal, suicide attempts are lacking. The aim of this study was to assess direct annual cost of suicide attempts in Basel in 2003 from a health serv...
journal_title:Swiss medical weekly
pub_type: 杂志文章,多中心研究
doi:10.4414/smw.2012.13648
更新日期:2012-07-23 00:00:00
abstract:OBJECTIVE:To evaluate the current prevalence of self-reported interpersonal violence amongst patients consulting at the emergency department (ED) of a university hospital and to describe the characteristics of the violence sustained. METHODS:Ours was a cross-sectional study using a modified version of the Partner Viol...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2019.20147
更新日期:2019-12-17 00:00:00
abstract:QUESTIONS UNDER STUDY:In the next Swiss National HIV and Sexually Transmitted Infection (STI) Strategy 2011-2017, STI control will be integrated with HIV prevention. Information is needed which will improve the targeting of professional education. The objective of this study was to describe the clinical specialities an...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2011.13143
更新日期:2011-01-20 00:00:00
abstract:BACKGROUND:A clinical research application must be submitted for approval by a competent ethics committee (EC) before a study can be executed. There is very limited information on how such submissions could be optimised, especially regarding research in children and adolescents, which requires particular caution and ag...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2020.20267
更新日期:2020-06-19 00:00:00
abstract:QUESTIONS UNDER STUDY:Postmenopausal women are more likely to develop coronary artery disease than premenopausal women of the same age. Postmenopausal oral oestrogen therapy is associated with increased levels of high-density lipoprotein (HDL) cholesterol and decreased levels of lowdensity lipoprotein (LDL) cholesterol...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2006/31/smw-11390
更新日期:2006-08-05 00:00:00
abstract:BACKGROUND:Low-molecular-weight heparins (LMWH) have been shown to be safer, more effective and more convenient than unfractionated heparin (UFH) in many clinical situations. However, their use is limited in patients with renal insufficiency (RI) due to bioaccumulation. METHOD:The literature is critically reviewed and...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:smw-11284
更新日期:2009-08-08 00:00:00
abstract:BACKGROUND:Neuroendocrine neoplasms (NENs) are difficult to diagnose. We used SwissNET data to characterise NEN patients followed in the two academic centres of western Switzerland (WS), and to compare them with patients followed in eastern Switzerland (ES) as well as with international guidelines. METHOD:SwissNET is ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2014.13924
更新日期:2014-02-19 00:00:00
abstract:BACKGROUND:B-type natriuretic peptide (BNP) has been proven to be a biochemical marker of severity of congestive heart failure. We are aware of only few papers reporting the association of BNP elevation and pulmonary hypertension (primary, thromboembolic, or as a consequence of chronic obstructive pulmonary disease). L...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2003/37/smw-10367
更新日期:2003-09-26 00:00:00
abstract::Dementia with Lewy bodies (DLB) accounts for 15-20% of all autopsy confirmed dementias in old age. Characteristic histopathological changes are intracellular Lewy bodies and Lewy neurites, with abundant senile plaques but sparse neurofibrillary tangles. Core clinical features are fluctuating cognitive impairment, pers...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:2003/09/smw-10028
更新日期:2003-03-08 00:00:00
abstract:AIM OF THE STUDY:In Switzerland, screening concepts for the prevention of sports-associated sudden cardiac death are still insufficiently established in the large group of competitive athletes who are not integrated in an Olympic- or other high-level squad. The aim of the present study was to objectively determine the ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2012.13575
更新日期:2012-05-31 00:00:00