Epidemiology of pulmonary hypertension: new data from the Swiss registry.

Abstract:

BACKGROUND:since 1999 data from pulmonary hypertension (PH) patients from all PH centres in Switzerland were prospectively collected. We analyse the epidemiological aspects of these data. METHODS:PH was defined as a mean pulmonary artery pressure of >25 mm Hg at rest or >30 mm Hg during exercise. Patients with pulmonary arterial hypertension (PAH), PH associated with lung diseases, PH due to chronic thrombotic and/or embolic disease (CTEPH), or PH due to miscellaneous disorders were registered. Data from adult patients included between January 1999 and December 2004 were analysed. RESULTS:250 patients were registered (age 58 +/- 16 years, 104 (41%) males). 152 patients (61%) had PAH, 73 (29%) had CTEPH and 18 (7%) had PH associated with lung disease. Patients <50 years (32%) were more likely to have PAH than patients >50 years (76% vs. 53%, p <0.005). Twenty-four patients (10%) were lost to followup, 58 patients (26%) died and 150 (66%) survived without transplantation or thrombendarterectomy. Survivors differed from patients who died in the baseline six-minute walking distance (400 m [300-459] vs. 273 m [174-415]), the functional impairment (NYHA class III/IV 86% vs. 98%), mixed venous saturation (63% [57-68] vs. 56% [50-61]) and right atrial pressure (7 mm Hg [4-11] vs. 11 mm Hg [4-18]). DISCUSSION:PH is a disease affecting adults of all ages. The management of these patients in specialised centres guarantees a high quality of care. Analysis of the registry data could be an instrument for quality control and might help identify weak points in assessment and treatment of these patients.

journal_name

Swiss Med Wkly

journal_title

Swiss medical weekly

authors

Tueller C,Stricker H,Soccal P,Tamm M,Aubert JD,Maggiorini M,Zwahlen M,Nicod L,Swiss Society for Pulmonary Hypertension.

doi

2008/25/smw-11915

subject

Has Abstract

pub_date

2008-06-28 00:00:00

pages

379-84

issue

25-26

eissn

1424-7860

issn

1424-3997

pii

smw-11915

journal_volume

138

pub_type

杂志文章,多中心研究
  • Survey of management of first-ever seizures in a hospital based community.

    abstract:BACKGROUND:Epidemiological studies focusing on first-ever seizures have been carried out mainly on community based populations. However, since hospital populations may display varying clinical features, we prospectively analysed patients with first-ever seizure in a hospital based community to evaluate prognosis and th...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:2004/39/smw-10738

    authors: Kawkabani A,Rossetti AO,Despland PA

    更新日期:2004-10-02 00:00:00

  • Function of natural killer cells in immune defence against human leukaemia.

    abstract::Although progress has been made in the management of acute leukaemias, most patients who fail to respond to front-line therapies with cytostatic agents and stem cell transplantation, or who relapse after an initial response die from progressive disease. Novel treatment modalities exploiting donor-derived natural kille...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:

    authors: Wodnar-Filipowicz A,Kalberer CP

    更新日期:2006-06-10 00:00:00

  • Comparison of the efficacy of two months of treatment with co-trimoxazole plus doxycycline vs. co-trimoxazole plus rifampin in brucellosis.

    abstract:BACKGROUND:To compare the efficacy of two different regimens in treatment of brucellosis. METHODS:This randomised clinical trial study was conducted on 280 patients with brucellosis in Babol, Iran, from April 1999 to January 2002. One of the following two regimens was randomly prescribed for two months: co-trimoxazole...

    journal_title:Swiss medical weekly

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:2004/37/smw-10665

    authors: Roushan MR,Gangi SM,Ahmadi SA

    更新日期:2004-09-18 00:00:00

  • 2020 recommendations for osteoporosis treatment according to fracture risk from the Swiss Association against Osteoporosis (SVGO).

    abstract::Current guidelines from the Swiss Association against Osteoporosis (SVGO) dating from 2015 recommend therapy for men and women at increased fracture risk, specifically those with a vertebral or hip fracture; those with bone mineral density T-score <−2.5 at spine or hip; and those with a high 10-year probability ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2020.20352

    authors: Ferrari S,Lippuner K,Lamy O,Meier C

    更新日期:2020-09-29 00:00:00

  • Giant cell arteritis--a changing entity.

