Microarray Analysis Reveals Altered Lipid and Glucose Metabolism Genes in Differentiated, Ritonavir-Treated 3T3-L1 Adipocytes.

abstract：OBJECTIVE:Identifying the genetic variability in vertically transmitted viruses in early infancy is important to understand the disease progression. Being important in HIV-1 disease pathogenesis, vpu gene, isolated from young infants was investigated to understand the viral characteristics. METHOD:Blood samples were o...

journal_title：Current HIV research

authors： Sharma U,Gupta P,Gupta S,Venkatesh S,Husain M

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Although HIV and injury contribute substantially to disease burdens in lowand middle-income countries (LMIC), their intersection is poorly characterized. OBJECTIVE:This systematic review assessed the prevalence and associated mortality impact of HIVseropositivity among injured patients in LMIC. METHODS:A s...

journal_title：Current HIV research

authors： Aluisio AR,Rege S,Stewart BT,Kinuthia J,Levine AC,Mello MJ,Farquhar C

更新日期：2017-11-23 00:00:00

abstract：:HIV-associated neurocognitive disorders (HAND) remain prevalent despite effective combined anti-retroviral therapy (cART). Cognitive function has been shown to inversely correlate with decreased synaptic and dendritic density. In this study, macaques inoculated with SIV were examined over a 3-month course of infection...

journal_title：Current HIV research

authors： Helke KL,Queen SE,Mankowski JL

更新日期：2013-06-01 00:00:00

abstract：:Objective was to assess dietary intake and physical activity in a Canadian population sample of male patients with HIV and metabolic abnormalities and to compare the data to Canadian recommendations. Sixty-five HIV-infected men with at least one feature associated with the metabolic syndrome (insulin resistance, dysli...

journal_title：Current HIV research

authors： Arendt BM,Aghdassi E,Mohammed SS,Fung LY,Jalali P,Salit IE,Allard JP

更新日期：2008-01-01 00:00:00

abstract：:Premature immunosenescence has been reported in different HIV scenarios. However, how premature is the HIV-related immunosenescent phenotype is still unknown. Thus, the aim of this study was to analyze the immunosenescent status of young viraemic naive HIV-infected individuals, with less than four years from infection...

journal_title：Current HIV research

authors： Ferrando-Martínez S,Ruiz-Mateos E,Romero-Sánchez MC,Muñoz-Fernández MÁ,Viciana P,Genebat M,Leal M

更新日期：2011-07-01 00:00:00

abstract：:Neisseria gonorrhoeae (GC), a major cause of pelvic inflammatory disease, can facilitate HIV transmission. In response to GC infection, genital epithelial cells can produce cytokines, chemokines and defensins to modulate HIV infection and infectivity. GC can also induce the production of cytokines and chemokines in mo...

journal_title：Current HIV research

authors： Jarvis GA,Chang TL

更新日期：2012-04-01 00:00:00

abstract：:The human immunodeficiency virus (HIV) is unique in its capacity to produce chronic disease in almost all infected hosts. To accomplish this, it has evolved multiple mechanisms to effectively evade the immune response. HIV encodes at least one protein that makes infected cells resistant to CTL killing by downmodulatin...

journal_title：Current HIV research

authors： Collins KL

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Human milk banking has been promoted to provide donated breast milk for at-risk children whose mothers cannot breastfeed them but this effort was hindered by the advent of HIV epidemic. OBJECTIVE:To estimate the seroprevalence of HIV, syphilis and hepatitis B in the blood of human milk donors registered in ...

journal_title：Current HIV research

authors： Kupek E,Savi EO

更新日期：2017-01-01 00:00:00

abstract：:Over the past 10 years substantial progress has been made in the implementation of prevention of mother-to-child transmission of HIV (PMTCT) interventions in Sub-Saharan Africa (SSA). In spite of this, new pediatric infections remain unacceptably high, contributing the majority (>90%) of the estimated 390,000 infectio...

journal_title：Current HIV research

authors： Aizire J,Fowler MG,Coovadia HM

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to analyze the temporal trends of HIV epidemiology in Turkey from 2011 to 2016. METHODS:Thirty-four teams from 28 centers at 17 different cities participated in this retrospective study. Participating centers were asked to complete a structured form containing questions about epidem...

journal_title：Current HIV research

authors： Erdinc FS,Dokuzoguz B,Unal S,Komur S,Inkaya AC,Inan D,Karaoglan I,Deveci A,Celen MK,Kose S,Erben N,Senturk GC,Heper Y,Kutlu SS,Hatipoglu CA,Sumer S,Kandemir B,Sirmatel F,Bayindir Y,Yilmaz E,Ersoy Y,Kazak E,Yil

