The establishment of the infant intestinal microbiome is not affected by rotavirus vaccination.

abstract：:The anatomic and functional combinations of cusps and lophs (ridges) define the tooth shape of rodent molars, which distinguishes species. The species-specific cusp patterns result from the spatiotemporal induction of enamel knots (EKs), which require precisely controlled cellular behavior to control the epithelial in...

journal_title：Scientific reports

authors： Li L,Tang Q,Nakamura T,Suh JG,Ohshima H,Jung HS

更新日期：2016-11-28 00:00:00

abstract：:Dumbbell probe (DP) attracts increasing interests in rolling circle amplification (RCA). A universal DP production method through cleavage-ligation of hairpin was proposed and optimized. The production is characterized by restriction endonuclease (RE)-induced cleavage ends ligation. It has the advantage of phosphoryla...

journal_title：Scientific reports

authors： Wei H,Tang S,Hu T,Zhao G,Guan Y

更新日期：2016-07-07 00:00:00

abstract：:Mid-infrared spectroscopy is of great importance in many areas and its integration with thin-film technology can economically enrich the functionalities of many existing devices. In this paper we propose a graphene-based ultra-compact spectrometer (several micrometers in size) that is compatible with complementary met...

journal_title：Scientific reports

authors： Wang X,Chen C,Pan L,Wang J

更新日期：2016-08-30 00:00:00

abstract：:Prenatal ethanol exposure (PEE) is an established risk factor for intrauterine growth retardation. The present study was designed to determine whether PEE can increase the susceptibility of high-fat diet (HFD)-induced metabolic syndrome (MS) in adult offspring in a sex-specific manner, based on a generalized linear mo...

journal_title：Scientific reports

authors： He Z,Li J,Luo H,Zhang L,Ma L,Chen L,Wang H

更新日期：2015-12-03 00:00:00

abstract：:To identify novel phenotypic associations related to Cytochrome P450 Family 2 Subfamily A Member 6 (CYP2A6), we investigated the human phenome in a total of 11,271 individuals. Initially, we conducted a phenome-wide association study in 3,401 nicotine-exposed elderly subjects considering 358 phenotypic traits. We iden...

journal_title：Scientific reports

authors： Polimanti R,Jensen KP,Gelernter J

更新日期：2017-04-21 00:00:00

abstract：:Cytosine methylation at CpG dinucleotides is an epigenetic mechanism that affects the gene expression profiles responsible for the functional differences in various cells and tissues. Although gene expression patterns are dynamically altered in response to various stimuli, the intraindividual dynamics of DNA methylati...

journal_title：Scientific reports

authors： Furukawa R,Hachiya T,Ohmomo H,Shiwa Y,Ono K,Suzuki S,Satoh M,Hitomi J,Sobue K,Shimizu A

更新日期：2016-05-19 00:00:00

abstract：:Regional abnormalities in brain structure and function, as well as disrupted connectivity, have been found repeatedly in adolescents with conduct disorder (CD). Yet, the large-scale brain topology associated with CD is not well characterized, and little is known about the systematic neural mechanisms of CD. We employe...

journal_title：Scientific reports

authors： Jiang Y,Liu W,Ming Q,Gao Y,Ma R,Zhang X,Situ W,Wang X,Yao S,Huang B

更新日期：2016-11-14 00:00:00

abstract：:Hydrogen recovery through solar-driven biomass conversion by photo-fermentative bacteria (PFB) has been regarded as a promising way for sustainable energy production. However, a considerable fraction of organic substrate was consumed for the growth of PFB as biocatalysts, furthermore, these PFB were continuously washe...

journal_title：Scientific reports

authors： Xie GJ,Liu BF,Wang RQ,Ding J,Ren HY,Zhou X,Ren NQ

更新日期：2015-11-05 00:00:00

abstract：:Balance is a very important function that allows maintaining a stable stance needed for many daily life activities and for preventing falls. We investigated whether balance control could be improved by a placebo procedure consisting of verbal suggestion. Thirty healthy volunteers were randomized in two groups (placebo...

journal_title：Scientific reports

authors： Villa-Sánchez B,Emadi Andani M,Menegaldo G,Tinazzi M,Fiorio M

更新日期：2019-04-23 00:00:00

abstract：:CIC-DUX4 sarcoma (CDS) is a group of rare, mesenchymal, small round cell tumours that harbour the unique CIC-DUX4 translocation, which causes aberrant gene expression. CDS exhibits an aggressive course and poor clinical outcome, thus novel therapeutic approaches are needed for CDS treatment. Although patient-derived c...

journal_title：Scientific reports

authors： Oyama R,Takahashi M,Yoshida A,Sakumoto M,Takai Y,Kito F,Shiozawa K,Qiao Z,Arai Y,Shibata T,Araki Y,Endo M,Kawai A,Kondo T

