Mortality atlas of the main causes of death in Switzerland, 2008-2012.

abstract：:The endoplasmic reticulum (ER) is an intracellular compartment dedicated to the synthesis and maturation of secretory and membrane proteins, totalling about 30% of the total eukaryotic cells proteome. The capacity to produce correctly folded polypeptides and to transport them to their correct intra- or extracellular d...

journal_title：Swiss medical weekly

authors： Noack J,Brambilla Pisoni G,Molinari M

更新日期：2014-08-21 00:00:00

abstract：PURPOSE:Stress ulcer prophylaxis prescriptions might not be sufficiently challenged throughout a patient's stay in an intensive care unit (ICU) and might be erroneously maintained after ICU discharge. This study aimed to determine (1) stress ulcer prophylaxis adequacy in ICU and (2) the proportion of patients recei...

journal_title：Swiss medical weekly

authors： Franchitti M,Piubellini J,Sadeghipour F,Eckert P,Voirol P,Schneider AG

更新日期：2020-08-24 00:00:00

abstract：BACKGROUND:With its high incidence and subsequent adverse consequences in the intensive care setting, several instruments have been developed to screen for and detect delirium. One of the more commonly used is the Intensive Care Delirium Screening Checklist (ICDSC); however, the optimal cut-off score indicating deliriu...

journal_title：Swiss medical weekly

authors： Boettger S,Garcia Nuñez D,Meyer R,Richter A,Rudiger A,Schubert M,Jenewein J

更新日期：2018-03-14 00:00:00

abstract：AIMS:We aimed to identify familial hypercholesterolaemia mutation carriers among participants to the Lausanne Institutional Biobank (BIL). Our experimental workflow was designed as a proof-of-concept demonstration of the resources and services provided by our integrated institutional clinical research support platform....

journal_title：Swiss medical weekly

authors： Maurer F,Pradervand S,Guilleret I,Nanchen D,Maghraoui A,Chapatte L,Bojkowska K,Bhuiyan ZA,Jacquemont N,Harshman K,Mooser V

更新日期：2016-08-06 00:00:00

abstract：PRINCIPLES:Heart failure is associated with a grim prognosis. Disease management programmes can improve prognosis in heart failure patients but the applicability to the general population remains limited. We aimed to compare the outcome, pharmacological therapy, and quality of life in unselected heart failure patients ...

journal_title：Swiss medical weekly

authors： Lainscak M,Keber I

更新日期：2006-04-29 00:00:00

abstract：QUESTIONS UNDER STUDY:Teenage and young adult (TYA) cancer patients are faced with the diagnosis during a challenging period of psychosocial development that may affect social outcomes in the long term. Therefore, we aimed to: (1) determine differences in social outcomes between long-term TYA cancer survivors and healt...

journal_title：Swiss medical weekly

authors： Mader L,Vetsch J,Christen S,Baenziger J,Roser K,Dehler S,Michel G

更新日期：2017-03-07 00:00:00

abstract：OBJECTIVE:To provide population-based, gestational age (GA) stratified incidence of mortality and morbidities. METHODS:Population-based prospective observational study of infants born between 23 0/7 and 31 6/7 weeks GA in the years 2000-2004 in all Swiss neonatal intensive care units. Outcomes measured were: mortality...

journal_title：Swiss medical weekly

authors： Bajwa NM,Berner M,Worley S,Pfister RE,Swiss Neonatal Network.

更新日期：2011-06-24 00:00:00

abstract：BACKGROUND:The principality of Liechtenstein had its first COVID-19 case at the beginning of March 2020. After exponential growth, the pandemic’s first wave was contained, with the last case being diagnosed 52 days after the initial occurrence. AIM:To characterise the COVID-19 pandemic in Liechtenstein. METHODS...

journal_title：Swiss medical weekly

authors： Thiel SL,Weber MC,Risch L,Wohlwend N,Lung T,Hillmann D,Ritzler M,Risch M,Kohler P,Vernazza P,Kahlert CR,Fleisch F,Cusini A,Karajan TV,Copeland S,Paprotny M

更新日期：2020-10-16 00:00:00

abstract：:Amyloid fibrils are polymers composed of proteins in beta-sheet conformation, which are found in at least 20 diseases for which no cure is available. These diseases include Alzheimer's disease and spongiform encephalopathies, in which the amyloid beta-peptide and the prion protein (PrP), respectively, form amyloid. Al...

journal_title：Swiss medical weekly

authors： Johansson J

更新日期：2003-05-17 00:00:00

abstract：BACKGROUND:Adverse reactions to nonsteroidal antiinflammatory drugs (NSAIDs) are frequently reported, particularly among asthmatic patients. To date, there is no causal treatment available apart from tolerance induction. Therefore, the search for safe alternative drugs is of pivotal importance in clinical practice. OB...

