Laser scanning microscopy combined with image restoration to analyse a 3D model of the human epithelial airway barrier.

abstract：:Dementia with Lewy bodies (DLB) accounts for 15-20% of all autopsy confirmed dementias in old age. Characteristic histopathological changes are intracellular Lewy bodies and Lewy neurites, with abundant senile plaques but sparse neurofibrillary tangles. Core clinical features are fluctuating cognitive impairment, pers...

journal_title：Swiss medical weekly

authors： Mosimann UP,McKeith IG

更新日期：2003-03-08 00:00:00

abstract：BACKGROUND:Nasopharyngeal carcinoma is a rare tumor entity in Switzerland. In contrast, it is endemic in Asian and African countries. Retrospective studies have been conducted in order to identify risk factors and prognostic determinants of nasopharyngeal carcinoma. Nonetheless, these trials were mostly conducted in re...

journal_title：Swiss medical weekly

authors： Sidler D,Thum P,Winterhalder R,Huber G,Haerle SK

更新日期：2010-05-01 00:00:00

abstract：:The ex utero intrapartum treatment (EXIT) procedure is designed to guarantee sufficient oxygenation for a foetus at risk of airway obstruction. This is achieved by improving lung ventilation, usually by establishing an airway during caesarean delivery whilst preserving the foetal-placental circulation temporarily. Ind...

journal_title：Swiss medical weekly

authors： Kern C,Ange M,Morales,Peiry B,Pfister RE

更新日期：2007-05-19 00:00:00

abstract：:HMG-CoA reductase inhibitors, or statins, are lipid-lowering agents that have been shown to effectively decrease severe rejection periods and development of transplant coronary artery disease after heart transplantation. Precise regulation of major histocompatibility complex class II (MHC class II) gene expression pla...

journal_title：Swiss medical weekly

authors： Kwak B,Mulhaupt F,Veillard N,Pelli G,Mach F

更新日期：2001-01-27 00:00:00

abstract：QUESTIONS UNDER STUDY:Teenage and young adult (TYA) cancer patients are faced with the diagnosis during a challenging period of psychosocial development that may affect social outcomes in the long term. Therefore, we aimed to: (1) determine differences in social outcomes between long-term TYA cancer survivors and healt...

journal_title：Swiss medical weekly

authors： Mader L,Vetsch J,Christen S,Baenziger J,Roser K,Dehler S,Michel G

更新日期：2017-03-07 00:00:00

abstract：AIMS OF THE STUDY:Healthy adults have had the option to receive prescriptionless vaccination against influenza in pharmacies of several Swiss cantons since the 2015/16 influenza season. We aimed to assess in a cost-benefit analysis the resulting net benefits for the Swiss economy and public health, and the benefits tha...

journal_title：Swiss medical weekly

authors： Brunner I,Schmedders K,Wolfensberger A,Schreiber PW,Kuster SP

更新日期：2019-12-17 00:00:00

abstract：QUESTION UNDER STUDY:What are the trends in avoidable cancer mortality in Switzerland and neighbouring countries? METHODS:Mortality data and population estimates 1996-2010 were obtained from the Swiss Federal Statistical Office for Switzerland and the World Health Organization Mortality Database (http://www.who.int/he...

journal_title：Swiss medical weekly

authors： Feller A,Mark MT,Steiner A,Clough-Gorr KM

更新日期：2015-10-02 00:00:00

abstract：:Osteoporosis is complicated by the occurrence of fragility fractures. Over past years, various treatment options have become available, mostly potent antiresorptive agents such as bisphosphonates and denosumab. However, antiresorptive therapy cannot fully and rapidly restore bone mass and structure that has been lost ...

journal_title：Swiss medical weekly

authors： Meier C,Lamy O,Krieg MA,Mellinghoff HU,Felder M,Ferrari S,Rizzoli R

更新日期：2014-06-04 00:00:00

abstract：BACKGROUND:Hypoxia-inducible factor-1α (HIF-1α) plays an important role in tumour progression and metastasis through activation of many target genes that are especially involved in pivotal aspects of cancer biology. However, the prognostic role of HIF-1α has been controversial in primary patients with lung cancer. This...

journal_title：Swiss medical weekly

authors： Ren W,Mi D,Yang K,Cao N,Tian J,Li Z,Ma B

更新日期：2013-09-06 00:00:00

abstract：QUESTION UNDER STUDY:To evaluate the situation of Female Genital Mutilation (FGM) in Switzerland. METHODS:Through a questionnaire, Swiss gynaecologists were asked if they have been confronted to FGMs, if they have been asked to perform infibulations and FGMs. The health representatives (Kantonsärzte/médecins cantonaux...