更新日期：2017-07-05 00:00:00

abstract：:Telomere length (TL) is linked to various age-related diseases, but little is known about telomeres in gestational diabetes mellitus (GDM). We surveyed 509 subjects (113 GDM patients and 396 frequency matched controls) in Nanjing Drum Tower Hospital, Jiangsu province of eastern China. Relative telomere length (RTL) of...

journal_title：Scientific reports

authors： Weng Q,Deng K,Wu F,Gan M,Li J,Dai Y,Jiang Y,Chen J,Dai J,Ma H,Hu Z,Shen H,Du J,Hu Y,Jin G

更新日期：2019-06-11 00:00:00

abstract：:Infantile hemangiomas are the most common infantile benign vascular tumor. While most infantile hemangiomas proliferate then involute, some may persist and require treatment for reasons including risk of disfigurement or functional impairment. Treatments currently include observation, pharmacological therapy, laser, c...

journal_title：Scientific reports

authors： Zhang L,Yuan WE,Zheng JW

更新日期：2016-02-15 00:00:00

abstract：:A growing bacterium typically divides into two genetically identical and morphologically similar sister cells and eventually gives rise to a clonal population. Nevertheless, significant phenotypic differentiation among isogenic cells frequently occurs, with the resulting heterogeneity in cellular behavior often ensuri...

journal_title：Scientific reports

authors： Govers SK,Adam A,Blockeel H,Aertsen A

更新日期：2017-08-16 00:00:00

abstract：:Two of the important traits for wheat yield are tiller and fertile tiller number, both of which have been thought to increase cereal yield in favorable and unfavorable environments. A total of 6,349 single nucleotide polymorphism (SNP) markers from the 15 K wheat Infinium array were employed for genome-wide associatio...

journal_title：Scientific reports

authors： Bilgrami SS,Ramandi HD,Shariati V,Razavi K,Tavakol E,Fakheri BA,Mahdi Nezhad N,Ghaderian M

更新日期：2020-08-20 00:00:00

abstract：:Diversification between islands and ecological radiation within islands are postulated to have occurred in the Euphorbia species (sect. Aphyllis subsect. Macaronesicae) on the Canary Islands. In this study, the biogeographical pattern of 11 species of subsect. Macaronesicae and the genetic differentiation among five s...

journal_title：Scientific reports

authors： Sun Y,Li Y,Vargas-Mendoza CF,Wang F,Xing F

更新日期：2016-09-29 00:00:00

abstract：:We evaluated the in-vitro effect of potassium on CD4+ T cells and the role of urinary potassium as a potential biomarker of disease activity in patients with ulcerative colitis (UC). This prospective observational cohort study included healthy controls (n = 18) and UC patients [n = 30, median age: 40 (IQR: 28-46) year...

journal_title：Scientific reports

authors： Goyal S,Rampal R,Kedia S,Mahajan S,Bopanna S,Yadav DP,Jain S,Singh AK,Wari MN,Makharia G,Awasthi A,Ahuja V

更新日期：2017-12-22 00:00:00

abstract：:Many behaviors of cancer, such as progression, metastasis and drug resistance etc., cannot be fully understood by genetic mutations or intracellular signaling alone. Instead, they are emergent properties of the cell community which forms a tumor. Studies of tumor heterogeneity reveal that many cancer behaviors critica...

journal_title：Scientific reports

authors： Zhou JX,Taramelli R,Pedrini E,Knijnenburg T,Huang S

更新日期：2017-08-18 00:00:00

abstract：:The Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) has been counted on for conserving threatened marine fish since it regulates the commercial international trade of these species. Implementation of the international treaty for Mantas included on CITES Appendix II is challengin...

journal_title：Scientific reports

authors： Zeng Y,Wu Z,Zhang C,Meng Z,Jiang Z,Zhang J

更新日期：2016-11-23 00:00:00

abstract：:Pantoea sp. IMH is the only bacterium found in genus Pantoea with a high As resistance capacity, but its molecular mechanism is unknown. Herein, the organization, function, and evolution of ars genes in IMH are studied starting with analysis of the whole genome. Two ars systems - ars1 (arsR1B1C1H1) and ars2 (arsR2B2C2...

journal_title：Scientific reports

authors： Wang L,Zhuang X,Zhuang G,Jing C

更新日期：2016-12-14 00:00:00

abstract：:Olanzapine is a second-generation antipsychotic (AP) drug commonly prescribed for the treatment of schizophrenia. Recently, olanzapine has been found to cause brain tissue volume loss in rodent and primate studies; however, the underlying mechanism remains unknown. Abnormal autophagy and oxidative stress have been imp...

journal_title：Scientific reports

authors： Boz Z,Hu M,Yu Y,Huang XF

更新日期：2020-11-05 00:00:00

abstract：:Motivated from numerous practical applications, the present theoretical and numerical work investigates the nonlinear magnetohydrodynamic (MHD) laminar boundary layer flow of an incompressible, viscous fluid over a porous stretching sheet in the presence of suction/injection (mass transpiration). The flow characterist...

