Function of natural killer cells in immune defence against human leukaemia.

abstract：PRINCIPLES:MELAS, or mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes is a new distinctive clinical entity. The current study was designed to assess ascending aortic elasticity in adult patients with MELAS syndrome and in gene carriers, and to compare the results with age- and gender-mat...

journal_title：Swiss medical weekly

authors： Nemes A,Geleijnse ML,Sluiter W,Vydt TC,Soliman OI,van Dalen BM,Vletter WB,ten Cate FJ,Smeets HJ,de Coo RF

更新日期：2009-02-21 00:00:00

abstract：BACKGROUND:Introduction of potent antiretroviral combination therapy (ART) has reduced overall morbidity and mortality amongst HIV-infected adults. Some prophylactic regimes against opportunistic infections can be discontinued in patients under successful ART. QUESTIONS UNDER STUDY:(1) The influence of the availabilit...

journal_title：Swiss medical weekly

authors： Rossi M,Flepp M,Telenti A,Schiffer V,Egloff N,Bucher H,Vernazza P,Bernasconi E,Weber R,Rickenbach M,Furrer H,Swiss HIV Cohort Study.

更新日期：2001-08-11 00:00:00

abstract：:Kras, a small intracellular GTPase, is a central intermediary of the epidermal growth factor receptor (EGFR) and other tyrosine kinase receptor pathways. Increased EGFR and Kras signalling is involved in colorectal carcinogenesis and tumour progression. Mutations of Kras result in the loss of its GTPase activity and t...

journal_title：Swiss medical weekly

authors： Wicki A,Herrmann R,Christofori G

更新日期：2010-11-19 00:00:00

abstract：:Since 1946 the development of fractionation and purification methods of human plasma led to biologic immunoglobulin for intravenous use (IVIG). In 1980 a child with refractory immune thrombocytopenia (ITP), bleeding and secondary hypogammaglobulinaemia due to long term immunosuppressive treatment got IVIG. His platele...

journal_title：Swiss medical weekly

authors： Imbach P

更新日期：2012-05-31 00:00:00

abstract：:The United Nations General Assembly has convened a Summit on non-communicable diseases (NCDs), an historic moment in the global combat of these disorders. Lifestyles in increasingly urban and globalised environments have led to a steep surge in NCD incidence in low and middle income countries, where two thirds of all ...

journal_title：Swiss medical weekly

authors： Probst-Hensch N,Tanner M,Kessler C,Burri C,Künzli N

更新日期：2011-09-07 00:00:00

abstract：PRINCIPLES:Analysis of the spatial distribution of mortality data is important for identification of high-risk areas, which in turn might guide prevention, and modify behaviour and health resources allocation. This study aimed to update the Swiss mortality atlas by analysing recent data using Bayesian statistical metho...

journal_title：Swiss medical weekly

authors： Chammartin F,Probst-Hensch N,Utzinger J,Vounatsou P

更新日期：2016-02-22 00:00:00

abstract：BACKGROUND:Neuroendocrine neoplasms (NENs) are difficult to diagnose. We used SwissNET data to characterise NEN patients followed in the two academic centres of western Switzerland (WS), and to compare them with patients followed in eastern Switzerland (ES) as well as with international guidelines. METHOD:SwissNET is ...

journal_title：Swiss medical weekly

authors： Gouffon M,Iff S,Ziegler K,Larche M,Schwarzenbach C,Prior JO,Matter M,Stettler C,Pralong FP

更新日期：2014-02-19 00:00:00

abstract：:Our senses are the main information channels through which we perceive and interact with the world. Consequently, the physical and social functioning of patients suffering from severe sensory disabilities is limited on several levels. This has motivated the development of a novel therapeutic alternative: “artifi...

journal_title：Swiss medical weekly

authors： Pérez Fornos A,Van de Berg R,Sommerhalder J,Guinand N

更新日期：2019-06-02 00:00:00

abstract：BACKGROUND:To compare the efficacy of two different regimens in treatment of brucellosis. METHODS:This randomised clinical trial study was conducted on 280 patients with brucellosis in Babol, Iran, from April 1999 to January 2002. One of the following two regimens was randomly prescribed for two months: co-trimoxazole...

journal_title：Swiss medical weekly

authors： Roushan MR,Gangi SM,Ahmadi SA

更新日期：2004-09-18 00:00:00

abstract：:A prominent 2014 series by The Lancet on "Increasing value, reducing waste in biomedical research" provided recommendations on how to optimise precious resources, including in clinical research. Despite being ideally placed to lead the movement in patient-oriented clinical research, academia struggles to take correspo...