journal_title：Swiss medical weekly

authors： Roll A,Wüthrich B,Schmid-Grendelmeier P,Hofbauer G,Ballmer-Weber BK

更新日期：2006-10-28 00:00:00

abstract：:Better recipient selection, sophisticated postoperative surveillance and new immunosuppressive and anti-infective regimens can improve the results of lung transplantation. We compared the results of lung transplants performed between 1992 and 1996 (early period; 47) and between 1997 and 2000 (recent period; 46) in a c...

journal_title：Swiss medical weekly

authors： Speich R,Boehler A,Zalunardo MP,Stocker R,Russi EW,Weder W

更新日期：2001-05-05 00:00:00

abstract：PRINCIPLES:Neuroendocrine neoplasms (NENs) are believed to be associated with an increased risk for additional malignancies (AMs). We aimed to (1) assess the occurrence of AM in NEN patients (2) investigate the characteristics and temporal relationship of NEN patients with and without AM. METHODS:The SwissNET registry...

journal_title：Swiss medical weekly

authors： Kollár A,Blank A,Perren A,Bütikofer L,Stettler C,Christ E

更新日期：2016-11-12 00:00:00

abstract：OBJECTIVES:Tonsillectomy is one of the most frequently performed surgical procedures. Nevertheless there is less known about the impact of this procedure on Health-Related Quality of life (HRQOL). The two different most common used surgical techniques are "cold" (CT) and "hot" (HT) tonsillectomy. The aim of this study ...

journal_title：Swiss medical weekly

authors： Schwentner I,Höfer S,Schmutzhard J,Deibl M,Sprinzl GM

更新日期：2007-08-11 00:00:00

abstract：:Sequencing the human genome was the big challenge of the last decade. Ten years later, the large amount of DNA sequences accumulated in our databases allows us to look at genome variations between humans. The level of complexity of these variations is much higher than previously expected. It goes from changes in the n...

journal_title：Swiss medical weekly

authors： Paoloni-Giacobino A

更新日期：2011-12-19 00:00:00

abstract：QUESTIONS UNDER STUDY:In the next Swiss National HIV and Sexually Transmitted Infection (STI) Strategy 2011-2017, STI control will be integrated with HIV prevention. Information is needed which will improve the targeting of professional education. The objective of this study was to describe the clinical specialities an...

journal_title：Swiss medical weekly

authors： Baillif A,Low N

更新日期：2011-01-20 00:00:00

abstract：UNLABELLED:In an earlier study in 2002 we showed that of 101 persons applying for a disability pension for psychiatric reasons, a psychiatric diagnosis that affected their ability to work, could only be confirmed in 83%. Furthermore, and even more importantly, only 64% of these cases were receiving any psychiatric trea...

journal_title：Swiss medical weekly

authors： Apfel T,Richer-Rössler A

更新日期：2008-06-14 00:00:00

abstract：:Kras, a small intracellular GTPase, is a central intermediary of the epidermal growth factor receptor (EGFR) and other tyrosine kinase receptor pathways. Increased EGFR and Kras signalling is involved in colorectal carcinogenesis and tumour progression. Mutations of Kras result in the loss of its GTPase activity and t...

journal_title：Swiss medical weekly

authors： Wicki A,Herrmann R,Christofori G

更新日期：2010-11-19 00:00:00

abstract：INTRODUCTION:In general practice, the diagnosis of dementia is often delayed. Therefore, the Swiss National Dementia Strategy 2014 concluded that action was needed to improve patient care. Little is known about GPs’ confidence in and approach to the diagnosis, disclosure and post-diagnostic management of individu...

journal_title：Swiss medical weekly

authors： Giezendanner S,Monsch AU,Kressig RW,Mueller Y,Streit S,Essig S,Zeller A,Bally K

更新日期：2018-12-21 00:00:00

abstract：QUESTIONS UNDER STUDY:To evaluate the diagnostic value of serum Cystatin C and urine neutrophil gelatinase-associated lipocalin (NGAL) for the detection of acute kidney injury in patients undergoing congenital heart surgery. METHODS:Serial samples of serum Cystatin C and urine NGAL were collected from 139 consecutive ...

journal_title：Swiss medical weekly

authors： Seitz S,Rauh M,Gloeckler M,Cesnjevar R,Dittrich S,Koch AM

更新日期：2013-01-17 00:00:00

abstract：:Pulmonary rehabilitation is a form of therapy for patients with chronic lung disease that is evidence based, which ameliorates performance and endurance of the patient and improves quality of life significantly. Pulmonary rehabilitation also diminishes the amount of hospitalisations and the duration of stay in hospita...