journal_title：Scientific reports

authors： Singh J,Mahabaleshwar US,Bognár G

更新日期：2019-12-06 00:00:00

abstract：:The human hepatoma-derived growth factor (HDGF), containing the chromatin-associated N-terminal PWWP domain capable of binding the SMYD1 promoter, participates in various cellular processes and is involved in human cancers. We report the first crystal structures of the human HDGF PWWP domain (residues 1-100) in a comp...

journal_title：Scientific reports

authors： Chen LY,Huang YC,Huang ST,Hsieh YC,Guan HH,Chen NC,Chuankhayan P,Yoshimura M,Tai MH,Chen CJ

更新日期：2018-01-10 00:00:00

abstract：:Light-sheet microscopy enables considerable speed and phototoxicity gains, while quantitative-phase imaging confers label-free recognition of cells and organelles, and quantifies their number-density that, thermodynamically, is more representative of metabolism than size. Here, we report the fusion of these two imagin...

journal_title：Scientific reports

authors： Subedi NR,Jung PS,Bredeweg EL,Nemati S,Baker SE,Christodoulides DN,Vasdekis AE

更新日期：2020-11-19 00:00:00

abstract：:Tuberculosis, a severe infectious disease caused by the Mycobacterium tuberculosis, arouses huge concerns globally. In this study, a total of 331,594 TB cases in Zhejiang Province were notified during the period of 2009-2018 with the gender ratio of male to female 2.16:1. The notified TB incidences demonstrated a cont...

journal_title：Scientific reports

authors： Liu K,Li T,Vongpradith A,Wang F,Peng Y,Wang W,Chai C,Chen S,Zhang Y,Zhou L,Chen X,Bian Q,Chen B,Wang X,Jiang J

更新日期：2020-05-04 00:00:00

abstract：:Mt. Spurr is the largest active volcano in Alaska of high explosive potential. The most recent activity, including two recent magmatic eruptions in 1953 and 1992, has occurred via the flanking Crater Peak. From 2004 to 2006, strong seismicity, gas flux, and heating were observed in the summit area, which had remained ...

journal_title：Scientific reports

authors： Koulakov I,Smirnov SZ,Gladkov V,Kasatkina E,West M,El Khrepy S,Al-Arifi N

更新日期：2018-11-30 00:00:00

abstract：:Daily sunlight exposure damages the epidermal basement membrane (BM) and disrupts epidermal homeostasis. Inter-follicular epidermal stem cells (IFE-SCs) regulate epidermal proliferation and differentiation, which supports epidermal homeostasis. Here, we examine how photoaging affects the function of IFE-SCs and we ide...

journal_title：Scientific reports

authors： Iriyama S,Yasuda M,Nishikawa S,Takai E,Hosoi J,Amano S

更新日期：2020-07-28 00:00:00

abstract：:Porphyry systems supply most copper and significant gold to our economy. Recent studies indicate that they are frequently associated with high Sr/Y magmatic rocks, but the meaning of this association remains elusive. Understanding the association between high Sr/Y magmatic rocks and porphyry-type deposits is essential...

journal_title：Scientific reports

authors： Chiaradia M,Ulianov A,Kouzmanov K,Beate B

更新日期：2012-01-01 00:00:00

abstract：:L-Ascorbic acid (vitamin C, AA) exhibits anti-cancer effects with high-dose treatment through the generation of reactive oxygen species (ROS) and selective damage to cancer cells. The anti-cancer effects of L-ascorbic acid are determined by sodium-dependent vitamin C transporter 2 (SVCT-2), a transporter of L-ascorbic...

journal_title：Scientific reports

authors： Cho S,Chae JS,Shin H,Shin Y,Song H,Kim Y,Yoo BC,Roh K,Cho S,Kil EJ,Byun HS,Cho SH,Park S,Lee S,Yeom CH

更新日期：2018-07-27 00:00:00

abstract：:One strategy to address new potential dangers is to generate defensive responses to stimuli that remind learned threats, a phenomenon called fear generalization. During a threatening experience, the brain encodes implicit and explicit memory traces. Nevertheless, there is a lack of studies comparing implicit and expli...

journal_title：Scientific reports

authors： Manassero E,Mana L,Concina G,Renna A,Sacchetti B

更新日期：2019-09-16 00:00:00

abstract：:The recent discovery that human noroviruses (huNoVs) recognize sialic acids (SAs) in addition to histo-blood group antigens (HBGAs) pointed to a new direction in studying virus-host interactions during calicivirus infection. HuNoVs remain difficult to study due to the lack of an effective cell culture model. In this s...

journal_title：Scientific reports

authors： Tan M,Wei C,Huang P,Fan Q,Quigley C,Xia M,Fang H,Zhang X,Zhong W,Klassen JS,Jiang X

更新日期：2015-07-06 00:00:00