Renal denervation: time to open Pandora's box.

abstract：:Mantle cell lymphoma (MCL) is a relatively rare lymphoma entity accounting for an estimated 3%-6% of all non-Hodgkin's lymphoma cases. Characterised by both the incurability of indolent lymphomas and the rapid growth of aggressive lymphomas, MCL has a median overall survival of only 4-5 years. Although the disease oft...

journal_title：Swiss medical weekly

authors： Hitz F,Bargetzi M,Cogliatti S,Lohri A,Taverna C,Renner C,Mey U

更新日期：2013-11-13 00:00:00

abstract：BACKGROUND:Low-molecular-weight heparins (LMWH) have been shown to be safer, more effective and more convenient than unfractionated heparin (UFH) in many clinical situations. However, their use is limited in patients with renal insufficiency (RI) due to bioaccumulation. METHOD:The literature is critically reviewed and...

journal_title：Swiss medical weekly

authors： Schmid P,Fischer AG,Wuillemin WA

更新日期：2009-08-08 00:00:00

abstract：OBJECTIVES:To compare the long-term effects of comprehensive outpatient versus inpatient rehabilitation with respect to morbidity and mortality, as well as to changes in physical performance and physical activity. DESIGN:A total of 163 consecutive patients were enrolled for comprehensive cardiac rehabilitation (CCR) f...

journal_title：Swiss medical weekly

authors： Steinacker JM,Liu Y,Muche R,Koenig W,Hahmann H,Imhof A,Kropf C,Brandstetter S,Schweikert B,Leidl R,Schiefer DH

更新日期：2011-01-06 00:00:00

abstract：BACKGROUND:Thyroid hemiagenesis (TH) is a rare congenital abnormality of the thyroid gland, characterised by the absence of one lobe. The true prevalence of this congenital abnormality is not known because the absence of one thyroid lobe usually does not cause clinical symptoms by itself. This study aims to identify th...

journal_title：Swiss medical weekly

authors： Berker D,Ozuguz U,Isik S,Aydin Y,Ates Tutuncu Y,Akbaba G,Guler S

更新日期：2010-02-20 00:00:00

abstract：:Multicentric carpotarsal osteolysis (MCTO) is an autosomal dominant disease of the skeleton characterised by progressive destruction of carpal and tarsal bones. Recently, it has been demonstrated that this disease is caused by heterozygous mutations in the gene for the transcriptional repressor MAFB. We analysed genom...

journal_title：Swiss medical weekly

authors： Zhuang L,Adler S,Aeberli D,Villiger PM,Trueb B

更新日期：2017-10-27 00:00:00

abstract：BACKGROUND:The European Consensus Statement of Neonatal Hearing recommended universal newborn hearing screening (UNHS) in 1998. UNHS was introduced in Switzerland in 1999 under the auspices of a "Swiss Working Group Hearing Screening in Newborns". The aim of this study was to evaluate the number of newborns being scree...

journal_title：Swiss medical weekly

authors： Metzger D,Pezier TF,Veraguth D

更新日期：2013-12-13 00:00:00

abstract：:The antineutrophil cytoplasmic antibody (ANCA) associated vasculitides (AAV) are a group of primary vasculitides that affect predominantly small- to medium-sized blood vessels. AAV include granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA) and eosinophilic granulomatosis with polyangiitis (EGPA). D...

journal_title：Swiss medical weekly

authors： Daikeler T,Kistler AD,Martin PY,Vogt B,Huynh-Do U

更新日期：2015-02-06 00:00:00

abstract：OBJECTIVES:First, to test whether current injury is more closely related to acute intake than to usual consumption patterns, and second, to test whether repeated injury is more closely related to general consumption patterns than to acute intake. METHODS:Screening of alcohol consumption of 7,872 patients enrolling bet...

journal_title：Swiss medical weekly

authors： Gmel G,Givel JC,Yersin B,Daeppen JB

更新日期：2007-11-17 00:00:00

abstract：STUDY/PRINCIPLES:Physical activity improves the clinical course of the metabolic syndrome and its risk factors. The aim of this study was to investigate the physical activity behaviour in patients with metabolic syndrome in regard to the recommendation of the Federal Offices of Public Health (BAG) and Sports (BASPO): "...

journal_title：Swiss medical weekly

authors： Murer M,Schmied C,Battegay E,Keller DI

更新日期：2012-10-25 00:00:00

abstract：BACKGROUND:Adverse reactions to nonsteroidal antiinflammatory drugs (NSAIDs) are frequently reported, particularly among asthmatic patients. To date, there is no causal treatment available apart from tolerance induction. Therefore, the search for safe alternative drugs is of pivotal importance in clinical practice. OB...