journal_title：Swiss medical weekly

authors： Jäger F,Schulze S,Hohlfeld P

更新日期：2002-05-18 00:00:00

abstract：:Over the last few years atypical antipsychotics have been used increasingly in the pharmacological treatment of schizophrenia. This review provides an overview of the pharmacological and clinical characteristics of atypical antipsychotics. In particular we discuss their efficacy in treating psychotic and negative symp...

journal_title：Swiss medical weekly

authors： Bridler R,Umbricht D

更新日期：2003-02-08 00:00:00

abstract：BACKGROUND:Although most experts recommend empirical antibiotic treatment, covering also atypical bacteria, for patients admitted to an intensive care unit (ICU), the data are not clear for patients admitted to a general ward. European guidelines recommend starting empirical treatment with a beta-lactam antibiotic with...

journal_title：Swiss medical weekly

authors： Piso RJ,Arnold C,Bassetti S

更新日期：2013-09-19 00:00:00

abstract：OBJECTIVE:The first description of the simplified acute physiology score (SAPS) II dates back to 1993, but little is known about its accuracy in daily practice. Our purpose was to evaluate the accuracy of scoring and the factors that affect it in a nationwide survey. METHODS:Twenty clinical scenarios, covering a broad...

journal_title：Swiss medical weekly

authors： Previsdomini M,Cerutti B,Merlani P,Kaufmann M,van Gessel E,Rothen HU,Perren A

更新日期：2014-12-23 00:00:00

abstract：BACKGROUND:A clinical research application must be submitted for approval by a competent ethics committee (EC) before a study can be executed. There is very limited information on how such submissions could be optimised, especially regarding research in children and adolescents, which requires particular caution and ag...

journal_title：Swiss medical weekly

authors： Bergstraesser E,Nadal D,Özgü H,Kleist P

更新日期：2020-06-19 00:00:00

abstract：OBJECTIVE:The methods used to diagnose and classify ovarian cancer have changed over the past decade. We used hospital registry data to assess the incidence, treatment durations and hospital costs of ovarian cancer in Switzerland. METHODS:We carried out a retrospective analysis of a hospital registry covering all inpa...

journal_title：Swiss medical weekly

authors： Wieser S,Schmidt M,Kind AB,Heinzelmann-Schwarz VA

更新日期：2018-07-29 00:00:00

abstract：QUESTIONS UNDER STUDY:In the next Swiss National HIV and Sexually Transmitted Infection (STI) Strategy 2011-2017, STI control will be integrated with HIV prevention. Information is needed which will improve the targeting of professional education. The objective of this study was to describe the clinical specialities an...

journal_title：Swiss medical weekly

authors： Baillif A,Low N

更新日期：2011-01-20 00:00:00

abstract：:Idiopathic pulmonary fibrosis (IPF) is a chronic and usually progressive lung disorder of unknown aetiology. Conventional management of patients with IPF has been primarily based on the concept that suppressing inflammation would prevent progression to fibrosis. Although the pathogenesis is incompletely understood, it...

journal_title：Swiss medical weekly

authors： Geiser T

更新日期：2003-07-26 00:00:00

abstract：:A rapid start of post-exposure prophylaxis with an antiretroviral regime is recommended after percutaneous exposure to blood from an HIV-positive source. Since the HIV-antibody status of the source is usually not known at the time of injury, antiretroviral treatment is started pending the results of HIV testing of the...

journal_title：Swiss medical weekly

authors： King AM,Osterwalder JJ,Vernazza PL

更新日期：2001-01-12 00:00:00

abstract：BACKGROUND:In recent years, several treatment modalities have proved to be effective in the treatment of neuroendocrine tumours (NETs). However, there is currently no consensus on the sequence in which these options are best used. METHODS:In this observational study, we analysed the treatment modalities and sequences ...

journal_title：Swiss medical weekly

authors： Kollar A,Bütikofer L,Ochsenbein A,Stettler C,Trepp R

更新日期：2020-01-15 00:00:00

abstract：OBJECTIVES:Women are still underrepresented in the senior ranks of medical school faculties. Thus far information has been lacking on gendersensitive career paths for professorial and nonprofessorial staff of Swiss medical schools. The aim of this study was to survey faculty members of all Swiss medical schools on soci...

journal_title：Swiss medical weekly

authors： Buddeberg-Fischer B,Leemann R,Klaghofer R

更新日期：2003-05-31 00:00:00

abstract：BACKGROUND:Organs donated for transplantation remain a scarce resource in Switzerland. One of the reasons for this situation is the high percentage of patients or families who refuse to consent to donation. This study aimed to provide an overview of attitudes towards organ donation among Swiss residents, including any ...

