Abstract:
:Giant cell arteritis (GCA) is the most common of the vasculitis syndromes and, being a disease of the elderly, its incidence is increasing with the general ageing of the population. GCA is most feared for its early complications, namely blindness and stroke, resulting from inflammation and subsequent occlusion of ocular and extra cranial arteries, respectively. More recently, however, GCA has been recognised to also affect limb arteries and the aorta with a high prevalence. These newly recognised features of GCA pose diagnostic, therapeutic and prognostic challenges to treating physicians. Here, recent developments in the field of GCA are summarised and discussed.
journal_name
Swiss Med Wklyjournal_title
Swiss medical weeklyauthors
Kesten F,Aschwanden M,Gubser P,Glatz K,Daikeler T,Hess Cdoi
10.4414/smw.2011.13272subject
Has Abstractpub_date
2011-09-28 00:00:00pages
w13272eissn
1424-7860issn
1424-3997pii
smw-13272journal_volume
141pub_type
杂志文章,评审abstract:BACKGROUND:Although most experts recommend empirical antibiotic treatment, covering also atypical bacteria, for patients admitted to an intensive care unit (ICU), the data are not clear for patients admitted to a general ward. European guidelines recommend starting empirical treatment with a beta-lactam antibiotic with...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2013.13870
更新日期:2013-09-19 00:00:00
abstract::With reference to the Year of the Lung, current knowledge of the respiratory effects of current ambient air pollution is reviewed. Acute respiratory effects are well established. Studies such as SAPALDIA and others now shed light on the long-term effects on chronic pathologies and on the health benefit of air quality ...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:10.4414/smw.2010.13129
更新日期:2010-11-18 00:00:00
abstract:QUESTIONS UNDER STUDY:Suicidal behaviour is a major source of burden of disease. While most studies focus on cost associated with completed suicides, data on costs of, non-lethal, suicide attempts are lacking. The aim of this study was to assess direct annual cost of suicide attempts in Basel in 2003 from a health serv...
journal_title:Swiss medical weekly
pub_type: 杂志文章,多中心研究
doi:10.4414/smw.2012.13648
更新日期:2012-07-23 00:00:00
abstract::Pulmonary arterial hypertension (PAH) is a vascular disease of unknown aetiology, characterised by an abnormal thickening of the arterial wall that is responsible for an increase in pulmonary vascular resistance. The haemodynamic consequence of PAH is an increased afterload for the right ventricle and, eventually, rig...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2016.14305
更新日期:2016-05-31 00:00:00
abstract:AIM OF THE STUDY:In Switzerland, screening concepts for the prevention of sports-associated sudden cardiac death are still insufficiently established in the large group of competitive athletes who are not integrated in an Olympic- or other high-level squad. The aim of the present study was to objectively determine the ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2012.13575
更新日期:2012-05-31 00:00:00
abstract:THEORETICAL BACKGROUND:Mental disorders emerge in childhood and adolescence and are important risk factors for mental disorders in adolescence and adulthood. Since paediatricians are typically the first to see children with psychological problems, the aim of this study was to obtain a survey of mental disorders of chil...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2010.13092
更新日期:2010-08-27 00:00:00
abstract:BACKGROUND:A clinical research application must be submitted for approval by a competent ethics committee (EC) before a study can be executed. There is very limited information on how such submissions could be optimised, especially regarding research in children and adolescents, which requires particular caution and ag...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2020.20267
更新日期:2020-06-19 00:00:00
abstract::After the health catastrophe resulting from the widespread use of asbestos which was once hailed as a new miracle material, the increasing use of carbon nanotubes (CNTs) has spawned major concern due to their similarities in terms of size, shape and poor solubility. Assessment of genotoxicity has shown that CNTs can d...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:10.4414/smw.2012.13698
更新日期:2012-11-05 00:00:00
abstract:OBJECTIVE:To assess the presence of Mycoplasma pneumoniae-associated encephalitis in children in Switzerland and its likely pathogenesis. METHODS:M. pneumoniae-associated encephalitis cases seen at a single-centre during 2010-2013 were reviewed, and the Swiss Paediatric Surveillance Unit (SPSU) prospectively conducted...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2016.14222
更新日期:2016-01-11 00:00:00
abstract:BACKGROUND:Sarcoidosis is a disorder of unknown aetiology. Most patients have steroid-responsive disease, but side effects and steroid resistance may necessitate alternative treatments. Endothelin has in-vitro fibrogenic activity and the endothelin system is activated in sarcoidosis. OBJECTIVES:We studied the efficacy...
