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CD103+ dendritic cells producing interleukin-12 in anticancer immunosurveillance.

Abstract：

:The mechanisms through which tumor antigen-specific T cells are elicited in natural or chemotherapy-induced immunosurveillance have been elusive. In this issue of Cancer Cell, two papers by Broz and colleagues and Ruffell and colleagues delineate an important role for a specific dendritic cell subset characterized by CD103 expression, dependence on transcription factors Batf3 and Irf8, and interleukin-12 production.

journal_name

Cancer Cell

journal_title

Cancer cell

authors

Zitvogel L,Kroemer G

doi

10.1016/j.ccell.2014.10.008

subject

Has Abstract

pub_date

2014-11-10 00:00:00

pages

591-3

issue

5

eissn

1535-6108

issn

1878-3686

pii

S1535-6108(14)00412-7

journal_volume

26

pub_type

评论,杂志文章

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