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Radiotherapy complements immune checkpoint blockade.

Abstract：

:Adaptive immune resistance ablates effective anti-tumor immune responses. In a recent issue of Nature, Victor and colleagues describe that anti-PD-L1 combats adaptive immune resistance upon localized radiation plus anti-CTLA-4 therapy. The superior activity of radiation and dual immune checkpoint blockade is mediated by non-redundant immune mechanisms in cancer.

journal_name

Cancer Cell

journal_title

Cancer cell

authors

Ngiow SF,McArthur GA,Smyth MJ

doi

10.1016/j.ccell.2015.03.015

subject

Has Abstract

pub_date

2015-04-13 00:00:00

pages

437-8

issue

4

eissn

1535-6108

issn

1878-3686

pii

S1535-6108(15)00103-8

journal_volume

27

pub_type

评论,杂志文章

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