Bosentan for patients with steroid-resistant pulmonary sarcoidosis: a randomised controlled trial.

abstract：BACKGROUND:A clinical research application must be submitted for approval by a competent ethics committee (EC) before a study can be executed. There is very limited information on how such submissions could be optimised, especially regarding research in children and adolescents, which requires particular caution and ag...

journal_title：Swiss medical weekly

authors： Bergstraesser E,Nadal D,Özgü H,Kleist P

更新日期：2020-06-19 00:00:00

abstract：PRINCIPLES:Small dense LDLs have been found to be associated with type 2 diabetes (T2DM). This association has been observed in the context of decreased HDL cholesterol and increased triglycerides. METHODS:In the present study the relationship between LDL particle size and insulin sensitivity was assessed in 46 patien...

journal_title：Swiss medical weekly

authors： Krayenbuehl PA,Wiesli P,Schmid C,Lehmann R,Spinas GA,Berneis K

更新日期：2008-05-03 00:00:00

abstract：BACKGROUND:In recent years, several treatment modalities have proved to be effective in the treatment of neuroendocrine tumours (NETs). However, there is currently no consensus on the sequence in which these options are best used. METHODS:In this observational study, we analysed the treatment modalities and sequences ...

journal_title：Swiss medical weekly

authors： Kollar A,Bütikofer L,Ochsenbein A,Stettler C,Trepp R

更新日期：2020-01-15 00:00:00

abstract：PRINCIPLES:Heart failure is associated with a grim prognosis. Disease management programmes can improve prognosis in heart failure patients but the applicability to the general population remains limited. We aimed to compare the outcome, pharmacological therapy, and quality of life in unselected heart failure patients ...

journal_title：Swiss medical weekly

authors： Lainscak M,Keber I

更新日期：2006-04-29 00:00:00

abstract：:Patients with a solid organ transplant have increased in numbers and in individual survival in Switzerland over the last decades. As a consequence of long-term immunosuppression, skin cancer in solid organ recipients (SOTRs) has been recognized as an important problem. Screening and education of potential SOTRs about ...

journal_title：Swiss medical weekly

authors： Hofbauer GF,Anliker M,Arnold A,Binet I,Hunger R,Kempf W,Laffitte E,Lapointe AC,Pascual M,Pelloni F,Serra A,SGDV working group for organ transplant recipients.

更新日期：2009-07-25 00:00:00

abstract：:Isolated left ventricular hypertrophy, in the absence of hypertension or aortic stenosis, is commonly attributed to hypertrophic cardiomyopathy (HCM). According to the clinical setting, however, other differential diagnoses should be considered. The diagnosis of cardiac amyloidosis may be very challenging especially w...

journal_title：Swiss medical weekly

authors： Bonvini RF,Camenzind E

更新日期：2004-05-15 00:00:00

abstract：QUESTIONS UNDER STUDY:In Switzerland, skin cancer is one of the most prevalent neoplasms. General practitioners (GPs) are often faced with suspicious skin lesions in their patients. The aim of our study was to assess GPs' competence to diagnose skin cancer and to examine whether this can be improved by a one-day dermat...

journal_title：Swiss medical weekly

authors： Badertscher N,Braun RP,Held U,Kofmehl R,Senn O,Hofbauer GF,Rossi PO,Wensing M,Rosemann T,Tandjung R

更新日期：2013-07-29 00:00:00

abstract：BACKGROUND:Evaluation of the current clinical treatment of psoriasis in Switzerland remains to be measured with the parameters cost-of-illness and quality of life. OBJECTIVE:To obtain data on out-of-pocket expenses, costs of outpatient/office-based care and inpatient care for psoriasis, and to extrapolate total costs ...

journal_title：Swiss medical weekly

authors： Navarini AA,Laffitte E,Conrad C,Piffaretti P,Brock E,Ruckdaeschel S,Trüeb RM

更新日期：2010-02-06 00:00:00

abstract：:Osteoporosis is complicated by the occurrence of fragility fractures. Over past years, various treatment options have become available, mostly potent antiresorptive agents such as bisphosphonates and denosumab. However, antiresorptive therapy cannot fully and rapidly restore bone mass and structure that has been lost ...

journal_title：Swiss medical weekly

authors： Meier C,Lamy O,Krieg MA,Mellinghoff HU,Felder M,Ferrari S,Rizzoli R

更新日期：2014-06-04 00:00:00

abstract：BACKGROUND:Carbon monoxide (CO) poisoning is associated with a wide range of non-specific symptoms, whose time course and prognostic significance are ill defined. METHODS:We observed a large CO poisoning in a homogenous cohort of 38 male recruits and compared their symptoms with those of 46 unexposed controls from the...

