Profile of HIV-1 infected patients from an AIDS clinic in Beijing from 2007-2008.

abstract：:Although hepatitis B serology screening has been recommended for HIV care, it has not been routinely performed. We aimed to assess compliance and timing of hepatitis B serology screening among HIV-infected patients in a resource-limited setting. A cross-sectional study was conducted in Thailand. Compliance, timing of ...

journal_title：Current HIV research

authors： Kiertiburanakul S,Chotiprasitsakul D,Atamasirikul K,Sungkanuparph S

更新日期：2011-01-01 00:00:00

abstract：:Beta defensins are antimicrobial peptides that serve to protect the host from microbial invasion at skin and mucosal surfaces. Here we explore the relationships among beta defensin levels, total bacterial colonization, and colonization by bacterial vaginosis (BV)-related bacteria and lactobacilli in the female genital...

journal_title：Current HIV research

authors： Jiang W,Ghosh SK,Flyckt R,Kalinowska M,Starks D,Jurevic R,Weinberg A,Lederman MM,Rodriguez B

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to investigate if the supplementation with multistrain probiotics may be able to modulate T cell response in HIV-1 infected patients and to evaluate the anti-HIV activity of probiotic by studying fecal water (FW) samples. METHODS:Three HIV-1-positive patients (Pt1, Pt2 and Pt3) on l...

journal_title：Current HIV research

authors： Falasca F,Cavallari EN,Innocenti GP,Scagnolari C,Mezzaroma I,Santinelli L,Ceccarelli G,Vullo V,Turriziani O,d'Ettorre G

更新日期：2019-01-01 00:00:00

abstract：:VGV-1, a clinical-grade formulation of bovine thymus nuclear protein (TNP) has been demonstrated to possess anti-viral activity in HIV-1 patients in five clinical trials, one of which was placebo controlled double-blinded. However, to date molecular mechanisms remain to be identified. Using surface plasmon resonance w...

journal_title：Current HIV research

authors： Mamikonyan G,Kiyatkin A,Movsesyan N,Mkrtichyan M,Ghochikyan A,Petrushina I,Hwang J,Ichim TE,Keledjian H,Agadjanyan MG

更新日期：2008-06-01 00:00:00

abstract：UNLABELLED:Some deficient genetic polymorphisms of the innate immune system have been correlated to a higher susceptibility to different infections, especially in immunocompromised patients. The possible association between an increased incidence of pneumococcal bacteremia in HIV-infected patients, and deficient polymo...

journal_title：Current HIV research

authors： Horcajada JP,Lozano F,Muñoz A,Suarez B,Fariñas-Alvarez C,Almela M,Smithson A,Martínez E,Mallolas J,Mensa J,Gatell JM

更新日期：2009-03-01 00:00:00

abstract：:The cellular protein "Bone marrow stromal antigen 2" (BST2 also called Tetherin, CD317, HM1.24) was identified as a major mediator of the innate immune defense against the dissemination of enveloped viruses. BST2 was shown to physically trap the de novo formed viral particles at the surface of infected cells, thereby ...

journal_title：Current HIV research

authors： Janvier K,Roy N,Berlioz-Torrent C

更新日期：2012-06-01 00:00:00

abstract：:A major focus of HIV-1 vaccine development has been directed towards a limited number of broadly conserved epitopes in the Envelope (Env) proteins that are sensitive neutralization targets in many primary isolates. However, evidence suggests that these epitopes are poorly immunogenic; similar antibodies are rarely pro...

journal_title：Current HIV research

authors： Pinter A

更新日期：2007-11-01 00:00:00

abstract：:The present study assessed the phenotypic aspects of oral-cavity Candida albicans isolates from 300 HIV-1- positive patients, relating the most commonly investigated virulence factors (enzyme typing and germ-tube formation) to the most common morphotypes. The samples were seeded into specific media for isolation and s...

journal_title：Current HIV research

authors： Menezes TO,Gillet LC,Menezes SA,Feitosa RN,Ishak MO,Ishak R,Marques-da-Silva SH,Vallinoto AC

更新日期：2013-06-01 00:00:00

abstract：:In HIV-1 infected cells, over 40 different mRNA species are produced by alternative splicing of the single HIV-1 primary RNA transcript. In addition, approximately half of the HIV-1 primary RNA transcripts are not spliced and are exported to the cytoplasm where they serve as mRNA and as genomic RNA. In this article, w...

journal_title：Current HIV research

authors： Stoltzfus CM,Madsen JM

更新日期：2006-01-01 00:00:00

abstract：:Hodgkin lymphoma (HL) represents one of the most common types of a non-AIDS-defining tumour that occurs in the HIV population, and its incidence is increasing in the post Highly Active Anti-retroviral Therapy (HAART) era. Despite the aggressiveness of that disease, the outcome of patients with HIV-HL has improved with...

