Procalcitonin: how a hormone became a marker and mediator of sepsis.

Abstract:

:Calcitonin was discovered in the early 1960s [1], at which time it was assumed to be a single hormone with a yet-to-be-determined role in human physiology. Since then it has been found to be only one entity among a large array of related circulating peptides, at least one of which has a pivotal role in the host response to microbial infections [2, 3]. The aim of this review is to describe this metamorphosis of an endocrine hormone to a new class of hormokine mediators in infectious diseases.

journal_name

Swiss Med Wkly

journal_title

Swiss medical weekly

authors

Müller B,Becker KL

doi

2001/41/smw-09751

keywords:

subject

Has Abstract

pub_date

2001-10-20 00:00:00

pages

595-602

issue

41-42

eissn

1424-7860

issn

1424-3997

journal_volume

131

pub_type

杂志文章,评审
  • Diffuse large B-cell lymphoma chemotherapy reveals a combined immunodeficiency syndrome in cartilage hair hypoplasia.

    abstract::Cartilage hair hypoplasia (CHH) is a rare autosomal recessive ribosomopathy characterised by skeletal and integumentary system manifestations. It may also present with varied forms and intensities of haematopoietic and/or immune disorders. We report a 27-year-old female who presented a picture of combined immunodefici...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2018.14606

    authors: Nguyen A,Martin Silva N,de Boysson H,Damaj G,Aouba A

    更新日期:2018-04-24 00:00:00

  • Can geriatric approaches support the care of old patients in emergency departments? A review from a Swiss ED.

    abstract::In the coming decades, old patients will account for an increasing proportion of emergency department (ED) visits. During or after their stay in the ED, they more frequently suffer adverse outcomes than younger patients. There is evidence that specific age-centred approaches improve the outcomes. We therefore reviewed...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:10.4414/smw.2014.14040

    authors: Schoenenberger AW,Exadaktylos AK

    更新日期:2014-12-04 00:00:00

  • Bosentan therapy for chronic thromboembolic pulmonary hypertension. A national open label study assessing the effect of Bosentan on haemodynamics, exercise capacity, quality of life, safety and tolerability in patients with chronic thromboembolic pulmonar

    abstract:STUDY OBJECTIVES:we performed an open-label national study to evaluate the effects of Bosentan on haemodynamics, exercise capacity, quality of life, safety and tolerability in patients with chronic thromboembolic pulmonary hypertension (CTEPH). PATIENTS AND METHODS:fifteen patients with CTEPH not eligible or waiting f...

    journal_title:Swiss medical weekly

    pub_type: 临床试验,杂志文章

    doi:2007/41/smw-11819

    authors: Ulrich S,Speich R,Domenighetti G,Geiser T,Aubert JD,Rochat T,Huber L,Treder U,Fischler M

    更新日期:2007-10-20 00:00:00

  • Education, employment and marriage in long-term survivors of teenage and young adult cancer compared with healthy controls.

    abstract:QUESTIONS UNDER STUDY:Teenage and young adult (TYA) cancer patients are faced with the diagnosis during a challenging period of psychosocial development that may affect social outcomes in the long term. Therefore, we aimed to: (1) determine differences in social outcomes between long-term TYA cancer survivors and healt...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2017.14419

    authors: Mader L,Vetsch J,Christen S,Baenziger J,Roser K,Dehler S,Michel G

    更新日期:2017-03-07 00:00:00

  • Organic dust exposure in dairy farmers in an alpine region.

    abstract:OBJECTIVES:Epidemological studies suggest that farmers are at an increased risk for chronic obstructive pulmonary disease because of exposure to organic dust. We assessed the proportion of farmers among patients with end stage lung disease and we measured the seasonal exposure of dairy farmers to organic dust in a rura...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:2002/13/smw-09892

    authors: Cathomas RL,Brüesch H,Fehr R,Reinhart WH,Kuhn M

    更新日期:2002-04-06 00:00:00

  • Severe injection site reactions after subcutaneous administration of Sayana©.

    abstract:PURPOSE:Sayana® was introduced as the first depot medroxyprogesterone acetate-containing contraceptive that is administered via subcutaneous injection. Within 10 months, the Regional Pharmacovigilance Centre (RPVC) Zurich received several anonymous reports of serious local reactions after Sayana® administration. In thi...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2017.14432

    authors: Jödicke AM,Dahmke H,Damke B,Schäublin M,Kullak-Ublick GA,Weiler S

    更新日期:2017-05-10 00:00:00

  • A report of ten patients with thyroid hemiagenesis: ultrasound screening in patients with thyroid disease.

