Abstract:
UNLABELLED:The goal of this study was to assess the feasibility, safety and success of a system which uses radiofrequency energy (RFE) rather than a device for percutaneous closure of patent foramen ovale (PFO). METHODS:Sixteen patients (10 men, 6 women, mean age 50 years) were included in the study. All of them had a proven PFO with documented right-to-left shunt (RLS) after Valsalva manoeuvre (VM) during transoesophageal echocardiography (TEE). The patients had an average PFO diameter of 6 +/- 2 mm at TEE and an average of 23 +/- 4 microembolic signals (MES) in power M-mode transcranial Doppler sonography (pm-TCD), measured over the middle cerebral artery. An atrial septal aneurysm (ASA) was present in 7 patients (44%). Balloon measurement, performed in all patients, revealed a stretched PFO diameter of 8 +/- 3 mm. In 2 patients (stretched diameter 11 and 14 mm respectively, both with ASA >10 mm), radiofrequency was not applied (PFO too large) and the PFO was closed with an Amplatzer PFO occluder instead. A 6-month follow-up TEE was performed in all patients. RESULTS:There were no serious adverse events during the procedure or at follow-up (12 months average). TEE 6 months after the first RFE procedure showed complete closure of the PFO in 50% of the patients (7/14). Closure appeared to be influenced by PFO diameter, complete closure being achieved in 89% (7/8) with a balloon-stretched diameter < or =7 mm but in none of the patients >7 mm. Only one of the complete closure patients had an ASA. Of the remainder, 4 (29%) had an ASA. Although the PFO was not completely closed in this group, some reduction in the diameter of the PFO and in MES was documented by TEE and pm-TCD with VM. Five of the 7 residual shunt patients received an Amplatzer PFO occluder. Except for one patient with a minimal residual shunt, all showed complete closure of PFO at 6-month follow-up TEE and pm-TCD with VM. The other two refused a closure device. CONCLUSIONS:The results confirm that radiofrequency closure of the PFO is safe albeit less efficacious and more complex than device closure. The technique in its current state should not be attempted in patients with a balloon-stretched PFO diameter >7 mm and an ASA.
journal_name
Swiss Med Wklyjournal_title
Swiss medical weeklyauthors
Walpoth NB,Habermacher K,Moarof I,Watson S,Wahl A,Windecker S,Schönenberger C,Meier Bdoi
2008/07/smw-12182subject
Has Abstractpub_date
2008-02-23 00:00:00pages
108-13issue
7-8eissn
1424-7860issn
1424-3997pii
smw-12182journal_volume
138pub_type
临床试验,杂志文章abstract:AIMS OF THE STUDY:The Cancer Registry Zurich, Zug, Schaffhausen and Schwyz is one of the oldest cancer registries in Switzerland, first registering tumours in 1980 for the canton of Zurich. The aim of this study was to analyse trends in incidence and mortality for the most common types of cancer in the canton of Zurich...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2020.20388
更新日期:2020-12-14 00:00:00
abstract:BACKGROUND AND AIM:Perinatal and infant mortality rates are considered key indicators of medical care. The aim of this investigation was to examine how representative and reliable the official national figures of Switzerland are by comparing them with the data in local birth registers. METHODS:124 of 156 maternity hos...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2005/29/smw-10946
更新日期:2005-07-23 00:00:00
abstract:PRINCIPLES:Heart failure is associated with a grim prognosis. Disease management programmes can improve prognosis in heart failure patients but the applicability to the general population remains limited. We aimed to compare the outcome, pharmacological therapy, and quality of life in unselected heart failure patients ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2006/17/smw-11274
更新日期:2006-04-29 00:00:00
abstract:OBJECTIVE:To investigate whether olfactory performance decreases as a function of the number of pregnancies, previous research having indicated that olfactory function decreases in the course of pregnancy. METHODS:In a prospective study three groups of women were investigated (total n = 93), women who have given birth...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2008/31/smw-12200
更新日期:2008-08-09 00:00:00
abstract:QUESTION UNDER STUDY:What are the trends in avoidable cancer mortality in Switzerland and neighbouring countries? METHODS:Mortality data and population estimates 1996-2010 were obtained from the Swiss Federal Statistical Office for Switzerland and the World Health Organization Mortality Database (http://www.who.int/he...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2015.14184
