APOE epsilon status in Hungarian patients with primary progressive multiple sclerosis.

abstract：:Osteoarticular infections remain a significant cause of morbidity worldwide in young children. They can have a devastating impact with a high rate of serious and long-lasting sequelae, especially on remaining growth. Depending on the localisation of infection, they manifest as osteomyelitis, septic arthritis, a combin...

journal_title：Swiss medical weekly

authors： Ceroni D,Kampouroglou G,Valaikaite R,Anderson della Llana R,Salvo D

更新日期：2014-06-12 00:00:00

abstract：:The humble house mouse has long been a workhorse model system in biomedical research. The technology for introducing site-specific genome modifications led to Nobel Prizes for its pioneers and opened a new era of mouse genetics. However, this technology was very time-consuming and technically demanding. As a result, m...

journal_title：Swiss medical weekly

authors： Kaczmarczyk L,Jackson WS

更新日期：2015-10-29 00:00:00

abstract：AIMS OF THE STUDY:To describe patterns of systemic lupus erythematosus (SLE) care and the clinical effectiveness of belimumab plus standard of care therapy in a real-world clinical setting in Switzerland. METHODS:This multicentre, observational, retrospective cohort study included adults with SLE who initiated belimum...

journal_title：Swiss medical weekly

authors： von Kempis J,Duetsch S,Reuschling N,Villiger R,Villiger PM,Vallelian F,Schaer DJ,Mueller RB

更新日期：2019-03-10 00:00:00

abstract：QUESTIONS UNDER STUDY:In the next Swiss National HIV and Sexually Transmitted Infection (STI) Strategy 2011-2017, STI control will be integrated with HIV prevention. Information is needed which will improve the targeting of professional education. The objective of this study was to describe the clinical specialities an...

journal_title：Swiss medical weekly

authors： Baillif A,Low N

更新日期：2011-01-20 00:00:00

abstract：BACKGROUND:Renal replacement therapy for paediatric end-stage renal disease (ESRD) has developed steadily since its introduction five decades ago. Continuous and long-term analysis of patient outcomes is essential for quality control. METHODS:The Swiss Paediatric Renal Registry, founded in 1970, includes patients diag...

journal_title：Swiss medical weekly

authors： Maurer E,Neuhaus TJ,Weitz M,Kuehni CE,Laube GF

更新日期：2020-07-27 00:00:00

abstract：QUESTION UNDER STUDY:The present study aimed to compare the prevalence of work-life conflicts and the health status of physicians, with a representative sample of university graduates as well as with a representative sample of the general Swiss working population. Furthermore, it aimed to analyse whether work-life conf...

journal_title：Swiss medical weekly

authors： Knecht M,Bauer GF,Klaghofer R,Buddeberg-Fischer B,Stamm M,Hämmig O

更新日期：2010-07-11 00:00:00

abstract：:Advance directives emerged in the 1960s with the goal of empowering people to exert control over their future medical decisions. However, it has become apparent, over recent years, that advance directives do not sufficiently capture the temporal and relational aspects of planning treatment and care. Advance care plann...

journal_title：Swiss medical weekly

authors： Bosisio F,Jox RJ,Jones L,Rubli Truchard E

更新日期：2018-12-30 00:00:00

abstract：PRINCIPLES:Since the recommendation that infants sleep in the supine position, there has been an increase in cases of posterior positional plagiocephaly. Even though this condition is a purely cosmetic problem, if it is severe it may affect the child psychologically. Positioning may help in mild or moderate cases, but ...

journal_title：Swiss medical weekly

authors： de Ribaupierre S,Vernet O,Rilliet B,Cavin B,Kalina D,Leyvraz P-

更新日期：2007-06-30 00:00:00

abstract：PRINCIPLES:We aimed to evaluate the efficacy of, and treatment satisfaction with, insulin glargine administered with SoloSTAR® or ClikSTAR® pens in patients with type 2 diabetes mellitus managed by primary care physicians in Switzerland. METHODS:A total of 327 patients with inadequately controlled type 2 diabetes were...

journal_title：Swiss medical weekly

authors： Riebenfeld D,Spirk D,Mathis A,Villiger L,Gerber PA,Gasser UE,Lehmann R

更新日期：2015-03-05 00:00:00

abstract：BACKGROUND:Although airway obstruction, as defined by improvement of forced expiratory volume in one second (FEV1) and/or forced vital capacity (FVC), is irreversible in patients with COPD, they clearly seem to benefit from treatment with inhaled bronchodilators. AIMS:To assess the response pattern of residual volume ...