journal_title：Swiss medical weekly

authors： von Niederhäusern B,Magnin A,Pauli-Magnus C

更新日期：2018-04-26 00:00:00

abstract：INTRODUCTION:It has been proposed that reactive oxygen species play a role in renal fibrosis. 8-OHdG, a metabolite of oxidative damage to leukocyte DNA, has been identified as a marker of oxidative stress in patients with chronic renal failure. MATERIALS AND METHODS:Seventy-four patients following nephrectomy were ret...

journal_title：Swiss medical weekly

authors： Tsai JP,Liou JH,Yeh KT,Tai HC,Cheng YW,Chang HR

更新日期：2011-10-12 00:00:00

abstract：:The ex utero intrapartum treatment (EXIT) procedure is designed to guarantee sufficient oxygenation for a foetus at risk of airway obstruction. This is achieved by improving lung ventilation, usually by establishing an airway during caesarean delivery whilst preserving the foetal-placental circulation temporarily. Ind...

journal_title：Swiss medical weekly

authors： Kern C,Ange M,Morales,Peiry B,Pfister RE

更新日期：2007-05-19 00:00:00

abstract：INTRODUCTION:Effort-reward imbalance (ERI) and work-life imbalance (WLI) are recognised risk factors for work stress and burnout but have not been investigated conjointly so far and compared with each other in this regard. The present cross-sectional study provides initial evidence by studying associations of ERI and W...

journal_title：Swiss medical weekly

authors： Hämmig O,Brauchli R,Bauer GF

更新日期：2012-05-31 00:00:00

abstract：OBJECTIVES:Epidemological studies suggest that farmers are at an increased risk for chronic obstructive pulmonary disease because of exposure to organic dust. We assessed the proportion of farmers among patients with end stage lung disease and we measured the seasonal exposure of dairy farmers to organic dust in a rura...

journal_title：Swiss medical weekly

authors： Cathomas RL,Brüesch H,Fehr R,Reinhart WH,Kuhn M

更新日期：2002-04-06 00:00:00

abstract：PRINCIPLES:Small dense LDLs have been found to be associated with type 2 diabetes (T2DM). This association has been observed in the context of decreased HDL cholesterol and increased triglycerides. METHODS:In the present study the relationship between LDL particle size and insulin sensitivity was assessed in 46 patien...

journal_title：Swiss medical weekly

authors： Krayenbuehl PA,Wiesli P,Schmid C,Lehmann R,Spinas GA,Berneis K

更新日期：2008-05-03 00:00:00

abstract：:The precise diagnosis of a severe haemorrhagic disorder is usually not too problematic. However, physicians are most often faced with individuals consulting for mild haemorrhagic symptoms, particularly occurring after a surgical intervention. The problem here is to evaluate whether this person really has a bleeding di...

journal_title：Swiss medical weekly

authors： de Moerloose P,Levrat E,Fontana P,Boehlen F

更新日期：2009-06-13 00:00:00

abstract：BACKGROUND:Sarcoidosis is a disorder of unknown aetiology. Most patients have steroid-responsive disease, but side effects and steroid resistance may necessitate alternative treatments. Endothelin has in-vitro fibrogenic activity and the endothelin system is activated in sarcoidosis. OBJECTIVES:We studied the efficacy...

journal_title：Swiss medical weekly

authors： Hostettler K,Baty F,Kleiner R,Junker L,Tamm M,Brutsche M

更新日期：2018-10-28 00:00:00

abstract：:Cells reside in mechanically rich and dynamic microenvironments, and the complex interplay between mechanics and biology is widely acknowledged. Recent research has yielded insights linking the mechanobiology of cells, human physiology, and pathophysiology. In particular, we have learned of the cell's astounding abili...

journal_title：Swiss medical weekly

authors： Steward RL Jr,Rosner SR,Zhou EH,Fredberg JJ

更新日期：2013-03-14 00:00:00

abstract：:Rehabilitation can be referred to as a "black box" because little is known about what specific interventions comprise the rehabilitation process, including patients with spinal cord injury (SCI). Despite that rehabilitation professionals can "see" daily what rehabilitation looks like, the contribution of each interven...

journal_title：Swiss medical weekly

authors： van Hedel HJ

更新日期：2012-09-20 00:00:00

abstract：BACKGROUND:B-type natriuretic peptide (BNP) has been proven to be a biochemical marker of severity of congestive heart failure. We are aware of only few papers reporting the association of BNP elevation and pulmonary hypertension (primary, thromboembolic, or as a consequence of chronic obstructive pulmonary disease). L...

