Antifungal chemotherapy: advances and perspectives.

abstract：OBJECTIVE:The aim of this study was to examine the impact of patients' ethnic diversity on the patient satisfaction rates. DESIGN:We used the methodology developed in an international EUROPE study. The patients were asked to fill in self-administered questionnaires on their evaluations of the care received in the year...

journal_title：Swiss medical weekly

authors： Kersnik J,Ropret T

更新日期：2002-03-09 00:00:00

abstract：OBJECTIVE:To assess outcomes 24 months after treatment start for multidrug-resistant tuberculosis (MDR-TB). METHODS:Cohort study of all culture-positive MDR-TB cases notified in Switzerland from 01/2003 to 07/2010. RESULTS:Fifty-one cases were observed, with a median age of 26 years (range 2-56). Twenty-seven were ma...

journal_title：Swiss medical weekly

authors： Helbling P,Altpeter E,Egger JM,Zellweger JP

更新日期：2014-12-04 00:00:00

abstract：PRINCIPLES:Neuroendocrine neoplasms (NENs) are believed to be associated with an increased risk for additional malignancies (AMs). We aimed to (1) assess the occurrence of AM in NEN patients (2) investigate the characteristics and temporal relationship of NEN patients with and without AM. METHODS:The SwissNET registry...

journal_title：Swiss medical weekly

authors： Kollár A,Blank A,Perren A,Bütikofer L,Stettler C,Christ E

更新日期：2016-11-12 00:00:00

abstract：:Sequencing the human genome was the big challenge of the last decade. Ten years later, the large amount of DNA sequences accumulated in our databases allows us to look at genome variations between humans. The level of complexity of these variations is much higher than previously expected. It goes from changes in the n...

journal_title：Swiss medical weekly

authors： Paoloni-Giacobino A

更新日期：2011-12-19 00:00:00

abstract：AIMS OF THE STUDY:To describe patterns of systemic lupus erythematosus (SLE) care and the clinical effectiveness of belimumab plus standard of care therapy in a real-world clinical setting in Switzerland. METHODS:This multicentre, observational, retrospective cohort study included adults with SLE who initiated belimum...

journal_title：Swiss medical weekly

authors： von Kempis J,Duetsch S,Reuschling N,Villiger R,Villiger PM,Vallelian F,Schaer DJ,Mueller RB

更新日期：2019-03-10 00:00:00

abstract：QUESTIONS UNDER STUDY:The unexpected death of a preterm infant is an extremely painful situation for parents. Despite a number of quantitative studies, little is known about parents' inner experience. The aim of this study was to gather more in-depth information about what preoccupies parents in this situation of suffe...

journal_title：Swiss medical weekly

authors： Glaser A,Bucher HU,Moergeli H,Fauchère JC,Buechi S

更新日期：2007-07-14 00:00:00

abstract：OBJECTIVE:Coronary artery bypass grafting (CABG) remains the gold standard for complex revascularisation in multivessel disease. The concept of the minimally invasive extracorporeal circulation circuit (MiECC) was introduced to minimise pathophysiological side effects of conventional extracorporeal circulation. This st...

journal_title：Swiss medical weekly

authors： Winkler B,Heinisch PP,Zuk G,Zuk K,Gahl B,Jenni HJ,Kadner A,Huber C,Carrel T

更新日期：2017-07-10 00:00:00

abstract：BACKGROUND:Low-molecular-weight heparins (LMWH) have been shown to be safer, more effective and more convenient than unfractionated heparin (UFH) in many clinical situations. However, their use is limited in patients with renal insufficiency (RI) due to bioaccumulation. METHOD:The literature is critically reviewed and...

journal_title：Swiss medical weekly

authors： Schmid P,Fischer AG,Wuillemin WA

更新日期：2009-08-08 00:00:00

abstract：:Mantle cell lymphoma (MCL) is a relatively rare lymphoma entity accounting for an estimated 3%-6% of all non-Hodgkin's lymphoma cases. Characterised by both the incurability of indolent lymphomas and the rapid growth of aggressive lymphomas, MCL has a median overall survival of only 4-5 years. Although the disease oft...

journal_title：Swiss medical weekly

authors： Hitz F,Bargetzi M,Cogliatti S,Lohri A,Taverna C,Renner C,Mey U

更新日期：2013-11-13 00:00:00

abstract：BACKGROUND:In contrast to quality of life, patient satisfaction on chronic haemodialysis (HD) and peritoneal dialysis (PD) has only rarely been studied. PATIENTS AND METHODS:All chronic HD and PD patients of the 19 centres located in western Switzerland were asked to complete a specific questionnaire, assessing dialys...

journal_title：Swiss medical weekly

authors： Wasserfallen JB,Moinat M,Halabi G,Saudan P,Perneger T,Feldman HI,Martin PY,Wauters JP

