Management of fragility fractures in Switzerland: results of a nationwide survey.

Abstract:

:A nationwide survey was conducted in Switzerland to assess the quality level of osteoporosis management in patients aged 50 years or older presenting with a fragility fracture to the emergency ward of the participating hospitals. Eight centres recruited 4966 consecutive patients who presented with one or more fractures between 2004 and 2006. Of these, 3667 (2797 women, 73.8 years old and 870 men, 73.0 years old in average) were considered as having a fragility fracture and included in the survey. Included patients presented with a fracture of the upper limbs (30.7%), lower limbs (26.4%), axial skeleton (19.5%) or another localisation, including malleolar fractures (23.4%). Thirty-two percent reported one or more previous fractures during adulthood. Of the 2941 (80.2%) hospitalised women and men, only half returned home after discharge. During diagnostic workup, dual x-ray absorptiometry (DXA) measurement was performed in 31.4% of the patients only. Of those 46.0% had a T-score < or =-2.5 SD and 81.1% < or =-1.0 SD. Osteoporosis treatment rate increased from 26.3% before fracture to 46.9% after fracture in women and from 13.0% to 30.3% in men. However, only 24.0% of the women and 13.8% of the men were finally adequately treated with a bone active substance, generally an oral bisphosphonate, with or without calcium / vitamin D supplements. A positive history of previous fracture vs none increased the likelihood of getting treatment with a bone active substance (36.6 vs 17.9%, ? 18.7%, 95% CI 15.1 to 22.3, and 22.6 vs 9.9%, ? 12.7%, CI 7.3 to 18.5, in women and men, respectively). In Switzerland, osteoporosis remains underdiagnosed and undertreated in patients aged 50 years and older presenting with a fragility fracture.

journal_name

Swiss Med Wkly

journal_title

Swiss medical weekly

authors

Suhm N,Lamy O,Lippuner K,OsteoCare study group.

doi

/aop/smw-aop12294

subject

Has Abstract

pub_date

2008-11-15 00:00:00

pages

674-83

issue

45-46

eissn

1424-7860

issn

1424-3997

pii

smw-aop12294

journal_volume

138

pub_type

杂志文章
  • Atypical antipsychotics in the treatment of schizophrenia.

    abstract::Over the last few years atypical antipsychotics have been used increasingly in the pharmacological treatment of schizophrenia. This review provides an overview of the pharmacological and clinical characteristics of atypical antipsychotics. In particular we discuss their efficacy in treating psychotic and negative symp...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:2003/05/smw-10003

    authors: Bridler R,Umbricht D

    更新日期:2003-02-08 00:00:00

  • Elevation of B-type natriuretic peptide levels in acute respiratory distress syndrome.

    abstract:BACKGROUND:B-type natriuretic peptide (BNP) has been proven to be a biochemical marker of severity of congestive heart failure. We are aware of only few papers reporting the association of BNP elevation and pulmonary hypertension (primary, thromboembolic, or as a consequence of chronic obstructive pulmonary disease). L...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:2003/37/smw-10367

    authors: Maeder M,Ammann P,Rickli H,Diethelm M

    更新日期:2003-09-26 00:00:00

  • LDL size: does it matter?

    abstract::The atherogenic lipoprotein phenotype is characterised by a moderate increase in plasma triglycerides, a decrease in high density lipoprotein cholesterol and the prevalence of smaller denser low density lipoprotein particles. The prevalence of this partially inheritable phenotype is approximately 30% and is a feature ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:2004/49/smw-10813

    authors: Berneis K,Rizzo M

    更新日期:2004-12-18 00:00:00

  • Diagnosis and workup of 522 consecutive patients with neuroendocrine neoplasms in Switzerland.

    abstract:BACKGROUND:Neuroendocrine neoplasms (NENs) are difficult to diagnose. We used SwissNET data to characterise NEN patients followed in the two academic centres of western Switzerland (WS), and to compare them with patients followed in eastern Switzerland (ES) as well as with international guidelines. METHOD:SwissNET is ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2014.13924

    authors: Gouffon M,Iff S,Ziegler K,Larche M,Schwarzenbach C,Prior JO,Matter M,Stettler C,Pralong FP

    更新日期:2014-02-19 00:00:00

  • Liveborn and stillborn very low birthweight infants in Switzerland: comparison between hospital based birth registers and the national birth register.

    abstract:BACKGROUND AND AIM:Perinatal and infant mortality rates are considered key indicators of medical care. The aim of this investigation was to examine how representative and reliable the official national figures of Switzerland are by comparing them with the data in local birth registers. METHODS:124 of 156 maternity hos...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:2005/29/smw-10946

    authors: Müller M,Drack G,Schindler C,Bucher HU

    更新日期:2005-07-23 00:00:00

  • Transition to postgraduate practice: perceptions of preparedness and experience of the daily work of junior residents.