journal_title：Swiss medical weekly

authors： Balestra AM,Bingisser RB,Chhajed PN,Tamm M,Leuppi JD

更新日期：2008-05-03 00:00:00

abstract：OBJECTIVES:The sero-prevalence of co-infection with the hepatitis B virus (HBV) and the hepatitis D virus (HDV) is well known in many European countries, starting from 6.8% in Germany to more than 27% in some Turkish areas. To gain a better description of this infection in Switzerland, and to characterise those affecte...

journal_title：Swiss medical weekly

authors： Genné D,Rossi I

更新日期：2011-03-18 00:00:00

abstract：THEORETICAL BACKGROUND:Mental disorders emerge in childhood and adolescence and are important risk factors for mental disorders in adolescence and adulthood. Since paediatricians are typically the first to see children with psychological problems, the aim of this study was to obtain a survey of mental disorders of chil...

journal_title：Swiss medical weekly

authors： In-Albon T,Zumsteg U,Müller D,Schneider S

更新日期：2010-08-27 00:00:00

abstract：:Rheumatoid arthritis is a common chronic inflammatory disease that causes progressive synovial inflammation resulting in irreversible joint destruction, chronic disability and premature mortality. Although it is recognised that in rheumatoid arthritis, inflammation and its persistence result from complex interactions ...

journal_title：Swiss medical weekly

authors： Juarez M,Filer A,Buckley CD

更新日期：2012-02-24 00:00:00

abstract：:The antineutrophil cytoplasmic antibody (ANCA) associated vasculitides (AAV) are a group of primary vasculitides that affect predominantly small- to medium-sized blood vessels. AAV include granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA) and eosinophilic granulomatosis with polyangiitis (EGPA). D...

journal_title：Swiss medical weekly

authors： Daikeler T,Kistler AD,Martin PY,Vogt B,Huynh-Do U

更新日期：2015-02-06 00:00:00

abstract：QUESTIONS UNDER STUDY:Postmenopausal women are more likely to develop coronary artery disease than premenopausal women of the same age. Postmenopausal oral oestrogen therapy is associated with increased levels of high-density lipoprotein (HDL) cholesterol and decreased levels of lowdensity lipoprotein (LDL) cholesterol...

journal_title：Swiss medical weekly

authors： Delibasi T,Kockar C,Celik A,Kockar O

更新日期：2006-08-05 00:00:00

abstract：BACKGROUND:Introduction of potent antiretroviral combination therapy (ART) has reduced overall morbidity and mortality amongst HIV-infected adults. Some prophylactic regimes against opportunistic infections can be discontinued in patients under successful ART. QUESTIONS UNDER STUDY:(1) The influence of the availabilit...

journal_title：Swiss medical weekly

authors： Rossi M,Flepp M,Telenti A,Schiffer V,Egloff N,Bucher H,Vernazza P,Bernasconi E,Weber R,Rickenbach M,Furrer H,Swiss HIV Cohort Study.

更新日期：2001-08-11 00:00:00

abstract：:Although progress has been made in the management of acute leukaemias, most patients who fail to respond to front-line therapies with cytostatic agents and stem cell transplantation, or who relapse after an initial response die from progressive disease. Novel treatment modalities exploiting donor-derived natural kille...

journal_title：Swiss medical weekly

authors： Wodnar-Filipowicz A,Kalberer CP

更新日期：2006-06-10 00:00:00

abstract：UNLABELLED:The goal of this study was to assess the feasibility, safety and success of a system which uses radiofrequency energy (RFE) rather than a device for percutaneous closure of patent foramen ovale (PFO). METHODS:Sixteen patients (10 men, 6 women, mean age 50 years) were included in the study. All of them had a...

journal_title：Swiss medical weekly

authors： Walpoth NB,Habermacher K,Moarof I,Watson S,Wahl A,Windecker S,Schönenberger C,Meier B

更新日期：2008-02-23 00:00:00

abstract：OBJECTIVE:To investigate whether olfactory performance decreases as a function of the number of pregnancies, previous research having indicated that olfactory function decreases in the course of pregnancy. METHODS:In a prospective study three groups of women were investigated (total n = 93), women who have given birth...

journal_title：Swiss medical weekly

authors： Wohlgemuth C,Beinder E,Ochsenbein-Kölble N,Hummel T

更新日期：2008-08-09 00:00:00

abstract：BACKGROUND:The precision of symptom assessment and documentation in daily routine is unknown. Differences in hip studies have been observed between the charts and the patient questionnaires. This was the reason to perform this study and to compare the charts and the patient questionnaires. METHODS:This was a retrospec...