journal_title：Swiss medical weekly

authors： Karrer W

更新日期：2005-02-05 00:00:00

abstract：PRINCIPLES:Data on associations between physical activity and gastroesophageal reflux disease (GERD) have been inconsistent. Although experimental and clinical studies prove that exercise increases gastroesophageal reflux, epidemiological observations on the relationship between GERD and everyday physical effort delive...

journal_title：Swiss medical weekly

authors： Jóźków P,Waśko-Czopnik D,Dunajska K,Medraś M,Paradowski L

更新日期：2007-08-25 00:00:00

abstract：BACKGROUND:Up to 30% of patients with chronic obstructive pulmonary disease (COPD) simultaneously suffer from often-unrecognised chronic heart failure (HF). Their timely identification is challenging as both conditions share similar clinical presentations. OBJECTIVE:To assess the performance of BNP in detecting left v...

journal_title：Swiss medical weekly

authors： Gariani K,Delabays A,Perneger TV,Agoritsas T

更新日期：2011-11-09 00:00:00

abstract：OBJECTIVES AND METHODS:Gender differences regarding 17 childhood experiences, thought to have traumatising potential (Traumatic Childhood Experiences = TCE), and pain behaviour in adulthood were assessed using a self-administered, anonymously filled-out questionnaire. Patients were consecutively accrued in the offices ...

journal_title：Swiss medical weekly

authors： Unternährer I,Minder CE,Adler RH

更新日期：2006-09-30 00:00:00

abstract：:HMG-CoA reductase inhibitors, or statins, are lipid-lowering agents that have been shown to effectively decrease severe rejection periods and development of transplant coronary artery disease after heart transplantation. Precise regulation of major histocompatibility complex class II (MHC class II) gene expression pla...

journal_title：Swiss medical weekly

authors： Kwak B,Mulhaupt F,Veillard N,Pelli G,Mach F

更新日期：2001-01-27 00:00:00

abstract：BACKGROUND:Based on a reduction in morbidity and mortality, cardiac resynchronisation therapy (CRT) has evolved as a standard therapy for patients with advanced heart failure. OBJECTIVE:To provide insight into patient demographics, safety, echocardiographic remodelling and long-term follow-up of patients treated with ...

journal_title：Swiss medical weekly

authors： Winnik S,Elsener C,Seifert B,Starck C,Straub A,Saguner AM,Breitenstein A,Krasniqi N,Wilhelm MJ,Haegeli L,Duru F,Benussi S,Maisano F,Lüscher TF,Holzmeister J,Huerlimann D,Ruschitzka F,Steffel J

更新日期：2017-04-18 00:00:00

abstract：:This article discusses communication challenges in end-of-life decision making and outlines strategies from an area of growing interest and research. ...

journal_title：Swiss medical weekly

authors： Becker C,Beck K,Vincent A,Hunziker S

更新日期：2020-09-18 00:00:00

abstract：QUESTION UNDER STUDY:The present study aimed to compare the prevalence of work-life conflicts and the health status of physicians, with a representative sample of university graduates as well as with a representative sample of the general Swiss working population. Furthermore, it aimed to analyse whether work-life conf...

journal_title：Swiss medical weekly

authors： Knecht M,Bauer GF,Klaghofer R,Buddeberg-Fischer B,Stamm M,Hämmig O

更新日期：2010-07-11 00:00:00

abstract：QUESTIONS UNDER STUDY/PRINCIPLES:Although probe-based confocal laser endomicroscopy (pCLE) is on the edge of entering daily practice in gastroenterological endoscopy, findings in the field of respiratory medicine are only rarely reported, keeping pCLE during flexible bronchoscopy as a mere preclinical research tool. Si...

journal_title：Swiss medical weekly

authors： Yserbyt J,Dooms C,Ninane V,Decramer M,Verleden G

更新日期：2013-03-26 00:00:00

abstract：:Meningitis due to Streptococcus pneumoniae is a rare complication of trans-sphenoidal surgery. We present the case of a patient who developed pneumococcal meningitis with associated bacteraemia after elective endoscopic trans-sphenoidal resection of a pituitary macro-adenoma. After initial treatment with ceftriaxone a...

journal_title：Swiss medical weekly

authors： Darling KE,Niederhauser J,Bervini D,Giulieri S,Daniel RT,Bille J,Erard V

更新日期：2012-10-29 00:00:00

abstract：:Switzerland has the longest history of the legal practice of non-physician assisted suicide of any country. Assisted suicide is not very tightly regulated in Switzerland, and almost all assisted suicides are supported by a right-to-die organisation. Our study investigates older adults’ attitudes and behaviour to...

journal_title：Swiss medical weekly

authors： Vilpert S,Bolliger E,Borrat-Besson C,Borasio GD,Maurer J

更新日期：2020-07-01 00:00:00