journal_title：Swiss medical weekly

authors： Maeder M,Ammann P,Rickli H,Diethelm M

更新日期：2003-09-26 00:00:00

abstract：PRINCIPLES:Neuroendocrine neoplasms (NENs) are believed to be associated with an increased risk for additional malignancies (AMs). We aimed to (1) assess the occurrence of AM in NEN patients (2) investigate the characteristics and temporal relationship of NEN patients with and without AM. METHODS:The SwissNET registry...

journal_title：Swiss medical weekly

authors： Kollár A,Blank A,Perren A,Bütikofer L,Stettler C,Christ E

更新日期：2016-11-12 00:00:00

abstract：:Vascular procedures are rarely complicated by infection, but if prosthetic vascular graft infection (PVGI) occurs, morbidity and mortality are high. Several patient-related, surgery-related and postoperative risk factors are reported, but they are not well validated. PVGI is due to bacterial colonisation of the wound ...

journal_title：Swiss medical weekly

authors： Hasse B,Husmann L,Zinkernagel A,Weber R,Lachat M,Mayer D

更新日期：2013-01-24 00:00:00

abstract：OBJECTIVE:To investigate whether olfactory performance decreases as a function of the number of pregnancies, previous research having indicated that olfactory function decreases in the course of pregnancy. METHODS:In a prospective study three groups of women were investigated (total n = 93), women who have given birth...

journal_title：Swiss medical weekly

authors： Wohlgemuth C,Beinder E,Ochsenbein-Kölble N,Hummel T

更新日期：2008-08-09 00:00:00

abstract：QUESTION UNDER STUDY:To assess clinical reactions, immune responses and adverse events to undiluted, three- and sixfold diluted Lister strain vaccine stockpiled in Switzerland. METHODS:A prospective, triple-blinded, randomised, parallel group clinical trial was performed. RESULTS:From 2001 to 2007 104 persons with an...

journal_title：Swiss medical weekly

authors： Gassmann R,Engler OB,Steffen R,Alex M,Czerny CP,Mutsch M

更新日期：2008-07-12 00:00:00

abstract：INTRODUCTION:Acute bronchiolitis is the most common lower respiratory tract infection in the first year of life. Current expert opinion and scientific data suggest that pharmaceutical agents have little impact on the natural course of the disease. METHODS:Postal questionnaires were sent to all Swiss paediatricians to ...

journal_title：Swiss medical weekly

authors： Barben J,Hammer J

更新日期：2003-01-11 00:00:00

abstract：STUDY/PRINCIPLES:Physical activity improves the clinical course of the metabolic syndrome and its risk factors. The aim of this study was to investigate the physical activity behaviour in patients with metabolic syndrome in regard to the recommendation of the Federal Offices of Public Health (BAG) and Sports (BASPO): "...

journal_title：Swiss medical weekly

authors： Murer M,Schmied C,Battegay E,Keller DI

更新日期：2012-10-25 00:00:00

abstract：QUESTION UNDER STUDY:The present study aimed to compare the prevalence of work-life conflicts and the health status of physicians, with a representative sample of university graduates as well as with a representative sample of the general Swiss working population. Furthermore, it aimed to analyse whether work-life conf...

journal_title：Swiss medical weekly

authors： Knecht M,Bauer GF,Klaghofer R,Buddeberg-Fischer B,Stamm M,Hämmig O

更新日期：2010-07-11 00:00:00

abstract：INTRODUCTION:Data suggest that a substantial proportion of psychotherapists engage in therapist-client sex (TCS), violating national and international ethical guidelines. The objective of our study was to find a new and effective starting point for preventive interventions. METHOD:Using an online questionnaire, this s...

journal_title：Swiss medical weekly

authors： Hollwich S,Franke I,Riecher-Rössler A,Reiter-Theil S

更新日期：2015-02-04 00:00:00

abstract：:Rheumatoid arthritis is a common chronic inflammatory disease that causes progressive synovial inflammation resulting in irreversible joint destruction, chronic disability and premature mortality. Although it is recognised that in rheumatoid arthritis, inflammation and its persistence result from complex interactions ...

journal_title：Swiss medical weekly

authors： Juarez M,Filer A,Buckley CD

更新日期：2012-02-24 00:00:00

abstract：INTRODUCTION:Graft rejection and infection remain major morbidities following orthotopic liver transplantation (OLT). Rejection treatment may be associated with an increased rate of infectious complications. The aim of this study was to determine the relationship between rejection, rejection therapy and the risk of ass...

journal_title：Swiss medical weekly

authors： Garbino J,Romand JA,Pittet D,Giostra E,Mentha G,Suter P

更新日期：2005-10-01 00:00:00