更新日期：2020-01-01 00:00:00

abstract：:In the HAART era Kaposi's sarcoma (KS) remains the second most frequent tumor in HIV-infected patients worldwide, and it has become the most common cancer in Sub-Saharan Africa. In western countries the risk for KS in men having sex with men (MSM) is 5 to 10 times higher compared to other groups of individuals practic...

journal_title：Current HIV research

authors： Martellotta F,Berretta M,Vaccher E,Schioppa O,Zanet E,Tirelli U

更新日期：2009-11-01 00:00:00

abstract：:Antiretroviral therapy (ART), for those who have access, has revolutionised the morbidity and mortality consequences of HIV infection. By the end of 2010, 6.6 million people living with HIV in low- and middle-income countries were receiving ART, a dramatic 20-fold increase since 2001, saving millions of lives. In addi...

journal_title：Current HIV research

authors： Sidibe M

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:We studied the clinical presentation, diagnosis, treatment outcome and survival in children with HIV and Tuberculosis (TB) co-infection. METHODS:All HIV infected children with symptoms or signs consistent with tuberculosis were screened. We studied 24 cases of culture confirmed TB from among a cohort of 213...

journal_title：Current HIV research

authors： Kumar A,Upadhyay S,Kumari G

更新日期：2007-09-01 00:00:00

abstract：:The human immunodeficiency virus-1 (HIV-1) Vpr protein plays multiple roles in HIV-1 replication. In early infection, Vpr provides help in the nuclear localization of pre-integration complex. Subsequently, Vpr induces cell cycle arrest of infected cells at G2/M phase. Cell cycle arrest facilitates higher rate of viral...

journal_title：Current HIV research

authors： Pandey RC,Datta D,Mukerjee R,Srinivasan A,Mahalingam S,Sawaya BE

更新日期：2009-03-01 00:00:00

abstract：:A major hurdle in the development of a global HIV-1 vaccine is viral diversity. For close to three decades, HIV vaccine development has focused on either the induction of T cell immune responses or antibody responses, and only rarely on both components. After the failure of the STEP trial, the scientific community con...

journal_title：Current HIV research

authors： Lu S,Grimes Serrano JM,Wang S

更新日期：2010-12-01 00:00:00

abstract：:Most of the HIV-infected long term survivors show strong CD8+ cell noncytotoxic antiviral response (CNAR) that plays as an important factor for maintaining the relative healthy state of infected individuals. HIV infected former blood donors (FBDs) in Anhui, China are the unique population that considered infected by t...

journal_title：Current HIV research

authors： Yuan L,Ma L,Fan X,Feng Y,Peng H,Zhao Q,Ruan Y,Levy JA,Shao Y

更新日期：2009-07-01 00:00:00

abstract：:In HIV-1 infected cells, over 40 different mRNA species are produced by alternative splicing of the single HIV-1 primary RNA transcript. In addition, approximately half of the HIV-1 primary RNA transcripts are not spliced and are exported to the cytoplasm where they serve as mRNA and as genomic RNA. In this article, w...

journal_title：Current HIV research

authors： Stoltzfus CM,Madsen JM

更新日期：2006-01-01 00:00:00

abstract：:To assess the correlation between HIV-1 RNA load in blood and semen by antiretroviral therapy status and the relative penetration of antiretroviral drugs in seminal plasma. We performed a cross-sectional cohort study of 119 HIV-1 subjects divided into three groups according to treatment status. Blood and semen were co...

journal_title：Current HIV research

authors： Chan DJ,Ray JE,McNally L,Batterham M,Smith DE

更新日期：2008-09-01 00:00:00

abstract：PURPOSE:Switch to unboosted atazanavir (ATV) is an attractive option due to convenience and tolerability in HIV-positive patients. With limited available data we investigated the determinants of long-term efficacy and the consequences of virological failure of unboosted atazanavir-based regimens. METHODS:Retrospective...

journal_title：Current HIV research

authors： Bonora S,Calcagno A,Vigano O,Bigliano P,Marinaro L,Colella E,Orofino G,Trentini L,Tettoni MC,D'Avolio A,Mercadante S,Galli M,Di Perri G,Rusconi S