    abstract:BACKGROUND:The transition from undergraduate to postgraduate training is a crucial career step for physicians. Several international studies have shown that graduates feel insufficiently prepared to perform various aspects of clinical practice. The publication of a national framework for undergraduate medical education...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2020.20370

    authors: Monti M,Brunet L,Michaud PA

    更新日期:2020-11-24 00:00:00

  • An evaluation of patient satisfaction amongst family practice patients with diverse ethnic backgrounds.

    abstract:OBJECTIVE:The aim of this study was to examine the impact of patients' ethnic diversity on the patient satisfaction rates. DESIGN:We used the methodology developed in an international EUROPE study. The patients were asked to fill in self-administered questionnaires on their evaluations of the care received in the year...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:2002/09/smw-09800

    authors: Kersnik J,Ropret T

    更新日期:2002-03-09 00:00:00

  • Diffuse large B-cell lymphoma chemotherapy reveals a combined immunodeficiency syndrome in cartilage hair hypoplasia.

    abstract::Cartilage hair hypoplasia (CHH) is a rare autosomal recessive ribosomopathy characterised by skeletal and integumentary system manifestations. It may also present with varied forms and intensities of haematopoietic and/or immune disorders. We report a 27-year-old female who presented a picture of combined immunodefici...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2018.14606

    authors: Nguyen A,Martin Silva N,de Boysson H,Damaj G,Aouba A

    更新日期:2018-04-24 00:00:00

  • Impact of body temperature on in-hospital and long-term mortality in patients with acute heart failure.

    abstract:OBJECTIVES:Body temperature (BT) was shown to have impact on outcome in several medical conditions. This study investigated the prognostic impact of BT in patients with acute heart failure (HF). DESIGN AND PATIENTS:The B-type natriuretic peptide for Acute Shortness of breath EvaLuation (BASEL) study prospectively enro...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:2008/21/smw-12013

    authors: Klima T,Schindler C,Christ M,Rosser A,Breidthardt T,Hochholzer W,Laule K,Mueller C

    更新日期:2008-05-31 00:00:00

  • No association between herpes simplex virus 1 and cardiac myxoma.

    abstract:PRINCIPLES:Cardiac myxoma is the most commonly diagnosed cardiac tumour. Infection of herpes simplex virus 1 (HSV1) has been postulated to be a factor for this pathologic entity. The aim of the current study was to evaluate the association between HSV 1 and myxoma occurrence. METHODS:Between 1965 and 2005, 70 patients...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2011.13223

    authors: Schurr UP,Berdajs DA,Bode B,Dzemali O,Emmert MY,Genoni M

    更新日期:2011-08-26 00:00:00

  • Oscillometric measurement of ankle-brachial index in patients with suspected peripheral disease: comparison with Doppler method.

    abstract:QUESTION UNDER STUDY:Purpose was to validate accuracy and reliability of automated oscillometric ankle-brachial (ABI) measurement prospectively against the current gold standard of Doppler-assisted ABI determination. METHODS:Oscillometric ABI was measured in 50 consecutive patients with peripheral arterial disease (n ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:smw-12636

    authors: Diehm N,Dick F,Czuprin C,Lawall H,Baumgartner I,Diehm C

    更新日期:2009-06-27 00:00:00

  • Insulin sensitivity in type 2 diabetes is closely associated with LDL particle size.

    abstract:PRINCIPLES:Small dense LDLs have been found to be associated with type 2 diabetes (T2DM). This association has been observed in the context of decreased HDL cholesterol and increased triglycerides. METHODS:In the present study the relationship between LDL particle size and insulin sensitivity was assessed in 46 patien...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:2008/19/smw-12124

    authors: Krayenbuehl PA,Wiesli P,Schmid C,Lehmann R,Spinas GA,Berneis K

    更新日期:2008-05-03 00:00:00

  • The role of teriparatide in sequential and combination therapy of osteoporosis.

    abstract::Osteoporosis is complicated by the occurrence of fragility fractures. Over past years, various treatment options have become available, mostly potent antiresorptive agents such as bisphosphonates and denosumab. However, antiresorptive therapy cannot fully and rapidly restore bone mass and structure that has been lost ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:10.4414/smw.2014.13952

    authors: Meier C,Lamy O,Krieg MA,Mellinghoff HU,Felder M,Ferrari S,Rizzoli R

    更新日期:2014-06-04 00:00:00

  • Tolerance to celecoxib in patients with a history of adverse reactions to nonsteroidal anti-inflammatory drugs.