    abstract::Giant cell arteritis (GCA) is the most common of the vasculitis syndromes and, being a disease of the elderly, its incidence is increasing with the general ageing of the population. GCA is most feared for its early complications, namely blindness and stroke, resulting from inflammation and subsequent occlusion of ocul...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:10.4414/smw.2011.13272

    authors: Kesten F,Aschwanden M,Gubser P,Glatz K,Daikeler T,Hess C

    更新日期:2011-09-28 00:00:00

  • Diagnosis and workup of 522 consecutive patients with neuroendocrine neoplasms in Switzerland.

    abstract:BACKGROUND:Neuroendocrine neoplasms (NENs) are difficult to diagnose. We used SwissNET data to characterise NEN patients followed in the two academic centres of western Switzerland (WS), and to compare them with patients followed in eastern Switzerland (ES) as well as with international guidelines. METHOD:SwissNET is ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2014.13924

    authors: Gouffon M,Iff S,Ziegler K,Larche M,Schwarzenbach C,Prior JO,Matter M,Stettler C,Pralong FP

    更新日期:2014-02-19 00:00:00

  • Aortic distensibility alterations in adults with m.3243A>G MELAS gene mutation.

    abstract:PRINCIPLES:MELAS, or mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes is a new distinctive clinical entity. The current study was designed to assess ascending aortic elasticity in adult patients with MELAS syndrome and in gene carriers, and to compare the results with age- and gender-mat...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:smw-12390

    authors: Nemes A,Geleijnse ML,Sluiter W,Vydt TC,Soliman OI,van Dalen BM,Vletter WB,ten Cate FJ,Smeets HJ,de Coo RF

    更新日期:2009-02-21 00:00:00

  • Attitudes towards organ donation and relation to wish to donate posthumously.

    abstract:BACKGROUND:Organs donated for transplantation remain a scarce resource in Switzerland. One of the reasons for this situation is the high percentage of patients or families who refuse to consent to donation. This study aimed to provide an overview of attitudes towards organ donation among Swiss residents, including any ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2017.14401

    authors: Weiss J,Shaw D,Schober R,Abati V,Immer FF,Comité National du Don d'Organes Cndo

    更新日期:2017-02-03 00:00:00

  • Evaluation of prenatal diagnosis of congenital heart disease in a regional controlled case study.

    abstract:AIMS:This study evaluated the evolution of the prenatal diagnosis of congenital heart disease (CHD) between 2003 and 2008 and its repercussion for the CHD prevalence rate at birth in a well-defined population (Canton of Vaud, Switzerland). METHODS AND RESULTS:All 572 cases of CHD reported in the Eurocat Registry of Va...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2014.14068

    authors: Rossier MC,Mivelaz Y,Addor MC,Sekarski N,Meijboom EJ,Vial Y

    更新日期:2014-12-04 00:00:00

  • Illuminating human health through cell mechanics.

    abstract::Cells reside in mechanically rich and dynamic microenvironments, and the complex interplay between mechanics and biology is widely acknowledged. Recent research has yielded insights linking the mechanobiology of cells, human physiology, and pathophysiology. In particular, we have learned of the cell's astounding abili...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:10.4414/smw.2013.13766

    authors: Steward RL Jr,Rosner SR,Zhou EH,Fredberg JJ

    更新日期:2013-03-14 00:00:00

  • Accuracy of doctors' anthropometric measurements in general practice.

    abstract:PURPOSE:There is increasing pressure on general practitioners (GPs) to identify patients with abdominal obesity in order to reduce the life-threatening consequences of this condition in the population. We aimed to confirm previous findings on the inaccuracy of anthropometric measurements performed by GPs in an academic...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2015.14115

    authors: Sebo P,Haller D,Pechère-Bertschi A,Bovier P,Herrmann F

    更新日期:2015-02-21 00:00:00

  • Treatment intensification with insulin glargine in patients with inadequately controlled type 2 diabetes improves glycaemic control with a high treatment satisfaction and no weight gain.

    abstract:PRINCIPLES:We aimed to evaluate the efficacy of, and treatment satisfaction with, insulin glargine administered with SoloSTAR® or ClikSTAR® pens in patients with type 2 diabetes mellitus managed by primary care physicians in Switzerland. METHODS:A total of 327 patients with inadequately controlled type 2 diabetes were...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2015.14114

    authors: Riebenfeld D,Spirk D,Mathis A,Villiger L,Gerber PA,Gasser UE,Lehmann R

    更新日期:2015-03-05 00:00:00

  • Treatment sequence in patients with neuroendocrine tumours: a nationwide multicentre, observational analysis of the Swiss neuroendocrine tumour registry.

