Kras in metastatic colorectal cancer.

abstract：PURPOSE:Stress ulcer prophylaxis prescriptions might not be sufficiently challenged throughout a patient's stay in an intensive care unit (ICU) and might be erroneously maintained after ICU discharge. This study aimed to determine (1) stress ulcer prophylaxis adequacy in ICU and (2) the proportion of patients recei...

journal_title：Swiss medical weekly

authors： Franchitti M,Piubellini J,Sadeghipour F,Eckert P,Voirol P,Schneider AG

更新日期：2020-08-24 00:00:00

abstract：QUESTION UNDER STUDY:To evaluate the situation of Female Genital Mutilation (FGM) in Switzerland. METHODS:Through a questionnaire, Swiss gynaecologists were asked if they have been confronted to FGMs, if they have been asked to perform infibulations and FGMs. The health representatives (Kantonsärzte/médecins cantonaux...

journal_title：Swiss medical weekly

authors： Jäger F,Schulze S,Hohlfeld P

更新日期：2002-05-18 00:00:00

abstract：BACKGROUND:Epidemiological studies focusing on first-ever seizures have been carried out mainly on community based populations. However, since hospital populations may display varying clinical features, we prospectively analysed patients with first-ever seizure in a hospital based community to evaluate prognosis and th...

journal_title：Swiss medical weekly

authors： Kawkabani A,Rossetti AO,Despland PA

更新日期：2004-10-02 00:00:00

abstract：PRINCIPLES:3435C>T, a single nucleotide polymorphism (SNP) in exon 26 of the MDR1 gene, is linked to the variability of P-gp expression and function among different individuals. It was found that ethnic differences exist in the polymorphism of the MDR1(C3435T) gene. However, the distribution of 3435C>T genotypes in the...

journal_title：Swiss medical weekly

authors： Li Y,Wang Y,Sun J,Li Y,Yang L

更新日期：2006-06-10 00:00:00

abstract：:After the health catastrophe resulting from the widespread use of asbestos which was once hailed as a new miracle material, the increasing use of carbon nanotubes (CNTs) has spawned major concern due to their similarities in terms of size, shape and poor solubility. Assessment of genotoxicity has shown that CNTs can d...

journal_title：Swiss medical weekly

authors： van Berlo D,Clift MJ,Albrecht C,Schins RP

更新日期：2012-11-05 00:00:00

abstract：STUDY/PRINCIPLES:Physical activity improves the clinical course of the metabolic syndrome and its risk factors. The aim of this study was to investigate the physical activity behaviour in patients with metabolic syndrome in regard to the recommendation of the Federal Offices of Public Health (BAG) and Sports (BASPO): "...

journal_title：Swiss medical weekly

authors： Murer M,Schmied C,Battegay E,Keller DI

更新日期：2012-10-25 00:00:00

abstract：QUESTIONS UNDER STUDY:In HIV-infected patients, comprehension of medication instructions is an essential condition for adherence to Highly Active Antiretroviral Therapy (HAART). In this study, we used a self-reported questionnaire to know which sources of medication information HIV-infected patients used and their impa...

journal_title：Swiss medical weekly

authors： Korb-Savoldelli V,Gillaizeau F,Caruba T,Tauckoor A,Prognon P,Durieux P,Sabatier B

更新日期：2012-07-26 00:00:00

abstract：QUESTION UNDER STUDY:Domestic accidents are an important problem in paediatric medicine. This study was designed to gain a better understanding of burn mechanisms and target prevention. METHODS:Children treated for burn lesions in the Department of Paediatric Surgery between August 2004 and August 2005 were included i...

journal_title：Swiss medical weekly

authors： Natterer J,de Buys Roessingh A,Reinberg O,Hohlfeld J

更新日期：2009-09-19 00:00:00

abstract：:According to World Health Organisation estimates 1.1 billion people were overweight or obese worldwide in the year 2000 with the prevalence rapidly increasing. Compelling evidence suggests that excess body weight is a risk factor for several cancer types including cancer of the colon, breast, endometrium, kidney, oeso...

journal_title：Swiss medical weekly

authors： Ceschi M,Gutzwiller F,Moch H,Eichholzer M,Probst-Hensch NM

更新日期：2007-01-27 00:00:00

abstract：:A prominent 2014 series by The Lancet on "Increasing value, reducing waste in biomedical research" provided recommendations on how to optimise precious resources, including in clinical research. Despite being ideally placed to lead the movement in patient-oriented clinical research, academia struggles to take correspo...

