Abstract:
BACKGROUND:Carbon monoxide (CO) poisoning is associated with a wide range of non-specific symptoms, whose time course and prognostic significance are ill defined. METHODS:We observed a large CO poisoning in a homogenous cohort of 38 male recruits and compared their symptoms with those of 46 unexposed controls from the same military unit. Incident and prevalent symptoms were assessed by sequential questionnaires. FINDINGS:Carboxyhaemoglobin (COHb) concentration extrapolated to the time of rescue was 30.4 +/- 6.1%. Six recruits were initially unconscious, and five others were unable to get out of their sleeping bags without help. Dizziness was the most common symptom within the first two weeks and was reported in 92% of cases and 13% of controls, followed by headache (87% and 39%) and weakness (76% and 26%). Most symptoms were already present in the first hour, but vomiting, chest pain, and hearing disorders typically had a delayed onset. Headaches, cognitive impairment, and impaired vision were the slowest to resolve. After an initial maximum of 5.6 +/- 2.9 symptoms (p <0.0001 for the comparison with controls), cases reported 5.2 +/- 2.5 symptoms at two days, 1.9 +/- 2.3 symptoms at two weeks, and 1.3 +/-1.6 symptoms at one year (p <0.0001 for decrease over time). Initial palpitations (p = 0.002) and visual changes (p = 0.0003) were independent predictors of a higher symptom score at one year. INTERPRETATION:In acute CO poisoning there are immediate and delayed symptoms suggesting different pathogenic mechanisms. Visual changes and palpitations are independent predictors of residual symptoms at one year.
journal_name
Swiss Med Wklyjournal_title
Swiss medical weeklyauthors
Henz S,Maeder Mdoi
2005/27/smw-11149keywords:
subject
Has Abstractpub_date
2005-07-09 00:00:00pages
398-408issue
27-28eissn
1424-7860issn
1424-3997pii
smw-11149journal_volume
135pub_type
杂志文章abstract::Current guidelines from the Swiss Association against Osteoporosis (SVGO) dating from 2015 recommend therapy for men and women at increased fracture risk, specifically those with a vertebral or hip fracture; those with bone mineral density T-score <−2.5 at spine or hip; and those with a high 10-year probability ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2020.20352
更新日期:2020-09-29 00:00:00
abstract::This article discusses communication challenges in end-of-life decision making and outlines strategies from an area of growing interest and research. ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2020.20351
更新日期:2020-09-18 00:00:00
abstract::The ex utero intrapartum treatment (EXIT) procedure is designed to guarantee sufficient oxygenation for a foetus at risk of airway obstruction. This is achieved by improving lung ventilation, usually by establishing an airway during caesarean delivery whilst preserving the foetal-placental circulation temporarily. Ind...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:2007/19/smw-11526
更新日期:2007-05-19 00:00:00
abstract::We report on two toddlers suffering from Mycobacterium bohemicum lymphadenitis. Acid-fast bacilli were cultured from submandibular lymph nodes and identified by molecular methods as Mycobacterium bohemicum. Surgical treatment was successful and complemented by oral treatment with clarithromycin and rifampicin. ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2004/15/smw-10558
更新日期:2004-04-17 00:00:00
abstract:PRINCIPLES:Heart failure is associated with a grim prognosis. Disease management programmes can improve prognosis in heart failure patients but the applicability to the general population remains limited. We aimed to compare the outcome, pharmacological therapy, and quality of life in unselected heart failure patients ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2006/17/smw-11274
更新日期:2006-04-29 00:00:00
abstract:BACKGROUND:Glomerulonephritis is a rare yet serious group of diseases with a high risk of progression to end-stage renal disease. For optimal healthcare planning, detailed epidemiological and demographic data are essential. Despite their clinical relevance, these data are largely lacking in Switzerland. OBJECTIVE:The ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2020.20353
更新日期:2020-10-06 00:00:00
abstract:STUDY/PRINCIPLES:Physical activity improves the clinical course of the metabolic syndrome and its risk factors. The aim of this study was to investigate the physical activity behaviour in patients with metabolic syndrome in regard to the recommendation of the Federal Offices of Public Health (BAG) and Sports (BASPO): "...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2012.13691
更新日期:2012-10-25 00:00:00
abstract:BACKGROUND:The Swiss Monitoring of Potential Organ Donors (SwissPOD) was initiated to investigate the causes of the overall low organ donation rate in Switzerland. The objective of our study was an assessment of the donation after brain death (DBD) process in Swiss adult intensive care units (ICUs), and to provide an o...