journal_title：Swiss medical weekly

authors： Henz S,Maeder M

更新日期：2005-07-09 00:00:00

abstract：QUESTION UNDER STUDY:Purpose was to validate accuracy and reliability of automated oscillometric ankle-brachial (ABI) measurement prospectively against the current gold standard of Doppler-assisted ABI determination. METHODS:Oscillometric ABI was measured in 50 consecutive patients with peripheral arterial disease (n ...

journal_title：Swiss medical weekly

authors： Diehm N,Dick F,Czuprin C,Lawall H,Baumgartner I,Diehm C

更新日期：2009-06-27 00:00:00

abstract：:Each year, over 5 million people die worldwide from stroke, and at least every sixth patient who survives will experience another stroke within five years [1]. We are therefore eager to advance early and rapid diagnosis, prognosis and optimal risk stratification, as well as secondary prevention. In this context, blood...

journal_title：Swiss medical weekly

authors： Sonderer J,Katan Kahles M

更新日期：2015-05-29 00:00:00

abstract：BACKGROUND:With the increase of the organ shortage, several authors assume that financial incentives would improve organ donation rates and fill the unbalance between the demand and the organs available for transplant medicine. This line of argument has been criticised with people arguing that an exchange of money for ...

journal_title：Swiss medical weekly

authors： Bosisio F,Santiago M,Benaroyo L

更新日期：2011-12-09 00:00:00

abstract：PURPOSE:Stress ulcer prophylaxis prescriptions might not be sufficiently challenged throughout a patient's stay in an intensive care unit (ICU) and might be erroneously maintained after ICU discharge. This study aimed to determine (1) stress ulcer prophylaxis adequacy in ICU and (2) the proportion of patients recei...

journal_title：Swiss medical weekly

authors： Franchitti M,Piubellini J,Sadeghipour F,Eckert P,Voirol P,Schneider AG

更新日期：2020-08-24 00:00:00

abstract：QUESTIONS UNDER STUDY:Teenage and young adult (TYA) cancer patients are faced with the diagnosis during a challenging period of psychosocial development that may affect social outcomes in the long term. Therefore, we aimed to: (1) determine differences in social outcomes between long-term TYA cancer survivors and healt...

journal_title：Swiss medical weekly

authors： Mader L,Vetsch J,Christen S,Baenziger J,Roser K,Dehler S,Michel G

更新日期：2017-03-07 00:00:00

abstract：:Cartilage hair hypoplasia (CHH) is a rare autosomal recessive ribosomopathy characterised by skeletal and integumentary system manifestations. It may also present with varied forms and intensities of haematopoietic and/or immune disorders. We report a 27-year-old female who presented a picture of combined immunodefici...

journal_title：Swiss medical weekly

authors： Nguyen A,Martin Silva N,de Boysson H,Damaj G,Aouba A

更新日期：2018-04-24 00:00:00

abstract：AIMS OF THE STUDY:The Cancer Registry Zurich, Zug, Schaffhausen and Schwyz is one of the oldest cancer registries in Switzerland, first registering tumours in 1980 for the canton of Zurich. The aim of this study was to analyse trends in incidence and mortality for the most common types of cancer in the canton of Zurich...

journal_title：Swiss medical weekly

authors： Wanner M,Matthes KL,Karavasiloglou N,Limam M,Korol D,Rohrmann S

更新日期：2020-12-14 00:00:00

abstract：BACKGROUND:In contrast to quality of life, patient satisfaction on chronic haemodialysis (HD) and peritoneal dialysis (PD) has only rarely been studied. PATIENTS AND METHODS:All chronic HD and PD patients of the 19 centres located in western Switzerland were asked to complete a specific questionnaire, assessing dialys...

journal_title：Swiss medical weekly

authors： Wasserfallen JB,Moinat M,Halabi G,Saudan P,Perneger T,Feldman HI,Martin PY,Wauters JP

更新日期：2006-04-01 00:00:00

abstract：QUESTIONS UNDER STUDY:Optimal oxygen saturation (SpO2) targets for extremely low gestational age neonates (ELGANs, gestational age [GA] <28 weeks) are unknown. Conflicting results from five recently published multicentre trials, which randomised ELGANs to high (91 to 95%) or low (85 to 89%) SpO2 targets from birth up t...

journal_title：Swiss medical weekly

authors： Hergenhan A,Steurer M,Berger TM

更新日期：2015-11-02 00:00:00

abstract：:Apart from the degree of stenosis, plaque morphology has emerged in recent years as an important contributory factor in stroke risk. Ultrasound studies have shown that hypo- or anechogenic plaques carry a higher risk of cerebrovascular events than echogenic ones. Similarly, heterogeneous plaques presenting a complex p...