journal_title：Swiss medical weekly

authors： von Niederhäusern B,Magnin A,Pauli-Magnus C

更新日期：2018-04-26 00:00:00

abstract：BACKGROUND:Renal replacement therapy for paediatric end-stage renal disease (ESRD) has developed steadily since its introduction five decades ago. Continuous and long-term analysis of patient outcomes is essential for quality control. METHODS:The Swiss Paediatric Renal Registry, founded in 1970, includes patients diag...

journal_title：Swiss medical weekly

authors： Maurer E,Neuhaus TJ,Weitz M,Kuehni CE,Laube GF

更新日期：2020-07-27 00:00:00

abstract：OBJECTIVES:First, to test whether current injury is more closely related to acute intake than to usual consumption patterns, and second, to test whether repeated injury is more closely related to general consumption patterns than to acute intake. METHODS:Screening of alcohol consumption of 7,872 patients enrolling bet...

journal_title：Swiss medical weekly

authors： Gmel G,Givel JC,Yersin B,Daeppen JB

更新日期：2007-11-17 00:00:00

abstract：PRINCIPLES:MELAS, or mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes is a new distinctive clinical entity. The current study was designed to assess ascending aortic elasticity in adult patients with MELAS syndrome and in gene carriers, and to compare the results with age- and gender-mat...

journal_title：Swiss medical weekly

authors： Nemes A,Geleijnse ML,Sluiter W,Vydt TC,Soliman OI,van Dalen BM,Vletter WB,ten Cate FJ,Smeets HJ,de Coo RF

更新日期：2009-02-21 00:00:00

abstract：BACKGROUND:With the increase of the organ shortage, several authors assume that financial incentives would improve organ donation rates and fill the unbalance between the demand and the organs available for transplant medicine. This line of argument has been criticised with people arguing that an exchange of money for ...

journal_title：Swiss medical weekly

authors： Bosisio F,Santiago M,Benaroyo L

更新日期：2011-12-09 00:00:00

abstract：:Switzerland has the longest history of the legal practice of non-physician assisted suicide of any country. Assisted suicide is not very tightly regulated in Switzerland, and almost all assisted suicides are supported by a right-to-die organisation. Our study investigates older adults’ attitudes and behaviour to...

journal_title：Swiss medical weekly

authors： Vilpert S,Bolliger E,Borrat-Besson C,Borasio GD,Maurer J

更新日期：2020-07-01 00:00:00

abstract：:Minimal residual disease (MRD) refers to the small number of malignant cells that remain after therapy when the patient is in remission and shows no symptoms or overt signs of disease. Current treatment protocols for haematological malignancies allow most patients to obtain some form of MRD state, but cure seldom foll...

journal_title：Swiss medical weekly

authors： Hauwel M,Matthes T

更新日期：2014-01-22 00:00:00

abstract：:Patients with a solid organ transplant have increased in numbers and in individual survival in Switzerland over the last decades. As a consequence of long-term immunosuppression, skin cancer in solid organ recipients (SOTRs) has been recognized as an important problem. Screening and education of potential SOTRs about ...

journal_title：Swiss medical weekly

authors： Hofbauer GF,Anliker M,Arnold A,Binet I,Hunger R,Kempf W,Laffitte E,Lapointe AC,Pascual M,Pelloni F,Serra A,SGDV working group for organ transplant recipients.

更新日期：2009-07-25 00:00:00

abstract：BACKGROUND:Many antimicrobial stewardship programmes (ASPs) target the intensive care unit owing to high antimicrobial utilisation. In this review, we summarise and assess the quality of evidence supporting the implementation of various ASP strategies in the intensive care unit setting with a focus on publications betw...

journal_title：Swiss medical weekly

authors： Mertz D,Brooks A,Irfan N,Sung M

更新日期：2015-12-21 00:00:00

abstract：:Idiopathic pulmonary fibrosis (IPF) is a chronic and usually progressive lung disorder of unknown aetiology. Conventional management of patients with IPF has been primarily based on the concept that suppressing inflammation would prevent progression to fibrosis. Although the pathogenesis is incompletely understood, it...

journal_title：Swiss medical weekly

authors： Geiser T

更新日期：2003-07-26 00:00:00

abstract：:Advance directives emerged in the 1960s with the goal of empowering people to exert control over their future medical decisions. However, it has become apparent, over recent years, that advance directives do not sufficiently capture the temporal and relational aspects of planning treatment and care. Advance care plann...

journal_title：Swiss medical weekly

authors： Bosisio F,Jox RJ,Jones L,Rubli Truchard E

更新日期：2018-12-30 00:00:00

abstract：:HMG-CoA reductase inhibitors, or statins, are lipid-lowering agents that have been shown to effectively decrease severe rejection periods and development of transplant coronary artery disease after heart transplantation. Precise regulation of major histocompatibility complex class II (MHC class II) gene expression pla...

