Abstract:
OBJECTIVE:The methods used to diagnose and classify ovarian cancer have changed over the past decade. We used hospital registry data to assess the incidence, treatment durations and hospital costs of ovarian cancer in Switzerland. METHODS:We carried out a retrospective analysis of a hospital registry covering all inpatient care episodes in Switzerland between 1998 and 2012. Ovarian cancer incidence was assessed by identifying patients with a first ovarian cancer diagnosis as the main reason for hospital stay after an event-free period. We assessed the duration and cost of ovarian cancer treatment sequences as well as the evolution of hospital patient volume over time. RESULTS:The average age-adjusted incidence rate was 14.6 per 100,000 women per year between 2004 and 2012. This rate is substantially higher (+35.5%) than the corresponding rate published by the National Institute for Cancer Epidemiology and Registration (NICER). Hospital patient volume was low in most cases, with more than 40% of patients treated in hospitals with fewer than 20 cases per year. However, the share of patients treated in hospitals with more than 30 cases per year has increased substantially since 2009. CONCLUSIONS:We found a substantial difference between the ovarian cancer incidence estimate based on hospital registry data and the corresponding estimate by NICER. The reasons for this substantial difference should be carefully explored. A case-wise comparison could determine whether the difference is due to over- or under-reporting in one of the two registries. The low ovarian cancer patient volume in many hospitals is in conflict with the numbers required for certified specialised cancer centres. The recent increase in patient volume in specialised cancer centres, however, might reflect a growing understanding of the needs and requirements of comprehensive cancer care.
journal_name
Swiss Med Wklyjournal_title
Swiss medical weeklyauthors
Wieser S,Schmidt M,Kind AB,Heinzelmann-Schwarz VAdoi
10.4414/smw.2018.14647subject
Has Abstractpub_date
2018-07-29 00:00:00pages
w14647eissn
1424-7860issn
1424-3997pii
Swiss Med Wkly. 2018;148:w14647journal_volume
148pub_type
杂志文章abstract:BACKGROUND:Neuroendocrine neoplasms (NENs) are difficult to diagnose. We used SwissNET data to characterise NEN patients followed in the two academic centres of western Switzerland (WS), and to compare them with patients followed in eastern Switzerland (ES) as well as with international guidelines. METHOD:SwissNET is ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2014.13924
更新日期:2014-02-19 00:00:00
abstract:OBJECTIVE:To examine the demographics, evolution and outcome of patients suffering from malignancies admitted to a medical intensive care unit. PATIENTS AND METHODS:Single centre retrospective cohort study of patients with malignancies. Data on demographics, diagnosis laboratory tests, provided therapy and outcome wer...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2013.13741
更新日期:2013-03-26 00:00:00
abstract:BACKGROUND:The Swiss Monitoring of Potential Organ Donors (SwissPOD) was initiated to investigate the causes of the overall low organ donation rate in Switzerland. The objective of our study was an assessment of the donation after brain death (DBD) process in Swiss adult intensive care units (ICUs), and to provide an o...
journal_title:Swiss medical weekly
pub_type: 杂志文章,多中心研究
doi:10.4414/smw.2014.14045
更新日期:2014-10-23 00:00:00
abstract:OBJECTIVE:Regular checking of the fitness to drive of elderly car-license holders is required in some countries, and this will become increasingly important as more countries face aging populations. The present study investigated whether the analysis of saccadic eye movements could be used as a screening method for the...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2015.14098
更新日期:2015-02-09 00:00:00
abstract:BACKGROUND:Although airway obstruction, as defined by improvement of forced expiratory volume in one second (FEV1) and/or forced vital capacity (FVC), is irreversible in patients with COPD, they clearly seem to benefit from treatment with inhaled bronchodilators. AIMS:To assess the response pattern of residual volume ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2008/17/smw-11992
更新日期:2008-05-03 00:00:00
abstract::Lung transplantation has now been performed for more than 30 years in patients with end-stage chronic obstructive pulmonary disease (COPD). This disease is the major indication for lung transplantation, involving more than one third of the procedures worldwide. Although lung transplantation in COPD patients has clearl...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:smw-12377
更新日期:2009-01-10 00:00:00
abstract:: ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2011.13166
更新日期:2011-03-18 00:00:00
abstract:BACKGROUND:since 1999 data from pulmonary hypertension (PH) patients from all PH centres in Switzerland were prospectively collected. We analyse the epidemiological aspects of these data. METHODS:PH was defined as a mean pulmonary artery pressure of >25 mm Hg at rest or >30 mm Hg during exercise. Patients with pulmona...
