A randomised prospective study to evaluate a rapid HIV-antibody assay in the management of cases of percutaneous exposure amongst health care workers.

abstract：:Pulmonary embolism (PE) is traditionally treated in hospital. Growing evidence from non randomized prospective studies suggests that a substantial proportion of patients with non-massive PE might be safely treated in the outpatient setting using low molecular weight heparins. Based on this evidence, professional socie...

journal_title：Swiss medical weekly

authors： Aujesky D,Mazzolai L,Hugli O,Perrier A

更新日期：2009-11-28 00:00:00

abstract：:The differential diagnosis for children with diabetes includes a group of monogenic diabetic disorders known as maturity-onset diabetes of the young (MODY). So far, six underlying gene defects have been identified. The most common subtypes are caused by mutations in the genes encoding the transcription factor HNF-1a (...

journal_title：Swiss medical weekly

authors： Schnyder S,Mullis PE,Ellard S,Hattersley AT,Flück CE

更新日期：2005-06-11 00:00:00

abstract：:The United Nations General Assembly has convened a Summit on non-communicable diseases (NCDs), an historic moment in the global combat of these disorders. Lifestyles in increasingly urban and globalised environments have led to a steep surge in NCD incidence in low and middle income countries, where two thirds of all ...

journal_title：Swiss medical weekly

authors： Probst-Hensch N,Tanner M,Kessler C,Burri C,Künzli N

更新日期：2011-09-07 00:00:00

abstract：PRINCIPLES:Current evidence indicates that chronic kidney disease (CKD) can be detected by simple laboratory tests. This study aimed to evaluate the cost-effectiveness of microalbuminuria screening and subsequent treatment in different populations. METHODS:Cost-effectiveness of microalbuminuria screening in a cohort o...

journal_title：Swiss medical weekly

authors： Kessler R,Keusch G,Szucs TD,Wittenborn JS,Hoerger TJ,Brügger U,Wieser S

更新日期：2012-02-03 00:00:00

abstract：:Of the two million people estimated to be newly infected with human immunodeficiency virus (HIV) every year, 95% live in poorer regions of the world where effective HIV treatment is not universally available. Strategies to reduce the spread of HIV infection, which predominantly occurs via sexual contact, are urgently ...

journal_title：Swiss medical weekly

authors： Hartley O,Martins E,Scurci I

更新日期：2018-01-26 00:00:00

abstract：:The atherogenic lipoprotein phenotype is characterised by a moderate increase in plasma triglycerides, a decrease in high density lipoprotein cholesterol and the prevalence of smaller denser low density lipoprotein particles. The prevalence of this partially inheritable phenotype is approximately 30% and is a feature ...

journal_title：Swiss medical weekly

authors： Berneis K,Rizzo M

更新日期：2004-12-18 00:00:00

abstract：PRINCIPLES:3435C>T, a single nucleotide polymorphism (SNP) in exon 26 of the MDR1 gene, is linked to the variability of P-gp expression and function among different individuals. It was found that ethnic differences exist in the polymorphism of the MDR1(C3435T) gene. However, the distribution of 3435C>T genotypes in the...

journal_title：Swiss medical weekly

authors： Li Y,Wang Y,Sun J,Li Y,Yang L

更新日期：2006-06-10 00:00:00

abstract：: ...

journal_title：Swiss medical weekly

authors： Jargin SV

更新日期：2011-03-18 00:00:00

abstract：:Amyloid fibrils are polymers composed of proteins in beta-sheet conformation, which are found in at least 20 diseases for which no cure is available. These diseases include Alzheimer's disease and spongiform encephalopathies, in which the amyloid beta-peptide and the prion protein (PrP), respectively, form amyloid. Al...

journal_title：Swiss medical weekly

authors： Johansson J

更新日期：2003-05-17 00:00:00

abstract：OBJECTIVES:To compare the long-term effects of comprehensive outpatient versus inpatient rehabilitation with respect to morbidity and mortality, as well as to changes in physical performance and physical activity. DESIGN:A total of 163 consecutive patients were enrolled for comprehensive cardiac rehabilitation (CCR) f...

journal_title：Swiss medical weekly

authors： Steinacker JM,Liu Y,Muche R,Koenig W,Hahmann H,Imhof A,Kropf C,Brandstetter S,Schweikert B,Leidl R,Schiefer DH

更新日期：2011-01-06 00:00:00

abstract：AIMS:We aimed to identify familial hypercholesterolaemia mutation carriers among participants to the Lausanne Institutional Biobank (BIL). Our experimental workflow was designed as a proof-of-concept demonstration of the resources and services provided by our integrated institutional clinical research support platform....