更新日期:2015-10-02 00:00:00
abstract::Invasive fungal infections have emerged as important causes of morbidity and mortality in immunocompromised patients. In response to this challenge, the field of antifungal chemotherapy has considerably expanded. Fluconazole and itraconazole, introduced in the late 1980s, were the first durably useful alternatives to ...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:2002/23/smw-09729
更新日期:2002-06-15 00:00:00
abstract:OBJECTIVE:An increasing number of patients with asthma are attracted by complementary and alternative medicine (CAM). Therefore, it is of importance that scientific evidence about the efficacy of this type of therapy is regarded. METHOD:We searched the electronic databases Medline, Embase and the Cochrane Library for ...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:2002/25/smw-09972
更新日期:2002-06-29 00:00:00
abstract:BACKGROUND:Extracorporeal photopheresis (ECP) has been reported to be safe and the ultimate treatment option in lung transplant recipients with chronic lung allograft dysfunction (CLAD), the main overall cause of mortality in lung transplant recipients. However, ECP is not reimbursed in selected health jurisdictions, a...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2017.14429
更新日期:2017-03-13 00:00:00
abstract:BACKGROUND:Considerable criticism has lately been raised by the media regarding the quality of Swiss medical expertises. The present investigation was therefore undertaken to assess the professional quality of Swiss medical expertises. The study was part of a market analysis of medical expertises (MGS study). METHODS:...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2011.13173
更新日期:2011-03-04 00:00:00
abstract::The precise diagnosis of a severe haemorrhagic disorder is usually not too problematic. However, physicians are most often faced with individuals consulting for mild haemorrhagic symptoms, particularly occurring after a surgical intervention. The problem here is to evaluate whether this person really has a bleeding di...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:smw-12476
更新日期:2009-06-13 00:00:00
abstract::In Switzerland, approximately 350,000 people aged 70 years or older own a valid driving license. By law, these drivers are medically assessed every other year, most commonly by their general practitioner, to exclude that a medical condition is interfering with their driving skills. A prerequisite for driving is the in...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:10.4414/smw.2011.13136
更新日期:2011-01-17 00:00:00
abstract:BACKGROUND:Endoscopic retrograde biliary drainage (ERBD) using a plastic stent is suggested to be as effective as endoscopic nasobiliary drainage (ENBD) with a nasobiliary catheter for temporary biliary drainage in acute obstructive cholangitis. However, there are few studies that have compared the two methods. We ther...
journal_title:Swiss medical weekly
pub_type: 杂志文章,随机对照试验
doi:10.4414/smw.2013.13823
更新日期:2013-07-07 00:00:00
abstract:PRINCIPLES:Neisseria gonorrhoeae (NG) resistant to ciprofloxacin (CR) was documented for the first time in Geneva in 2002 and increased from 7% that year to 47% in 2005. We describe NG cases during this period and compare characteristics of CR and ciprofloxacin susceptible (CS) cases. METHOD:Geneva microbiological lab...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2008/15/smw-12029
更新日期:2008-04-19 00:00:00
abstract:BACKGROUND:Several publications reported on the safety and efficacy of bortezomib, a novel first-in-class anti-cancer agent, in the treatment of relapsed/refractory multiple myeloma in controlled clinical trials. Complementary data on the experience with bortezomib in daily oncology practice are needed. We report on th...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2007/21/smw-11716
更新日期:2007-06-02 00:00:00
abstract:QUESTIONS UNDER STUDY:Paraoxonase-1 (PON1) is an HDL-bound enzyme system which plays a key role in the protection of LDL and HDL from oxidation by hydrolysing activated phospholipids and lipid peroxide products. Oxidative stress has been involved in the pathogenesis of many complications of human pregnancy, including e...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:smw-12495
更新日期:2009-02-07 00:00:00