    abstract:BACKGROUND:Thyroid hemiagenesis (TH) is a rare congenital abnormality of the thyroid gland, characterised by the absence of one lobe. The true prevalence of this congenital abnormality is not known because the absence of one thyroid lobe usually does not cause clinical symptoms by itself. This study aims to identify th...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:smw-12956

    authors: Berker D,Ozuguz U,Isik S,Aydin Y,Ates Tutuncu Y,Akbaba G,Guler S

    更新日期:2010-02-20 00:00:00

  • Intensive care without walls - introduction of a Medical Emergency Team system in a Swiss tertiary care centre.

    abstract:QUESTIONS UNDER STUDY:To improve the response of deteriorating patients during their hospital stay, the University Hospital Bern has introduced a Medical Emergency Team (MET). Aim of this retrospective cohort study is to review the preceding factors, patient characteristics, process parameters and their correlation to ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2014.14027

    authors: Etter R,Takala J,Merz TM

    更新日期:2014-10-08 00:00:00

  • Is a change in vocal loudness a first step towards becoming a medical doctor?

    abstract:QUESTIONS UNDER STUDY:Some evidence suggests that a loud voice is a core characteristic of medical professionals. It is unknown whether medical students talk louder than their non-medical peers and, if so, whether they commence their studies with a loud voice, representing a characteristic of admission, or whether soun...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2012.13534

    authors: Kiese-Himmel C,Himmel W,Rodenstock M,Scherer M

    更新日期:2012-03-09 00:00:00

  • Innovative transition interventions to better align healthcare needs in hospitalised medical patients.

    abstract::Understanding how best to manage the complex healthcare needs of hospitalised, mostly multimorbid medical patients is an international priority. Healthcare should be effective, safe and provide high quality at a reasonable cost. However, basic logistic and organisational issues of medical ward-based care have received...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2017.14515

    authors: Kutz A,Ebrahimi F,Struja T,Greenwald J,Schuetz P,Mueller B

    更新日期:2017-10-22 00:00:00

  • Bosentan for patients with steroid-resistant pulmonary sarcoidosis: a randomised controlled trial.

    abstract:BACKGROUND:Sarcoidosis is a disorder of unknown aetiology. Most patients have steroid-responsive disease, but side effects and steroid resistance may necessitate alternative treatments. Endothelin has in-vitro fibrogenic activity and the endothelin system is activated in sarcoidosis. OBJECTIVES:We studied the efficacy...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,随机对照试验

    doi:10.4414/smw.2018.14677

    authors: Hostettler K,Baty F,Kleiner R,Junker L,Tamm M,Brutsche M

    更新日期:2018-10-28 00:00:00

  • Kerley B lines in the lung apex - a distinct CT sign for pulmonary congestion.

    abstract:AIMS OF THE STUDY:The purpose of this study was to establish a new computed tomography (CT) sign for pulmonary congestion (Kerley B lines in the lung apex in patients with cardiac or renal insufficiency) and to find the best signs to differentiate between pulmonary congestion and interstitial lung disease (ILD). METHO...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2019.20119

    authors: Loebelenz LI,Ebner L,Obmann VC,Huber AT,Christe A

    更新日期:2019-09-02 00:00:00

  • Diagnosis of mild bleeding disorders.

    abstract::The precise diagnosis of a severe haemorrhagic disorder is usually not too problematic. However, physicians are most often faced with individuals consulting for mild haemorrhagic symptoms, particularly occurring after a surgical intervention. The problem here is to evaluate whether this person really has a bleeding di...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:smw-12476

    authors: de Moerloose P,Levrat E,Fontana P,Boehlen F

    更新日期:2009-06-13 00:00:00

  • General practitioner's adherence to the COPD GOLD guidelines: baseline data of the Swiss COPD Cohort Study.

    abstract::PRINCIPLES: Chronic obstructive pulmonary disease (COPD) is a major burden on patients and healthcare systems. Diagnosis and the management of COPD are often administered by general practitioners (GPs). This analysis investigated the adherence of GPs in Switzerland to the Global Initiative for Chronic Obstructive Lung...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2010.13053

    authors: Jochmann A,Neubauer F,Miedinger D,Schafroth S,Tamm M,Leuppi JD

    更新日期:2010-08-09 00:00:00

  • Evaluation of prenatal diagnosis of congenital heart disease in a regional controlled case study.