journal_title：Swiss medical weekly

authors： Roll A,Wüthrich B,Schmid-Grendelmeier P,Hofbauer G,Ballmer-Weber BK

更新日期：2006-10-28 00:00:00

abstract：QUESTIONS UNDER STUDY:Paraoxonase-1 (PON1) is an HDL-bound enzyme system which plays a key role in the protection of LDL and HDL from oxidation by hydrolysing activated phospholipids and lipid peroxide products. Oxidative stress has been involved in the pathogenesis of many complications of human pregnancy, including e...

journal_title：Swiss medical weekly

authors： Toy H,Camuzcuoglu H,Celik H,Erel O,Aksoy N

更新日期：2009-02-07 00:00:00

abstract：:Hepatitis C virus (HCV) infection is a leading cause of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma worldwide. While current therapeutic options for hepatitis C are limited, recent progress in the understanding of the biology of HCV led to the identification of novel targets for antiviral interven...

journal_title：Swiss medical weekly

authors： Moradpour D,Cerny A,Heim MH,Blum HE

更新日期：2001-06-02 00:00:00

abstract：:The anti-inflammatory genes, haem oxygenase 1 (HO-1, HMOX1) rs2071746 (unrestricted model: p = 9.07 × 10-4; recessive model: p = 4.99 × 10-4; multiplicative model: p = 0.0009; and additive model: p = 1.87 × 10-4) and interleukin-10 (IL-10) rs1800872 (dominant model: p = 0.0277) have been associated with paediatric inf...

journal_title：Swiss medical weekly

authors： Lin Z,Hao H,Hegarty JP,Lin TR,Wang Y,Harris LR,Xu HN,Wu R,Thomas NJ,Floros J

更新日期：2017-08-02 00:00:00

abstract：:Coronary microcirculation plays a crucial role for the outcomes of patients with STEMI. Although PPCI improves outcomes compared to thrombolysis, a substantial amount of STEMI patients do not achieve optimal myocardial reperfusion. Angiographic methods for assessment of reperfusion like TIMI Flow and MBG are easy to u...

journal_title：Swiss medical weekly

authors： Cuculi F,De Caterina AR,Kharbanda RK,Banning AP

更新日期：2011-12-09 00:00:00

abstract：:A nationwide survey was conducted in Switzerland to assess the quality level of osteoporosis management in patients aged 50 years or older presenting with a fragility fracture to the emergency ward of the participating hospitals. Eight centres recruited 4966 consecutive patients who presented with one or more fracture...

journal_title：Swiss medical weekly

authors： Suhm N,Lamy O,Lippuner K,OsteoCare study group.

更新日期：2008-11-15 00:00:00

abstract：BACKGROUND:Based on a reduction in morbidity and mortality, cardiac resynchronisation therapy (CRT) has evolved as a standard therapy for patients with advanced heart failure. OBJECTIVE:To provide insight into patient demographics, safety, echocardiographic remodelling and long-term follow-up of patients treated with ...

journal_title：Swiss medical weekly

authors： Winnik S,Elsener C,Seifert B,Starck C,Straub A,Saguner AM,Breitenstein A,Krasniqi N,Wilhelm MJ,Haegeli L,Duru F,Benussi S,Maisano F,Lüscher TF,Holzmeister J,Huerlimann D,Ruschitzka F,Steffel J

更新日期：2017-04-18 00:00:00

abstract：OBJECTIVES:To assess adherence to recommended standards of diabetes care by Swiss primary care physicians. METHODS:Medical files of community-based primary care physician were reviewed to assess adherence to recommended standards of diabetes care. These standards of care were based on a uniform set of definitions addr...

journal_title：Swiss medical weekly

authors： Bovier PA,Sebo P,Abetel G,George F,Stalder H

更新日期：2007-03-24 00:00:00

abstract：QUESTION UNDER STUDY:What are the trends in avoidable cancer mortality in Switzerland and neighbouring countries? METHODS:Mortality data and population estimates 1996-2010 were obtained from the Swiss Federal Statistical Office for Switzerland and the World Health Organization Mortality Database (http://www.who.int/he...

journal_title：Swiss medical weekly

authors： Feller A,Mark MT,Steiner A,Clough-Gorr KM

更新日期：2015-10-02 00:00:00

abstract：PRINCIPLES:Heart failure is associated with a grim prognosis. Disease management programmes can improve prognosis in heart failure patients but the applicability to the general population remains limited. We aimed to compare the outcome, pharmacological therapy, and quality of life in unselected heart failure patients ...