    abstract:BACKGROUND:In recent years, several treatment modalities have proved to be effective in the treatment of neuroendocrine tumours (NETs). However, there is currently no consensus on the sequence in which these options are best used. METHODS:In this observational study, we analysed the treatment modalities and sequences ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2020.20176

    authors: Kollar A,Bütikofer L,Ochsenbein A,Stettler C,Trepp R

    更新日期:2020-01-15 00:00:00

  • Describing adverse events in medical inpatients using the Global Trigger Tool.

    abstract:AIMS:The purpose of the study was to describe the type, prevalence, severity and preventability of adverse events (AEs) that affected hospitalised medical patients. We used the previously developed and validated Global Trigger Tool from the Institute for Healthcare Improvement. METHODS:Using an adapted version of the ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2019.20149

    authors: Grossmann N,Gratwohl F,Musy SN,Nielen NM,Simon M,Donzé J

    更新日期:2019-11-10 00:00:00

  • Ovarian cancer in Switzerland: incidence and treatment according to hospital registry data.

    abstract:OBJECTIVE:The methods used to diagnose and classify ovarian cancer have changed over the past decade. We used hospital registry data to assess the incidence, treatment durations and hospital costs of ovarian cancer in Switzerland. METHODS:We carried out a retrospective analysis of a hospital registry covering all inpa...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2018.14647

    authors: Wieser S,Schmidt M,Kind AB,Heinzelmann-Schwarz VA

    更新日期:2018-07-29 00:00:00

  • Daily practice use of Bortezomib in relapsed/refractory multiple myeloma. Safety/efficacy results of a compassionate use program in Switzerland.

    abstract:BACKGROUND:Several publications reported on the safety and efficacy of bortezomib, a novel first-in-class anti-cancer agent, in the treatment of relapsed/refractory multiple myeloma in controlled clinical trials. Complementary data on the experience with bortezomib in daily oncology practice are needed. We report on th...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:2007/21/smw-11716

    authors: Freimann H,Calderoni A,Cornu P,Olie R

    更新日期:2007-06-02 00:00:00

  • Fibroblasts as therapeutic targets in rheumatoid arthritis and cancer.

    abstract::Rheumatoid arthritis is a common chronic inflammatory disease that causes progressive synovial inflammation resulting in irreversible joint destruction, chronic disability and premature mortality. Although it is recognised that in rheumatoid arthritis, inflammation and its persistence result from complex interactions ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:10.4414/smw.2012.13529

    authors: Juarez M,Filer A,Buckley CD

    更新日期:2012-02-24 00:00:00

  • Loss of a preterm infant: psychological aspects in parents.

    abstract:QUESTIONS UNDER STUDY:The unexpected death of a preterm infant is an extremely painful situation for parents. Despite a number of quantitative studies, little is known about parents' inner experience. The aim of this study was to gather more in-depth information about what preoccupies parents in this situation of suffe...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:2007/27/smw-11868

    authors: Glaser A,Bucher HU,Moergeli H,Fauchère JC,Buechi S

    更新日期:2007-07-14 00:00:00

  • Post genomic decade--the epigenome and exposome challenges.

    abstract::Sequencing the human genome was the big challenge of the last decade. Ten years later, the large amount of DNA sequences accumulated in our databases allows us to look at genome variations between humans. The level of complexity of these variations is much higher than previously expected. It goes from changes in the n...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:10.4414/smw.2011.13321

    authors: Paoloni-Giacobino A

    更新日期:2011-12-19 00:00:00

  • Management of fragility fractures in Switzerland: results of a nationwide survey.

    abstract::A nationwide survey was conducted in Switzerland to assess the quality level of osteoporosis management in patients aged 50 years or older presenting with a fragility fracture to the emergency ward of the participating hospitals. Eight centres recruited 4966 consecutive patients who presented with one or more fracture...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:/aop/smw-aop12294

    authors: Suhm N,Lamy O,Lippuner K,OsteoCare study group.

    更新日期:2008-11-15 00:00:00

  • Management of hepatitis C in decentralised versus centralised drug substitution programmes and minimally invasive point-of-care tests to close gaps in the HCV cascade.

    abstract:BACKGROUND:In Switzerland, intravenous drug use accounts for the majority of hepatitis C virus (HCV) infections. Early HCV treatment prevents further transmissions and reduces morbidity and mortality due to decompensated liver cirrhosis and hepatocellular carcinoma. Nevertheless, patients in drug substitution programme...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2017.14544

    authors: Bregenzer A,Conen A,Knuchel J,Friedl A,Eigenmann F,Näf M,Ackle P,Roth M,Fux CA

    更新日期:2017-11-20 00:00:00

  • External radiotherapy for prostate cancer with or without androgen deprivation: Geneva, 1991 to 2004.

