Daptomycin for highly resistant Enterococcus faecium infection.

Abstract:

:We report a case series of 11 patients with severe E. faecium infections treated with daptomycin. All strains were resistant to ampicillin (MIC >8 mg/l), but susceptible to vancomycin. Seven out of 11 strains were also highly resistant to gentamicin (MIC >500 mg/l). All patients were treated with multiple broad-spectrum antibiotics prior to isolation of E. faecium and had severe underlying diseases. Our experience suggests that salvage therapy with daptomycin might be a safe and efficacious treatment for E. faecium infections.

journal_name

Swiss Med Wkly

journal_title

Swiss medical weekly

authors

Rosin C,Bernsmeier C,Entenza JM,Moreillon P,Frei R,Weisser M,Flückiger U

doi

10.4414/smw.2012.13603

subject

Has Abstract

pub_date

2012-06-26 00:00:00

pages

w13603

eissn

1424-7860

issn

1424-3997

pii

smw-13603

journal_volume

142

pub_type

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