journal_title：Swiss medical weekly

authors： Maurer F,Pradervand S,Guilleret I,Nanchen D,Maghraoui A,Chapatte L,Bojkowska K,Bhuiyan ZA,Jacquemont N,Harshman K,Mooser V

更新日期：2016-08-06 00:00:00

abstract：:Current guidelines from the Swiss Association against Osteoporosis (SVGO) dating from 2015 recommend therapy for men and women at increased fracture risk, specifically those with a vertebral or hip fracture; those with bone mineral density T-score <−2.5 at spine or hip; and those with a high 10-year probability ...

journal_title：Swiss medical weekly

authors： Ferrari S,Lippuner K,Lamy O,Meier C

更新日期：2020-09-29 00:00:00

abstract：OBJECTIVES:Epidemological studies suggest that farmers are at an increased risk for chronic obstructive pulmonary disease because of exposure to organic dust. We assessed the proportion of farmers among patients with end stage lung disease and we measured the seasonal exposure of dairy farmers to organic dust in a rura...

journal_title：Swiss medical weekly

authors： Cathomas RL,Brüesch H,Fehr R,Reinhart WH,Kuhn M

更新日期：2002-04-06 00:00:00

abstract：BACKGROUND:Evaluation of the current clinical treatment of psoriasis in Switzerland remains to be measured with the parameters cost-of-illness and quality of life. OBJECTIVE:To obtain data on out-of-pocket expenses, costs of outpatient/office-based care and inpatient care for psoriasis, and to extrapolate total costs ...

journal_title：Swiss medical weekly

authors： Navarini AA,Laffitte E,Conrad C,Piffaretti P,Brock E,Ruckdaeschel S,Trüeb RM

更新日期：2010-02-06 00:00:00

abstract：:The antineutrophil cytoplasmic antibody (ANCA) associated vasculitides (AAV) are a group of primary vasculitides that affect predominantly small- to medium-sized blood vessels. AAV include granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA) and eosinophilic granulomatosis with polyangiitis (EGPA). D...

journal_title：Swiss medical weekly

authors： Daikeler T,Kistler AD,Martin PY,Vogt B,Huynh-Do U

更新日期：2015-02-06 00:00:00

abstract：QUESTIONS UNDER STUDY:Deep brain stimulation (DBS) has become a standard therapy for some forms of severe movement disorders and is investigated for other neurological and psychiatric disorders, although many scientific, clinical and ethical issues are still open. We analyse how the Swiss DBS community addresses these ...

journal_title：Swiss medical weekly

authors： Christen M,Müller S

更新日期：2012-04-05 00:00:00

abstract：:The current situation of the biomedical sciences is critically discussed. It can be summarized as follows: 1. We have to acknowledge the presence of a serious credibility problem, which might undermine the foundations of medical science. ("Sliding on a slippery slope") 2. Multiple forces going beyond simple conflicts ...

journal_title：Swiss medical weekly

authors： Obrist R

更新日期：2015-03-13 00:00:00

abstract：QUESTION UNDER STUDY:What are the trends in avoidable cancer mortality in Switzerland and neighbouring countries? METHODS:Mortality data and population estimates 1996-2010 were obtained from the Swiss Federal Statistical Office for Switzerland and the World Health Organization Mortality Database (http://www.who.int/he...

journal_title：Swiss medical weekly

authors： Feller A,Mark MT,Steiner A,Clough-Gorr KM

更新日期：2015-10-02 00:00:00

abstract：BACKGROUND:B-type natriuretic peptide (BNP) has been proven to be a biochemical marker of severity of congestive heart failure. We are aware of only few papers reporting the association of BNP elevation and pulmonary hypertension (primary, thromboembolic, or as a consequence of chronic obstructive pulmonary disease). L...

journal_title：Swiss medical weekly

authors： Maeder M,Ammann P,Rickli H,Diethelm M

更新日期：2003-09-26 00:00:00

abstract：OBJECTIVES:To determine 1) rates of needlestick and sharps injuries (NSSIs) not reported to occupational health services, 2) reasons for underreporting and 3) awareness of reporting procedures in a Swiss university hospital. MATERIALS AND METHODS:We surveyed 6,367 employees having close clinical contact with patients ...

journal_title：Swiss medical weekly

authors： Voide C,Darling KE,Kenfak-Foguena A,Erard V,Cavassini M,Lazor-Blanchet C

更新日期：2012-02-10 00:00:00

abstract：BACKGROUND:Renal replacement therapy for paediatric end-stage renal disease (ESRD) has developed steadily since its introduction five decades ago. Continuous and long-term analysis of patient outcomes is essential for quality control. METHODS:The Swiss Paediatric Renal Registry, founded in 1970, includes patients diag...

