Gamma-interferon-mediated down-regulation of electrolyte secretion by intestinal epithelial cells: a local immune mechanism?

abstract：:IgG1 is cleaved in vitro by granulocyte elastase into Fc and Fab fragments. The elastase-specific Fc fragment has been previously detected in vivo. Biological activity of the fragments has been described in modulating neutrophil oxidative metabolism and enzyme release. To investigate further effects granulocyte chemot...

journal_title：Scandinavian journal of immunology

authors： Eckle I,Kolb G,Havemann K

更新日期：1991-09-01 00:00:00

abstract：:Entamoeba histolytica can cause invasive disease by disruption of the intestinal barriers and subsequent lysis of the intestinal cells. Adherence to and contact dependent killing of host cells requires the galactose inhibitable lectin. To elucidate the mechanism whereby E. histolytica influences host defence, the auth...

journal_title：Scandinavian journal of immunology

authors： Kim JM,Jung HC,Jin DZ,Im KI,Song IS,Kim CY

更新日期：1997-06-01 00:00:00

abstract：:A method of isolation has been developed to purify mast cells from human lung tissue. The purification steps are: (1) dispersion of human lung tissue in single-cell suspensions by enzymatic digestion, (2) partial purification by counterflow centrifugal elutriation, (3) Percoll gradient centrifugation, and (4) enrichme...

journal_title：Scandinavian journal of immunology

authors： van Overveld FJ,Terpstra GK,Bruijnzeel PL,Raaijmakers JA,Kreukniet J

更新日期：1988-01-01 00:00:00

abstract：:The J-chain content of 3 IgM and 24 IgA preparations was quantitated by an immunochemical technique after reduction with 20mM dithiothreitol. The amounts released ranged from undetectable (less than 0.1 mg) to 7.3 mg per 100 mg of Ig. Most of the J-chain-deficient proteins were monomeric, but four polymeric IgA prepar...

journal_title：Scandinavian journal of immunology

authors： Brandtzaeg P

更新日期：1976-01-01 00:00:00

abstract：:The objective of this study was to evaluate whether major abdominal surgery leads to complement activation and interleukin response and whether the kind of anaesthesia influence complement activation and the release of inflammatory interleukins. The study design was prospective and randomised. Fifty patients undergoin...

journal_title：Scandinavian journal of immunology

authors： Kvarnström AL,Sarbinowski RT,Bengtson JP,Jacobsson LM,Bengtsson AL

更新日期：2012-05-01 00:00:00

abstract：:Two new TCRV beta coding region polymorphisms were identified: V beta 6.9a/b and V beta 21.4a/b. In both cases, a single nucleotide difference gives rise to an amino acid exchange. Genomic typing by the PCR/sequence-specific oligonucleotide probing technique was performed to study a possible contribution of these two ...

journal_title：Scandinavian journal of immunology

authors： Hansen T,Rønningen KS,Ploski R,Kimura A,Thorsby E

更新日期：1992-08-01 00:00:00

abstract：:Allogeneic chimaeras that utilize C.B-17 SCID mice (H-2d) as recipients of MHC mismatched bone marrow from C57B1/6 (H-2b) or SJL/J (H-2s) mice have been used to provide experimental evidence demonstrating the necessity for a direct interaction between an effector T helper and the cytotoxic T-cell precursor in order to...

journal_title：Scandinavian journal of immunology

authors： Lin Y,Langman R,Cohn M

更新日期：1992-05-01 00:00:00

abstract：:The autologous mixed lymphocyte reaction (AMLR) and T-cell subsets defined with monoclonal antibodies were examined in the peripheral blood of six patients with chronic mucocutaneous candidiasis (CMC). The AMLR was deficient in four of six patients when compared with simultaneously studied healthy controls. These pati...

journal_title：Scandinavian journal of immunology

authors： Gupta S

更新日期：1985-06-01 00:00:00

abstract：:A solid-phase radioimmunoassay for detection of circulating C1q-binding immune complexes (IC) or heat-aggregated IgG (delta IgG) is described. Purified human C1q protein was adsorbed to a fixed area of polystyrene tube surface for 1 hr at 22 degrees C, pH 7.3, mu 0.15. Binding of delta IgG or IC to solid-phase C1q at ...

journal_title：Scandinavian journal of immunology

authors： Svehag SE

更新日期：1975-01-01 00:00:00

abstract：:The immunoglobulin (Ig) plasma levels are known to be, at least partially, genetically regulated, but all the genes involved are not known. Interleukin-1 (IL-1) is a potent proinflammatory cytokine able to serve as an adjuvant for immune responses. IL-1alpha gene is polymorphic, and at least one of the polymorphisms h...