journal_title：Current HIV research

authors： Mounier N,Spina M,Spano JP

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:China has implemented a nation-wide policy to control mother-to-child transmission (MTCT) of the human immunodeficiency virus (HIV) since 2011, yet the efficacy of the control policy is less studied. The aim of the present study was to report the data in the prevention of MTCT of HIV in Nantong city, China. ...

journal_title：Current HIV research

authors： Lou H,Ge X,Xu B,Liu W,Zhou YH

更新日期：2020-01-01 00:00:00

abstract：:In HIV-1, tRNA(Lys3) serves as the primer for reverse transcriptase, and during viral assembly, the tRNA(Lys) isoacceptors, tRNA(Lys1,2) and tRNA(Lys3), are selectively packaged into the virion. In this review, we shall first discuss the evidence for the formation of a tRNA(Lys) packaging complex, whose components inc...

journal_title：Current HIV research

authors： Kleiman L,Halwani R,Javanbakht H

更新日期：2004-04-01 00:00:00

abstract：:The HIV epidemic has resulted in medical, social and economic consequences. There is general agreement that a safe, effective and affordable preventive HIV vaccine is urgently needed to control the epidemic. To date, over 60 phase I/II trials of about 30 candidate vaccines have been conducted worldwide. In 1991, Thail...

journal_title：Current HIV research

authors： Pitisuttithum P

更新日期：2005-01-01 00:00:00

abstract：:A major hurdle in the development of a global HIV-1 vaccine is viral diversity. For close to three decades, HIV vaccine development has focused on either the induction of T cell immune responses or antibody responses, and only rarely on both components. After the failure of the STEP trial, the scientific community con...

journal_title：Current HIV research

authors： Lu S,Grimes Serrano JM,Wang S

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Human immunodeficiency virus (HIV) infection is a global health burden which ultimately results in acquired immune deficiency syndrome (AIDS). There are multiple host factors which are capable of limiting HIV-1 replication. One of the most important host factors which inhibit HIV-1 DNA synthesis is the apoli...

journal_title：Current HIV research

authors： Iqbal K,Imran M,Ullah S,Jamal M,Waheed Y

更新日期：2018-01-01 00:00:00

abstract：:In this paper we report the study of tryptophan metabolism via serotonin in ventricular CSF in HIV-1 infection in order to investigate the origin of tryptophan metabolites in the human brain. The patients (n=4) were affected with non-communicating hydrocephalus. One of these also was suffering from HIV-1 infection. Th...

journal_title：Current HIV research

authors： Longatti P,Perin A,Comai S,Bertazzo A,Rizzo V,Costa CV,Allegri G

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:HIV-1 CRF55_01B was first reported in 2013. At present, no report is available regarding this new clade's polymorphisms in its functionally critical regions protease and reverse transcriptase. OBJECTIVE:To identify the diversity difference in protease and reverse transcriptase between CRF55_01B and its pare...

journal_title：Current HIV research

authors： Yu G,Li Y,Huang X,Zhou P,Yan J,Yan X,Fu X,Fang Y,Liu J,Li J,He X,Lin P

更新日期：2020-01-01 00:00:00

abstract：:One of the major obstacles to effective prolonged CD8 T cell control over HIV and other latent infections may be the intrinsic, genetically programmed barrier to unlimited proliferation that is characteristic of all normal human somatic cells. Replicative senescence, characterized extensively in cell culture for a var...

journal_title：Current HIV research

authors： Effros RB

更新日期：2003-04-01 00:00:00

abstract：:Low levels of plasma viremia (below 50 copies/ml of HIV-1 RNA) can be detected in the majority of HIV+ subjects successfully treated with HAART. Aim of our study was to evaluate the impact of different antiretroviral regimens on this residual viremia and on proviral HIV-1 DNA in HAART-treated subjects with plasma HIV ...

journal_title：Current HIV research

authors： Nicastri E,Palmisano L,Sarmati L,D'Ettorre G,Parisi S,Andreotti M,Buonomini A,Pirillo FM,Narciso P,Bellagamba R,Vullo V,Montano M,Di Perri G,Andreoni M

更新日期：2008-05-01 00:00:00

abstract：:Among HIV positive patients, Fine needle aspiration cytology (FNAC) or biopsy for diagnosis of tuberculous lymphadenopathy is often avoided due to an unspoken stigma. Earlier, we had developed a clinical scoring scale for the diagnosis of tuberculous lymphadenitis (TBLN), which had 88% sensitivity and detected no fals...