journal_title：Swiss medical weekly

authors： Lainscak M,Keber I

更新日期：2006-04-29 00:00:00

abstract：:This article discusses communication challenges in end-of-life decision making and outlines strategies from an area of growing interest and research. ...

journal_title：Swiss medical weekly

authors： Becker C,Beck K,Vincent A,Hunziker S

更新日期：2020-09-18 00:00:00

abstract：BACKGROUND:Organs donated for transplantation remain a scarce resource in Switzerland. One of the reasons for this situation is the high percentage of patients or families who refuse to consent to donation. This study aimed to provide an overview of attitudes towards organ donation among Swiss residents, including any ...

journal_title：Swiss medical weekly

authors： Weiss J,Shaw D,Schober R,Abati V,Immer FF,Comité National du Don d'Organes Cndo

更新日期：2017-02-03 00:00:00

abstract：AIMS OF THE STUDY:Premature discontinuation occurs in about 25% of randomised clinical trials in Switzerland; it mainly affects investigator-initiated trials and is mostly due to problems with recruitment of patients. The aim of this study was to qualitatively investigate reasons for trial discontinuation due to poor p...

journal_title：Swiss medical weekly

authors： Briel M,Elger B,von Elm E,Satalkar P

更新日期：2017-11-16 00:00:00

abstract：:Minimal residual disease (MRD) refers to the small number of malignant cells that remain after therapy when the patient is in remission and shows no symptoms or overt signs of disease. Current treatment protocols for haematological malignancies allow most patients to obtain some form of MRD state, but cure seldom foll...

journal_title：Swiss medical weekly

authors： Hauwel M,Matthes T

更新日期：2014-01-22 00:00:00

abstract：:Our senses are the main information channels through which we perceive and interact with the world. Consequently, the physical and social functioning of patients suffering from severe sensory disabilities is limited on several levels. This has motivated the development of a novel therapeutic alternative: “artifi...

journal_title：Swiss medical weekly

authors： Pérez Fornos A,Van de Berg R,Sommerhalder J,Guinand N

更新日期：2019-06-02 00:00:00

abstract：AIMS OF THE STUDY:To describe patterns of systemic lupus erythematosus (SLE) care and the clinical effectiveness of belimumab plus standard of care therapy in a real-world clinical setting in Switzerland. METHODS:This multicentre, observational, retrospective cohort study included adults with SLE who initiated belimum...

journal_title：Swiss medical weekly

authors： von Kempis J,Duetsch S,Reuschling N,Villiger R,Villiger PM,Vallelian F,Schaer DJ,Mueller RB

更新日期：2019-03-10 00:00:00

abstract：:The atherogenic lipoprotein phenotype is characterised by a moderate increase in plasma triglycerides, a decrease in high density lipoprotein cholesterol and the prevalence of smaller denser low density lipoprotein particles. The prevalence of this partially inheritable phenotype is approximately 30% and is a feature ...

journal_title：Swiss medical weekly

authors： Berneis K,Rizzo M

更新日期：2004-12-18 00:00:00

abstract：QUESTIONS UNDER STUDY:In the next Swiss National HIV and Sexually Transmitted Infection (STI) Strategy 2011-2017, STI control will be integrated with HIV prevention. Information is needed which will improve the targeting of professional education. The objective of this study was to describe the clinical specialities an...

journal_title：Swiss medical weekly

authors： Baillif A,Low N

更新日期：2011-01-20 00:00:00

abstract：:The WHO recommends screening of Latin American migrants for Chagas disease to reduce morbidity and mortality and increase the likelihood of eradicating the disease. The objective was to assess the feasibility and acceptability of a screening strategy in one Swiss canton. From February 2011 to September 2012, people at...

journal_title：Swiss medical weekly

authors： Da Costa-Demaurex C,Cárdenas MT,Aparicio H,Bodenmann P,Genton B,D'Acremont V

更新日期：2019-04-04 00:00:00

abstract：:Sequencing the human genome was the big challenge of the last decade. Ten years later, the large amount of DNA sequences accumulated in our databases allows us to look at genome variations between humans. The level of complexity of these variations is much higher than previously expected. It goes from changes in the n...

journal_title：Swiss medical weekly

authors： Paoloni-Giacobino A

更新日期：2011-12-19 00:00:00

abstract：:Of the two million people estimated to be newly infected with human immunodeficiency virus (HIV) every year, 95% live in poorer regions of the world where effective HIV treatment is not universally available. Strategies to reduce the spread of HIV infection, which predominantly occurs via sexual contact, are urgently ...

journal_title：Swiss medical weekly

authors： Hartley O,Martins E,Scurci I

更新日期：2018-01-26 00:00:00