journal_title:Swiss medical weekly
pub_type: 杂志文章,多中心研究
doi:2008/25/smw-11915
更新日期:2008-06-28 00:00:00
abstract::Advance directives emerged in the 1960s with the goal of empowering people to exert control over their future medical decisions. However, it has become apparent, over recent years, that advance directives do not sufficiently capture the temporal and relational aspects of planning treatment and care. Advance care plann...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:10.4414/smw.2018.14706
更新日期:2018-12-30 00:00:00
abstract:AIMS OF THE STUDY:Premature discontinuation occurs in about 25% of randomised clinical trials in Switzerland; it mainly affects investigator-initiated trials and is mostly due to problems with recruitment of patients. The aim of this study was to qualitatively investigate reasons for trial discontinuation due to poor p...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2017.14556
更新日期:2017-11-16 00:00:00
abstract:INTRODUCTION:Graft rejection and infection remain major morbidities following orthotopic liver transplantation (OLT). Rejection treatment may be associated with an increased rate of infectious complications. The aim of this study was to determine the relationship between rejection, rejection therapy and the risk of ass...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2005/39/smw-10399
更新日期:2005-10-01 00:00:00
abstract::Congenital tuberculosis was first suspected in a premature infant with patent ductus arteriosus (PDA), progressive respiratory distress and septic shock, when an enlarged mediastinal lymph node was noted intraoperatively at the time of PDA ligature. Culture revealed Mycobacterium tuberculosis. The asymptomatic mother ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2002/41/smw-10101
更新日期:2002-11-23 00:00:00
abstract:INTRODUCTION:In general practice, the diagnosis of dementia is often delayed. Therefore, the Swiss National Dementia Strategy 2014 concluded that action was needed to improve patient care. Little is known about GPs’ confidence in and approach to the diagnosis, disclosure and post-diagnostic management of individu...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2018.14695
更新日期:2018-12-21 00:00:00
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journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2017.14401
更新日期:2017-02-03 00:00:00
abstract:QUESTIONS UNDER STUDY:In view of the alarming trend in childhood obesity (O) and overweight (OW) observed in certain countries, the aim of the study is to measure the prevalence of O and OW in successive cohorts of elementary school children in Geneva. METHODS:All 5-6-year-old children attending public schools in the ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2010.13040
更新日期:2010-07-22 00:00:00
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journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2020.20204
更新日期:2020-04-15 00:00:00
abstract:INTRODUCTION:Selection of medical students varies between German- and French-speaking Swiss faculties. Geneva introduced an aptitude test in 2010, aimed at helping decision making among students. The test was compulsory: it had to be taken by those who intended to register for medical studies. But it was not selective:...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2013.13872
更新日期:2013-09-19 00:00:00
abstract::Cartilage hair hypoplasia (CHH) is a rare autosomal recessive ribosomopathy characterised by skeletal and integumentary system manifestations. It may also present with varied forms and intensities of haematopoietic and/or immune disorders. We report a 27-year-old female who presented a picture of combined immunodefici...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2018.14606
更新日期:2018-04-24 00:00:00
abstract::With regard to HCV elimination in opioid agonist therapy patients by 2030, case finding and regular screening for new and re-infections remain a challenge, especially for non-cohort patients in a decentralised setting. Documentation of the HCV sero- and RNA status of each opioid agonist therapy patient by the ca...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2020.20317
更新日期:2020-08-06 00:00:00
abstract::Coronavirus disease 2019 (COVID-19) is primarily a pulmonary disease, but also affects the cardiovascular system in multiple ways. In this review, we will summarise and put into perspective findings and debates relating to the diverse aspects of cardiovascular involvement of COVID-19. We will review evidence for the r...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:10.4414/smw.2020.20417
更新日期:2020-12-31 00:00:00
abstract:BACKGROUND:Many antimicrobial stewardship programmes (ASPs) target the intensive care unit owing to high antimicrobial utilisation. In this review, we summarise and assess the quality of evidence supporting the implementation of various ASP strategies in the intensive care unit setting with a focus on publications betw...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:10.4414/smw.2015.14220
更新日期:2015-12-21 00:00:00
abstract:QUESTIONS UNDER STUDY:Monitoring of antimicrobial resistance is a key component of antibiotic stewardship programs. In 2007, a significantly higher resistance rate of Escherichia coli to ciprofloxacin was found at the Department of Urology, University Hospital Zurich, Switzerland, when compared to other hospital units....
