Abstract:
:Hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) associated with chronic rhinosinusitis (CRS) and/or asthma comprises a distinct clinical syndrome referred to as NSAIDs exacerbated respiratory disease (NERD). Patients with NERD tend to have more severe course of both upper (CRS and nasal polyps) and lower airway (asthma) diseases and are usually recalcitrant to conventional treatment modalities. Diagnosing and phenotyping of patients with NERD are critical for prevention of drug-induced adverse reactions and open novel options for management of underlying chronic airway inflammatory diseases. Diagnosis of NERD is based on detailed clinical history confirmed by challenge with aspirin, but new diagnostic approaches are currently being developed. This review article focuses on the diagnostic approach to a patient with CRS and hypersensitivity to NSAIDs, emphasizing the importance of diagnosis for proper patient's management.
journal_name
Curr Allergy Asthma Repjournal_title
Current allergy and asthma reportsauthors
Makowska J,Lewandowska-Polak A,Kowalski MLdoi
10.1007/s11882-015-0552-ysubject
Has Abstractpub_date
2015-08-01 00:00:00pages
47issue
8eissn
1529-7322issn
1534-6315journal_volume
15pub_type
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
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journal_title:Current allergy and asthma reports
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
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更新日期:2001-07-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2002-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:2010-07-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
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更新日期:2006-02-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2018-09-15 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2020-01-10 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2018-01-19 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2020-03-06 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-008-0005-y
更新日期:2008-03-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2015-05-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2019-09-10 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
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更新日期:2003-01-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2017-10-05 00:00:00
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更新日期:2016-07-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2003-05-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
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更新日期:2020-05-19 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
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更新日期:2007-05-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-005-0069-x
更新日期:2005-07-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2006-07-01 00:00:00