journal_title:Swiss medical weekly
pub_type: 杂志文章,随机对照试验
doi:10.4414/smw.2018.14677
更新日期:2018-10-28 00:00:00
abstract:QUESTIONS UNDER STUDY:In view of the alarming trend in childhood obesity (O) and overweight (OW) observed in certain countries, the aim of the study is to measure the prevalence of O and OW in successive cohorts of elementary school children in Geneva. METHODS:All 5-6-year-old children attending public schools in the ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2010.13040
更新日期:2010-07-22 00:00:00
abstract:QUESTIONS UNDER STUDY:Some evidence suggests that a loud voice is a core characteristic of medical professionals. It is unknown whether medical students talk louder than their non-medical peers and, if so, whether they commence their studies with a loud voice, representing a characteristic of admission, or whether soun...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2012.13534
更新日期:2012-03-09 00:00:00
abstract:BACKGROUND:The Swiss Monitoring of Potential Organ Donors (SwissPOD) was initiated to investigate the causes of the overall low organ donation rate in Switzerland. The objective of our study was an assessment of the donation after brain death (DBD) process in Swiss adult intensive care units (ICUs), and to provide an o...
journal_title:Swiss medical weekly
pub_type: 杂志文章,多中心研究
doi:10.4414/smw.2014.14045
更新日期:2014-10-23 00:00:00
abstract:QUESTION UNDER STUDY:The present study aimed to compare the prevalence of work-life conflicts and the health status of physicians, with a representative sample of university graduates as well as with a representative sample of the general Swiss working population. Furthermore, it aimed to analyse whether work-life conf...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2010.13063
更新日期:2010-07-11 00:00:00
abstract:UNLABELLED:In an earlier study in 2002 we showed that of 101 persons applying for a disability pension for psychiatric reasons, a psychiatric diagnosis that affected their ability to work, could only be confirmed in 83%. Furthermore, and even more importantly, only 64% of these cases were receiving any psychiatric trea...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2008/23/smw-12102
更新日期:2008-06-14 00:00:00
abstract::Lung transplantation has now been performed for more than 30 years in patients with end-stage chronic obstructive pulmonary disease (COPD). This disease is the major indication for lung transplantation, involving more than one third of the procedures worldwide. Although lung transplantation in COPD patients has clearl...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:smw-12377
更新日期:2009-01-10 00:00:00
abstract:OBJECTIVE:To provide population-based, gestational age (GA) stratified incidence of mortality and morbidities. METHODS:Population-based prospective observational study of infants born between 23 0/7 and 31 6/7 weeks GA in the years 2000-2004 in all Swiss neonatal intensive care units. Outcomes measured were: mortality...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2011.13212
更新日期:2011-06-24 00:00:00
abstract:QUESTIONS UNDER STUDY:Deep brain stimulation (DBS) has become a standard therapy for some forms of severe movement disorders and is investigated for other neurological and psychiatric disorders, although many scientific, clinical and ethical issues are still open. We analyse how the Swiss DBS community addresses these ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2012.13570
更新日期:2012-04-05 00:00:00
abstract:QUESTIONS UNDER STUDY:In Switzerland, skin cancer is one of the most prevalent neoplasms. General practitioners (GPs) are often faced with suspicious skin lesions in their patients. The aim of our study was to assess GPs' competence to diagnose skin cancer and to examine whether this can be improved by a one-day dermat...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2013.13834
更新日期:2013-07-29 00:00:00
abstract::The precise diagnosis of a severe haemorrhagic disorder is usually not too problematic. However, physicians are most often faced with individuals consulting for mild haemorrhagic symptoms, particularly occurring after a surgical intervention. The problem here is to evaluate whether this person really has a bleeding di...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:smw-12476