    abstract:BACKGROUND:Adverse reactions to nonsteroidal antiinflammatory drugs (NSAIDs) are frequently reported, particularly among asthmatic patients. To date, there is no causal treatment available apart from tolerance induction. Therefore, the search for safe alternative drugs is of pivotal importance in clinical practice. OB...

    journal_title:Swiss medical weekly

    pub_type: 临床试验,杂志文章

    doi:2006/43/smw-11358

    authors: Roll A,Wüthrich B,Schmid-Grendelmeier P,Hofbauer G,Ballmer-Weber BK

    更新日期:2006-10-28 00:00:00

  • High rate of completion of preventive therapy for latent tuberculosis infection among asylum seekers in a Swiss Canton.

    abstract:BACKGROUND:Preventive treatment may avoid future cases of tuberculosis among asylum seekers. The effectiveness of preventive treatment depends in large part on treatment completion. METHODS:In a prospective cohort study, asylum seekers of two of the Swiss Canton Vaud migration centres were screened with the Interferon...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2013.13860

    authors: Sarivalasis A,Bodenmann P,Langenskiold E,Lutchmaya-Flick C,Daher O,Zellweger JP

    更新日期:2013-09-06 00:00:00

  • Patients' understanding of blood tests and attitudes to HIV screening in the emergency department of a Swiss teaching hospital: a cross-sectional observational study.

    abstract:BACKGROUND:In Switzerland, patients may undergo "blood tests" without being informed what these are screening for. Inadequate doctor-patient communication may result in patient misunderstanding. We examined what patients in the emergency department (ED) believed they had been screened for and explored their attitudes t...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2015.14206

    authors: Favre-Bulle T,Baudat D,Darling KE,Mamin R,Peters S,Cavassini M,Hugli O

    更新日期:2015-12-04 00:00:00

  • Arrhythmias in patients with surgically treated atrial septal defects.

    abstract::Atrial arrhythmias complicate the clinical course of adult patients with an atrial septal defect. Atrial flutter is more prevalent in younger patients, and frequently regresses after surgical defect closure. Atrial fibrillation however, which results from a chronic underlying disease, rarely reverts to sinus rhythm af...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:2005/11/smw-10926

    authors: Berger F,Vogel M,Kretschmar O,Dave H,Prêtre R,Dodge-Khatami A

    更新日期:2005-03-19 00:00:00

  • Treatment intensification with insulin glargine in patients with inadequately controlled type 2 diabetes improves glycaemic control with a high treatment satisfaction and no weight gain.

    abstract:PRINCIPLES:We aimed to evaluate the efficacy of, and treatment satisfaction with, insulin glargine administered with SoloSTAR® or ClikSTAR® pens in patients with type 2 diabetes mellitus managed by primary care physicians in Switzerland. METHODS:A total of 327 patients with inadequately controlled type 2 diabetes were...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2015.14114

    authors: Riebenfeld D,Spirk D,Mathis A,Villiger L,Gerber PA,Gasser UE,Lehmann R

    更新日期:2015-03-05 00:00:00

  • Management of hepatitis C in opioid agonist therapy patients of the Swiss canton Aargau within and outside the cohort study.

    abstract::With regard to HCV elimination in opioid agonist therapy patients by 2030, case finding and regular screening for new and re-infections remain a challenge, especially for non-cohort patients in a decentralised setting. Documentation of the HCV sero- and RNA status of each opioid agonist therapy  patient by the ca...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2020.20317

    authors: Schürch S,Fux CA,Dehler S,Conen A,Knuchel J,Friedl A,Eigenmann F,Roser P,Ackle P,Bregenzer A

    更新日期:2020-08-06 00:00:00

  • Medical care of type 2 diabetes mellitus in light of international and national recommendations: a retrospective analysis.

    abstract:QUESTION UNDER STUDY:Type 2 diabetes mellitus (T2Dm) is a chronic disease with great economic impact. In 2009, the Swiss Society for Endocrinology and Diabetes (SSED) published recommendations for treatment of T2Dm. In Switzerland, few data are currently available on metabolic control and physician compliance with trea...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2013.13871

    authors: Burgmann K,Fatio S,Jordi B,Rutishauser J

    更新日期:2013-10-25 00:00:00

  • Astonishing advances in mouse genetic tools for biomedical research.

    abstract::The humble house mouse has long been a workhorse model system in biomedical research. The technology for introducing site-specific genome modifications led to Nobel Prizes for its pioneers and opened a new era of mouse genetics. However, this technology was very time-consuming and technically demanding. As a result, m...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:10.4414/smw.2015.14186

    authors: Kaczmarczyk L,Jackson WS

    更新日期:2015-10-29 00:00:00

  • Social, cultural and experiential patterning of attitudes and behaviour towards assisted suicide in Switzerland: evidence from a national population-based study.

