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It's the peptide-MHC affinity, stupid.

Abstract：

:Adoptively transferred T cells can reject large established tumors, but recurrence due to escape variants frequently occurs. In this issue of Cancer Cell, Engels et al. demonstrate that the affinity of the target peptide to the MHC molecule determines whether large tumors will relapse following adoptive T cell therapy.

journal_name

Cancer Cell

journal_title

Cancer cell

authors

Kammertoens T,Blankenstein T

doi

10.1016/j.ccr.2013.04.004

subject

Has Abstract

pub_date

2013-04-15 00:00:00

pages

429-31

issue

4

eissn

1535-6108

issn

1878-3686

pii

S1535-6108(13)00138-4

journal_volume

23

pub_type

评论,杂志文章

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