journal_title:Swiss medical weekly
pub_type: 杂志文章,多中心研究
doi:10.4414/smw.2014.14045
更新日期:2014-10-23 00:00:00
abstract:BACKGROUND:The pathogenesis of elevated blood pressure and other cardiovascular risk factors in the population and their progression over time is still incompletely understood, especially in young and healthy adults. METHODS:The genetic and phenotypic determinants of blood pressure and other cardiovascular risk factor...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2013.13728
更新日期:2013-01-08 00:00:00
abstract::Antiosteoporotic drugs are recommended in patients with fragility fractures and in patients considered to be at high fracture risk on the basis of clinical risk factors and/or low bone mineral density. As first-line treatment most patients are started with an antiresorptive treatment, i.e. drugs that inhibit osteoclas...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2017.14484
更新日期:2017-08-16 00:00:00
abstract:BACKGROUND:The principality of Liechtenstein had its first COVID-19 case at the beginning of March 2020. After exponential growth, the pandemic’s first wave was contained, with the last case being diagnosed 52 days after the initial occurrence. AIM:To characterise the COVID-19 pandemic in Liechtenstein. METHODS...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2020.20361
更新日期:2020-10-16 00:00:00
abstract:PURPOSE:There is increasing pressure on general practitioners (GPs) to identify patients with abdominal obesity in order to reduce the life-threatening consequences of this condition in the population. We aimed to confirm previous findings on the inaccuracy of anthropometric measurements performed by GPs in an academic...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2015.14115
更新日期:2015-02-21 00:00:00
abstract:AIM OF THE STUDY:In Switzerland, screening concepts for the prevention of sports-associated sudden cardiac death are still insufficiently established in the large group of competitive athletes who are not integrated in an Olympic- or other high-level squad. The aim of the present study was to objectively determine the ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2012.13575
更新日期:2012-05-31 00:00:00
abstract:BACKGROUND:Considerable criticism has lately been raised by the media regarding the quality of Swiss medical expertises. The present investigation was therefore undertaken to assess the professional quality of Swiss medical expertises. The study was part of a market analysis of medical expertises (MGS study). METHODS:...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2011.13173
更新日期:2011-03-04 00:00:00
abstract:OBJECTIVES:Body temperature (BT) was shown to have impact on outcome in several medical conditions. This study investigated the prognostic impact of BT in patients with acute heart failure (HF). DESIGN AND PATIENTS:The B-type natriuretic peptide for Acute Shortness of breath EvaLuation (BASEL) study prospectively enro...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2008/21/smw-12013
更新日期:2008-05-31 00:00:00
abstract::The atherogenic lipoprotein phenotype is characterised by a moderate increase in plasma triglycerides, a decrease in high density lipoprotein cholesterol and the prevalence of smaller denser low density lipoprotein particles. The prevalence of this partially inheritable phenotype is approximately 30% and is a feature ...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:2004/49/smw-10813
更新日期:2004-12-18 00:00:00
abstract:BACKGROUND:Organs donated for transplantation remain a scarce resource in Switzerland. One of the reasons for this situation is the high percentage of patients or families who refuse to consent to donation. This study aimed to provide an overview of attitudes towards organ donation among Swiss residents, including any ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2017.14401
更新日期:2017-02-03 00:00:00
abstract:OBJECTIVES:Several studies have reported prolonged QTc intervals in patients under methadone maintenance treatment, including development of torsade-de-pointes arrhythmia and death. It is still not clear why some patients develop critical QTc extensions while others do not. METHODS:ECG findings in a convenience sample...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2013.13852
更新日期:2013-09-06 00:00:00
abstract:INTRODUCTION:Graft rejection and infection remain major morbidities following orthotopic liver transplantation (OLT). Rejection treatment may be associated with an increased rate of infectious complications. The aim of this study was to determine the relationship between rejection, rejection therapy and the risk of ass...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2005/39/smw-10399
更新日期:2005-10-01 00:00:00
abstract::Coronary microcirculation plays a crucial role for the outcomes of patients with STEMI. Although PPCI improves outcomes compared to thrombolysis, a substantial amount of STEMI patients do not achieve optimal myocardial reperfusion. Angiographic methods for assessment of reperfusion like TIMI Flow and MBG are easy to u...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:10.4414/smw.2011.13313
更新日期:2011-12-09 00:00:00
abstract:QUESTION UNDER STUDY:To assess clinical reactions, immune responses and adverse events to undiluted, three- and sixfold diluted Lister strain vaccine stockpiled in Switzerland. METHODS:A prospective, triple-blinded, randomised, parallel group clinical trial was performed. RESULTS:From 2001 to 2007 104 persons with an...