journal_title：Swiss medical weekly

authors： Sztajzel R

更新日期：2005-10-29 00:00:00

abstract：:Perinatal care of pregnant women at high risk for preterm delivery and of preterm infants born at the limit of viability (22-26 completed weeks of gestation) requires a multidisciplinary approach by an experienced perinatal team. Limited precision in the determination of both gestational age and foetal weight, as well...

journal_title：Swiss medical weekly

authors： Berger TM,Bernet V,El Alama S,Fauchère JC,Hösli I,Irion O,Kind C,Latal B,Nelle M,Pfister RE,Surbek D,Truttmann AC,Wisser J,Zimmermann R

更新日期：2011-10-18 00:00:00

abstract：PRINCIPLES:Current evidence indicates that chronic kidney disease (CKD) can be detected by simple laboratory tests. This study aimed to evaluate the cost-effectiveness of microalbuminuria screening and subsequent treatment in different populations. METHODS:Cost-effectiveness of microalbuminuria screening in a cohort o...

journal_title：Swiss medical weekly

authors： Kessler R,Keusch G,Szucs TD,Wittenborn JS,Hoerger TJ,Brügger U,Wieser S

更新日期：2012-02-03 00:00:00

abstract：:In his 1966 monograph "Charcot joints", Sidney N. Eichenholtz (1909-2000) described "three well defined stages … in the course and development of a Charcot joint", based on plain X-rays of 68 patients. Since then, medical imaging has advanced very much: computed tomography and magnetic resonance imaging (MRI) scans ex...

journal_title：Swiss medical weekly

authors： Chantelau EA,Grützner G

更新日期：2014-04-24 00:00:00

abstract：INTRODUCTION:In general practice, the diagnosis of dementia is often delayed. Therefore, the Swiss National Dementia Strategy 2014 concluded that action was needed to improve patient care. Little is known about GPs’ confidence in and approach to the diagnosis, disclosure and post-diagnostic management of individu...

journal_title：Swiss medical weekly

authors： Giezendanner S,Monsch AU,Kressig RW,Mueller Y,Streit S,Essig S,Zeller A,Bally K

更新日期：2018-12-21 00:00:00

abstract：QUESTIONS UNDER STUDY:Measuring the patient safety climate in the organisation of healthcare can help to identify problematic issues with a view to improving patient safety. We aimed (1) to describe the nurse-reported engagement in safety behaviours, (2) to describe the prevailing nurse-reported patient safety climate ...

journal_title：Swiss medical weekly

authors： Ausserhofer D,Schubert M,Engberg S,Blegen M,De G,Schwendimann R

更新日期：2012-01-20 00:00:00

abstract：:Cells reside in mechanically rich and dynamic microenvironments, and the complex interplay between mechanics and biology is widely acknowledged. Recent research has yielded insights linking the mechanobiology of cells, human physiology, and pathophysiology. In particular, we have learned of the cell's astounding abili...

journal_title：Swiss medical weekly

authors： Steward RL Jr,Rosner SR,Zhou EH,Fredberg JJ

更新日期：2013-03-14 00:00:00

abstract：:Since 1946 the development of fractionation and purification methods of human plasma led to biologic immunoglobulin for intravenous use (IVIG). In 1980 a child with refractory immune thrombocytopenia (ITP), bleeding and secondary hypogammaglobulinaemia due to long term immunosuppressive treatment got IVIG. His platele...

journal_title：Swiss medical weekly

authors： Imbach P

更新日期：2012-05-31 00:00:00

abstract：:Depending on the populations studied and the definitions applied, the prevalence of treatment-resistant hypertension varies from 10% to 15%, but is higher in conditions associated with increased sympathetic drive, such as obesity, obstructive sleep apnoea, diabetes or renal dysfunction. The Symplicity studies recently...

journal_title：Swiss medical weekly

authors： Gu YM,Asayama K,Liu YP,Staessen JA

更新日期：2012-07-17 00:00:00

abstract：:Calcitonin was discovered in the early 1960s [1], at which time it was assumed to be a single hormone with a yet-to-be-determined role in human physiology. Since then it has been found to be only one entity among a large array of related circulating peptides, at least one of which has a pivotal role in the host respon...

journal_title：Swiss medical weekly

authors： Müller B,Becker KL

更新日期：2001-10-20 00:00:00

abstract：OBJECTIVES:To compare the long-term effects of comprehensive outpatient versus inpatient rehabilitation with respect to morbidity and mortality, as well as to changes in physical performance and physical activity. DESIGN:A total of 163 consecutive patients were enrolled for comprehensive cardiac rehabilitation (CCR) f...

journal_title：Swiss medical weekly

authors： Steinacker JM,Liu Y,Muche R,Koenig W,Hahmann H,Imhof A,Kropf C,Brandstetter S,Schweikert B,Leidl R,Schiefer DH

更新日期：2011-01-06 00:00:00