journal_title：Swiss medical weekly

authors： Kwak B,Mulhaupt F,Veillard N,Pelli G,Mach F

更新日期：2001-01-27 00:00:00

abstract：:Beta-haemolytic streptococci of groups C and G have become increasingly recognized as causes of invasive human infections. We reviewed clinical and molecular characteristics of Streptococcus dysgalactiae isolates that caused bacteraemia in adults from 2006 to 2015. Among 67 episodes, skin and soft-tissue infections (4...

journal_title：Swiss medical weekly

authors： Ruppen C,Rasmussen M,Casanova C,Sendi P

更新日期：2017-07-24 00:00:00

abstract：:Vascular procedures are rarely complicated by infection, but if prosthetic vascular graft infection (PVGI) occurs, morbidity and mortality are high. Several patient-related, surgery-related and postoperative risk factors are reported, but they are not well validated. PVGI is due to bacterial colonisation of the wound ...

journal_title：Swiss medical weekly

authors： Hasse B,Husmann L,Zinkernagel A,Weber R,Lachat M,Mayer D

更新日期：2013-01-24 00:00:00

abstract：QUESTIONS UNDER STUDY:Teenage and young adult (TYA) cancer patients are faced with the diagnosis during a challenging period of psychosocial development that may affect social outcomes in the long term. Therefore, we aimed to: (1) determine differences in social outcomes between long-term TYA cancer survivors and healt...

journal_title：Swiss medical weekly

authors： Mader L,Vetsch J,Christen S,Baenziger J,Roser K,Dehler S,Michel G

更新日期：2017-03-07 00:00:00

abstract：OBJECTIVE:To assess outcomes 24 months after treatment start for multidrug-resistant tuberculosis (MDR-TB). METHODS:Cohort study of all culture-positive MDR-TB cases notified in Switzerland from 01/2003 to 07/2010. RESULTS:Fifty-one cases were observed, with a median age of 26 years (range 2-56). Twenty-seven were ma...

journal_title：Swiss medical weekly

authors： Helbling P,Altpeter E,Egger JM,Zellweger JP

更新日期：2014-12-04 00:00:00

abstract：:Isolated left ventricular hypertrophy, in the absence of hypertension or aortic stenosis, is commonly attributed to hypertrophic cardiomyopathy (HCM). According to the clinical setting, however, other differential diagnoses should be considered. The diagnosis of cardiac amyloidosis may be very challenging especially w...

journal_title：Swiss medical weekly

authors： Bonvini RF,Camenzind E

更新日期：2004-05-15 00:00:00

abstract：PRINCIPLES:Cardiac myxoma is the most commonly diagnosed cardiac tumour. Infection of herpes simplex virus 1 (HSV1) has been postulated to be a factor for this pathologic entity. The aim of the current study was to evaluate the association between HSV 1 and myxoma occurrence. METHODS:Between 1965 and 2005, 70 patients...

journal_title：Swiss medical weekly

authors： Schurr UP,Berdajs DA,Bode B,Dzemali O,Emmert MY,Genoni M

更新日期：2011-08-26 00:00:00

abstract：AIMS OF THE STUDY:To describe patterns of systemic lupus erythematosus (SLE) care and the clinical effectiveness of belimumab plus standard of care therapy in a real-world clinical setting in Switzerland. METHODS:This multicentre, observational, retrospective cohort study included adults with SLE who initiated belimum...

journal_title：Swiss medical weekly

authors： von Kempis J,Duetsch S,Reuschling N,Villiger R,Villiger PM,Vallelian F,Schaer DJ,Mueller RB

更新日期：2019-03-10 00:00:00

abstract：:In this review article, we aim at analysing the role of stress in addiction and relapse. In order to do so, we first offer a summary of the findings from affective neuroscience trying to understand compulsive reward-seeking behaviours. These behaviours are characterised by an imbalance between the considerable amount ...

journal_title：Swiss medical weekly

authors： Pool ER,Sander D

更新日期：2019-11-29 00:00:00

abstract：INTRODUCTION:Effort-reward imbalance (ERI) and work-life imbalance (WLI) are recognised risk factors for work stress and burnout but have not been investigated conjointly so far and compared with each other in this regard. The present cross-sectional study provides initial evidence by studying associations of ERI and W...

journal_title：Swiss medical weekly

authors： Hämmig O,Brauchli R,Bauer GF

更新日期：2012-05-31 00:00:00