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2010.13059
更新日期:2010-07-15 00:00:00
abstract:QUESTIONS UNDER STUDY:Optimal oxygen saturation (SpO2) targets for extremely low gestational age neonates (ELGANs, gestational age [GA] <28 weeks) are unknown. Conflicting results from five recently published multicentre trials, which randomised ELGANs to high (91 to 95%) or low (85 to 89%) SpO2 targets from birth up t...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2015.14197
更新日期:2015-11-02 00:00:00
abstract:PRINCIPLES:We aimed to evaluate the efficacy of, and treatment satisfaction with, insulin glargine administered with SoloSTAR® or ClikSTAR® pens in patients with type 2 diabetes mellitus managed by primary care physicians in Switzerland. METHODS:A total of 327 patients with inadequately controlled type 2 diabetes were...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2015.14114
更新日期:2015-03-05 00:00:00
abstract:BACKGROUND:Endoscopic retrograde biliary drainage (ERBD) using a plastic stent is suggested to be as effective as endoscopic nasobiliary drainage (ENBD) with a nasobiliary catheter for temporary biliary drainage in acute obstructive cholangitis. However, there are few studies that have compared the two methods. We ther...
journal_title:Swiss medical weekly
pub_type: 杂志文章,随机对照试验
doi:10.4414/smw.2013.13823
更新日期:2013-07-07 00:00:00
abstract:BACKGROUND:The transition from undergraduate to postgraduate training is a crucial career step for physicians. Several international studies have shown that graduates feel insufficiently prepared to perform various aspects of clinical practice. The publication of a national framework for undergraduate medical education...
journal_title:Swiss medical weekly
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doi:10.4414/smw.2020.20370
更新日期:2020-11-24 00:00:00
abstract::Our senses are the main information channels through which we perceive and interact with the world. Consequently, the physical and social functioning of patients suffering from severe sensory disabilities is limited on several levels. This has motivated the development of a novel therapeutic alternative: “artifi...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:10.4414/smw.2019.20061
更新日期:2019-06-02 00:00:00
abstract::With reference to the Year of the Lung, current knowledge of the respiratory effects of current ambient air pollution is reviewed. Acute respiratory effects are well established. Studies such as SAPALDIA and others now shed light on the long-term effects on chronic pathologies and on the health benefit of air quality ...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:10.4414/smw.2010.13129
更新日期:2010-11-18 00:00:00
abstract::Mantle cell lymphoma (MCL) is a relatively rare lymphoma entity accounting for an estimated 3%-6% of all non-Hodgkin's lymphoma cases. Characterised by both the incurability of indolent lymphomas and the rapid growth of aggressive lymphomas, MCL has a median overall survival of only 4-5 years. Although the disease oft...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:10.4414/smw.2013.13868
更新日期:2013-11-13 00:00:00
abstract::Patients with a solid organ transplant have increased in numbers and in individual survival in Switzerland over the last decades. As a consequence of long-term immunosuppression, skin cancer in solid organ recipients (SOTRs) has been recognized as an important problem. Screening and education of potential SOTRs about ...
journal_title:Swiss medical weekly
pub_type: 杂志文章,实务指引
doi:smw-12725
更新日期:2009-07-25 00:00:00