更新日期：2006-04-01 00:00:00

abstract：QUESTIONS UNDER STUDY:Suicidal behaviour is a major source of burden of disease. While most studies focus on cost associated with completed suicides, data on costs of, non-lethal, suicide attempts are lacking. The aim of this study was to assess direct annual cost of suicide attempts in Basel in 2003 from a health serv...

journal_title：Swiss medical weekly

authors： Czernin S,Vogel M,Flückiger M,Muheim F,Bourgnon JC,Reichelt M,Eichhorn M,Riecher-Rössler A,Stoppe G

更新日期：2012-07-23 00:00:00

abstract：QUESTIONS UNDER STUDY:This study aims at estimating the costs of disorders of the brain in Switzerland based on the published epidemiological and economic evidence. METHODS:the data presented for Switzerland are derived from the "cost of disorders of the brain in Europe" study of the European Brain Counsil (EBC). Avai...

journal_title：Swiss medical weekly

authors： Jäger M,Sobocki P,Rössler W

更新日期：2008-01-12 00:00:00

abstract：BACKGROUND:Hypoxia-inducible factor-1α (HIF-1α) plays an important role in tumour progression and metastasis through activation of many target genes that are especially involved in pivotal aspects of cancer biology. However, the prognostic role of HIF-1α has been controversial in primary patients with lung cancer. This...

journal_title：Swiss medical weekly

authors： Ren W,Mi D,Yang K,Cao N,Tian J,Li Z,Ma B

更新日期：2013-09-06 00:00:00

abstract：QUESTIONS UNDER STUDY:Deep brain stimulation (DBS) has become a standard therapy for some forms of severe movement disorders and is investigated for other neurological and psychiatric disorders, although many scientific, clinical and ethical issues are still open. We analyse how the Swiss DBS community addresses these ...

journal_title：Swiss medical weekly

authors： Christen M,Müller S

更新日期：2012-04-05 00:00:00

abstract：OBJECTIVE:To evaluate the current prevalence of self-reported interpersonal violence amongst patients consulting at the emergency department (ED) of a university hospital and to describe the characteristics of the violence sustained. METHODS:Ours was a cross-sectional study using a modified version of the Partner Viol...

journal_title：Swiss medical weekly

authors： Douet T,Ohl A,Hügli O,Romain-Glassey N,Carron PN

更新日期：2019-12-17 00:00:00

abstract：BACKGROUND:Campylobacteriosis and salmonellosis are important foodborne diseases in Europe, including in Switzerland. In 2014, notification rates for Switzerland were 92.9 per 100 000 population for campylobacteriosis and 15.2 per 100 000 population for salmonellosis. These notification rates originate from laboratory-...

journal_title：Swiss medical weekly

authors： Bless PJ,Schmutz C,Sartori K,Mäusezahl D

更新日期：2017-12-27 00:00:00

abstract：OBJECTIVE:To analyze the immediate and midterm angiographic and clinical results of stent placement in the endovascular treatment of intracranial cerebral aneurysms. METHODS:Out of 330 cerebral aneurysms treated by endovascular approach in our neurovascular centre, stents have been used in 18 patients. Twelve aneurysm...

journal_title：Swiss medical weekly

authors： Mordasini P,Walser A,Gralla J,Wiest R,Ozdoba C,Reinert M,Schroth G

更新日期：2008-11-01 00:00:00

abstract：:Each year, over 5 million people die worldwide from stroke, and at least every sixth patient who survives will experience another stroke within five years [1]. We are therefore eager to advance early and rapid diagnosis, prognosis and optimal risk stratification, as well as secondary prevention. In this context, blood...

journal_title：Swiss medical weekly

authors： Sonderer J,Katan Kahles M

更新日期：2015-05-29 00:00:00

abstract：:HMG-CoA reductase inhibitors, or statins, are lipid-lowering agents that have been shown to effectively decrease severe rejection periods and development of transplant coronary artery disease after heart transplantation. Precise regulation of major histocompatibility complex class II (MHC class II) gene expression pla...

journal_title：Swiss medical weekly

authors： Kwak B,Mulhaupt F,Veillard N,Pelli G,Mach F

更新日期：2001-01-27 00:00:00

abstract：PRINCIPLES:Drugs that either inhibit prostaglandin synthesis or antagonise angiotensin II effects are likely to impair renal function, especially in patients with an activated renin-angiotensin-aldosterone system. Of the former, nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used, and newer agents with cycloo...

journal_title：Swiss medical weekly

authors： Kistler T,Ambühl PM

更新日期：2001-04-07 00:00:00

abstract：BACKGROUND:Several publications reported on the safety and efficacy of bortezomib, a novel first-in-class anti-cancer agent, in the treatment of relapsed/refractory multiple myeloma in controlled clinical trials. Complementary data on the experience with bortezomib in daily oncology practice are needed. We report on th...