    abstract:AIMS:This study evaluated the evolution of the prenatal diagnosis of congenital heart disease (CHD) between 2003 and 2008 and its repercussion for the CHD prevalence rate at birth in a well-defined population (Canton of Vaud, Switzerland). METHODS AND RESULTS:All 572 cases of CHD reported in the Eurocat Registry of Va...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2014.14068

    authors: Rossier MC,Mivelaz Y,Addor MC,Sekarski N,Meijboom EJ,Vial Y

    更新日期:2014-12-04 00:00:00

  • Accuracy of doctors' anthropometric measurements in general practice.

    abstract:PURPOSE:There is increasing pressure on general practitioners (GPs) to identify patients with abdominal obesity in order to reduce the life-threatening consequences of this condition in the population. We aimed to confirm previous findings on the inaccuracy of anthropometric measurements performed by GPs in an academic...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2015.14115

    authors: Sebo P,Haller D,Pechère-Bertschi A,Bovier P,Herrmann F

    更新日期:2015-02-21 00:00:00

  • Gestational age-adapted oxygen saturation targeting and outcome of extremely low gestational age neonates (ELGANs).

    abstract:QUESTIONS UNDER STUDY:Optimal oxygen saturation (SpO2) targets for extremely low gestational age neonates (ELGANs, gestational age [GA] <28 weeks) are unknown. Conflicting results from five recently published multicentre trials, which randomised ELGANs to high (91 to 95%) or low (85 to 89%) SpO2 targets from birth up t...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2015.14197

    authors: Hergenhan A,Steurer M,Berger TM

    更新日期:2015-11-02 00:00:00

  • Financial incentives to improve organ donation: what is the opinion of the Vaud French-speaking population?

    abstract:BACKGROUND:With the increase of the organ shortage, several authors assume that financial incentives would improve organ donation rates and fill the unbalance between the demand and the organs available for transplant medicine. This line of argument has been criticised with people arguing that an exchange of money for ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2011.13312

    authors: Bosisio F,Santiago M,Benaroyo L

    更新日期:2011-12-09 00:00:00

  • Comparison of the safety and effectiveness of endoscopic biliary decompression by nasobiliary catheter and plastic stent placement in acute obstructive cholangitis.

    abstract:BACKGROUND:Endoscopic retrograde biliary drainage (ERBD) using a plastic stent is suggested to be as effective as endoscopic nasobiliary drainage (ENBD) with a nasobiliary catheter for temporary biliary drainage in acute obstructive cholangitis. However, there are few studies that have compared the two methods. We ther...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,随机对照试验

    doi:10.4414/smw.2013.13823

    authors: Zhang RL,Cheng L,Cai XB,Zhao H,Zhu F,Wan XJ

    更新日期:2013-07-07 00:00:00

  • Cost of disorders of the brain in Switzerland with a focus on mental disorders.

    abstract:QUESTIONS UNDER STUDY:This study aims at estimating the costs of disorders of the brain in Switzerland based on the published epidemiological and economic evidence. METHODS:the data presented for Switzerland are derived from the "cost of disorders of the brain in Europe" study of the European Brain Counsil (EBC). Avai...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:2008/01/smw-11910

    authors: Jäger M,Sobocki P,Rössler W

    更新日期:2008-01-12 00:00:00

  • Current prevalence of self-reported interpersonal violence among adult patients seen at a university hospital emergency department in Switzerland.

    abstract:OBJECTIVE:To evaluate the current prevalence of self-reported interpersonal violence amongst patients consulting at the emergency department (ED) of a university hospital and to describe the characteristics of the violence sustained. METHODS:Ours was a cross-sectional study using a modified version of the Partner Viol...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2019.20147

    authors: Douet T,Ohl A,Hügli O,Romain-Glassey N,Carron PN

    更新日期:2019-12-17 00:00:00

  • Improvement in function after spinal cord injury: the black-box entitled rehabilitation.

    abstract::Rehabilitation can be referred to as a "black box" because little is known about what specific interventions comprise the rehabilitation process, including patients with spinal cord injury (SCI). Despite that rehabilitation professionals can "see" daily what rehabilitation looks like, the contribution of each interven...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:10.4414/smw.2012.13673

    authors: van Hedel HJ

    更新日期:2012-09-20 00:00:00

  • Identification of a MAFB mutation in a patient with multicentric carpotarsal osteolysis.