journal_title:Swiss medical weekly
pub_type: 杂志文章,随机对照试验
doi:2008/27/smw-11966
更新日期:2008-07-12 00:00:00
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journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2016.14305
更新日期:2016-05-31 00:00:00
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journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2019.20050
更新日期:2019-04-04 00:00:00
abstract:QUESTIONS UNDER STUDY:Some evidence suggests that a loud voice is a core characteristic of medical professionals. It is unknown whether medical students talk louder than their non-medical peers and, if so, whether they commence their studies with a loud voice, representing a characteristic of admission, or whether soun...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2012.13534
更新日期:2012-03-09 00:00:00
abstract::Since 1946 the development of fractionation and purification methods of human plasma led to biologic immunoglobulin for intravenous use (IVIG). In 1980 a child with refractory immune thrombocytopenia (ITP), bleeding and secondary hypogammaglobulinaemia due to long term immunosuppressive treatment got IVIG. His platele...
journal_title:Swiss medical weekly
pub_type: 历史文章,杂志文章,评审
doi:10.4414/smw.2012.13593
更新日期:2012-05-31 00:00:00
abstract::We report a case series of 11 patients with severe E. faecium infections treated with daptomycin. All strains were resistant to ampicillin (MIC >8 mg/l), but susceptible to vancomycin. Seven out of 11 strains were also highly resistant to gentamicin (MIC >500 mg/l). All patients were treated with multiple broad-spectr...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2012.13603
更新日期:2012-06-26 00:00:00
abstract:BACKGROUND:The transition from undergraduate to postgraduate training is a crucial career step for physicians. Several international studies have shown that graduates feel insufficiently prepared to perform various aspects of clinical practice. The publication of a national framework for undergraduate medical education...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2020.20370
更新日期:2020-11-24 00:00:00
abstract::Sequencing the human genome was the big challenge of the last decade. Ten years later, the large amount of DNA sequences accumulated in our databases allows us to look at genome variations between humans. The level of complexity of these variations is much higher than previously expected. It goes from changes in the n...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:10.4414/smw.2011.13321
更新日期:2011-12-19 00:00:00
abstract::Dementia with Lewy bodies (DLB) accounts for 15-20% of all autopsy confirmed dementias in old age. Characteristic histopathological changes are intracellular Lewy bodies and Lewy neurites, with abundant senile plaques but sparse neurofibrillary tangles. Core clinical features are fluctuating cognitive impairment, pers...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:2003/09/smw-10028
更新日期:2003-03-08 00:00:00
abstract:PRINCIPLES:Small dense LDLs have been found to be associated with type 2 diabetes (T2DM). This association has been observed in the context of decreased HDL cholesterol and increased triglycerides. METHODS:In the present study the relationship between LDL particle size and insulin sensitivity was assessed in 46 patien...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2008/19/smw-12124
更新日期:2008-05-03 00:00:00