journal_title：Swiss medical weekly

authors： Huber JF,Dabis E,Huesler J,Ruflin GB

更新日期：2009-10-17 00:00:00

abstract：:Multicentric carpotarsal osteolysis (MCTO) is an autosomal dominant disease of the skeleton characterised by progressive destruction of carpal and tarsal bones. Recently, it has been demonstrated that this disease is caused by heterozygous mutations in the gene for the transcriptional repressor MAFB. We analysed genom...

journal_title：Swiss medical weekly

authors： Zhuang L,Adler S,Aeberli D,Villiger PM,Trueb B

更新日期：2017-10-27 00:00:00

abstract：PRINCIPLES:3435C>T, a single nucleotide polymorphism (SNP) in exon 26 of the MDR1 gene, is linked to the variability of P-gp expression and function among different individuals. It was found that ethnic differences exist in the polymorphism of the MDR1(C3435T) gene. However, the distribution of 3435C>T genotypes in the...

journal_title：Swiss medical weekly

authors： Li Y,Wang Y,Sun J,Li Y,Yang L

更新日期：2006-06-10 00:00:00

abstract：QUESTION UNDER STUDY:Switzerland has been receiving migrants of various origins for more than 50 years. The adoption of risk-taking behaviours among migrant youths is unclear. Moreover, when studied, migrant youths are rarely analysed according to whether they are first or second generation, or just young people with m...

journal_title：Swiss medical weekly

authors： Campisi L,Berchtold A,Barrense-Dias Y,Akre C,Gehri M,Suris JC

更新日期：2017-11-08 00:00:00

abstract：:Over the last few years atypical antipsychotics have been used increasingly in the pharmacological treatment of schizophrenia. This review provides an overview of the pharmacological and clinical characteristics of atypical antipsychotics. In particular we discuss their efficacy in treating psychotic and negative symp...

journal_title：Swiss medical weekly

authors： Bridler R,Umbricht D

更新日期：2003-02-08 00:00:00

abstract：BACKGROUND:Based on a reduction in morbidity and mortality, cardiac resynchronisation therapy (CRT) has evolved as a standard therapy for patients with advanced heart failure. OBJECTIVE:To provide insight into patient demographics, safety, echocardiographic remodelling and long-term follow-up of patients treated with ...

journal_title：Swiss medical weekly

authors： Winnik S,Elsener C,Seifert B,Starck C,Straub A,Saguner AM,Breitenstein A,Krasniqi N,Wilhelm MJ,Haegeli L,Duru F,Benussi S,Maisano F,Lüscher TF,Holzmeister J,Huerlimann D,Ruschitzka F,Steffel J

更新日期：2017-04-18 00:00:00

abstract：:Pulmonary rehabilitation is a form of therapy for patients with chronic lung disease that is evidence based, which ameliorates performance and endurance of the patient and improves quality of life significantly. Pulmonary rehabilitation also diminishes the amount of hospitalisations and the duration of stay in hospita...

journal_title：Swiss medical weekly

authors： Karrer W

更新日期：2005-02-05 00:00:00

abstract：AIMS:We aimed to identify familial hypercholesterolaemia mutation carriers among participants to the Lausanne Institutional Biobank (BIL). Our experimental workflow was designed as a proof-of-concept demonstration of the resources and services provided by our integrated institutional clinical research support platform....

journal_title：Swiss medical weekly

authors： Maurer F,Pradervand S,Guilleret I,Nanchen D,Maghraoui A,Chapatte L,Bojkowska K,Bhuiyan ZA,Jacquemont N,Harshman K,Mooser V

更新日期：2016-08-06 00:00:00

abstract：:Each year, over 5 million people die worldwide from stroke, and at least every sixth patient who survives will experience another stroke within five years [1]. We are therefore eager to advance early and rapid diagnosis, prognosis and optimal risk stratification, as well as secondary prevention. In this context, blood...

journal_title：Swiss medical weekly

authors： Sonderer J,Katan Kahles M

更新日期：2015-05-29 00:00:00

abstract：OBJECTIVES:To investigate the subjective treatment goals of insulin-treated diabetic patients. METHODS:297 type 1 and 205 type 2 diabetic patients, representative of the North-western Swiss population, filled out a self report questionnaire focusing on their own treatment goals using standardized measures wherever ava...

journal_title：Swiss medical weekly

authors： Puder JJ,Endrass J,Moriconi N,Keller U

更新日期：2006-09-02 00:00:00

abstract：OBJECTIVES:First, to test whether current injury is more closely related to acute intake than to usual consumption patterns, and second, to test whether repeated injury is more closely related to general consumption patterns than to acute intake. METHODS:Screening of alcohol consumption of 7,872 patients enrolling bet...

journal_title：Swiss medical weekly

authors： Gmel G,Givel JC,Yersin B,Daeppen JB

更新日期：2007-11-17 00:00:00