更新日期：2014-01-01 00:00:00

abstract：:Human immunodeficiency virus has evolved several redundant mechanisms to remove its receptor, the CD4 molecule, from the cell surface. Indeed, HIV-1 encodes three proteins, Nef, Vpu and Env, that have a profound effect on CD4 trafficking and catabolism. Given this functional convergence, it is believed that cell surfa...

journal_title：Current HIV research

authors： Levesque K,Finzi A,Binette J,Cohen EA

更新日期：2004-01-01 00:00:00

abstract：:To promote the initiation of reverse transcription, the HIV-1 virus uses a host tRNA as a primer, tRNA(3Lys). The annealing of tRNA(3Lys) to the viral RNA requires the breaking of the 3D structure of the tRNA and RNA rearrangements, to form a stable initiation complex recognised by the reverse transcriptase. The annea...

journal_title：Current HIV research

authors： Tisné C

更新日期：2005-04-01 00:00:00

abstract：:While significant progress has been made since 2003 when a comprehensive treatment, prevention and control program was implemented to combat the HIV/AIDS epidemic in China, new challenges are emerging. There have been limited direct case reports on profiles of HIV/AIDS patients under care at unique clinical settings i...

journal_title：Current HIV research

authors： Jiao Y,Zhang T,Wang S,Liu Q,Zhou H,Lu S,Wu H

更新日期：2010-10-01 00:00:00

abstract：:Antigenic variation, which is the result of amino acid substitution and genetic evolution, poses a major challenge in the development of vaccines against pathogens with unstable genomes, such as HIV-1 and Influenza. Thus, it is highly important to characterize the relationship of genetic evolution, antigenic variation...

journal_title：Current HIV research

authors： Li F,Gilbert PB,Self SG

更新日期：2007-01-01 00:00:00

abstract：:The HIV epidemic has resulted in medical, social and economic consequences. There is general agreement that a safe, effective and affordable preventive HIV vaccine is urgently needed to control the epidemic. To date, over 60 phase I/II trials of about 30 candidate vaccines have been conducted worldwide. In 1991, Thail...

journal_title：Current HIV research

authors： Pitisuttithum P

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to investigate if the supplementation with multistrain probiotics may be able to modulate T cell response in HIV-1 infected patients and to evaluate the anti-HIV activity of probiotic by studying fecal water (FW) samples. METHODS:Three HIV-1-positive patients (Pt1, Pt2 and Pt3) on l...

journal_title：Current HIV research

authors： Falasca F,Cavallari EN,Innocenti GP,Scagnolari C,Mezzaroma I,Santinelli L,Ceccarelli G,Vullo V,Turriziani O,d'Ettorre G

更新日期：2019-01-01 00:00:00

abstract：UNLABELLED:Adolescent girls throughout the globe are particularly vulnerable to HIV infection. In the U.S., sexually-active, adolescent girls in urban settings are at elevated risk for HIV. The purpose of this study was to describe a theoreticallydriven, HIV prevention intervention tailored for adolescent girls and eva...

journal_title：Current HIV research

authors： Morrison-Beedy D,Crean HF,Passmore D,Carey MP

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:HIV infection induces alterations in the gut-associated lymphoid tissue (GALT) that constitutes the most important site for viral replication due to the extensive presence of effector memory T-cells. In the case of HIV-controllers, several studies have reported fewer peripheral alterations and conserved immu...

journal_title：Current HIV research

authors： Taborda NA,Correa LA,Feria MG,Rugeles MT

更新日期：2018-01-01 00:00:00

abstract：:Passive immunization studies in non-human primates have established unequivocally that virus neutralization can prevent infection, providing the impetus for current intense efforts to identify immunogens that elicit broadly neutralizing antibodies in humans. Although Fc-mediated effector function may also contribute t...

journal_title：Current HIV research

authors： Lewis GK

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:A vaccine able to elicit broadly neutralizing antibodies capable of blocking infection by global viruses has not been achieved, and remains a key public health challenge. OBJECTIVE:During infection, a robust strain-specific neutralizing response develops in most people, but only a subset of infected people ...

journal_title：Current HIV research

authors： Moore PL

更新日期：2018-01-01 00:00:00

abstract：:AIDS has claimed the lives of 25 million people worldwide, an additional 40 million people are HIV-infected and new cases are being diagnosed every year. Despite the fact that HAART has moved AIDS from the category of terminal diseases to that of treatable chronic illnesses, its long-term therapeutic success may be co...

journal_title：Current HIV research

authors： Zeinalipour-Loizidou E,Nicolaou C,Nicolaides A,Kostrikis LG

更新日期：2007-07-01 00:00:00