journal_title：Scandinavian journal of immunology

authors： Kilpinen S,Laine S,Hulkkonen J,Hurme M

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Immunoglobulin A deficiency (IgAD) is the most common primary immunodeficiency. Although most people with selective IgAD (sIgAD) are asymptomatic, many patients often suffer from recurrent respiratory infections and different allergic disorders. Our aim was to investigate connection between subtypes of sIgAD...

journal_title：Scandinavian journal of immunology

authors： Živković J,Lipej M,Banić I,Bulat Lokas S,Nogalo B,Lulić Jurjević R,Turkalj M

更新日期：2019-12-01 00:00:00

abstract：:Serum and salivary concentrations of immunoglobulin A1 (IgA1) and IgA2 were studied in 105 Icelandic children aged 0-12 years. Serum concentrations of both IgA1 and IgA2 increased slightly (P < 0.001) during childhood. The salivary IgA1/IgA2 ratio tended to decrease during the same period; this trend is less apparent ...

journal_title：Scandinavian journal of immunology

authors： Weemaes C,Klasen I,Göertz J,Beldhuis-Valkis M,Olafsson O,Haraldsson A

更新日期：2003-12-01 00:00:00

abstract：:The specificity of the Fcgamma receptors in normal spleen and liver and in malignant tissues was studied using hemadsorption to cryostat sections. Indicator cells (EA) were sheep erythrocytes (E) sensitized with rabbit IgG antibody (A). The binding of EA to sections of normal and malignant tissues was inhibited by poo...

journal_title：Scandinavian journal of immunology

authors： Matre R

更新日期：1976-01-01 00:00:00

abstract：:We have recently shown that a heat treatment of a murine target cell line, WEHI 164, induces resistance to lysis mediated by tumour necrosis factors alpha (TNF-alpha) and beta (TNF-beta). In the present study the effect of the heat shock of target cells on cytotoxicity mediated by natural killer cells (NK cells), lymp...

journal_title：Scandinavian journal of immunology

authors： Jäättelä M

更新日期：1990-02-01 00:00:00

abstract：:The T-cell differentiation antigen T4/Leu3 has been described as a non-polymorphic molecule important in T-cell recognition of class II major histocompatibility complex antigens. We report the polymorphism of this molecule in black individuals as manifest by a heterogeneity of staining with OKT4 monoclonal antibody. N...

journal_title：Scandinavian journal of immunology

authors： Stohl W,Kunkel HG

更新日期：1984-09-01 00:00:00

abstract：:Coeliac disease (CD) is a very common food-sensitive enteropathy, which is triggered by gluten ingestion and is mediated by CD4(+) T cells. In addition, alterations in the intestinal microbiota that is normally involved in the homeostasis of GALT (gut-associated lymphoid tissue) seem to play a role in CD. In accordanc...

journal_title：Scandinavian journal of immunology

authors： D'Arienzo R,Stefanile R,Maurano F,Mazzarella G,Ricca E,Troncone R,Auricchio S,Rossi M

更新日期：2011-10-01 00:00:00

abstract：:Human peripheral blood monocyte subsets with and without Fc receptor for human IgG are known to suppress (FcR+) and enhance (FcR-) pokeweed mitogen-induced polyclonal immunoglobulin synthesis in vitro. The ability of these subsets to modulate immunoglobulin production in the presence or absence of OKT8+ T cells and un...

journal_title：Scandinavian journal of immunology

authors： Pryjma J,Flad HD,Gruber M,Ernst M

更新日期：1986-07-01 00:00:00

abstract：:During B-cell development in the avian bursa of Fabricius most of the developing B cells die by apoptosis and only a minority survive to emigrate into the periphery. Recently, it has been shown that when developing bursal cells become mature and ready to migrate they start to express chL12 antigen. The expression of t...

journal_title：Scandinavian journal of immunology

authors： Lampisuo M,Arstila TP,Liippo J,Lassila O

更新日期：1998-03-01 00:00:00

abstract：:The effector functions of IgG depend on the presence of carbohydrates attached to asparagine 297 in the Fc-portion. In this report, glycosylation profiles of recombinant wild-type and mutant IgG1 and IgG3 antibodies produced from three cell lines were analysed using LC-ESI-Orbitrap. Clear differences were detected bet...

journal_title：Scandinavian journal of immunology

authors： Vestrheim AC,Moen A,Egge-Jacobsen W,Bratlie DB,Michaelsen TE

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Both C1-inhibitor (C1-INH) and antibodies against the CD18 adhesion molecule have been shown to reduce ischaemia-reperfusion injuries. The objective of this study was to investigate the effect of increased ischaemia times and to determine whether inhibiting C1 or blocking the CD18 function was protective in ...