abstract::Giant cell arteritis (GCA) is the most common of the vasculitis syndromes and, being a disease of the elderly, its incidence is increasing with the general ageing of the population. GCA is most feared for its early complications, namely blindness and stroke, resulting from inflammation and subsequent occlusion of ocul...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:10.4414/smw.2011.13272
更新日期:2011-09-28 00:00:00
abstract:BACKGROUND:Low-molecular-weight heparins (LMWH) have been shown to be safer, more effective and more convenient than unfractionated heparin (UFH) in many clinical situations. However, their use is limited in patients with renal insufficiency (RI) due to bioaccumulation. METHOD:The literature is critically reviewed and...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:smw-11284
更新日期:2009-08-08 00:00:00
abstract:QUESTIONS UNDER STUDY/PRINCIPLES:We describe the proportion of severely depressed outpatients reaching complete remission at the different stages of a drug treatment algorithm. We compare several treatment options for SSRI (selective serotonin reuptake inhibitor) non-responders and test the feasibility of the algorithm...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2006/05/smw-11267
更新日期:2006-02-04 00:00:00
abstract:QUESTIONS UNDER STUDY / PRINCIPLES:Colonoscopies are complex procedures that depend greatly on the patient's cooperation and on the correct judgment of a tolerable amount of discomfort by the endoscopy team, even in sedated patients. Little is known regarding the accuracy of the patient comfort level assessments made b...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2012.13726
更新日期:2012-11-05 00:00:00
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journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2019.20033
更新日期:2019-03-24 00:00:00
abstract:QUESTIONS UNDER STUDY/PRINCIPLES:A retrospective assessment of long-term results on a single centre, single author experience in treating prostate cancer with high dose curative radiotherapy (RT) with or without androgen deprivation (AD). METHODS:Between 1991 and 2004, 408 patients with clinically localised prostate c...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:smw-12604
更新日期:2009-09-05 00:00:00
abstract:BACKGROUND:In contrast to quality of life, patient satisfaction on chronic haemodialysis (HD) and peritoneal dialysis (PD) has only rarely been studied. PATIENTS AND METHODS:All chronic HD and PD patients of the 19 centres located in western Switzerland were asked to complete a specific questionnaire, assessing dialys...
journal_title:Swiss medical weekly
pub_type: 杂志文章,多中心研究
doi:2006/13/smw-11180
更新日期:2006-04-01 00:00:00
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journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2011.13223
更新日期:2011-08-26 00:00:00
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journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2015.14098
更新日期:2015-02-09 00:00:00
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journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2008/23/smw-12102
更新日期:2008-06-14 00:00:00
abstract:OBJECTIVE:To evaluate the current prevalence of self-reported interpersonal violence amongst patients consulting at the emergency department (ED) of a university hospital and to describe the characteristics of the violence sustained. METHODS:Ours was a cross-sectional study using a modified version of the Partner Viol...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2019.20147
更新日期:2019-12-17 00:00:00
abstract::A growing body of evidence supports preventive interventions in asymptomatic adults. Primary prevention, which includes counselling (in particular for smoking cessation) and review of immunisation status, has been shown to be more cost-effective than secondary prevention. Evidence supports screening for hypertension, ...
journal_title:Swiss medical weekly
pub_type: 杂志文章,评审
doi:2002/27/smw-09920
更新日期:2002-07-13 00:00:00
abstract:AIMS:In comparison with other central European countries, Switzerland has a high prevalence of gun ownership and a high rate of suicide by shooting. After the Army XXI reform in 2003, which reduced personnel from about 400,000 to approximately 200,000, a decline in suicides by firearms and a decline in the total number...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2018.14646
更新日期:2018-09-23 00:00:00
abstract::No abstract available (Letter to the editor). ...
journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:10.4414/smw.2012.13639
更新日期:2012-07-17 00:00:00
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journal_title:Swiss medical weekly
pub_type: 杂志文章
doi:2006/39/smw-11357
更新日期:2006-09-30 00:00:00