journal_title：Swiss medical weekly

authors： Maurer E,Neuhaus TJ,Weitz M,Kuehni CE,Laube GF

更新日期：2020-07-27 00:00:00

abstract：:Beta-haemolytic streptococci of groups C and G have become increasingly recognized as causes of invasive human infections. We reviewed clinical and molecular characteristics of Streptococcus dysgalactiae isolates that caused bacteraemia in adults from 2006 to 2015. Among 67 episodes, skin and soft-tissue infections (4...

journal_title：Swiss medical weekly

authors： Ruppen C,Rasmussen M,Casanova C,Sendi P

更新日期：2017-07-24 00:00:00

abstract：QUESTIONS UNDER STUDY:To evaluate the diagnostic value of serum Cystatin C and urine neutrophil gelatinase-associated lipocalin (NGAL) for the detection of acute kidney injury in patients undergoing congenital heart surgery. METHODS:Serial samples of serum Cystatin C and urine NGAL were collected from 139 consecutive ...

journal_title：Swiss medical weekly

authors： Seitz S,Rauh M,Gloeckler M,Cesnjevar R,Dittrich S,Koch AM

更新日期：2013-01-17 00:00:00

abstract：BACKGROUND:Sarcoidosis is a disorder of unknown aetiology. Most patients have steroid-responsive disease, but side effects and steroid resistance may necessitate alternative treatments. Endothelin has in-vitro fibrogenic activity and the endothelin system is activated in sarcoidosis. OBJECTIVES:We studied the efficacy...

journal_title：Swiss medical weekly

authors： Hostettler K,Baty F,Kleiner R,Junker L,Tamm M,Brutsche M

更新日期：2018-10-28 00:00:00

abstract：INTRODUCTION:Graft rejection and infection remain major morbidities following orthotopic liver transplantation (OLT). Rejection treatment may be associated with an increased rate of infectious complications. The aim of this study was to determine the relationship between rejection, rejection therapy and the risk of ass...

journal_title：Swiss medical weekly

authors： Garbino J,Romand JA,Pittet D,Giostra E,Mentha G,Suter P

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Neuroendocrine neoplasms (NENs) are difficult to diagnose. We used SwissNET data to characterise NEN patients followed in the two academic centres of western Switzerland (WS), and to compare them with patients followed in eastern Switzerland (ES) as well as with international guidelines. METHOD:SwissNET is ...

journal_title：Swiss medical weekly

authors： Gouffon M,Iff S,Ziegler K,Larche M,Schwarzenbach C,Prior JO,Matter M,Stettler C,Pralong FP

更新日期：2014-02-19 00:00:00

abstract：OBJECTIVES:To investigate the subjective treatment goals of insulin-treated diabetic patients. METHODS:297 type 1 and 205 type 2 diabetic patients, representative of the North-western Swiss population, filled out a self report questionnaire focusing on their own treatment goals using standardized measures wherever ava...

journal_title：Swiss medical weekly

authors： Puder JJ,Endrass J,Moriconi N,Keller U

更新日期：2006-09-02 00:00:00

abstract：:Minimal residual disease (MRD) refers to the small number of malignant cells that remain after therapy when the patient is in remission and shows no symptoms or overt signs of disease. Current treatment protocols for haematological malignancies allow most patients to obtain some form of MRD state, but cure seldom foll...

journal_title：Swiss medical weekly

authors： Hauwel M,Matthes T

更新日期：2014-01-22 00:00:00

abstract：INTRODUCTION:Data suggest that a substantial proportion of psychotherapists engage in therapist-client sex (TCS), violating national and international ethical guidelines. The objective of our study was to find a new and effective starting point for preventive interventions. METHOD:Using an online questionnaire, this s...

journal_title：Swiss medical weekly

authors： Hollwich S,Franke I,Riecher-Rössler A,Reiter-Theil S

更新日期：2015-02-04 00:00:00

abstract：BACKGROUND:since 1999 data from pulmonary hypertension (PH) patients from all PH centres in Switzerland were prospectively collected. We analyse the epidemiological aspects of these data. METHODS:PH was defined as a mean pulmonary artery pressure of >25 mm Hg at rest or >30 mm Hg during exercise. Patients with pulmona...

journal_title：Swiss medical weekly

authors： Tueller C,Stricker H,Soccal P,Tamm M,Aubert JD,Maggiorini M,Zwahlen M,Nicod L,Swiss Society for Pulmonary Hypertension.

更新日期：2008-06-28 00:00:00