journal_title：Swiss medical weekly

authors： Freimann H,Calderoni A,Cornu P,Olie R

更新日期：2007-06-02 00:00:00

abstract：PRINCIPLES:Analysis of the spatial distribution of mortality data is important for identification of high-risk areas, which in turn might guide prevention, and modify behaviour and health resources allocation. This study aimed to update the Swiss mortality atlas by analysing recent data using Bayesian statistical metho...

journal_title：Swiss medical weekly

authors： Chammartin F,Probst-Hensch N,Utzinger J,Vounatsou P

更新日期：2016-02-22 00:00:00

abstract：BACKGROUND:The number of individuals with autoimmune inflammatory rheumatic diseases (AIIRDs) treated with immunosuppressive drugs is increasing steadily. The variety of immunosuppressive drugs and, in particular, biological therapies is also rising. The immunosuppressants, as well as the AIIRD itself, increase the ris...

journal_title：Swiss medical weekly

authors： Bühler S,Eperon G,Ribi C,Kyburz D,van Gompel F,Visser LG,Siegrist CA,Hatz C

更新日期：2015-07-28 00:00:00

abstract：:Giant cell arteritis (GCA) is the most common of the vasculitis syndromes and, being a disease of the elderly, its incidence is increasing with the general ageing of the population. GCA is most feared for its early complications, namely blindness and stroke, resulting from inflammation and subsequent occlusion of ocul...

journal_title：Swiss medical weekly

authors： Kesten F,Aschwanden M,Gubser P,Glatz K,Daikeler T,Hess C

更新日期：2011-09-28 00:00:00

abstract：QUESTIONS UNDER STUDY / PRINCIPLES:Colonoscopies are complex procedures that depend greatly on the patient's cooperation and on the correct judgment of a tolerable amount of discomfort by the endoscopy team, even in sedated patients. Little is known regarding the accuracy of the patient comfort level assessments made b...

journal_title：Swiss medical weekly

authors： Heuss LT,Sughanda SP,Degen LP

更新日期：2012-11-05 00:00:00

abstract：THEORETICAL BACKGROUND:Mental disorders emerge in childhood and adolescence and are important risk factors for mental disorders in adolescence and adulthood. Since paediatricians are typically the first to see children with psychological problems, the aim of this study was to obtain a survey of mental disorders of chil...

journal_title：Swiss medical weekly

authors： In-Albon T,Zumsteg U,Müller D,Schneider S

更新日期：2010-08-27 00:00:00

abstract：QUESTIONS UNDER STUDY:Paraoxonase-1 (PON1) is an HDL-bound enzyme system which plays a key role in the protection of LDL and HDL from oxidation by hydrolysing activated phospholipids and lipid peroxide products. Oxidative stress has been involved in the pathogenesis of many complications of human pregnancy, including e...

journal_title：Swiss medical weekly

authors： Toy H,Camuzcuoglu H,Celik H,Erel O,Aksoy N

更新日期：2009-02-07 00:00:00

abstract：BACKGROUND:In 2005, findings of the first "cost of disorders of the brain in Europe" study of the European Brain Council (EBC) showed that these costs cause a substantial economic burden to the Swiss society. In 2010 an improved update with a broader range of disorders has been analysed. This report shows the new findi...

journal_title：Swiss medical weekly

authors： Maercker A,Perkonigg A,Preisig M,Schaller K,Weller M,Cost of Disorders of the Brain in Europe Study Group.

更新日期：2013-01-07 00:00:00

abstract：:The authors report on bilateral simultaneous knee arthroplasty in a 40-year-old male patient with haemophilia A, high inhibitor titre and an aneurysma spurium of the right popliteal artery. Both knees showed a fixed flexion deformity of 20 degrees. To build up haemostasis, treatment with activated prothrombin complex ...

journal_title：Swiss medical weekly

authors： Frauchiger LH,Harstall R,Kajahn J,Anderson S,Eggli S

更新日期：2010-08-24 00:00:00

abstract：QUESTIONS UNDER STUDY:In this work we wanted to evaluate the effect of intra-articular injection (IAI) at the knee joint of 1 ml of Diprospan on the hypothalamic-pituitary-adrenal (HPA) axis. METHODS:Consecutive patients attending the rheumatology or orthopaedic clinic with osteoarthritic knee pain not responding sati...

journal_title：Swiss medical weekly

authors： Habib G,Zahran R,Najjar R,Badarny S,Jabbour A,Artul S,Hakim G,Jabaly-Habib H

更新日期：2015-05-21 00:00:00