更新日期:2009-06-13 00:00:00
abstract:OBJECTIVE:Regular checking of the fitness to drive of elderly car-license holders is required in some countries, and this will become increasingly important as more countries face aging populations. The present study investigated whether the analysis of saccadic eye movements could be used as a screening method for the...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2015.14098
更新日期:2015-02-09 00:00:00
abstract:BACKGROUND:Low-molecular-weight heparins (LMWH) have been shown to be safer, more effective and more convenient than unfractionated heparin (UFH) in many clinical situations. However, their use is limited in patients with renal insufficiency (RI) due to bioaccumulation. METHOD:The literature is critically reviewed and...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:smw-11284
更新日期:2009-08-08 00:00:00
abstract:PURPOSE:Sayana® was introduced as the first depot medroxyprogesterone acetate-containing contraceptive that is administered via subcutaneous injection. Within 10 months, the Regional Pharmacovigilance Centre (RPVC) Zurich received several anonymous reports of serious local reactions after Sayana® administration. In thi...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2017.14432
更新日期:2017-05-10 00:00:00
abstract::This paper focuses on the relationships between schizophrenia and religion, on the basis of a review of literature and the data of an ongoing study about religiousness and spiritual coping conducted among outpatients with chronic schizophrenia. Religion (including both spirituality and religiousness) is salient in the...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:2004/25/smw-10322
更新日期:2004-06-26 00:00:00
abstract:BACKGROUND:The number of individuals with autoimmune inflammatory rheumatic diseases (AIIRDs) treated with immunosuppressive drugs is increasing steadily. The variety of immunosuppressive drugs and, in particular, biological therapies is also rising. The immunosuppressants, as well as the AIIRD itself, increase the ris...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2015.14159
更新日期:2015-07-28 00:00:00
abstract:STUDY/PRINCIPLES:Physical activity improves the clinical course of the metabolic syndrome and its risk factors. The aim of this study was to investigate the physical activity behaviour in patients with metabolic syndrome in regard to the recommendation of the Federal Offices of Public Health (BAG) and Sports (BASPO): "...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2012.13691
更新日期:2012-10-25 00:00:00
abstract::Better recipient selection, sophisticated postoperative surveillance and new immunosuppressive and anti-infective regimens can improve the results of lung transplantation. We compared the results of lung transplants performed between 1992 and 1996 (early period; 47) and between 1997 and 2000 (recent period; 46) in a c...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2001/17/smw-09718
更新日期:2001-05-05 00:00:00
abstract:BACKGROUND:Nasopharyngeal carcinoma is a rare tumor entity in Switzerland. In contrast, it is endemic in Asian and African countries. Retrospective studies have been conducted in order to identify risk factors and prognostic determinants of nasopharyngeal carcinoma. Nonetheless, these trials were mostly conducted in re...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:smw-12844
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:The transition from undergraduate to postgraduate training is a crucial career step for physicians. Several international studies have shown that graduates feel insufficiently prepared to perform various aspects of clinical practice. The publication of a national framework for undergraduate medical education...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2020.20370
更新日期:2020-11-24 00:00:00
abstract:BACKGROUND:High quality chest compression is one of the key factors in successful resuscitation. A high standard of training is therefore decisive. We aimed to investigate the strengths and weaknesses of teaching chest compression in a study designed to highlight where targeted improvements in the quality of our chest ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2011.13221
更新日期:2011-07-01 00:00:00