Hearing in slow-motion: Humans underestimate the speed of moving sounds.

abstract：:This is the first study to investigate the impact of a second fibula flap or a soft tissue flap combined with bridging plate for a repeated segmental mandibulectomy reconstruction on flap outcomes in head and neck cancer patients. A retrospective comparative analysis (2007-2016) of 61 patients who underwent a second s...

journal_title：Scientific reports

authors： Lin JA,Loh CYY,Tsai CH,Chang KP,Wu JC,Kao HK

更新日期：2019-05-28 00:00:00

abstract：:Mitochondrial disorders are among the most prevalent inborn errors of metabolism but largely lack treatments and have poor outcomes. High-fat, low-carbohydrate ketogenic diets (KDs) have shown beneficial effects in mouse models of mitochondrial myopathies, with induction of mitochondrial biogenesis as the suggested ma...

journal_title：Scientific reports

authors： Purhonen J,Rajendran J,Mörgelin M,Uusi-Rauva K,Katayama S,Krjutskov K,Einarsdottir E,Velagapudi V,Kere J,Jauhiainen M,Fellman V,Kallijärvi J

更新日期：2017-04-19 00:00:00

abstract：:DEMETER-like DNA glycosylases (DMLs) initiate the base excision repair-dependent DNA demethylation to regulate a wide range of biological processes in plants. Six putative SmDML genes, termed SmDML1-SmDML6, were identified from the genome of S. miltiorrhiza, an emerging model plant for Traditional Chinese Medicine (TC...

journal_title：Scientific reports

authors： Li J,Li C,Lu S

更新日期：2018-05-08 00:00:00

abstract：:Necrotizing enterocolitis (NEC) is a devastating gastrointestinal emergency of neonates. Epithelial tight junction (TJ) proteins, such as claudins, are essential for regulation and function of the intestinal barrier. Rho kinase (ROCK) affects cellular permeability and TJ regulation. We hypothesized that TJ protein cha...

journal_title：Scientific reports

authors： Ares G,Buonpane C,Sincavage J,Yuan C,Wood DR,Hunter CJ

更新日期：2019-03-21 00:00:00

abstract：:Humans interact with the oceans in diverse and profound ways. The scope, magnitude, footprint and ultimate cumulative impacts of human activities can threaten ocean ecosystems and have changed over time, resulting in new challenges and threats to marine ecosystems. A fundamental gap in understanding how humanity is af...

journal_title：Scientific reports

authors： Halpern BS,Frazier M,Afflerbach J,Lowndes JS,Micheli F,O'Hara C,Scarborough C,Selkoe KA

更新日期：2019-08-12 00:00:00

abstract：:Haloarchaea are unique microorganism's resistant to environmental and osmotic stresses and thrive in their habitats despite extreme fluctuating salinities. In the present study, haloarchaea were isolated from hypersaline thalossohaline salterns of Bhandup, Mumbai, India and were identified as Haloferax prahovense, Hal...

journal_title：Scientific reports

authors： Thombre RS,Shinde VD,Oke RS,Dhar SK,Shouche YS

更新日期：2016-05-27 00:00:00

abstract：:Coleoptera (beetles) is a massively successful order of insects, distinguished by their evolutionarily modified forewings called elytra. These structures are often presumed to have been a major driving force for the successful radiation of this taxon, by providing beetles with protection against a variety of harsh env...

journal_title：Scientific reports

authors： Linz DM,Hu AW,Sitvarin MI,Tomoyasu Y

更新日期：2016-10-06 00:00:00

abstract：:Atmosphere-ocean coupling effect on the frequency distribution of tropical cyclones (TCs) and its future change is studied using an atmosphere and ocean coupled general circulation model (AOGCM). In the present climate simulation, the atmosphere-ocean coupling in the AOGCM improves biases in the AGCM such as the polew...

journal_title：Scientific reports

authors： Ogata T,Mizuta R,Adachi Y,Murakami H,Ose T

更新日期：2016-07-15 00:00:00

abstract：:Fibrosis with excessive amounts of type I collagen is a hallmark of many solid tumours, and fibrosis is a promising target in cancer therapy, but tools for its non-invasive quantification are missing. Here we used magnetic resonance imaging with a gadolinium-based probe targeted to type I collagen (EP-3533) to image a...

journal_title：Scientific reports

authors： Polasek M,Yang Y,Schühle DT,Yaseen MA,Kim YR,Sung YS,Guimaraes AR,Caravan P

更新日期：2017-08-14 00:00:00

abstract：:The expression level of folate receptor alpha (FRα) is located highly rate in ovarian cancer though it is remained absent in normal tissues. This highly tumor restricted expression profile makes FRα a promising target for tumor therapy and diagnosis. In this research we report a FRα binding peptide C7(Met-His-Thr-Ala-...

journal_title：Scientific reports

authors： Xing L,Xu Y,Sun K,Wang H,Zhang F,Zhou Z,Zhang J,Zhang F,Caliskan B,Qiu Z,Wang M