journal_title：Swiss medical weekly

authors： Weiss J,Shaw D,Schober R,Abati V,Immer FF,Comité National du Don d'Organes Cndo

更新日期：2017-02-03 00:00:00

abstract：PURPOSE:Stress ulcer prophylaxis prescriptions might not be sufficiently challenged throughout a patient's stay in an intensive care unit (ICU) and might be erroneously maintained after ICU discharge. This study aimed to determine (1) stress ulcer prophylaxis adequacy in ICU and (2) the proportion of patients recei...

journal_title：Swiss medical weekly

authors： Franchitti M,Piubellini J,Sadeghipour F,Eckert P,Voirol P,Schneider AG

更新日期：2020-08-24 00:00:00

abstract：PRINCIPLES:MELAS, or mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes is a new distinctive clinical entity. The current study was designed to assess ascending aortic elasticity in adult patients with MELAS syndrome and in gene carriers, and to compare the results with age- and gender-mat...

journal_title：Swiss medical weekly

authors： Nemes A,Geleijnse ML,Sluiter W,Vydt TC,Soliman OI,van Dalen BM,Vletter WB,ten Cate FJ,Smeets HJ,de Coo RF

更新日期：2009-02-21 00:00:00

abstract：BACKGROUND:B-type natriuretic peptide (BNP) has been proven to be a biochemical marker of severity of congestive heart failure. We are aware of only few papers reporting the association of BNP elevation and pulmonary hypertension (primary, thromboembolic, or as a consequence of chronic obstructive pulmonary disease). L...

journal_title：Swiss medical weekly

authors： Maeder M,Ammann P,Rickli H,Diethelm M

更新日期：2003-09-26 00:00:00

abstract：:Alzheimer's disease (AD) is a neurodegenerative disorder and the most common cause for dementia, which affects approximately 120 thousand people in Switzerland and 35 million worldwide. Aging is a major risk factor for developing AD and thus, as our societies are growing older, we face great challenges to find treatme...

journal_title：Swiss medical weekly

authors： Konietzko U

更新日期：2015-12-23 00:00:00

abstract：INTRODUCTION:It has been proposed that reactive oxygen species play a role in renal fibrosis. 8-OHdG, a metabolite of oxidative damage to leukocyte DNA, has been identified as a marker of oxidative stress in patients with chronic renal failure. MATERIALS AND METHODS:Seventy-four patients following nephrectomy were ret...

journal_title：Swiss medical weekly

authors： Tsai JP,Liou JH,Yeh KT,Tai HC,Cheng YW,Chang HR

更新日期：2011-10-12 00:00:00

abstract：:Advance directives emerged in the 1960s with the goal of empowering people to exert control over their future medical decisions. However, it has become apparent, over recent years, that advance directives do not sufficiently capture the temporal and relational aspects of planning treatment and care. Advance care plann...

journal_title：Swiss medical weekly

authors： Bosisio F,Jox RJ,Jones L,Rubli Truchard E

更新日期：2018-12-30 00:00:00

abstract：:Beta-haemolytic streptococci of groups C and G have become increasingly recognized as causes of invasive human infections. We reviewed clinical and molecular characteristics of Streptococcus dysgalactiae isolates that caused bacteraemia in adults from 2006 to 2015. Among 67 episodes, skin and soft-tissue infections (4...

journal_title：Swiss medical weekly

authors： Ruppen C,Rasmussen M,Casanova C,Sendi P

更新日期：2017-07-24 00:00:00

abstract：:The atherogenic lipoprotein phenotype is characterised by a moderate increase in plasma triglycerides, a decrease in high density lipoprotein cholesterol and the prevalence of smaller denser low density lipoprotein particles. The prevalence of this partially inheritable phenotype is approximately 30% and is a feature ...

journal_title：Swiss medical weekly

authors： Berneis K,Rizzo M

更新日期：2004-12-18 00:00:00

abstract：PRINCIPLES:Cardiac myxoma is the most commonly diagnosed cardiac tumour. Infection of herpes simplex virus 1 (HSV1) has been postulated to be a factor for this pathologic entity. The aim of the current study was to evaluate the association between HSV 1 and myxoma occurrence. METHODS:Between 1965 and 2005, 70 patients...

journal_title：Swiss medical weekly

authors： Schurr UP,Berdajs DA,Bode B,Dzemali O,Emmert MY,Genoni M

更新日期：2011-08-26 00:00:00