    abstract::Switzerland has the longest history of the legal practice of non-physician assisted suicide of any country. Assisted suicide is not very tightly regulated in Switzerland, and almost all assisted suicides are supported by a right-to-die organisation. Our study investigates older adults’ attitudes and behaviour to...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2020.20275

    authors: Vilpert S,Bolliger E,Borrat-Besson C,Borasio GD,Maurer J

    更新日期:2020-07-01 00:00:00

  • Treatment of immune thrombocytopenia with intravenous immunoglobulin and insights for other diseases. A historical review.

    abstract::Since 1946 the development of fractionation and purification methods of human plasma led to biologic immunoglobulin for intravenous use (IVIG). In 1980 a child with refractory immune thrombocytopenia (ITP), bleeding and secondary hypogammaglobulinaemia due to long term immunosuppressive treatment got IVIG. His platele...

    journal_title:Swiss medical weekly

    pub_type: 历史文章,杂志文章,评审

    doi:10.4414/smw.2012.13593

    authors: Imbach P

    更新日期:2012-05-31 00:00:00

  • The predictive validity of the aptitude test for the performance of students starting a medical curriculum.

    abstract:INTRODUCTION:Selection of medical students varies between German- and French-speaking Swiss faculties. Geneva introduced an aptitude test in 2010, aimed at helping decision making among students. The test was compulsory: it had to be taken by those who intended to register for medical studies. But it was not selective:...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2013.13872

    authors: Cerutti B,Bernheim L,van Gessel E

    更新日期:2013-09-19 00:00:00

  • Clinical settings and specialties notifying cases of bacterial sexually transmitted infections in Switzerland: cross-sectional study.

    abstract:QUESTIONS UNDER STUDY:In the next Swiss National HIV and Sexually Transmitted Infection (STI) Strategy 2011-2017, STI control will be integrated with HIV prevention. Information is needed which will improve the targeting of professional education. The objective of this study was to describe the clinical specialities an...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2011.13143

    authors: Baillif A,Low N

    更新日期:2011-01-20 00:00:00

  • Confusion between valGANciclovir (Valcyte®) and vALAcyclovir (Valtrex®).

    abstract::No abstract available (Letter to the editor). ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2012.13639

    authors:

    更新日期:2012-07-17 00:00:00

  • Epidemiology and pathophysiology of obesity as cause of cancer.

    abstract::According to World Health Organisation estimates 1.1 billion people were overweight or obese worldwide in the year 2000 with the prevalence rapidly increasing. Compelling evidence suggests that excess body weight is a risk factor for several cancer types including cancer of the colon, breast, endometrium, kidney, oeso...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:2007/03/smw-11435

    authors: Ceschi M,Gutzwiller F,Moch H,Eichholzer M,Probst-Hensch NM

    更新日期:2007-01-27 00:00:00

  • Bosentan therapy for chronic thromboembolic pulmonary hypertension. A national open label study assessing the effect of Bosentan on haemodynamics, exercise capacity, quality of life, safety and tolerability in patients with chronic thromboembolic pulmonar

    abstract:STUDY OBJECTIVES:we performed an open-label national study to evaluate the effects of Bosentan on haemodynamics, exercise capacity, quality of life, safety and tolerability in patients with chronic thromboembolic pulmonary hypertension (CTEPH). PATIENTS AND METHODS:fifteen patients with CTEPH not eligible or waiting f...

    journal_title:Swiss medical weekly

    pub_type: 临床试验,杂志文章

    doi:2007/41/smw-11819

    authors: Ulrich S,Speich R,Domenighetti G,Geiser T,Aubert JD,Rochat T,Huber L,Treder U,Fischler M

    更新日期:2007-10-20 00:00:00

  • Diagnosis and treatment of mantle cell lymphoma.

    abstract::Mantle cell lymphoma (MCL) is a relatively rare lymphoma entity accounting for an estimated 3%-6% of all non-Hodgkin's lymphoma cases. Characterised by both the incurability of indolent lymphomas and the rapid growth of aggressive lymphomas, MCL has a median overall survival of only 4-5 years. Although the disease oft...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:10.4414/smw.2013.13868

    authors: Hitz F,Bargetzi M,Cogliatti S,Lohri A,Taverna C,Renner C,Mey U

    更新日期:2013-11-13 00:00:00

  • Termination of pregnancy in a border region between Switzerland and Italy (2008-2015).

    abstract::In Switzerland, voluntary termination of pregnancy (VTP) can be performed in all public and private hospitals with an obstetrics/gynaecology department. For various reasons, many Italian women use the Swiss healthcare system, in particular in Canton Ticino, a border region adjacent to Italy in the southern part of Swi...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2018.14636

    authors: Reinholz D,Casati S,Beretta O,Merlani G

    更新日期:2018-07-09 00:00:00