更新日期：2018-05-30 00:00:00

abstract：:Climate change significantly affects geographic distribution of plants pests and diseases worldwide. Understanding the influence of future climate change on the suitable areas of Diaphorina citri (Kuwayama) in our country and taking timely countermeasures are crucial for improving the effectiveness of control of pest....

journal_title：Scientific reports

authors： Wang R,Yang H,Wang M,Zhang Z,Huang T,Wen G,Li Q

更新日期：2020-06-08 00:00:00

abstract：:Diabetes is a chronic metabolic disease that causes blood glucose (BG) concentration to make dangerous excursions outside its physiological range. Measuring the fraction of time spent by BG outside this range, and, specifically, the time-below-range (TBR), is a clinically common way to quantify the effectiveness of th...

journal_title：Scientific reports

authors： Camerlingo N,Vettoretti M,Facchinetti A,Sparacino G,Mader JK,Choudhary P,Del Favero S

更新日期：2020-10-23 00:00:00

abstract：:Symbiodinium is a dinoflagellate that plays an important role in the physiology of the symbiotic relationships of Cnidarians such as corals and sea anemones. However, it is very difficult to cultivate free-living dinoflagellates after being isolated from the host, as they are very sensitive to environmental changes. H...

journal_title：Scientific reports

authors： Pasaribu B,Weng LC,Lin IP,Camargo E,Tzen JT,Tsai CH,Ho SL,Lin MR,Wang LH,Chen CS,Jiang PL

更新日期：2015-10-20 00:00:00

abstract：:Protein ubiquitylation participates in a number of essential cellular processes including signal transduction and transcription, often by initiating the degradation of specific substrates through the 26S proteasome. Within the ubiquitin-proteasome system, deubiquitylating enzymes (DUBs) not only help generate and main...

journal_title：Scientific reports

authors： Hayama R,Yang P,Valverde F,Mizoguchi T,Furutani-Hayama I,Vierstra RD,Coupland G

更新日期：2019-11-19 00:00:00

abstract：:We measured the interleukin-34 (IL-34) level in sera from patients with systemic lupus erythematosus (SLE) and discoid lupus erythematosus (DLE) using an enzyme-linked immunosorbent assay (ELISA). Blood tests, including assays to determine C-reactive protein (CRP), complement (C) 3, C4, immunoglobulin (Ig) A, IgG, IgM...

journal_title：Scientific reports

authors： Xie HH,Shen H,Zhang L,Cui MY,Xia LP,Lu J

更新日期：2018-02-22 00:00:00

abstract：:Novel predictive biomarkers are needed to improve patient selection and optimize the use of bevacizumab (B) in metastatic colorectal cancer. We analyzed the potential of five circulating biomarkers to predict B efficacy and monitor response. Peripheral blood samples collected at baseline, at the first clinical evaluat...

journal_title：Scientific reports

authors： Marisi G,Scarpi E,Passardi A,Nanni O,Ragazzini A,Valgiusti M,Casadei Gardini A,Neri LM,Frassineti GL,Amadori D,Ulivi P

更新日期：2017-05-02 00:00:00

abstract：:Short flashes of blue light (bioluminescence) from dinoflagellates can reduce copepod grazing of light-emitting cells. Other protective strategies against grazing are toxicity, reduced cell chain length and altered swimming patterns in different phytoplankton. Both toxicity and bioluminescence capacity in dinoflagella...

journal_title：Scientific reports

authors： Lindström J,Grebner W,Rigby K,Selander E

更新日期：2017-10-12 00:00:00

abstract：:A new fluorine-substituted ligand, compound 1 (CB251), with a very high affinity (Ki = 0.27 ± 0.09 nM) and selectivity for the 18-kDa translocator protein (TSPO), is presented as an attractive biomarker for the diagnosis of neuroinflammation, neurodegeneration and tumour progression. To test compound 1 as a TSPO PET i...

journal_title：Scientific reports

authors： Perrone M,Moon BS,Park HS,Laquintana V,Jung JH,Cutrignelli A,Lopedota A,Franco M,Kim SE,Lee BC,Denora N

更新日期：2016-02-08 00:00:00

abstract：:Despite recent advances in cancer management and therapy, resistance to cytotoxic medications remains a major clinical challenge; hence, combination-based anti-cancer treatment regimens are currently gaining momentum. PTC-209 reduced BMI1 protein expression, while palbociclib inhibited CDK4, Rb, and pRbSer795 protein ...

journal_title：Scientific reports

authors： Elango R,Vishnubalaji R,Manikandan M,Binhamdan SI,Siyal AA,Alshawakir YA,Alfayez M,Aldahmash A,Alajez NM

更新日期：2019-09-23 00:00:00

abstract：:In yeast, the pol3-01,L612M double mutant allele, which causes defects in DNA polymerase delta (Pol δ) proofreading (pol3-01) and nucleotide selectivity (pol3-L612M), confers an "ultramutator" phenotype that rapidly drives extinction of haploid and diploid MMR-proficient cells. Here, we investigate antimutator mutatio...