journal_title：Scandinavian journal of immunology

authors： Nielsen EW,Mollnes TE,Harlan JM,Winn RK

更新日期：2002-12-01 00:00:00

abstract：:Multifactorial involvement in the pathogenesis of autoimmune NZB/W F1 mice has been well documented. To further elucidate the role of cytokines in the disease development of murine lupus, single spleen cells isolated from NZB/W F1 and non-autoimmune C57BL/6 mice were stimulated with T cell mitogens or anti-CD3 antibod...

journal_title：Scandinavian journal of immunology

authors： Lin LC,Chen YC,Chou CC,Hsieh KH,Chiang BL

更新日期：1995-10-01 00:00:00

abstract：:Calf spleen extractive injection (CSEI), extracted from the spleen of healthy cows (within 24 h of birth), is a small peptides enriched extraction while the ratio between peptide and ribose is 76 ± 15.2 mg/μg. CSEI is usually used as an ancillary agent to assist cancer patients with immune dysfunction. The present stu...

journal_title：Scandinavian journal of immunology

authors： Jia D,Lu W,Wang C,Sun S,Cai G,Li Y,Wang G,Liu Y,Zhang M,Wang D

更新日期：2016-07-01 00:00:00

abstract：:The procoagulant activities of non-elicited mouse monocytes/macrophages from four anatomical localizations were compared. These cell populations were further examined for their ability to increase their procoagulant activity on exposure to endotoxin or phytohaemagglutinin (PHA). Peritoneal macrophages exhibited the hi...

journal_title：Scandinavian journal of immunology

authors： Lyberg T,Amlie E,Kaplun A,Prydz H

更新日期：1983-09-01 00:00:00

abstract：:The humoral response against the bacterial polysaccharide antigen alpha(1-->3) dextran (Dex) is controlled by J558 idiotype-(Id) specific T cells. These T cells of which the cell clone 178-4 Ts is a representative by all relevant criteria, recognize J558 Id-bearing B cells in an I-Ed-restricted manner. Costimulation v...

journal_title：Scandinavian journal of immunology

authors： Rademaekers A,Specht C,Kölsch E

更新日期：2001-03-01 00:00:00

abstract：:Anti-inflammation strategy is one of the proposed therapeutic approaches to hepatic fibrosis. T helper (Th) 17 cells, which play a detrimental role in experimental murine models of inflammatory diseases, have been demonstrated to participate in the pathogenesis of liver damage. The inhibitory effect of halofuginone (H...

journal_title：Scandinavian journal of immunology

authors： Liang J,Zhang B,Shen RW,Liu JB,Gao MH,Geng X,Li Y,Li YY,Zhang W

更新日期：2014-03-01 00:00:00

abstract：:Recent studies performed in Seattle, USA have suggested that pretransplant assignment of high or low donor alloreactivity may predict acute graft-versus-host disease (aGvHD) after allogeneic HLA identical marrow transplantation for acute leukaemia. The effect of such pretransplant assignment was studied in a Scandinav...

journal_title：Scandinavian journal of immunology

authors： Johnsen HE,Bostrom L,Moller J,Jorgensen JA,Jensen L,Ringden O

更新日期：1992-03-01 00:00:00

abstract：:Immune complexes were isolated by ultracentrifugation in sucrose gradients (20-65% (w/w]. the centrifugation procedure was demonstrated to be isopycnic. The banding density of the complexes was influenced by the chemical nature and molecular size of the antigen and by the antigen to antibody ratio. The method was appl...

journal_title：Scandinavian journal of immunology

authors： Rødahl E,Iversen OJ,Dalen AB

更新日期：1984-07-01 00:00:00

abstract：:Prognosis in myelodysplastic syndrome (MDS) is not only correlated closely with blast cell count in bone marrow and chromosomal abnormalities but also correlated with decreased leucocyte count and function leading to acquisition of lethal infections. Recently, clinical trials in MDS have focused on the application of ...

journal_title：Scandinavian journal of immunology

authors： Zwierzina H,Holzinger I,Gaggl S,Wolf H,Schöllenberger S,Lam C,Bammer T,Geissler D,Lindley I

更新日期：1993-03-01 00:00:00

abstract：:Phosphorothioate oligodeoxynucleotides (sODNs) can induce T-cell-independent polyclonal activation of human B cells by a mechanism that depends on both sequence and back-bone structure. Because matrix-bound as well as soluble sODNs are mitogenic, this stimulation may result from the engagement of surface receptor(s). ...

journal_title：Scandinavian journal of immunology

authors： Liang H,Reich CF,Pisetsky DS,Lipsky PE

更新日期：2001-12-01 00:00:00

abstract：:Transgenic techniques in inbred mouse strains are powerful tools to investigate the specific roles of genes in biological pathways and disease models. However, there is increasing concern over the influence of a variable genetic background in such experiments. To date there have been few investigations of the immunolo...

journal_title：Scandinavian journal of immunology

authors： Johansson AC,Vestberg M,Holmdahl R

更新日期：2000-07-01 00:00:00