    abstract:QUESTIONS UNDER STUDY/PRINCIPLES:A retrospective assessment of long-term results on a single centre, single author experience in treating prostate cancer with high dose curative radiotherapy (RT) with or without androgen deprivation (AD). METHODS:Between 1991 and 2004, 408 patients with clinically localised prostate c...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:smw-12604

    authors: Miralbell R,Pampallona S,Rouzaud M,Pugliesi A,Weber D,Ares C

    更新日期:2009-09-05 00:00:00

  • Procalcitonin: how a hormone became a marker and mediator of sepsis.

    abstract::Calcitonin was discovered in the early 1960s [1], at which time it was assumed to be a single hormone with a yet-to-be-determined role in human physiology. Since then it has been found to be only one entity among a large array of related circulating peptides, at least one of which has a pivotal role in the host respon...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:2001/41/smw-09751

    authors: Müller B,Becker KL

    更新日期:2001-10-20 00:00:00

  • Financial incentives to improve organ donation: what is the opinion of the Vaud French-speaking population?

    abstract:BACKGROUND:With the increase of the organ shortage, several authors assume that financial incentives would improve organ donation rates and fill the unbalance between the demand and the organs available for transplant medicine. This line of argument has been criticised with people arguing that an exchange of money for ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2011.13312

    authors: Bosisio F,Santiago M,Benaroyo L

    更新日期:2011-12-09 00:00:00

  • Vulnerability to relapse under stress: insights from affective neuroscience.

    abstract::In this review article, we aim at analysing the role of stress in addiction and relapse. In order to do so, we first offer a summary of the findings from affective neuroscience trying to understand compulsive reward-seeking behaviours. These behaviours are characterised by an imbalance between the considerable amount ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:10.4414/smw.2019.20151

    authors: Pool ER,Sander D

    更新日期:2019-11-29 00:00:00

  • Renal denervation: time to open Pandora's box.

    abstract::Depending on the populations studied and the definitions applied, the prevalence of treatment-resistant hypertension varies from 10% to 15%, but is higher in conditions associated with increased sympathetic drive, such as obesity, obstructive sleep apnoea, diabetes or renal dysfunction. The Symplicity studies recently...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:10.4414/smw.2012.13638

    authors: Gu YM,Asayama K,Liu YP,Staessen JA

    更新日期:2012-07-17 00:00:00

  • Systematic review of pneumothoraces after endoscopic retrograde cholangiopancreatography.

    abstract:AIMS OF THE STUDY:Pneumothoraces after endoscopic retrograde cholangiopancreatography (ERCP) are an uncommon but potentially lethal complication. Little evidence is available on their epidemiology, diagnosis and therapy. We aimed to evaluate current practices and provide recommendations. METHOD:We systematically revie...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2020.20199

    authors: Lehmann V,Keller W,Egger B

    更新日期:2020-04-03 00:00:00

  • Can geriatric approaches support the care of old patients in emergency departments? A review from a Swiss ED.

    abstract::In the coming decades, old patients will account for an increasing proportion of emergency department (ED) visits. During or after their stay in the ED, they more frequently suffer adverse outcomes than younger patients. There is evidence that specific age-centred approaches improve the outcomes. We therefore reviewed...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:10.4414/smw.2014.14040

    authors: Schoenenberger AW,Exadaktylos AK

    更新日期:2014-12-04 00:00:00

  • Synbiotic preparation in men suffering from functional constipation: a randomised controlled trial.

    abstract:BACKGROUND:Evaluating the effects of a commercially available synbiotic preparation (contains both prebiotic and probiotic elements) on functional constipation in males. METHODS:In a randomised controlled trial, a total of 66 adult men with functional constipation were equally allocated to receive a synbiotic mixture ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,随机对照试验

    doi:10.4414/smw.2011.13239

    authors: Fateh R,Iravani S,Frootan M,Rasouli MR,Saadat S

    更新日期:2011-07-30 00:00:00

  • Undifferentiated carcinoma of nasopharyngeal type (UCNT): a Swiss single-institutional experience during 1990-2005.

    abstract:BACKGROUND:Nasopharyngeal carcinoma is a rare tumor entity in Switzerland. In contrast, it is endemic in Asian and African countries. Retrospective studies have been conducted in order to identify risk factors and prognostic determinants of nasopharyngeal carcinoma. Nonetheless, these trials were mostly conducted in re...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:smw-12844

    authors: Sidler D,Thum P,Winterhalder R,Huber G,Haerle SK

    更新日期:2010-05-01 00:00:00