journal_title：Current HIV research

authors： Purohit SD,Purohit V,Mathur ML

更新日期：2006-10-01 00:00:00

abstract：:We recently described that the chloroxoquinolinic ribonucleoside 6-chloro-1,4-dihydro-4-oxo-1-(beta-D-ribofuranosyl) quinoline-3-carboxylic acid (compound A) inhibits the human immunodeficiency virus type 1 (HIV-1) enzyme reverse transcriptase (RT), and its replication in primary cells. Based on these findings, we per...

journal_title：Current HIV research

authors： Souza TM,Rodrigues DQ,Ferreira VF,Marques IP,da Costa Santos F,Cunha AC,de Souza MC,de Palmer Paixão Frugulhetti IC,Bou-Habib DC,Fontes CF

更新日期：2009-05-01 00:00:00

abstract：:Intensive antiretroviral therapy successfully suppresses viral replication but is unable to eradicate the virus. HIV persists in a small number of resting memory T cells where HIV has been transcriptionally silenced. This review will focus on recent insights into the HIV transcriptional control mechanisms that provide...

journal_title：Current HIV research

authors： Mbonye U,Karn J

更新日期：2011-12-01 00:00:00

abstract：:It has long been recognized that drug metabolism and drug toxicity may vary greatly between individuals, affecting both efficacy and toxicity. Pharmacogenetics could benefit HIV therapeutics because of the high prevalence of drug-related adverse events and the long term nature and complexity of combination therapy. In...

journal_title：Current HIV research

authors： Tozzi V,Libertone R,Liuzzi G

更新日期：2008-11-01 00:00:00

abstract：:Previous studies have demonstrated that nonnucleoside reverse transcriptase (RT) inhibitors (NNRTIs) act as chemical enhancers of human immunodeficiency virus type 1 (HIV-1) RT dimerization. In the current study, we sought to define the role of key residues (101, 103, 108, 181, 188, 190, 225 and 318) in the NNRTI-bind...

journal_title：Current HIV research

authors： Figueiredo A,Zelina S,Sluis-Cremer N,Tachedjian G

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Previous studies have developed methodologies for predicting the number of CD4+ cells from the total leukocyte and lymphocytes count based on mathematical methodologies, obtaining percentages of effectiveness prediction higher than 90% with a value of less than 5000 leukocytes. OBJECTIVE:To improve the meth...

journal_title：Current HIV research

authors： Rodriguez J,Prieto S,Correa C,Melo M,Dominguez D,Olarte N,Suárez D,Aragón L,Torres F,Santacruz F

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Cytokines have been widely demonstrated to involve in the pathogenesis of AIDS and the mechanisms of antiretroviral therapy. Interleukin 27 (IL-27) is a new member of the IL-12 cytokine family and has been shown to interfere HIV-1 virus replication with controversial findings. This study is to investigate th...

journal_title：Current HIV research

authors： Zheng YH,Xiao SL,He B,He Y,Zhou HY,Chen Z,Zheng LW,He M,Wang HY,Lin YH,Cao J

更新日期：2017-01-01 00:00:00

abstract：UNLABELLED:Adolescent girls throughout the globe are particularly vulnerable to HIV infection. In the U.S., sexually-active, adolescent girls in urban settings are at elevated risk for HIV. The purpose of this study was to describe a theoreticallydriven, HIV prevention intervention tailored for adolescent girls and eva...

journal_title：Current HIV research

authors： Morrison-Beedy D,Crean HF,Passmore D,Carey MP

更新日期：2013-10-01 00:00:00

abstract：:AIDS is a globalized infectious disease. In 2014, UNAIDS launched a global project of "90-90-90" to end the HIV epidemic by 2030. The second and third 90 require 90% of HIV-1 infected individuals receiving antiretroviral therapy (ART) and durable virological suppression. However, wide use of ART will greatly increase ...

journal_title：Current HIV research

authors： Zuo L,Peng K,Hu Y,Xu Q

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:Switch to unboosted atazanavir (ATV) is an attractive option due to convenience and tolerability in HIV-positive patients. With limited available data we investigated the determinants of long-term efficacy and the consequences of virological failure of unboosted atazanavir-based regimens. METHODS:Retrospective...

journal_title：Current HIV research

authors： Bonora S,Calcagno A,Vigano O,Bigliano P,Marinaro L,Colella E,Orofino G,Trentini L,Tettoni MC,D'Avolio A,Mercadante S,Galli M,Di Perri G,Rusconi S

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Despite decreasing rates of HIV among many populations, HIV-related health disparities among gay, bisexual and other men who have sex with men persist, with disproportional percentages of new HIV diagnoses among racial and ethnic minority men. Despite increasing awareness of HIV pre-exposure prophylaxis (PrE...

journal_title：Current HIV research

authors： Jaiswal J,Griffin M,Singer SN,Greene RE,Acosta ILZ,Kaudeyr SK,Kapadia F,Halkitis PN

更新日期：2018-01-01 00:00:00