journal_title：Scientific reports

authors： Dennis DG,McKay-Fleisch J,Eitzen K,Dowsett I,Kennedy SR,Herr AJ

更新日期：2017-04-18 00:00:00

abstract：:A new approach for achieving two - dimensional (2D) atom localization microscopy based on the projection of three - dimensional (3D) localization in the plane of the detector is described in the present work. Spatial variation of the position-dependent 2D-localization pattern in the xy-plane is obtained with the shift...

journal_title：Scientific reports

authors： Dutta BK,Panchadhyayee P,Bayal I,Das N,Mahapatra PK

更新日期：2020-01-17 00:00:00

abstract：:Detrimental impacts of extreme heats on the U.S. crop yields have been well-documented by a number of empirical studies. However, less have focused on within-growing season weather variation and the interaction between temperature and precipitation. The objective of this study is to emphasize the importance of disaggr...

journal_title：Scientific reports

authors： Yu J,Goh G

更新日期：2019-12-06 00:00:00

abstract：:Omalizumab (OmAb) is a humanized anti-IgE antibody approved for the treatment of chronic spontaneous urticaria (CSU). OmAb's mechanism of action is known to include actions on free IgE and on pre-bound IgE. However, OmAb is equally and rapidly effective against autoimmune and non-autoimmune urticaria where IgE involve...

journal_title：Scientific reports

authors： Serrano-Candelas E,Martínez-Aranguren R,Vega O,Gastaminza G,Bartra J,Audicana MT,Núñez-Córdoba JM,Algorta J,Valero A,Martin M,Ferrer M

更新日期：2017-08-21 00:00:00

abstract：:Peripheral neural signals have the potential to provide the necessary motor, sensory or autonomic information for robust control in many neuroprosthetic and neuromodulation applications. However, developing methods to recover information encoded in these signals is a significant challenge. We introduce the idea of usi...

journal_title：Scientific reports

authors： Koh RGL,Nachman AI,Zariffa J

更新日期：2019-07-31 00:00:00

abstract：:Using Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), previous study showed significant gender differences for cognitive deficits in immediate and delayed memory in schizophrenia patients. However, RBANS does not include reasoning and problem solving, and social cognition. These cognitive f...

journal_title：Scientific reports

authors： Zhang B,Han M,Tan S,De Yang F,Tan Y,Jiang S,Zhang X,Huang XF

更新日期：2017-09-19 00:00:00

abstract：:RBM20 is a major regulator of heart-specific alternative pre-mRNA splicing of TTN encoding a giant sarcomeric protein titin. Mutation in RBM20 is linked to autosomal-dominant familial dilated cardiomyopathy (DCM), yet most of the RBM20 missense mutations in familial and sporadic cases were mapped to an RSRSP stretch i...

journal_title：Scientific reports

authors： Murayama R,Kimura-Asami M,Togo-Ohno M,Yamasaki-Kato Y,Naruse TK,Yamamoto T,Hayashi T,Ai T,Spoonamore KG,Kovacs RJ,Vatta M,Iizuka M,Saito M,Wani S,Hiraoka Y,Kimura A,Kuroyanagi H

更新日期：2018-06-12 00:00:00

abstract：:Circuit QED on a chip has become a powerful platform for simulating complex many-body physics. In this report, we realize a Dicke-Ising model with an antiferromagnetic nearest-neighbor spin-spin interaction in circuit QED with a superconducting qubit array. We show that this system exhibits a competition between the c...

journal_title：Scientific reports

authors： Zhang Y,Yu L,Liang JQ,Chen G,Jia S,Nori F

更新日期：2014-02-13 00:00:00

abstract：:We demonstrate synthesis of Ni/CuOx/Ni nanowires (NWs) by electrochemical deposition on anodized aluminum oxide (AAO) membranes. AAO with pore diameter of ~70 nm and pore length of ~50 μm was used as the template for synthesis of NWs. After deposition of Au as the seed layer, NWs with a structure of Ni/CuOx/Ni were gr...

journal_title：Scientific reports

authors： Park K,Lee JS

更新日期：2016-03-15 00:00:00

abstract：:Human female germline stem cells (FGSCs) have opened new opportunities for understanding human oogenesis, delaying menopause, treating infertility, and providing a new strategy for preserving fertility. However, the shortage of adult human ovaries tissues available impedes their future investigations and clinical appl...

journal_title：Scientific reports

authors： Ding X,Liu G,Xu B,Wu C,Hui N,Ni X,Wang J,Du M,Teng X,Wu J

更新日期：2016-06-30 00:00:00

abstract：:A disposable cyclic voltammetry (CV) tag is printed on a plastic film by integrating wireless power transmitter, polarized triangle wave generator, electrochemical cell and signage through a scalable gravure printing method. By proximity of 13.56 MHz RF reader, the printed CV tag generates 320 mHz of triangular sweep ...

journal_title：Scientific reports

authors： Jung Y,Park H,Park JA,Noh J,Choi Y,Jung M,Jung K,Pyo M,Chen K,Javey A,Cho G

更新日期：2015-01-29 00:00:00