    abstract::Multicentric carpotarsal osteolysis (MCTO) is an autosomal dominant disease of the skeleton characterised by progressive destruction of carpal and tarsal bones. Recently, it has been demonstrated that this disease is caused by heterozygous mutations in the gene for the transcriptional repressor MAFB. We analysed genom...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2017.14529

    authors: Zhuang L,Adler S,Aeberli D,Villiger PM,Trueb B

    更新日期:2017-10-27 00:00:00

  • Patients' understanding of blood tests and attitudes to HIV screening in the emergency department of a Swiss teaching hospital: a cross-sectional observational study.

    abstract:BACKGROUND:In Switzerland, patients may undergo "blood tests" without being informed what these are screening for. Inadequate doctor-patient communication may result in patient misunderstanding. We examined what patients in the emergency department (ED) believed they had been screened for and explored their attitudes t...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2015.14206

    authors: Favre-Bulle T,Baudat D,Darling KE,Mamin R,Peters S,Cavassini M,Hugli O

    更新日期:2015-12-04 00:00:00

  • Management of hepatitis C in opioid agonist therapy patients of the Swiss canton Aargau within and outside the cohort study.

    abstract::With regard to HCV elimination in opioid agonist therapy patients by 2030, case finding and regular screening for new and re-infections remain a challenge, especially for non-cohort patients in a decentralised setting. Documentation of the HCV sero- and RNA status of each opioid agonist therapy  patient by the ca...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2020.20317

    authors: Schürch S,Fux CA,Dehler S,Conen A,Knuchel J,Friedl A,Eigenmann F,Roser P,Ackle P,Bregenzer A

    更新日期:2020-08-06 00:00:00

  • Oscillometric measurement of ankle-brachial index in patients with suspected peripheral disease: comparison with Doppler method.

    abstract:QUESTION UNDER STUDY:Purpose was to validate accuracy and reliability of automated oscillometric ankle-brachial (ABI) measurement prospectively against the current gold standard of Doppler-assisted ABI determination. METHODS:Oscillometric ABI was measured in 50 consecutive patients with peripheral arterial disease (n ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:smw-12636

    authors: Diehm N,Dick F,Czuprin C,Lawall H,Baumgartner I,Diehm C

    更新日期:2009-06-27 00:00:00

  • Aortic distensibility alterations in adults with m.3243A>G MELAS gene mutation.

    abstract:PRINCIPLES:MELAS, or mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes is a new distinctive clinical entity. The current study was designed to assess ascending aortic elasticity in adult patients with MELAS syndrome and in gene carriers, and to compare the results with age- and gender-mat...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:smw-12390

    authors: Nemes A,Geleijnse ML,Sluiter W,Vydt TC,Soliman OI,van Dalen BM,Vletter WB,ten Cate FJ,Smeets HJ,de Coo RF

    更新日期:2009-02-21 00:00:00

  • Tolerance to celecoxib in patients with a history of adverse reactions to nonsteroidal anti-inflammatory drugs.

    abstract:BACKGROUND:Adverse reactions to nonsteroidal antiinflammatory drugs (NSAIDs) are frequently reported, particularly among asthmatic patients. To date, there is no causal treatment available apart from tolerance induction. Therefore, the search for safe alternative drugs is of pivotal importance in clinical practice. OB...

    journal_title:Swiss medical weekly

    pub_type: 临床试验,杂志文章

    doi:2006/43/smw-11358

    authors: Roll A,Wüthrich B,Schmid-Grendelmeier P,Hofbauer G,Ballmer-Weber BK

    更新日期:2006-10-28 00:00:00

  • Illuminating human health through cell mechanics.

    abstract::Cells reside in mechanically rich and dynamic microenvironments, and the complex interplay between mechanics and biology is widely acknowledged. Recent research has yielded insights linking the mechanobiology of cells, human physiology, and pathophysiology. In particular, we have learned of the cell's astounding abili...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:10.4414/smw.2013.13766

    authors: Steward RL Jr,Rosner SR,Zhou EH,Fredberg JJ

    更新日期:2013-03-14 00:00:00

  • Arrhythmias in patients with surgically treated atrial septal defects.

    abstract::Atrial arrhythmias complicate the clinical course of adult patients with an atrial septal defect. Atrial flutter is more prevalent in younger patients, and frequently regresses after surgical defect closure. Atrial fibrillation however, which results from a chronic underlying disease, rarely reverts to sinus rhythm af...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:2005/11/smw-10926

    authors: Berger F,Vogel M,Kretschmar O,Dave H,Prêtre R,Dodge-Khatami A

    更新日期:2005-03-19 00:00:00